New book offers wisdom into Buddhist teachings that allow understanding of Dharma, lessen suffering and invite happiness

Venerable Mater Jing Guang releases ‘Living with Positive Energy: Let Love Flow’

MELBOURNE, Australia, Jan. 12, 2021 (GLOBE NEWSWIRE) — “Three days before the spring festival of 2015, I was invited to give a lecture on the Buddha’s teaching under the statue of the ThousandHand Guan Yin Bodhisattva (also known as Avalokiteśvara) in Yuanjue Temple in Hengyang, Hunan Province. In front of me, I saw many sad faces with affliction and confusion, I deeply felt their sorrow, and it saddened me. At that moment, I firmly believed in my heart that this trip back to China would carry a profound meaning with a sense of mission for the homeland,” Venerable Master Jing Guang states.

 

Translated by The Four Noble Truths Buddhist Society, English Translation Committee, the author’s book titled “Living with Positive Energy: Let Love Flow” (published by Balboa Press AU) gives people an illuminating guide to the Dharma, and through his comprehensive teaching and by reflecting on their lives, they can transcend their habitual response mode, to improve their relationships with others, to live a life that is free from suffering and fear, and to have a happy life with positive energy — let love flow.

 

The contents of this book are centered on the teachings of the Four Noble Truths. It relies on the right view of the Four Noble Truths: be kind to the relationships in the mundane world and to walk on the path of human-heavenly realm. After seeing clearly, one may enter the Dharma-stream. Relying on the teachings on the Four Noble Truths, one may be able to lessen the sufferings, further eradicate sufferings, and walk towards the path of liberation. Finally, one may rely on the teachings of the Dharma of the Four Noble Truths to reach the total cessation of dukkha, attain the liberation of mind, accomplish perfect enlightenment, and thus reach the ultimate perfection of Buddhahood.

 

“In today’s world, people have to deal with many pressures in their lives, especially in relationship. This book provides the insight from the Buddha’s teaching to address the root problems of relationships,” the author says. When asked what he wants readers to take away from the book, he answers, “To clearly understand the true fact of life, all phenomena arising and ceasing simultaneously, there is nothing we can hold onto, so that we can let go of our cravings and stop projecting our own needs to people around us.” For more details about the book, please visit https://www.balboapress.com/en-au/bookstore/bookdetails/793694-living-with-positive-energy

 

“Living with Positive Energy: Let Love Flow”

By Venerable Master Jing Guang

Softcover | 5.5 x 8.5in | 164 pages | ISBN 9781504322508

E-Book | 164 pages | ISBN 9781504322683

Available at Amazon and Barnes & Noble

 

About the Author

Venerable Master Jing Guang graduated with a philosophy major from the National Taiwan University. He was the founder of The Original Buddhism Ming-He Lecture Hall, and currently serves as the guidance master of The Four Noble Truths Buddhist Society. His footprints covered all over Taiwan, mainland China, Singapore, Malaysia, Silicon Valley of the United States, Australia and others. More than 5,000 people participated and benefited from the Venerable’s teaching.

Balboa Press Australia is a division of Hay House, Inc., a leading provider in publishing products that specialise in self-help and the mind, body and spirit genre. Through an alliance with the worldwide self-publishing leader Author Solutions, LLC, authors benefit from the leadership of Hay House Publishing and the speed-to-market advantages of the Author Solutions self-publishing model. For more information or to start publishing today, visit balboapress.com.au/ or call 1-800-844-925.

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Marketing Services
Balboa Press AU
1-800-844-925
[email protected]

The last remnants of humanity fight for survival and an end to undead horrors

David Stanley announces the release of ‘Ironbark Creek’

BATHURST, Australia, Jan. 12, 2021 (GLOBE NEWSWIRE) — David Stanley has been interested in zombie related things for a while. But he also wanted to twist the story by having Indigenous people be immune to becoming zombies. The idea was settled before COVID-19 came along, but this added fire to his desire to write this story. And now, he releases, “Ironbark Creek” (published by Balboa Press AU), a story about the importance of home and family, Indigenous empowerment as well as resiliency in the face of life’s’ challenges.

 

The world has turned. COVID-25 has created havoc and Cathy, an Indigenous woman knows the key to survival is finding and keeping their home safe. ‘Ambos’ (their word for the ‘turned’) ravage the country while Cathy and Jack fight to build a community, all the while struggling to understand what lies beyond the trench that surrounds Ironbark Creek.

 

“It is topical with the virus called COVID-25. It is about zombies. It addresses racial issues and supports female and Indigenous empowerment,” Stanley says. “It addresses two key issues for today: A global pandemic and racial tensions in line with Black Lives Matter movement.” 

 

When asked what he wants readers to take away from his writing of this book, Stanley replies, “A rollicking, gripping and enjoyable tail of resilience and the power of community and family over adversity.” For more details about this book, please visit https://www.balboapress.com/en-au/bookstore/bookdetails/817519-ironbark-creek

 

“Ironbark Creek”

By David Stanley

Softcover | 7.5 x 9.25in | 280 pages | ISBN 9781504323482

E-Book | 280 pages | ISBN 9781504323499

Available at Amazon and Barnes & Noble

 

About the Author

David Stanley has been a nurse and midwife for over 40 years. He has taught and practiced nursing in rural and remote parts of Australia and internationally. He has an extensive academic publication history, although this is his first foray into action and adventure writing.

 

Balboa Press Australia is a division of Hay House, Inc., a leading provider in publishing products that specialise in self-help and the mind, body and spirit genre. Through an alliance with the worldwide self-publishing leader Author Solutions, LLC, authors benefit from the leadership of Hay House Publishing and the speed-to-market advantages of the Author Solutions self-publishing model. For more information or to start publishing today, visit balboapress.com.au/ or call 1-800-844-925.

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Marketing Services
Balboa Press AU
1-800-844-925
[email protected]

Two-act play explores the journey of Jack as he longs for acceptance and finding joy and fulfilment in a small town beset with troubles

Jane V King releases ‘The Pier End: A Play in Two Acts’

CARDIFF, Wales, Jan. 12, 2021 (GLOBE NEWSWIRE) — Jane V King is inspired by the natural world, finding piers as spiritual places where problems can be thought through and solved. Her book, “The Pier End: A Play in Two Acts” (published by Balboa Press) was written in response to a request for a new community play that could celebrate local talent. It has been compared to a medieval mystery play. The intention is to bring people together in creative celebration to entertain local audiences.

 

Set at “the other end of the pier” on the edge of a small town beset with troubles, the play is about Jack, an orphan, although both of his parents are still alive and are in unknown locations. He acts as a mentor and supporter in his community. But when he is on his own, he has dark thoughts about his lack of kinship. He tries to fill the void by dating three girls simultaneously, and he dislikes himself for his faithlessness. He interacts with the local councilor who represents the problems of the sad little town and he was overjoyed to find his mother after so many years apart.

 

“This two act play explores timeless, universal themes such as the power of love and family, but is firmly in the present to relate to the modern day concerns of the cast and audience. It allows local talents to be incorporated, with original songs they can use and interpret in their own way,” King says.

 

King finds the end of a pier a mystical place where “earth, sea, and sky all meet.” She hopes that “The Pier End: A Play in Two Acts” will provide readers an uplifted feeling that they can go and meditate.  For more details about the book, please visit https://www.balboapress.com/en/bookstore/bookdetails/816346-the-pier-end

 

“The Pier End: A Play in Two Acts”

By Jane V King

Softcover | 5.5 x 8.5in | 48 pages | ISBN 9781982258108

E-Book | 48 pages | ISBN 9781982258115

Available at Amazon and Barnes & Noble

 

About the Author

Jane V King has taught extensively across several subjects, including Science and Drama. She graduated from the University of Birmingham with an honors degree in biological sciences. She has run countless drama projects, including being principal of a branch of the world’s largest after school organization for children. She is married, is a mother and grandmother, and lives in the beautiful Vale of Glamorgan in Wales.

Balboa Press, a division of Hay House, Inc. – a leading provider in publishing products that specialize in self-help and the mind, body, and spirit genres. Through an alliance with the worldwide self-publishing leader Author Solutions, LLC, authors benefit from the leadership of Hay House Publishing and the speed-to-market advantages of the self-publishing model. For more information, visit balboapress.com. To start publishing your book with Balboa Press, call 844-682-1282 today.

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Balboa Press
844-682-1282
[email protected]

Clean Power Provides Update on PowerTap’s California Hydrogen Fueling Station launch in 2021:

In-line with California Governor Newsom’s Proposed Stimulus Plan

VANCOUVER, British Columbia, Jan. 12, 2021 (GLOBE NEWSWIRE) — Clean Power Capital Corp. (CSE: MOVE)(FWB: 2K6)(OTC: MOTNF) (“Clean Power” or the “Company” or “MOVE”). Clean Power is encouraged by and applauds the announcement by California Governor Newsom for his proposal to earmark $1.5 billion for companies to invest in the construction and maintenance of charging and hydrogen fueling infrastructure as part of a $4.5 billion stimulus proposal for the 2021 state budget1.

Governor Newsom’s announcement is aligned with PowerTap’s preparation of its hydrogen station permitting as it prepares for its rollout of initial hydrogen fueling stations in the second half of 2021. The PowerTap hydrogen stations will be completed and installed in accordance with the California Governor’s Office of Business and Economic Development (GO-Biz) permitting guidebook2.

As announced in Clean Power’s December 15, 2020 press release, PowerTap also plans to participate in the California Low Carbon Fuel Standard (“LCFS”) Carbon Credit program, which provides PowerTap an opportunity to generate revenue from the sale of its earned LCFS credits on an on-going basis on the emission trading markets, even prior to generating any revenue from the sale of hydrogen.

Raghu Kilambi, CEO of PowerTap Hydrogen Fueling Corp. said, “PowerTap plans to launch hydrogen fueling station rollout in the second half of 2021 and will be announcing initial rollout partners in the near term. California’s announced stimulus plans for hydrogen infrastructure supports PowerTap’s aggressive rollout strategy. In addition, with the incoming Biden Administration and the Democrats gaining control of the United States Senate with the win of control of the Senate with two key Senate runoff elections in the State of Georgia, PowerTap is optimistic that the US federal government will introduce new green initiatives that will include incentives and funding for the hydrogen infrastructure space.”

About PowerTap

The Company invested in PowerTap on October 27, 2020 (see the Company’s news release on October 28, 2020). PowerTap is leading the charge to build out cost-effective hydrogen fueling infrastructure through its environmentally friendly intellectual property, product design for the modularized and lowest tier production cost of hydrogen, and launch plan.  PowerTap technology-based hydrogen fueling stations are located in private enterprises and public stations (near LAX airport) in California, Texas, Massachusetts, and Maryland.  Additional information about PowerTap and the Hydrogen Industry may be found at its website at http://www.powertapfuels.com

ABOUT CLEAN POWER CAPITAL CORP.

Clean Power is an investment company, that specializes in investing into private and public companies opportunistically that may be engaged in a variety of industries, with a current focus in the health and renewable energy industries. In particular, the investment mandate is focused on high return investment opportunities, the ability to achieve a reasonable rate of capital appreciation and to seek liquidity in our investments. A copy of Clean Power’s amended and restated investment policy may be found under the Company’s profile at www.sedar.com.

ON BEHALF OF THE CLEAN POWER CAPITAL CORP. BOARD OF DIRECTORS

“Joel Dumaresq”

Joel Dumaresq CEO
+1 (604) 687-2038
[email protected]

Learn more about Clean Power by visiting our website at: https://cleanpower.capital/

THE CSE HAS NOT REVIEWED AND DOES NOT ACCEPT RESPONSIBILITY FOR THE ACCURACY OR ADEQUACY OF THIS RELEASE.

Notice Regarding Forward Looking Information:

This press release contains “forward-looking statements” or “forward-looking information” (collectively referred to herein as “forward-looking statements”) within the meaning of applicable securities legislation. Such forward-looking statements include, without limitation, forecasts, estimates, expectations and objectives for future operations that are subject to a number of assumptions, risks and uncertainties, many of which are beyond the control of Clean Power. Some assumptions include, without limitation, the development of hydrogen powered vehicles by vehicle makers, the adoption of hydrogen powered vehicles by the market, legislation and regulations favoring the use of hydrogen as an alternative energy source, the Company’s ability to build out its planned hydrogen fueling station network, and the Company’s ability to raise sufficient funds to fund its business plan. Forward-looking statements are statements that are not historical facts and are generally, but not always, identified by the words “expects”, “plans”, “anticipates”, “believes”, “intends”, “estimates”, “projects”, “potential” and similar expressions, or that events or conditions “will”, “would”, “may”, “could” or “should” occur or be achieved. This press release contains forward-looking statements pertaining to, among other things, the timing and ability of the Company to complete any potential investments or acquisitions, if at all, and the timing thereof. Forward-looking information is based on current expectations, estimates and projections that involve a number of risks, which could cause actual results to vary and, in some instances, to differ materially from those anticipated by the Company and described in the forward-looking information contained in this press release.

Although the Company believes that the material factors, expectations and assumptions expressed in such forward- looking statements are reasonable based on information available to it on the date such statements were made, no assurances can be given as to future results, levels of activity and achievements and such statements are not guarantees of future performance.

The forward-looking information contained in this release is expressly qualified by the foregoing cautionary statements and is made as of the date of this release. Except as may be required by applicable securities laws, the Company does not undertake any obligation to publicly update or revise any forward- looking information to reflect events or circumstances after the date of this release or to reflect the occurrence of unanticipated events, whether as a result of new information, future events or results, or otherwise.

1 (https://www.cnbc.com/2021/01/06/newsom-plan-includes-1point5-billion-to-boost-electric-hydrogen-vehicles.html)
2 https://cdn.businessportal.ca.gov/wp-content/uploads/2020/09/GO-Biz_Hydrogen-Station-Permitting-Guidebook_Sept-2020.pdf



Adagene Announces Milestone of CAR-T Collaboration with the National Heart, Lung, and Blood Institute at the National Institutes of Health

– Collaboration with Richard Childs, M.D., yields potential first-ever antibodies targeting human endogenous retrovirus associated with renal cell carcinoma

SAN FRANCISCO, Calif. and SUZHOU, China, Jan. 12, 2021 (GLOBE NEWSWIRE) — Adagene, Inc., a platform-driven, clinical-stage biopharmaceutical company with precision antibody engineering, discovery and development capabilities, today announced the successful completion of its component of the collaboration with Richard Childs, M.D., Chief of the Laboratory of Transplantation Immunotherapy at the National Heart, Lung, and Blood Institute, part of the National Institutes of Health (NIH). As a result of the collaboration, Adagene discovered antibodies that Dr. Child’s laboratory has turned into a CAR-T cell therapy candidate for the potential treatment of renal cell carcinoma, the most common type of kidney cancer in adults, according to Frost & Sullivan.

Human endogenous retroviruses (HERVs), remnants of ancient germ-line infections with exogenous retroviruses, are estimated to comprise up to 8% of the human genome. A growing number of HERV genes and proteins have been found to be expressed in different cancers, and they might represent new targets for tumor immunotherapy.

“The novel antibodies that were co-discovered and tested by Adagene and the National Heart, Lung, and Blood Institute have enabled us to potentially develop the first CAR-T cell therapy candidate targeting a human endogenous retrovirus expressed in the majority of clear cell kidney tumors,” said Dr. Childs. “This is an encouraging development that builds on decades of research in our quest to find ways to adapt and enhance immune cells to target and kill even the most aggressive cancers. I look forward to the evaluation and hopefully the development of this novel CAR-T cell and other antibody-based therapies in clinical trials.”

The NIH will lead and be responsible for the manufacturing and clinical development of the CAR-T cell therapy candidate.

“Adagene is honored to have worked with Dr. Childs and his laboratory on this novel family of HERV as a potential target for tumor immunotherapy,” said Peter Luo, Ph.D., Co-founder, Chief Executive Officer and Chairman of Adagene. “Using our NEObody™ technology, we identified novel antibodies against HERV expressed targets in renal cell carcinoma, which to our knowledge has never before been accomplished. We look forward to the advancement of the first-in-class CAR-T cell therapy Dr. Childs’ laboratory has pioneered based on antibodies discovered at Adagene. In the meantime, Adagene continues to progress its pipeline of programs developed with NEObody™ and SAFEbody™ technologies, to address unmet medical needs.”

NEObody™ is part of Adagene’s Dynamic Precision Library (DPL) platform, which combines computational biology and synthetic biology to enable the selection of antibody candidates with novel epitopes, robust CMC profiles and desired safety and efficacy attributes for downstream development.

About Adagene

Adagene, Inc. is a platform-driven, clinical-stage biopharmaceutical company committed to transforming the discovery and development of novel antibody-based cancer immunotherapies. Adagene combines computational biology and artificial intelligence to design novel antibodies that address unmet patient needs. Its proprietary pipeline is comprised of novel immunotherapy programs. Adagene has forged strategic collaborations with reputable global partners that leverage its technology in multiple approaches at the vanguard of science.

Forward Looking Statements

This article contains forward-looking statements that reflect our current expectations and views of future events, including but not limited to those regarding the therapeutic potential of and potential clinical development and commercialization plans for Adagene’s pipeline candidates, its strategic and financial plans and expectations, as well as financial projections.

In some cases, forward-looking statements can be identified by words or phrases such as “may,” “will,” “expect,” “anticipate,” “aim,” “estimate,” “intend,” “plan,” “believe,” “is/are likely to,” “potential,” “continue” or other similar expressions. We have based these forward-looking statements largely on our current expectations and projections about future events that we believe may affect our financial condition, results of operations, business strategy and financial needs. These forward-looking statements include statements relating to: our goals and strategies; our future business development, financial conditions and results of operations; results of our clinical trials and preclinical studies; the expected collaboration between NIH and us; our expectations regarding our relationships with our business partners and our other stakeholders; competition in our industry; and relevant government policies and regulations relating to our industry.

Although we believe that our expectations expressed in these forward-looking statements are reasonable, our expectations may later be found to be incorrect. Our actual results could be materially different from our expectations. Known and unknown risks, uncertainties and other factors may cause our actual results, performance or achievements to be materially different from those expressed or implied by the forward-looking statements. Management’s expectations and, therefore, any forward-looking statements in this presentation could also be affected by risks and uncertainties relating to a number of other factors, many of which are beyond Adagene’s control. All information in this article is as of the date hereof, and Adagene disclaims any obligation to update or revise such information unless required by law.

Investors Contact

Raymond Tam
Adagene
86-8777-3626
[email protected]
[email protected]

Media Contact

Annie Starr
6 Degrees
973-768-2170
[email protected] 



Innovent Announces NMPA Acceptance of a Supplemental New Drug Application for Sintilimab as Second-Line Therapy for Squamous Non-Small Cell Lung Cancer

PR Newswire

SAN FRANCISCO and SUZHOU, China, Jan. 11, 2021 /PRNewswire/ — Innovent Biologics, Inc. (“Innovent”, HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high-quality medicines for the treatment of cancer, metabolic, autoimmune and other major diseases, today announced with Eli Lilly and Company (“Lilly”, NYSE: LLY) that the National Medical Products Administration (NMPA) of China has accepted the supplemental New Drug Application (sNDA) for TYVYT® (sintilimab injection) as second-line therapy for squamous non-small cell lung cancer (sqNSCLC). The application is the third sNDA for TYVYT® (sintilimab injection) in NSCLC.

This sNDA was based on a randomized, open-label, Phase 3 clinical trial (ORIENT-3)—evaluating TYVYT® (sintilimab injection) as second-line therapy for patients with advanced or recurrent sqNSCLC whose cancer had progressed on first-line platinum-based chemotherapy. Based on the final analysis in the pre-specified full analysis set, TYVYT® demonstrated a statistically significant improvement in overall survival (OS) compared with docetaxel, which met the pre-specified superiority criteria. The progression-free survival (PFS) and objective response rate (ORR) were also significantly improved. The safety profile is consistent with previously reported sintilimab studies, and no new safety signals were identified. Detailed data will be released in an upcoming international academic conference or journal.

The principal investigator of ORIENT-3, Professor Yuankai Shi, Associate Dean of Cancer Hospital, Chinese Academy of Medical Sciences, stated: “Lung cancer is the leading cause of cancer death globally, of which NSCLC accounts for 80% to 85%. In the past few decades, drug development of NSCLC has mainly focused on nonsquamous NSCLC, while drug development of squamous NSCLC has been slower due to its unique epidemiological, histopathological and molecular characteristics. In China, the options for second-line immunotherapy are even more limited. The ORIENT-3 study confirmed that the anti-PD-1 monoclonal antibody sintilimab significantly improved OS for the second-line treatment of squamous NSCLC patients, which is of great clinical value. We hope that the positive results of ORIENT-3 can potentially help more squamous NSCLC patients.”

“TYVYT® (sintilimab injection) is the first anti-PD-1 monoclonal antibody included in the New Catalogue of the National Reimbursement Drug List,” said Dr. Hui Zhou, Vice President of Medical Science and Strategy Oncology of Innovent. “In August 2020, the NMPA accepted a new indication application for TYVYT® (sintilimab injection) in combination with chemotherapy for first-line treatment of squamous NSCLC. In ORIENT-3 study, sintilimab as second-line monotherapy demonstrated a significantly improved survival benefit for patients with advanced squamous NSCLC, and we look forward to the approval of this indication, to potentially help more patients with this type of lung cancer.”

“We are excited about these results, showing TYVYT® (sintilimab injection) significantly improved overall survival in this patient population. This study underscores the joint commitment from Lilly and Innovent to provide innovative treatment options to patients with lung cancer,” said Dr. Wang Li, Senior Vice President of Lilly China and Head of Lilly China Drug Development and Medical Affairs. “We would like to thank the patients, the investigators, the clinical trial centers and our colleagues from Innovent that are involved in the study. We look forward to working together to potentially bring this new treatment option to patients in China with squamous NSCLC.”

About ORIENT-3 Trial

ORIENT-3 is a randomized, open-label, multi-center, Phase 3 clinical trial in China to evaluate the efficacy and safety of TYVYT® (sintilimab injection) as second-line therapy for advanced or metastatic sqNSCLC (ClinicalTrials.gov, NCT 03150875). The primary endpoint is overall survival (OS). The secondary endpoints include progression-free survival (PFS) assessed by investigators based on RECIST v1.1, objective response rate (ORR) and safety profile.

A total of 290 patients were enrolled in ORIENT-3 and randomized in a 1:1 ratio to receive either TYVYT® (sintilimab injection) 200mg or docetaxel every three weeks. The patients received treatment until radiographic disease progression, unacceptable toxicity or any other conditions that require treatment discontinuation.

About Squamous NSCLC

Lung cancer is a malignancy with the highest morbidity and mortality in China. NSCLC accounts for about 80 to 85 percent of lung cancer. Approximately 70 percent of people with NSCLC have locally advanced or metastatic NSCLC at initial diagnosis, rendering many of those patients with no chance of radical resection. Meanwhile, even after radical surgery, patients still have a high chance of recurrence and eventually die from disease progression. About 30 percent of people with NSCLC in China have tumors of the squamous subtype and there are limited second-line immunotherapies for these patients. In China, there remains a huge unmet medical need.

About TYVYT® (Sintilimab Injection)

TYVYT® (sintilimab injection), an innovative drug with global quality standards jointly developed in China by Innovent and Eli Lilly and Company, has been granted marketing approval by the NMPA for the treatment of relapsed or refractory classic Hodgkin’s lymphoma after two lines or later of systemic chemotherapy, and is included in the 2019 Guidelines of Chinese Society of Clinical Oncology for Lymphoid Malignancies. TYVYT® was included in the National Reimbursement Drug List (NRDL) in 2019 as the historically first PD-1 inhibitor entering in NRDL and the only PD-1 included in the list in that year.

In April 2020, the NMPA accepted the sNDA for TYVYT® (sintilimab injection) in combination with ALIMTA® (pemetrexed) and platinum chemotherapy as first-line therapy for the treatment of patients with non-squamous non-small cell lung cancer (NSCLC). In May 2020, TYVYT® (sintilimab injection) monotherapy met the primary endpoint of overall survival in the Phase 2 ORIENT-2 study as second-line therapy in patients with advanced or metastatic esophageal squamous cell carcinoma. In August 2020, the NMPA accepted the sNDA for TYVYT® in combination with GEMZAR® (gemcitabine for injection) and platinum chemotherapy as first-line therapy in squamous NSCLC. In September 2020, TYVYT® (sintilimab injection) in combination with BYVASDA® (bevacizumab biosimilar injection) as a first-line treatment in advanced hepatocellular carcinoma met the predefined primary endpoints of overall survival and progression-free survival in an interim analysis of the Phase 3 ORIENT-32 study. In January 2021, the NMPA accepted the sNDA for TYVYT® as second-line therapy for sqNSCLC.

TYVYT® (sintilimab injection), is a type of immunoglobulin G4 monoclonal antibody, which binds to PD-1 molecules on the surface of T-cells, block the PD-1 / PD-Ligand 1 (PD-L1) pathway and reactivate T-cells to kill cancer cells. Innovent is currently conducting more than 20 clinical studies with TYVYT® (sintilimab injection) to evaluate its safety and efficacy in a wide variety of cancer indications, including more than 10 registrational or pivotal clinical trials. Meanwhile, Innovent is conducting clinical research studies on TYVYT® (sintilimab injection) worldwide.

About Innovent

Inspired by the spirit of “Start with Integrity, Succeed through Action,” Innovent’s mission is to develop, manufacture and commercialize high-quality biopharmaceutical products that are affordable to ordinary people. Established in 2011, Innovent is committed to developing, manufacturing and commercializing high quality innovative medicines for the treatment of cancer, autoimmune, metabolic and other major diseases. On October 31, 2018, Innovent was listed on the Main Board of the Stock Exchange of Hong Kong Limited with the stock code: 01801.HK.

Since its inception, Innovent has developed a fully integrated multi-functional platform which includes R&D, CMC (Chemistry, Manufacturing, and Controls), clinical development and commercialization capabilities. Leveraging the platform, the company has built a robust pipeline of 23 valuable assets in the fields of cancer, metabolic, autoimmune diseases and other major therapeutic areas, with 4 products – TYVYT® (sintilimab injection), BYVASDA® (bevacizumab biosimilar injection) , SULINNO® (adalimumab biosimilar injection) and HALPRYZA® (rituximab biosimilar injection) – officially approved for marketing in China, four assets in Phase 3 or pivotal clinical trials, and additional 15 molecules in clinical trials. TYVYT® (sintilimab injection) is the first PD-1 inhibitor included in the NRDL.

Innovent has built an international team of advanced talents in high-end biological drug development and commercialization, including many overseas experts. The company has also entered into strategic collaborations with Eli Lilly and Company, Adimab, Incyte, MD Anderson Cancer Center, Hanmi and other international partners. Innovent strives to work with all relevant parties to help advance China’s biopharmaceutical industry, improve drug availability to ordinary people and enhance the quality of the patients’ lives.  For more information, please visit: www.innoventbio.com.

About Eli Lilly and Company

Lilly is a global healthcare leader that unites caring with discovery to create medicines to make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at www.lilly.com and lilly.com/newsroom.

About Innovent Biologics’ strategic collaboration with Eli Lilly and Company

Innovent entered into a strategic collaboration with Lilly focused on biological medicine in March 2015 – a groundbreaking partnership between a Chinese pharmaceutical company and a multinational pharmaceutical company. Under the agreement, Innovent and Lilly are co-developing and commercializing oncology medicines, including TYVYT® (sintilimab injection) in China. In October 2015, the two companies announced the extension of their existing collaboration to include co-development of three additional oncology antibodies targeting oncology indications. In August 2019, Innovent further entered a licensing agreement with Lilly to develop and commercialize a potentially global best-in-class diabetes medicine in China. Its collaboration with Lilly indicates that Innovent has established a comprehensive level of cooperation between China’s innovative pharmaceuticals sector and the international pharmaceuticals sector in fields such as R&D, CMC, clinical development and commercialization. In August 2020,Lilly and Innovent announced a global expansion of their strategic alliance for TYVYT® (sintilimab injection), whereby Lilly obtained an exclusive license for TYVYT® (sintilimab injection) for geographies outside of China and plans to pursue registration of TYVYT® (sintilimab injection) in the U.S. and other markets.

Note:

TYVYT® (sintilimab injection) is not an approved product in the United States.

BYVASDA® (bevacizumab biosimilar injection) is not an approved product in the United States.

SULINNO® (adalimumab biosimilar injection) is not an approved product in the United States.

HALPRYZA® (rituximab biosimilar injection)
is not an approved product in the United States.

TYVYT® (sintilimab injection, Innovent)
BYVASDA® (bevacizumab biosimilar injection, Innovent)
SULINNO® (adalimumab biosimilar injection, Innovent)
HALPRYZA® (rituximab biosimilar injection, Innovent)

ALIMTA® and GEMZAR® are trademarks owned by or licensed to Eli Lilly and Company, its subsidiaries, or affiliates.

Disclaimer:

1. This indication is still under clinical trial, which hasn’t been approved in China.

2. Innovent does not recommend any off-label usage.

3. For medical and healthcare professionals only.

Cision View original content:http://www.prnewswire.com/news-releases/innovent-announces-nmpa-acceptance-of-a-supplemental-new-drug-application-for-sintilimab-as-second-line-therapy-for-squamous-non-small-cell-lung-cancer-301205888.html

SOURCE Innovent Biologics

SHAREHOLDER ALERT: WeissLaw LLP Reminds ZAGG, PS, TCF, and SNCA Shareholders About Its Ongoing Investigations

PR Newswire

NEW YORK, Jan. 11, 2021 /PRNewswire/ —


If you own shares in any of the companies listed above and
would like to discuss our investigations or have any questions concerning
this notice or your rights or interests, please contact:


Joshua Rubin, Esq.

WeissLaw LLP
1500 Broadway, 16th Floor
New York, NY  10036
(212) 682-3025
(888) 593-4771
[email protected]

ZAGG Inc. (NASDAQ: ZAGG)

WeissLaw LLP is investigating possible breaches of fiduciary duty and other violations of law by the board of directors of ZAGG Inc. (NASDAQ: ZAGG) in connection with the proposed acquisition of the company by a group led by Evercel, Inc.  Under the terms of the acquisition agreement, the company’s shareholders will only receive $4.20 per share in cash and a contingent amount of up to $0.25 for each share of ZAGG common stock that they hold.  If you own ZAGG shares and wish to discuss this investigation or your rights, please call us at one of the numbers listed above or visit our website: https://www.weisslawllp.com/zagg/

Pluralsight, Inc. (NASDAQ: PS)

WeissLaw LLP is investigating possible breaches of fiduciary duty and other violations of law by the board of directors of Pluralsight, Inc. (NASDAQ: PS) in connection with the proposed acquisition of the company by Vista Equity Partners.  Under the terms of the acquisition agreement, PS shareholders will receive $20.26 per share in cash for each share of PS common stock that they hold.  If you own PS shares and wish to discuss this investigation or your rights, please call us at one of the numbers listed above or visit our website:  https://weisslawllp.com/news/ps/

TCF Financial Corporation (NASDAQ: TCF) 

WeissLaw LLP is investigating possible breaches of fiduciary duty and other violations of law by the board of directors of TCF Financial Corporation (NASDAQ: TCF) in connection with the proposed stock-for-stock merger of the company with Huntington Bancshares Incorporated (“Huntington“).  Under the terms of the merger agreement, TCF shareholders will receive 3.0028 shares of Huntington common stock for each share of TCF that they hold, representing implied per-share merger consideration of $43.33 based upon Huntington’sJanuary 8, 2021 closing price of $14.43.  If you own TCF shares and wish to discuss this investigation or your rights, please call us at one of the numbers listed above or visit our website: https://www.weisslawllp.com/tcf/  

Seneca Biopharma, Inc. (NASDAQ: SNCA)

WeissLaw LLP is investigating possible breaches of fiduciary duty and other violations of law by the board of directors of Seneca Biopharma, Inc. (NASDAQ: SNCA) in connection with the company’s proposed merger with Leading BioSciences, Inc. (“LBS”).  Under the terms of the agreement, LBS shareholders will receive shares of SNCA, resulting in LBS stockholders owning a majority of the combined company, with SNCA shareholders owning just 26.2% of the surviving combined entity.  If you own SNCA shares and wish to discuss this investigation or your rights, please call us at one of the numbers listed above or visit our website: https://www.weisslawllp.com/snca/  

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SOURCE WeissLaw LLP

SHAREHOLDER ALERT: WeissLaw LLP Reminds MGLN, SMTX, and FLIR, Shareholders About Its Ongoing Investigations

PR Newswire

NEW YORK, Jan. 11, 2021 /PRNewswire/ —


If you own shares in any of the companies listed above and
would like to discuss our investigations or have any questions concerning
this notice or your rights or interests, please contact:


Joshua Rubin, Esq.

WeissLaw LLP
1500 Broadway, 16th Floor
New York, NY  10036
(212) 682-3025
(888) 593-4771
[email protected]

Magellan Health, Inc.
(NASDAQ: MGLN)

WeissLaw LLP is investigating possible breaches of fiduciary duty and other violations of law by the board of directors of Magellan Health, Inc. (“Magellan” or the “Company”) (NASDAQ: MGLN) in connection with the proposed acquisition of the Company by Centene Corporation (NYSE: CNC).  Under the terms of the agreement, the Company’s shareholders will receive $95 in cash for each share of Magellan common stock that they own.  If you own MGLN shares and wish to discuss this investigation or your rights, please call us at one of the numbers listed above or visit our website: https://www.weisslawllp.com/mgln/

SMTC Corporation
 (NASDAQ: SMTX)

WeissLaw LLP is investigating possible breaches of fiduciary duty and other violations of law by the board of directors of SMTC Corporation (“SMTX” or the “Company”) (NASDAQ: SMTX) in connection with the proposed acquisition of the Company by an affiliate of H.I.G. Capital.  Under the terms of the merger agreement, the Company’s shareholders will receive $6.044 in cash for each share of SMTX common stock that they own.   If you own SMTX shares and wish to discuss this investigation or your rights, please call us at one of the numbers listed above or visit our website:  https://weisslawllp.com/news/smtx/

FLIR Systems, Inc.
 (NASDAQ: FLIR) 

WeissLaw LLP is investigating possible breaches of fiduciary duty and other violations of law by the board of directors of FLIR Systems, Inc. (“FLIR” or the “Company”) (NASDAQ: FLIR) in connection with the proposed acquisition of the Company by Teledyne Technologies Incorporated (“Teledyne”) (NYSE: TDY).  Under the terms of the merger agreement, Teledyne will acquire FLIR in a mixed cash-and-stock transaction, pursuant to which FLIR shareholders will receive $28.00 in cash and 0.0718 shares of Teledyne common stock for each FLIR share that they own, representing implied per-share merger consideration of approximately $54.45 based upon Teledyne’s January 8, 2021 closing price of $368.33.  If you own FLIR shares and wish to discuss this investigation or your rights, please call us at one of the numbers listed above or visit our website: https://www.weisslawllp.com/flir/  

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SOURCE WeissLaw LLP

ZTO Express held 2020 Year-end Network Partner Convention

PR Newswire

SHANGHAI, Jan. 11, 2021 /PRNewswire/ — On January 12, 2021 local time, ZTO Express (Cayman) Inc. (NYSE: ZTO; HKEX: 2057) (“ZTO” or the “Company”), a leading and fast-growing express delivery company in China, held its 2020 year-end network partner convention in Qingpu, Shanghai, where ZTO’s headquarter is located.

The participating management of the Company reviewed and summarized the achievements in 2020. Over the past year, even though the global economy was hit by the epidemic and the competition in the industry has intensified, the Company still stood together with nearly 30,000 network partners to continuously promote diversified outlet empowerment measures, which maintained the stability of the network. ZTO rounded off this year with the parcel volume growing faster than the industry, the steadily increased market share, and the continuously excellent service quality and customer satisfaction. Throughout 2020, the Company delivered 17 billion parcels, a year-over-year growth of 40.3%, further expanded its market share, and ranked first in terms of parcel volume among the peers.

In 2021, ZTO will stay committed to the mission and empower the whole network to ensure the orderly establishment of the ecosystem, the further expansion of the market share, the steady growth of the network’s overall profitability, the security of pickup-delivery, operation and information across the whole network, and the leading position of the service quality in the industry to accelerate the development in the changing situations.

About ZTO Express (Cayman) Inc.

ZTO Express (Cayman) Inc. (NYSE: ZTO and HKEX: 2057) (“ZTO” or the “Company”) is a leading and fast-growing express delivery company in China. ZTO provides express delivery service as well as other value-added logistics services through its extensive and reliable nationwide network coverage in China.

ZTO operates a highly scalable network partner model, which the Company believes is best suited to support the significant growth of e-commerce in China. The Company leverages its network partners to provide pickup and last-mile delivery services, while controlling the mission-critical line-haul transportation and sorting network within the express delivery service value chain.

For more information, please visit http://zto.investorroom.com.

Safe Harbor Statement

This announcement contains forward-looking statements. These statements are made under the “safe harbor” provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as “will”, “expect”, “anticipate”, “estimate”, “believe”, “going forward”, “ought to”, “may”, “seek”, “intend”, “plan”, “projection”, “could”, “vision”, “goals”, “aim”, “aspire”, “objective”, “target”, “schedules”, “outlook” and similar statements. ZTO Express may make written or oral forward-looking statements in its periodic reports to the SEC, in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Statements that are not historical facts, including statements about ZTO Express’s beliefs and expectations, are forward-looking statements. Forward-looking statements involve inherent risks and uncertainties. A number of factors could cause actual results to differ materially from those contained in any forward-looking statement. Further information regarding these and other risks is included in ZTO Express’s filings with the SEC and HKEX. All information provided in this press release and in the attachments is as of the date of this press release, and ZTO Express undertakes no obligation to update any forward-looking statement, except as required under applicable law.

For investor inquiries, please contact:

Investor Relations

E-mail: [email protected]
Phone: +86 21 5980 4508

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SOURCE ZTO Express (Cayman) Inc.

Global Partner Acquisition Corp II Announces Pricing of $275 Million Upsized Initial Public Offering

New York, NY, Jan. 11, 2021 (GLOBE NEWSWIRE) — Global Partner Acquisition Corp II (“GPAC II” or the “Company”), a blank check company formed for the purpose of entering into a merger, share exchange, asset acquisition, share purchase, reorganization or similar business combination with one or more businesses, today announced the pricing of its initial public offering of 27,500,000 units at a price of $10.00 per unit. Although the Company may pursue a business combination target in any business, industry or sector, the Company intends to focus its efforts on completing a business combination with a company in one of the following sectors: consumer; food; branded products; e-commerce and retail disruptors; and the consumerization of healthcare, as well as certain service sectors and the technology driving changes across these sectors and related industries.

The units will be listed on the Nasdaq Capital Market (“Nasdaq”) and trade under the ticker symbol “GPACU” beginning January 12, 2021. Each unit consists of (i) one Class A ordinary share, (ii) one-sixth of one redeemable warrant and (iii) the contingent right to receive, in certain circumstances, another one-sixth of one redeemable warrant at the time of the Company’s initial business combination. Each whole warrant entitles the holder thereof to purchase one Class A ordinary share of the Company at a price of $11.50 per share. Once the securities comprising the units begin separate trading, the Class A ordinary shares and warrants are expected to be listed on Nasdaq under the symbols “GPAC” and “GPACW”, respectively. The offering is expected to close on January 14, 2021, subject to customary closing conditions.

UBS Securities LLC and RBC Capital Markets, LLC are acting as joint book running managers for the offering. The Company has granted the underwriters a 45-day option to purchase up to an additional 2,500,000 units at the initial public offering price to cover over-allotments, if any.

The offering is being made only by means of a prospectus. Copies of the prospectus may be obtained from UBS Securities LLC, Attention: Prospectus Department, 1285 Avenue of the Americas, New York, NY 10019, or by telephone at (888) 827-7275 or email at
[email protected], or RBC Capital Markets, LLC, Attention: Equity Syndicate, 200 Vesey Street, 8th Floor, New York, NY 10281, or by telephone at (877) 822-4089 or email at [email protected].

A registration statement relating to the securities became effective on January 11, 2021. This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or other jurisdiction.

Cautionary Note Concerning Forward-Looking Statements

This communication contains statements that constitute “forward-looking statements,” including with respect to the closing of the Company’s proposed initial public offering and the anticipated use of the net proceeds from the offering. No assurance can be given that the offering will be completed on the terms described, or at all, or that the net proceeds will be used as indicated. Forward-looking statements are subject to numerous risks and uncertainties, many of which are beyond the control of the Company, including those set forth in the Risk Factors section of the Company’s registration statement and preliminary prospectus relating to the offering, as filed with the U.S. Securities and Exchange Commission (“SEC”). Copies are available on the SEC’s website, www.sec.gov. The Company undertakes no obligation to update these statements after the date of this release, except as required by law.

About Global Partner Acquisition Corp II

Global Partner Acquisition Corp II is a blank check company formed for the purpose of entering into a merger, share exchange, asset acquisition, share purchase, reorganization or similar business combination with one or more businesses. Although the Company may pursue a business combination target in any business, industry or sector, the Company intends to focus its efforts on completing a business combination with a company in one of the following sectors: consumer; food; branded products; e-commerce and retail disruptors; and the consumerization of healthcare, as well as certain service sectors and the technology driving changes across these sectors and related industries. The Company believes that its combined team’s capabilities were demonstrated in the sourcing and completion of the GPAC I merger with Purple Innovation Inc., as well as the team’s significant work with Purple since the closing of that merger.

Contacts

Global Partner Acquisition Corp II
Paul Zepf
(917) 244-4880