Scilex Holding Company Announces that its Majority Stockholder, Sorrento Therapeutics, Inc., has Issued a Supplement to its Previously Issued “FAQ” Regarding the Dividend of Scilex Holding Company Common Stock

PALO ALTO, Calif., Feb. 02, 2023 (GLOBE NEWSWIRE) — Scilex Holding Company (Nasdaq: SCLX) announced that its majority stockholder, Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”) today posted a supplement to its previously issued “Frequently Asked Questions” document under the “Investors” section of its website at www.sorrentotherapeutics.com regarding its recent dividend to Sorrento stockholders of shares of common stock of Scilex Holding Company held by Sorrento.

The supplement to the FAQs provides notice regarding the Depository Trust and Clearing Corporation’s removal of the contra-CUSIP on Scilex common stock that was distributed as a dividend to Sorrento’s stockholders and provides notice to brokerage firms, banks, dealers and similar organizations listed therein that a dividend confirmation had previously been distributed to such firms by Scilex’s transfer agent and requests that such firms contact Scilex’s transfer agent if they have not received such confirmation. The supplement also reiterates a question related to issues that may arise with respect to the dividend in connection with short positions in Sorrento common stock.

The supplement to the FAQs and related annex are included in this press release and can also be found Scilex’s website https://www.scilexholding.com/investors/faqs/

SUPPLEMENT TO

FREQUENTLY ASKED QUESTIONS

REGARDING THE DIVIDEND OF SCILEX HOLDING COMPANY COMMON STOCK BY SORRENTO THERAPEUTICS, INC.

This supplement is a supplement to the Frequently Asked Questions Regarding the Dividend of Scilex Holding Company Common Stock by Sorrento Therapeutics, Inc. (Sorrento) that was issued by Sorrento on January 29, 2023 (the FAQ), a copy of which can be found under the “Investors” section of its website at www.sorrentotherapeutics.com.

This supplement is being issued to update and supplement the information in the FAQ to notify investors regarding certain matters relating to the dividend and reiterate certain questions and answers from the FAQ. Capitalized terms used in this supplement shall have their respective meetings set forth in the FAQ.

NOTICE OF REMOVAL OF CONTRA-CUSIP BY DTCC

Effective as of February 2, 2023, the Depository Trust and Clearing Corporation has removed the “contra-CUSIP” that it had previously imposed on the Dividend Stock. Any shares of Dividend Stock held by your brokerage firm, bank, dealer or other similar organization for your benefit now bear only Scilex’s CUSIP number, which is 80880W106. If you are entitled to receive Dividend Stock, please contact your brokerage firm, bank, or other similar organization immediately to confirm that the CUSIP number appears on your brokerage statement with respect to your Dividend Stock.

NOTICE TO BROKERAGE FIRMS, BANKS, DEALERS AND OTHER SIMILAR ORGANIZATIONS

If the name of your firm, bank or other similar organization is set forth on Annex B of the FAQ, which Annex B is repeated below for convenience, and your firm, bank or similar organization has not received the Dividend Confirmation that was mailed to your firm, bank or similar organization, please contact Scilex’s transfer agent immediately to obtain a copy of the Dividend Confirmation. Scilex’s transfer agent’s contact information is as follows:

Continental Stock Transfer & Trust Company

Telephone Number: 800-509-5586

Email Address: [email protected]

Several major brokers have confirmed to Sorrento and Scilex that they are adding the Scilex share positions to the individual brokerage accounts of Sorrento shareholders receiving the Dividend Stock

SUPPLEMENTAL QUESTION AND ANSWER

Q: If I loaned my shares of Sorrento common stock to short sellers or any other party as of the Record Date, am I still entitled to receive Dividend Stock as of the Payment Date? 

A: Only Record Holders as of the Record Date are entitled to receive the Dividend Stock. If you were the Record Holder as of the Record Date and are entitled to receive the Dividend Stock, but have not received the Dividend Stock, you may be entitled to receive Dividend Stock from the short seller or other party who borrowed your shares of Sorrento common stock, whether through the lending programs implemented by your brokerage firm, bank, dealer and other similar organization or otherwise. If you were a Record Holder as of the Record Date and have not received your Dividend Stock, please consult with your financial advisor, broker or other agent immediately to determine how to receive your Dividend Stock.

Annex B

Broker List


Broker Name

Broker Address
 
Broker Name

Broker Address
ABN AMRO CLEARING CHICAGO LLC 175 WEST JACKSON BLVD.
CHICAGO
IL ILLINOIS
60604 US
  Albert Fried & Company LLC 45 BROADWAY, 24TH FLOOR
24TH FLOOR
NEW YORK
NY NEW YORK
10006 US
AMALGAMATED BANK 275 7TH AVENUE
NEW YORK
NY NEW YORK
10003 US
  AMERICAN ENTERPRISE INVESTMENT SERVICES INC. 682 AMERIPRISE FINANCIAL CENTER
MINNEAPOLIS
MN MINNESOTA
55474 US
APEX CLEARING CORPORATION 2 GATEWAY CENTER 283-299 MARKET ST
16TH FLOOR
NEWARK
NJ NEW JERSEY
07102-5005 US
  BANK OF AMERICA, NA/GWIM TRUST OPERATIONS 901 MAIN STREET
12TH FLOOR
DALLAS
TX TEXAS
23113 US
BANK OF NEW YORK MELLON 111 SANDERS CREEK PARKWAY 2ND FLOOR
2ND FLOOR
EAST SYRACUSE
NY NEW YORK
13057 US.
  BARCLAYS CAPITAL INC. DTC CUSTODY PARTICIPANT- NY WINDOW -570 WASHINGTON BLVD (ATTN: ROSA HICKS-MILLER OR ROBERT MENDEZ
JERSEY CITY
NJ NEW JERSEY
07310 US
BARCLAYS CAPITAL INC. DTC CUSTODY PARTICIPANT- NY WINDOW -570 WASHINGTON BLVD (ATTN: ROSA HICKS-MILLER OR ROBERT MENDEZ
JERSEY CITY
NJ NEW JERSEY
07310 US
  BMO CAPITAL MARKETS CORP. 3 2ND STREET
12TH FLOOR
JERSEY CITY
NJ NEW JERSEY
07302 US
BMO HARRIS BANK NA/TRUST 11270 W PARK PL
MILWAUKEE
WI WISCONSIN
53224 US
  BMO Nesbitt Burns Inc., Toronto 250 YONGE STREET, 7TH FLOOR
7TH FLOOR
TORONTO
ON ONTARIO
M5B 2M8 CA CANADA
BNP PARIBAS, NEW YORK BRANCH/BNP PARIBAS PRIME BROKERAGE CUSTODIAN 100 WEST 33RD STREET
3RD FLOOR
NEW YORK
NY NEW YORK
10001
  BNP PARIBAS, NEW YORK BRANCH/BNP PARIBAS PRIME BROKERAGE CUSTODIAN 100 WEST 33RD STREET
3RD FLOOR
NEW YORK
NY NEW YORK
10001
BNY MELLON PO BOX 392002
500 ROSS STREET
PITTSBURGH
PA PENNSYLVANIA
15262 US
  BNY MELLON/WEALTH MANAGEMENT 1 FREEDOM VALLEY DRIVE
OAKS
PA PENNSYLVANIA
19456 US
BNYMELLON 111 SANDERS CREEK PARKWAY 2ND FLOOR
2ND FLOOR
EAST SYRACUSE
NY NEW YORK
13057 US
  BNYMELLON/RE BARCLAYS CAPITAL SECURITIES LTD. ONE WALL STREET
NEW YORK
NY NEW YORK
10286
BNYMELLON/RE CACEIS BANK LUXEMBOURG 500 Grant St.
BNY Mellon Center
PITTSBURGH
PA PENNSYLVANIA
15258
  BNYMELLON/RE CACEIS BANK, NETHERLANDS 111 SANDERS CREEK PARKWAY
EAST SYRACUSE
NY NEW YORK
13057
BNYMELLON/RE CHARLES STANLEY AND COMPANY, LIMITED 111 SANDERS CREEK PARKWAY 2ND FLOOR
2ND FLOOR
EAST SYRACUSE
NY NEW YORK
13057 US
  BNYMELLON/RE ETF – ISHARES DTC/NSCC 111 SANDERS CREEK PARKWAY
EAST SYRACUSE
NY NEW YORK
13057
BNYMELLON/RE WINTERFLOOD SECURITIES LTD 500 Grant St.
BNY Mellon Center
PITTSBURGH
PA PENNSYLVANIA
15258
  BOFA 4804 Deer Lake Drive East
FL9-803-04-04- 4th floor
JACKSONVILLE
FL FLORIDA
32246 US
BOFA 4804 Deer Lake Drive East
FL9-803-04-04- 4th floor
JACKSONVILLE
FL FLORIDA
32246 US
  BOFA SECURITIES INC 4804 Deer Lake Drive East
FL9-803-04-04- 4th floor
JACKSONVILLE
FL FLORIDA
32246 US
BROWN BROTHERS HARRIMAN & CO. 140 BROADWAY
ATTN: CORPORATE ACTIONS VAULT
NEW YORK
NY NEW YORK
10005 US
  BROWN BROTHERS HARRIMAN & CO./ETF 140 BROADWAY
NEW YORK
NY NEW YORK
10005
CALDWELL SECURITIES LTD./CDS** 55 UNIVERSITY AVENUE
SUITE 340
TORONTO
ON ONTARIO
M5J 2H7 CANADA
  CANACCORD GENUITY CORP. 609 GRANVILLE ST
VANCOUVER
BC BRITISH COLUMBIA
V7Y 1H2 CA CANADA
CANTOR, FITZGERALD & CO. 135 E 57TH ST 5TH FL
NEW YORK
NY NEW YORK
10041 US
  CDS CLEARING AND DEPOSITORY SERVICES INC. 100 ADELAIDE STREET WEST
TORONTO
ON ONTARIO
M5H 1S3 CA CANADA
CETERA INVESTMENT SERVICES LLC 400 FIRST STREET SOUTH, SUITE 300
SUITE 300
ST. CLOUD
MN MINNESOTA
56302-0283 US
  CHARLES SCHWAB & CO., INC. 211 MAIN STREET
SAN FRANCISCO
CA CALIFORNIA
94105 US
CI INVESTMENT SERVICES INC. 199 BAY STREET
SUITE 2600
TORONTO
ON ONTARIO
M5L 1E2 CA CANADA
  CIBC WORLD MARKETS INC./CDS** 161 BAY STREET 10 FL
TORONTO
ON ONTARIO
M5J 2S8 CA CANADA
CITIBANK, N.A./ETF 3800 CITIGROUP CENTER
B2/2
TAMPA
FL FLORIDA
33610
  CITIBANK, NATIONAL ASSOCIATION 3800 CITIBANK CENTER TAMPA
BLDG.B FIRST FLOOR ZONE 8
TAMPA
FL FLORIDA
33610-9122 US
CITIGROUP GLOBAL MARKETS, INC. 580 CROSSPOINT PARKWAY
GETZVILLE
NY NEW YORK
14068 US
  CLEAR STREET LLC 4 World Trade Center, 45th Floor
150 Greenwich Street
NEW YORK
NY NEW YORK
10007
CLEARSTREET IO 55 BROADWAY (SUITE 2102)
CORPORATE ACTIONS
NEW YORK
NEW YORK
10006 US
  COMMERCE BANK 922 WALNUT STREET
MAIL STOP TBTS-2
KANSAS CITY
MO MISSOURI
64106 US
COR CLEARING LLC 9300 UNDERWOOD AVE
SUITE 400
OMAHA
NE NEBRASKA
68114 US
  Credential Securities Inc. 800-1111 WEST GEORGIA STREET
VANCOUVER
BC BRITISH COLUMBIA
V6E 4T6 CA CANADA
CREST INTERNATIONAL NOMINEES LIMITED 33 CANNON STREET
LONDON
EC4M 5SB GB UNITED KINGDO
  CURVATURE SECURITIES, LLC 39 MAIN STREET
CHATHAM
NJ NEW JERSEY
07928 US
D.A. DAVIDSON & CO. 8 3RD STREET NORTH
GREAT FALLS
MT MONTANA
59401 US
  DEPOSITO CENTRAL DE VALORES S.A., DEPOSITO DE VALORES AVENIDA APOQUINDO # 4001
FLOOR 12, C.P.
7550162, SANTIAGO
CL CHILE
DESJARDINS SECURITIES INC. 1253 McGill College
10TH FLOOR
MONTREAL
QUEBEC
H3B 2Y5 CA CANADA
  DEUTSCHE BANK AG NY/US CUSTODY 1251 Avenue Of The Americas
NEW YORK
NY NEW YORK
10020
DEUTSCHE BANK SECURITIES INC. 60 WALL STREET
9TH FLOOR
NEW YORK
NY NEW YORK
10005 US
  DRIVEWEALTH, LLC 15 EXCHANGE PLACE
10TH FLOOR
JERSEY CITY
NEW JERSEY
07302
E*TRADE CLEARING LLC HARBORSIDE FINANCIAL CENTER
501 PLAZA 11
JERSEY CITY
NJ NEW JERSEY
07311 US
  EDWARD D. JONES & CO., L.P. 12555 MANCHESTER ROAD
ST. LOUIS
MO MISSOURI
63131-3729 US
EDWARD D. JONES & CO., L.P. 201 PROGRESS PARKWAY
MARYLAND HEIGHTS
MO MISSOURI
63043 US
  FIDELITY CLEARING CANADA ULC/CDS** 483 BAY ST.
SOUTH TOWER
TORONTO
ON ONTARIO
M5G2N7 CA CANADA
FIFTH THIRD BANK 5001 KINGSLEY DRIVE
MAIL DROP 1MOB28
CINCINNATI
OH OHIO
45227 US
  FOLIO INVESTMENTS, INC. 8180 GREENSBORO DRIVE
8TH FLOOR
MCLEAN
VA VIRGINIA
22102 US
FUTU CLEARING INC. 12750 Merit Drive
SUITE 475
DALLAS
TX TEXAS
75251
  GMP SECURITIES L.P. 145 KING STREET WEST, SUITE 300
11TH FLOOR
TORONTO
ON ONTARIO
MJ5 1J8 CA CANADA
GOLDMAN, SACHS & CO. LLC 222 SOUTH MAIN STREET
Attn: Mandatory Corporate Actions
SALT LAKE CITY
UT UTAH
84101 US
  HAYWOOD SECURITIES INC./CDS** 200 BURRARD ST
WATERFRONT CENTRE SUITE 700
VANCOUVER
BC BRITISH COLUMBIA
V6C 3L6 CANADA
HILLTOP SECURITIES INC. 1201 ELM ST.
35TH FLOOR
DALLAS
TX TEXAS
75270 US
  HRT FINANCIAL LLC 150 GREENWICH STREET (ATTN: SETTLEMENT) FOUR WORLD TRADE CENTER
57TH FLOOR
NEW YORK
NY NEW YORK
10007 US
HSBC BANK USA, NA/HSBC CUSTODY & CLEARING SERVICES FOR STOCK LOAN 452 FIFTH AVENUE
ATTN: HBUS CCS SETTS
NEW YORK
NY NEW YORK
10018 US
  HSBC BANK USA, NATIONAL ASSOCIATION 452 FIFTH AVENUE
ATTN: HBUS CCS SETTS
NEW YORK
NEW YORK
10018 US
INTERACTIVE BROKERS LLC 2 PICKWICK PLAZA
2ND FLOOR
GREENWICH
CT CONNECTICUT
06830 US
  J.P. MORGAN CHASE BANK NA/FBO BLACKROCK CTF 1111 POLARIS PARKWAY
COLUMBUS
OH OHIO
43240
J.P. MORGAN CLEARING CORP. FOUR CHASE METROTECH CENTER
3RD FLOOR
BROOKLYN
NY NEW YORK
11201 US
  JANNEY MONTGOMERY SCOTT LLC 1717 ARCH STREET
17TH FLOOR
PHILADELPHIA
PA PENNSYLVANIA
19103 US
JEFFERIES LLC 101 HUDSON STREET, 11th Floor
NEW JERSEY
NJ NEW JERSEY
07302 US
  JPMORGAN CHASE BANK, NATIONAL ASSOCIATION FOUR CHASE METROTECH CENTER
3RD FLOOR
BROOKLYN
NY NEW YORK
11201 US
JPMORGAN CHASE BANK/EUROCLEAR BANK FOUR CHASE METROTECH CENTER
3RD FLOOR
BROOKLYN
NY NEW YORK
11245 US
  JPMORGAN CHASE BANK/IA FOUR CHASE METROTECH CENTER
3RD FLOOR
BROOKLYN
NY NEW YORK
11201 US
KEYBANK NATIONAL ASSOCIATION 4900 TIEDEMAN RD
BROOKLYN
OH OHIO
44144 US
  LAURENTIAN BANK SECURITIES INC. 1981 MCGILL COLLEGE AVE.
SUITE 100
MONTREAL
QUEBEC
H3A 3K3 CA CANADA
LPL FINANCIAL LLC 4707 EXECUTIVE DRIVE
SAN DIEGO
CA CALIFORNIA
92121 US
  MANUFACTURERS AND TRADERS TRUST COMPANY ONE M&T PLAZA
TRUST OPS 8TH FLOOR
BUFFALO
NY NEW YORK
14203 US
MANULIFE SECURITIES INCORPORATED 1235 NORTH SERVICE ROAD WEST
OAKVILLE
ON ONTARIO
L6M 2W2 CA CANADA
  MARSCO INVESTMENT CORPORATION 101 EISENHOWER PARKWAY
ROSELAND
NJ NEW JERSEY
07068 US
MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATED 4804 Deer Lake Drive East
FL9-803-04-04- 4th floor
JACKSONVILLE
FL FLORIDA
32246 US
  MIRAE ASSET SECURITIES (USA) INC./STOCK LOAN CONDUIT ACCOUNT 810 SEVENTH AVE
37TH FLOOR
NEW YORK
NY NEW YORK
10019
MIRAE ASSET SECURITIES (USA), INC. 810 SEVENTH AVE
37TH FLOOR
NEW YORK
NY NEW YORK
10019
  MITSUBISHI UFJ TRUST & BANKING CORPORATION, NEW YORK BRANCH 280 PARK AVE
39TH FL-WEST BLDG
NEW YORK
NY NEW YORK
10017
Morgan Stanley 1300 THAMES STREET
THAMES STREET WHARF
BALTIMORE
MD MARYLAND
21231 US
  MORGAN STANLEY & CO. LLC 1300 THAMES ST.
BALTIMORE
MD MARYLAND
MORGAN STANLEY SMITH BARNEY LLC 1 NEW YORK PLAZA
39TH FLOOR
NEW YORK
NY NEW YORK
10004 US
  MURIEL SIEBERT & CO., INC. 77 SUMMER STREET
3RD FLOOR
BOSTON
MA MASSACHUSETTS
02210 US
NATIONAL FINANCIAL SERVICES LLC 499 WASHINGTON BOULEVARD
5TH FLOOR
JERSEY CITY
NJ NEW JERSEY
07310 US
  NBCN INC. 1010 rue De La Gauchetière
Mezzanine 100
MONTREAL
QUEBEC
H3B 5J2 CA CANADA
NOMURA INTERNATIONAL TRUST COMPANY 309 WEST 49TH STREET
10TH FLOOR
NEW YORK
NY NEW YORK
10019 US
  ODLUM BROWN LIMITED 250 HOWE STREET
SUITE 1100
VANCOUVER
BC BRITISH COLUMBIA
V6C 3R8 CA CANADA
OPPENHEIMER & CO. INC. 85 BROAD STREET
NEW YORK
NY NEW YORK
10004 US
  PERSHING LLC 1 PERSHING PLAZA
JERSEY CITY
NJ NEW JERSEY
07399 US
PHILLIP CAPITAL INC. 141 W. JACKSON BLVD. SUITE 3050
CHICAGO
IL ILLINOIS
60604 US
  PI FINANCIAL CORP. 666 BURRARD ST
SUITE 1900
VANCOUVER
BC BRITISH COLUMBIA
V6C 3N1 CA CANADA
PNC BANK, NATIONAL ASSOCIATION 4100 W 150TH STREET
ASSET MOVEMENT TEAM 3RD FL, LOCATOR B7-YB17-03-03
CLEVELAND
OH OHIO
44135 US
  PRINCIPAL BANK 711 HIGH STREET
DES MOINES
IA IOWA
50392
QUESTRADE INC./CDS** 5650 YONGE ST.,
Suite 1700
TORONTO
ON ONTARIO
M2M 4G3 CA CANADA
  Raymond James & Associates, Inc. 880 CARILLON PKWY
ST. PETERSBURG
FL FLORIDA
33733-2749 US
RAYMOND JAMES LTD. 925 WEST GEORGIA STREET
SUITE 2200
VANCOUVER
BC BRITISH COLUMBIA
V6C 3L2 CA CANADA
  RBC CAPITAL MARKETS, LLC 60 SOUTH 6TH ST.
MINNEAPOLIS
MN MINNESOTA
55402 US
RBC DOMINION SECURITIES INC 21 COMMERCE COURT SOUTH
2ND FLOOR
TORONTO
ON ONTARIO
M5L 1A7 CANADA
  RELIANCE TRUST COMPANY 1100 ABERNATHY RD.
500 NORTHPARK SUITE 400
ATLANTA
GA GEORGIA
30113 US
RELIANCE TRUST COMPANY 4900 W. BROWN DEER RD
MILWAUKEE
WI WISCONSIN
53223 US
  ROBERT W. BAIRD & CO. INCORPORATED 777 E WISCONSIN AVE
9TH FLOOR
MILWAUKEE
WI WISCONSIN
53202 US
ROBINHOOD SECURITIES, LLC 500 COLONIAL CENTER PARKWAY
SUITE 100
LAKE MARY
FL FLORIDA
32746 US
  SAFRA SECURITIES LLC 546 5TH AVENUE
NEW YORK
NY NEW YORK
10036 US
SCOTIA CAPITAL (USA) INC. 150 KING STREET W
5TH FLOOR
TORONTO
ON ONTARIO
M5H 1J9 CA CANADA
  SEI PRIVATE TRUST COMPANY 1 FREEDOM VALLEY DRIVE
OAKS
PA PENNSYLVANIA
19456 US
SEI PRIVATE TRUST COMPANY 1 FREEDOM VALLEY DRIVE
OAKS
PA PENNSYLVANIA
19456 US
  SG AMERICAS SECURITIES, LLC 480 WASHINGTON BLVD.
20TH FLOOR
JERSEY CITY
NJ NEW JERSEY
07310 US
SSB – BLACKROCK INSTITUTIONAL TRUST 50 California Street
San Francisco
CA CALIFORNIA
94163
  SSB – TRUST CUSTODY 30 ADELAIDE ST EAST
SUITE 800
TORONTO
ON ONTARIO
M5C 3G6 CA CANADA
SSB&T CO/CLIENT CUSTODY SERVICES 1776 HERITAGE DRIVE
NORTH QUINCY
MA MASSACHUSETTS
02171
  STATE STREET BANK & TRUST CO 16 WALL STREET
5TH FLOOR
NEW YORK
NY NEW YORK
10005 US
STATE STREET BANK & TRUST COMPANY / ISHARES EUROPE 1776 HERITAGE DRIVE
NORTH QUINCY
MA MASSACHUSETTS
02171
  STATE STREET BANK & TRUST/STATE STREET TOTALETF 1776 Heritage Drive
NORTH QUINCY
MA MASSACHUSETTS
02717
STATE STREET BANK AND TRUST COMPANY 30 ADELAIDE ST EAST
SUITE 800
TORONTO
ON ONTARIO
M5C 3G6 CA CANADA
  STIFEL, NICOLAUS & COMPANY, INCORPORATED 501 N BROADWAY
ST. LOUIS
MO MISSOURI
63102 US
STONEX FINANCIAL INC. 2 PERIMETER PARK SOUTH
SUITE 100 W
BIRMINGHAM
AL ALABAMA
35243 US
  TD AMERITRADE CLEARING, INC. 200 S 108TH AVE
OMAHA
NE NEBRASKA
68154 US
TD WATERHOUSE CANADA INC
ATTN: MANDATORY CORPORATE ACTIONS
77 BLOOR STREET WEST
3RD FLOOR
TORONTO
ON ONTARIO
M5S 1M2 CA CANADA
  TEXAS TREASURY SAFEKEEPING TRUST COMPANY 208 E 10TH ST
AUSTIN
TX TEXAS
78701 US
THE BANK OF NEW YORK MELLON 500 GRANT STREET
27TH FLOOR
PITTSBURGH
PA PENNSYLVANIA
15258 US
  THE HUNTINGTON NATIONAL BANK 7 EASTON OVAL EA4E62
COLUMBUS
OH OHIO
43209 US
THE NORTHERN TRUST COMPANY 333 South Wabash Ave, 32nd Floor
Attn: Trade Securities Processing
CHICAGO
IL ILLINOIS
60603 US
  TRADESTATION SECURITIES, INC. 120 RIVERSIDE PLAZA
SUITE 1650
CHICAGO
IL ILLINOIS
60606 US
U.S. BANCORP INVESTMENTS, INC. 60 LIVINGSTON AVE
EP-MN-WN1B
ST. PAUL
MN MINNESOTA
55107-1419 US
  U.S. BANK N.A./ETF 1555 N RIVER CENTER DRIVE
MILWAUKEE
WI WISCONSIN
53212
U.S. BANK NATIONAL ASSOCIATION 1555 NORTH RIVERCENTER DRIVE, SUITE 302
SUITE 302
MILWAUKEE
WI WISCONSIN
53212 US
  UBS AG 480 WASHINGTON BLVD.
12TH FLOOR
JERSEY CITY
NJ NEW JERSEY
07310 US
UBS FINANCIAL SERVICES INC. 1000 HARBOR BOULEVARD
WEEHAWKEN
NJ NEW JERSEY
07086 US
  UBS SECURITIES LLC 677 WASHINGTON BLVD
STAMFORD
CT CONNECTICUT
06901 US
UMB BANK, NATIONAL ASSOCIATION 928 GRAND BLVD
KANSAS CITY
MO MISSOURI
64106 US
  VANGUARD MARKETING CORPORATION 100 VANGUARD BLVD
MALVERN
PA PENNSYLVANIA
19355 US
VELOCITY CLEARING, LLC 1301 Route 36
Suite 109 (Attn: Chris Felicetti)
HAZLET
NEW JERSEY
7730 US
  VELOX CLEARING LLC 2400 E. KATELLA AVENUE
SUITE 725A
ANAHEIM
CA CALIFORNIA
92806 US
VIRTU AMERICAS LLC ONE LIBERTY PLAZA, 165 BROADWAY
5TH FLOOR
NEW YORK
NY NEW YORK
10006 US
  VISION FINANCIAL MARKETS LLC 4 HIGH RIDGE PARK
SUITE 100
STAMFORD
CT CONNECTICUT
06905 US
WEDBUSH SECURITIES INC 1000 WILSHIRE BLVD
8TH FLOOR
LOS ANGELES
CA CALIFORNIA
90017 US
  WEDBUSH SECURITIES INC. 1000 WILSHIRE BLVD.
LOS ANGELES
CA CALIFORNIA
90017 US
WELLS FARGO BANK, N.A./SIG 733 MARQUETTE AVE 4TH FLOOR
MAC N9306-04D
MINNEAPOLIS
MN MINNESOTA
55402 US
  WELLS FARGO CLEARING SERVICES LLC 1 NORTH JEFFERSON
MAIL CODE: H0006-094
ST. LOUIS
MO MISSOURI
63103 US
WELLS FARGO SECURITIES, LLC 1525 WEST W T HARRIS BLVD
CHARLOTTE
NC NORTH CAROLINA
28262 US
  WILSON-DAVIS & CO., INC. 236 SOUTH MAIN STREET
SALT LAKE CITY
UT UTAH
84101 US

About Scilex Holding Company 

Scilex Holding Company, a majority-owned by Sorrento Therapeutics, Inc., is an innovative revenue-generating company focused on acquiring, developing, and commercializing non-opioid pain management products for the treatment of acute and chronic pain. Scilex is uncompromising in its focus to become the global pain management leader committed to social, environmental, economic, and ethical principles to responsibly develop pharmaceutical products to maximize quality of life. Results from the Phase III Pivotal Trial C.L.E.A.R Program for SEMDEXA™, its novel, non-opioid product for the treatment of lumbosacral radicular pain (sciatica), were announced in March 2022.  Scilex has applied for breakthrough therapy designation and expects to seek priority review for SEMDEXA™ for the treatment of sciatica.  Scilex targets indications with high unmet needs and large market opportunities with non-opioid therapies for the treatment of patients with moderate to severe pain.  Scilex launched its first commercial product in October 2018, in-licensed a commercial product in June 2022, and is developing its late-stage pipeline, which includes a pivotal Phase 3 candidate and one Phase 2 and one Phase 1 candidate.  Its commercial product, ZTlido® (lidocaine topical system) 1.8%, or ZTlido®, is a prescription lidocaine topical product approved by the U.S. Food and Drug Administration for the relief of pain associated with postherpetic neuralgia, which is a form of post-shingles nerve pain.  Scilex in-licensed the exclusive right to commercialize Gloperba® (colchicine USP) oral solution, an FDA-approved prophylactic treatment for painful gout flares in adults, in the U.S. Scilex is planning to commercialize Gloperba® in 2023 and is well-positioned to market and distribute the product. Scilex’s three product candidates are SP-102 (injectable dexamethasone sodium phosphate viscous gel product containing 10 mg dexamethasone), or SEMDEXA™, a Phase 3, novel, viscous gel formulation of a widely used corticosteroid for epidural injections to treat lumbosacral radicular pain, or sciatica, with FDA Fast Track status; SP-103 (lidocaine topical system) 5.4%, a Phase 2, triple-strength formulation of ZTlido®, for the treatment of low back pain, with FDA Fast Track status; and SP-104, 4.5 mg Delayed Burst Release Low Dose Naltrexone Hydrochloride (DBR-LDN) Capsule, for the treatment of chronic pain, fibromyalgia that has completed multiple Phase 1 trial programs and expected to initiate Phase 2 trials this year. For further information regarding the SP-102 Phase 3 efficacy trial, see NCT identifier NCT03372161 – Corticosteroid Lumbar Epidural Analgesia for Radiculopathy – Full Text View – ClinicalTrials.gov.

Scilex Holding Company is headquartered in Palo Alto, California, with operations in both Palo Alto and San Diego, California. For further information please visit www.scilexholding.com.

About Sorrento Therapeutics, Inc.

Sorrento is a clinical and commercial stage biopharmaceutical company developing new therapies to treat cancer, pain (non-opioid treatments), autoimmune disease and COVID-19. Sorrento’s multimodal, multipronged approach to fighting cancer is made possible by its extensive immuno-oncology platforms, including key assets such as Abivertinib, next-generation tyrosine kinase inhibitors (“TKIs”), fully human antibodies (“G-MAB™ library”), immuno-cellular therapies (“DAR-T™”), antibody-drug conjugates (“ADCs”), and oncolytic virus (“Seprehvec™”). Sorrento is also developing potential antiviral therapies and vaccines against coronaviruses, including STI-1558, COVI-MSC™; and diagnostic test solutions, including COVIMARK™.

Sorrento’s commitment to life-enhancing therapies for patients is also demonstrated by our effort to advance a TRPV1 agonist, non-opioid pain management small molecule, resiniferatoxin (“RTX”), and SP-102 (10 mg, dexamethasone sodium phosphate viscous gel) (SEMDEXA™), a novel, viscous gel formulation of a widely used corticosteroid for epidural injections to treat lumbosacral radicular pain, or sciatica, and to commercialize ZTlido® (lidocaine topical system) 1.8% for the treatment of postherpetic neuralgia (PHN). RTX has been cleared for a Phase II trial for intractable pain associated with cancer and a Phase II trial in osteoarthritis patients. Positive final results from the Phase III Pivotal Trial C.L.E.A.R. Program for SEMDEXA™, its novel, non-opioid product for the treatment of lumbosacral radicular pain (sciatica), were announced in March 2022. ZTlido® was approved by the FDA on February 28, 2018.

For more information visit www.sorrentotherapeutics.com.

Contacts:

For Scilex Holding Company

Jaisim Shah
Chief Executive Officer
Scilex Holding Company
960 San Antonio Road
Palo Alto, CA 94303
Office: (650) 516-4310

Email: [email protected]

Website:  www.sorrentotherapeutics.com and www.scilexholding.com

Investors and Media Contact:

Elizabeth Czerepak
Email: [email protected]
Website: www.sorrentotherapeutics.com

Sorrento® and the Sorrento logo are registered trademarks of Sorrento Therapeutics, Inc.

G-MAB™, DAR-T™, Seprehvec™, SOFUSA™, COVI-MSC™, COVIMARK™, Ovydso™ and Fujovee™ are trademarks of Sorrento Therapeutics, Inc.

SEMDEXA™ (SP-102) is a trademark owned by Semnur Pharmaceuticals, Inc., a wholly-owned subsidiary of Scilex Holding Company.  A proprietary name review by the FDA is planned.

ZTlido® is a registered trademark owned by Scilex Pharmaceuticals Inc., a wholly-owned subsidiary of Scilex Holding Company.

Gloperba® is an exclusive, transferable license to use the trademark by Scilex Holding Company.

All other trademarks are the property of their respective owners. 

© 2023 Sorrento Therapeutics, Inc. All Rights Reserved.