Canopy Growth announces completion of study on the long-term effects of CBD

PR Newswire

Study represents the first research completed on the long-term toxicity and lifespan effects of cannabidiol in the preclinical model C. elegans

SMITHS FALLS, ON, Nov. 23, 2020 /PRNewswire/ – Canopy Growth Corporation (“Canopy Growth” or the “Company”) (TSX: WEED) (NASDAQ: CGC) and its medical division, Spectrum Therapeutics, have completed and published a new study on the long-term effects of cannabidiol (CBD), specifically focusing on toxicity and lifespan effects of CBD in the preclinical model C. elegans.

The study was commissioned to evaluate the solubility, stability, acute toxicity, thermotolerance, and effects on lifespan of CBD in C. elegans as part of Canopy Growth’s ongoing commitment to provide the data required to support and influence public policy through research. To the best of the Company’s knowledge, this study represents the first long-term toxicity and lifespan research regarding the effects of chronic exposure to cannabidiol – one of the cannabinoids found in cannabis.

Acute and long-term exposure studies of CBD at physiologically relevant concentrations were studied in the worm model Caenorhabditis elegans (C. elegans) on the basis that 60-80% of their genes are shared with humans, and their comparatively short lifespan of 2-3 weeks makes such studies feasible. In the C. elegans model, which is recognized as a valid model for this kind of research, CBD did not demonstrate any degree of acute or life-long toxicity or related liabilities at physiological concentrations. Instead, CBD extended mean lifespan up to 18% and increased late-stage life activity by up to 206% compared to the untreated controls within the study.

“Despite widespread use of CBD, no life-long toxicity studies had been conducted to date to determine the impact – or potential impact – of long-term exposure to CBD,” shared Hunter Land, Senior Director of Translational and Discovery Science at Canopy Growth. “These results serve as the only CBD life-long exposure data in an in vivo model to date, and the absence of long-term toxicity gives us the evidence we need as an industry to continue researching the potential health benefits for the broader application of CBD.”

The study was conducted in partnership with NemaLife Inc., and is published in Cannabis and Cannabinoid Research journal and available online.

While further research into the life-long use of CBD should be carried out in mammalian models, the C. elegans model indicates a lack of long-term toxicity at physiologically relevant concentrations. Canopy Growth and its medical division Spectrum Therapeutics continue to advance a range of research initiatives aimed at furthering the understanding of – and unleashing – the full potential of cannabis.

About Canopy Growth Corporation

Canopy Growth (TSX:WEED,NASDAQ:CGC) is a world-leading diversified cannabis and cannabinoid-based consumer product company, driven by a passion to improve lives, end prohibition, and strengthen communities by unleashing the full potential of cannabis. Leveraging consumer insights and innovation, we offer product varieties in high quality dried flower, oil, softgel capsule, infused beverage, edible, and topical formats, as well as vaporizer devices by Canopy Growth and industry-leader Storz & Bickel. Our global medical brand, Spectrum Therapeutics, sells a range of full-spectrum products using its colour-coded classification system and is a market leader in both Canada and Germany. Through our award-winning Tweed and Tokyo Smoke banners, we reach our adult-use consumers and have built a loyal following by focusing on top quality products and meaningful customer relationships. Canopy Growth has entered into the health and wellness consumer space in key markets including Canada, the United States, and Europe through BioSteel sports nutrition, and This Works skin and sleep solutions; and has introduced additional federally-permissible CBD products to the United States through our First & Free and Martha Stewart CBD brands. Canopy Growth has an established partnership with Fortune 500 alcohol leader Constellation Brands. For more information visit www.canopygrowth.com.

Notice Regarding Forward Looking Statements

This press release contains “forward-looking statements” and “forward-looking information” within the meaning of applicable U.S. and Canadian securities laws (collectively, “forward-looking statements”), which involve certain known and unknown risks and uncertainties. Forward-looking statements predict or describe our future operations, business plans, business and investment strategies and the performance of our investments. These forward-looking statements are generally identified by their use of such terms and phrases as “intend,” “goal,” “strategy,” “estimate,” “expect,” “project,” “projections,” “forecasts,” “plans,” “seeks,” “anticipates,” “potential,” “proposed,” “will,” “should,” “could,” “would,” “may,” “likely,” “designed to,” “foreseeable future,” “believe,” “scheduled” and other similar expressions. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date the statement was made. Forward–looking statements are necessarily based upon a number of estimates and assumptions that, while considered reasonable by management, are inherently subject to significant business, economic and competitive risks, financial results, results, performance or achievements expressed or implied by those forward–looking statements and the forward–looking statements are not guarantees of future performance. Accordingly, there are or will be important factors that could cause actual outcomes or results to differ materially from those indicated in these statements. A discussion of some of the material factors applicable to Canopy Growth Corporation (“Canopy”) can be found under the section entitled “Risk Factors” in Canopy’s Annual Report on Form 10-K for the year ended March 31, 2020, filed with the Securities and Exchange Commission and with applicable Canadian securities regulators, as such factors may be further updated from time to time in its periodic filings with the Securities and Exchange Commission and with applicable Canadian securities regulators, which can be accessed at www.sec.gov/edgar and www.sedar.com, respectively. These factors should not be construed as exhaustive and should be read in conjunction with the other cautionary statements that are included in this press release and in the filings. Any forward–looking statement included in this press release is made as of the date of this press release and, except as required by law, Canopy disclaims any obligation to update or revise any forward– looking statement. Readers are cautioned not to put undue reliance on any forward–looking statement. Forward-looking statements contained in this press release are expressly qualified by this cautionary statement.

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SOURCE Canopy Growth Corporation

Milestone Pharmaceuticals to Present at Upcoming Investor Conferences

PR Newswire

MONTREAL and CHARLOTTE, N.C., Nov. 23, 2020 /PRNewswire/ — Milestone Pharmaceuticals Inc. (Nasdaq: MIST), a biopharmaceutical company focused on the development and commercialization of innovative cardiovascular medicines, today announced that Joseph Oliveto, President and Chief Executive Officer, will present at the following investor conferences:

  • The Piper Sandler 32nd Virtual Annual Healthcare Conference.
  • The Evercore ISI 3rd Annual HealthCONx Conference on Thursday, December 3, 2020 at 4:20 p.m. Eastern Time.

A replay of the pre-recorded Piper Sandler fireside chat is currently available in the News & Events section of Milestone’s website at www.milestonepharma.com, and a live webcast of the Evercore fireside chat can be accessed in the same section of Milestone’s website. An archived replay of the webcasts will be available on the same website for approximately 90 days following the presentations.

About Milestone Pharmaceuticals

Milestone Pharmaceuticals is a biopharmaceutical company focused on the development and commercialization of etripamil, a Phase 3 clinical-stage program, for the treatment of cardiovascular indications. Milestone Pharmaceuticals operates in Canada and the United States. For more information, visit www.milestonepharma.com and follow the Company on Twitter at @MilestonePharma. 

Contact

David Pitts

Argot Partners
212-600-1902
[email protected]

 

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SOURCE Milestone Pharmaceuticals, Inc.

Oxford Biomedica notes AstraZeneca’s AZD1222 met primary efficacy endpoint in preventing COVID-19

Oxford Biomedica notes AstraZeneca’s AZD1222 met primary efficacy endpoint in preventing COVID-19

         

Oxford, UK – 23 November, 2020: Oxford Biomedica plc (LSE:OXB) (“Oxford Biomedica” or “the Group”), a leading gene and cell therapy group, notes AstraZeneca PLC (“AstraZeneca”) announced AZD1222 met primary efficacy endpoint in preventing COVID-19.

Key highlights from the announcement were as follows:

  • Two different dosing regimens demonstrated efficacy with one showing a better profile
  • No hospitalisations or severe cases of COVID-19 in participants treated with AZD1222
  • One dosing regimen (n=2,741) showed vaccine efficacy of 90% when AZD1222 was given as a half dose followed by a full dose at least one month apart, and another dosing regimen (n=8,895) showed 62% efficacy when given two full doses at least one month apart
  • No serious safety events related to the vaccine have been confirmed
  • AstraZeneca will now immediately prepare regulatory submission of data to authorities around the world that have a framework in place for conditional or early approval

To view the full announcement from AstraZeneca, please follow this link: (LINK)

As announced on 1 September, Oxford Biomedica signed an 18 month supply agreement under a three year Master Supply and Development Agreement with AstraZeneca for large-scale commercial manufacture of their COVID-19 vaccine candidate, AZD1222. Under the terms of the agreement, AstraZeneca paid Oxford Biomedica £15 million upfront as a capacity reservation fee and the Group expects additionally to receive in excess of £35 million for large-scale manufacture of multiple batches of ADZ1222 until the end of 2021 subject to continuation of the programme. (LINK)

John Dawson, Chief Executive Officer of Oxford Biomedica, said:
“We are delighted to see the news today of the positive results from AstraZeneca for the COVID-19 vaccine, AZD1222. We are working hard to provide AstraZeneca with multiple large-scale batches of AZD1222 from our recently approved commercial manufacturing centre Oxbox. I am proud that Oxford Biomedica is part of the process that aims to bring normality back to many people around the world and I also personally want thank all our staff for their dedication and effort in production of the vaccine, whilst continuing to grow our core lentiviral vector business.”

-Ends-

 

 

 

 

 

Enquiries:

 
 

Oxford Biomedica plc

 

John Dawson, Chief Executive Officer
Stuart Paynter, Chief Financial Officer
Catherine Isted, Head of Corporate Development & IR

 

 

 

 

T: +44 (0)1865 783 000
T: +44 (0)1865 783 000
T: +44 (0)1865 954 161 / E: [email protected]

 

 

Consilium Strategic Communications

 

Mary-Jane Elliott/Matthew Neal

 

 

 

T: +44 (0)20 3709 5700

About Oxford Biomedica

Oxford Biomedica (LSE:OXB) is a leading, fully integrated, gene and cell therapy group focused on developing life changing treatments for serious diseases. Oxford Biomedica and its subsidiaries (the “Group”) have built a sector leading lentiviral vector delivery platform (LentiVector®), which the Group leverages to develop in vivo and ex vivo products both in-house and with partners. The Group has created a valuable proprietary portfolio of gene and cell therapy product candidates in the areas of oncology, ophthalmology, CNS disorders, liver diseases and respiratory disease. The Group has also entered into a number of partnerships, including with Novartis, Bristol Myers Squibb, Sanofi, Sio Gene Therapies, Orchard Therapeutics, Santen, Beam Therapeutics, Boehringer Ingelheim, the UK Cystic Fibrosis Gene Therapy Consortium and Imperial Innovations, through which it has long-term economic interests in other potential gene and cell therapy products. Additionally the group has signed a 3 year master supply and development agreement with AstraZeneca for large-scale manufacturing of the adenoviral based COVID-19 vaccine candidate, AZD1222. Oxford Biomedica is based across several locations in Oxfordshire, UK and employs more than 580 people. Further information is available at www.oxb.com



Oxford Biomedica Appoints Dr. Sam Rasty as Non-Executive Director

Oxford Biomedica Appoints Dr. Sam Rasty as Non-Executive Director

         

Oxford, UK – 23 November, 2020: Oxford Biomedica plc (LSE:OXB) (“Oxford Biomedica” or “the Group”), a leading gene and cell therapy group, is pleased to announce that, with effect from 1 December 2020, Dr. Siyamak (“Sam”) Rasty has been appointed to the Group’s Board as a Non-Executive Director.

Dr. Rasty brings more than 20 years of leadership experience in biopharma R&D, commercial, business development, strategy and operations at global large and medium-sized pharmaceutical and early stage, private biotechnology companies. He is currently the President and Chief Executive Officer of PlateletBio, a US-based pioneering cell-based therapeutics company. Previously, he served as Chief Operating Officer at Homology Medicines, Inc., a genetic medicines company that he helped launch in 2016, having played a key role in transforming the company from a private start-up to an established, fully integrated public gene therapy and gene editing company.  Prior to joining Homology, he held senior positions at Shire Pharmaceuticals, including as Vice President and Head of New Products, Director of Corporate Development at Endo Pharmaceuticals, and Director of Portfolio Management, Business & Commercial Analysis and Global Commercial Strategy at GlaxoSmithKline. Dr. Rasty holds a Ph.D. in Biochemistry from Louisiana State University, where he focused on transcriptional regulation of lentiviruses, completed a postdoctoral fellowship in Molecular Genetics and Biochemistry at the University of Pittsburgh School of Medicine, and received an MBA from Villanova University.

There are no disclosures required to be made in accordance with LR 9.6.13R.

Dr. Roch Doliveux
, Non-Executive Chairman of Oxford Biomedica, said:
“We are delighted that Sam is joining our Board of Directors. He brings significant experience to the Group from both his CEO role at PlateletBio and his previous COO role at Homology, both in the US.  Having already been involved in building and growing successful gene and cell therapy companies, Sam brings an invaluable combination of leadership, strategy and operational knowledge to the Board at this important time.”

Dr. Sam Rasty added:
“Gene and cell therapies are the new frontier in medicine, addressing previously untreatable human diseases and revolutionising treatment paradigms for patients.  As such, I am delighted to be joining the Board of Oxford Biomedica, a Group that has played a central role in key innovations in gene therapy and development of the industry.”

-Ends-

 

 

Enquiries:

 
 

Oxford Biomedica plc

 

John Dawson, Chief Executive Officer
Stuart Paynter, Chief Financial Officer
Catherine Isted, Head of Corporate Development & IR

 

 

 

 

T: +44 (0)1865 783 000
T: +44 (0)1865 783 000
T: +44 (0)1865 954 161 / E: [email protected]

 

 

Consilium Strategic Communications

 

Mary-Jane Elliott/Matthew Neal

 

 

 

T: +44 (0)20 3709 5700

About Oxford Biomedica

Oxford Biomedica (LSE:OXB) is a leading, fully integrated, gene and cell therapy group focused on developing life changing treatments for serious diseases. Oxford Biomedica and its subsidiaries (the “Group”) have built a sector leading lentiviral vector delivery platform (LentiVector®), which the Group leverages to develop in vivo and ex vivo products both in-house and with partners. The Group has created a valuable proprietary portfolio of gene and cell therapy product candidates in the areas of oncology, ophthalmology, CNS disorders, liver diseases and respiratory disease. The Group has also entered into a number of partnerships, including with Novartis, Bristol Myers Squibb, Sanofi, Sio Gene Therapies, Orchard Therapeutics, Santen, Beam Therapeutics, Boehringer Ingelheim, the UK Cystic Fibrosis Gene Therapy Consortium and Imperial Innovations, through which it has long-term economic interests in other potential gene and cell therapy products. Additionally the group has signed a 3 year master supply and development agreement with AstraZeneca for large-scale manufacturing of the adenoviral based COVID-19 vaccine candidate, AZD1222. Oxford Biomedica is based across several locations in Oxfordshire, UK and employs more than 580 people. Further information is available at www.oxb.com



Summit Therapeutics Appoints Dr. Mahkam (“Maky”) Zanganeh as Chief Operating Officer

Summit Therapeutics Inc.

(‘Summit,’ the ‘Company,’ or the ‘Group’)

Summit Therapeutics Appoints Dr. Mahkam (“Maky”) Zanganeh as Chief Operating Officer

Cambridge, MA, November 23, 2020 – Summit Therapeutics Inc. (NASDAQ: SMMT) announces that Dr. Mahkam “Maky” Zanganeh, DDS, MBA, has been appointed as Chief Operating Officer, effective immediately.  Dr. Zanganeh is currently a member of the Company’s Board of Directors, having been appointed on November 11, 2020. 

“Maky’s strategic leadership and operational expertise provide immeasurable value to Summit, as she joins us during this critical time within our ongoing Phase 3 clinical trials of our precision antibiotic candidate, ridinilazole, where we seek to bring a superior treatment to patients with C. difficile infection,” said Bob Duggan, Executive Chairman and Chief Executive Officer of Summit. “Maky’s proven track record of translating strategic objectives into results will help propel our Company as we build a viable, long-lasting health care organization that improves quality of life, increases potential duration of life, and resolves medical health care needs.”

Dr. Zanganeh joins Summit from Maky Zanganeh and Associates (“MZA”), which provides consulting services to businesses in product development, research, and transactions, where she is the President and CEO. Prior to founding and leading MZA, Dr. Zanganeh held multiple leadership positions at Pharmacyclics, Inc., from 2008 to 2015, culminating in her role as Chief Operating Officer, where she oversaw all clinical, research, commercial, and business-related matters. Dr. Zanganeh played a key role in the multimillion-dollar collaboration and license deal for ibrutinib with Janssen Biotech, Inc. in 2011, and the subsequent sale of Pharmacyclics to Abbvie Inc. in 2015.   She is currently a board member for Pulse BioSciences, Inc., and RenovoRx, Inc.  Dr. Zanganeh received her DDS from the Louis Pasteur University (France) and her MBA from Schiller International University (France). 

“The opportunity that Summit has to change the standard of care for infectious diseases, starting with ridinilazole, and improve the long-term quality of life of patients is pivotal to the antibiotics landscape,” stated Dr. Zanganeh.  “I look forward to expanding my role with a team of world class scientists and business leaders in assisting with the continuing build out of a powerful, sustainable business model to develop and commercialize our novel antibiotics, as we improve outcomes for patients and create healthcare savings in the process.”

About Summit Therapeutics

Summit Therapeutics, empowered by its Discuva Platform, the Company’s innovative antibiotic discovery engine, supported by BARDA and Carb-X funding, intends to be the leader in patient- and physician-friendly, paradigm-shifting antibiotic innovation. Our new mechanism antibiotics are designed to become the patient-friendly, new-era standard of care, by working in harmony with the human microbiome to treat prospective patients suffering from infectious disease, initially focusing on Clostridioides difficile infections (“CDI”) which is estimated to impact over 3 million patients worldwide annually. Commercialization of ridinilazole for the treatment and the reduction of recurrence of CDI is subject to regulatory approvals. The overriding objective of Summit Therapeutics is to create value for patients, hospital infectious disease caregivers, community-based infectious disease healthcare providers, as well as healthcare payors around the world.  Currently, Summit’s lead product candidate, ridinilazole, is engaged in two global Phase III trials, Ri-CoDIFy 1 & 2, each enrolling 680 patients vs. the standard of care (Vancomycin) for the treatment and reduction of recurrence of C. difficile infections.

Summit’s vision and mission is to extend our pipeline through the development of new mechanism, narrow spectrum, microbiome-sparing antibiotics targeting C. difficile, Gram-negative Enterobacteriaceae, such as Escherichia coli and Klebsiella pneumoniae, and other bacterial infections with high unmet medical need.

For more information, visit www.summittxinc.com and follow us on Twitter @summitplc. For more information on the Company’s Discuva Platform, visit https://www.summittxinc.com/our-science/discuva-platform.

Contract Summit Investor Relations:

Dave Gancarz

Vice President, Investor Relations & Corporate Strategy

[email protected]

General Inquiries: 

[email protected]

Summit Forward-looking Statements

Any statements in this press release about the Company’s future expectations, plans and prospects, including but not limited to, statements about the clinical and preclinical development of the Company’s product candidates, the therapeutic potential of the Company’s product candidates, the potential commercialization of the Company’s product candidates, the timing of initiation, completion and availability of data from clinical trials, the potential submission of applications for marketing approvals, the impact of the COVID-19 pandemic on the Company’s operations and clinical trials and other statements containing the words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “would,” and similar expressions, constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including: the uncertainties inherent in the initiation of future clinical trials, availability and timing of data from ongoing and future clinical trials and the results of such trials, global public health crises, including the coronavirus COVID-19 outbreak, that may affect timing and status of our clinical trials and operations, whether preliminary results from a clinical trial will be predictive of the final results of that trial or whether results of early clinical trials or preclinical studies will be indicative of the results of later clinical trials, expectations for regulatory approvals, laws and regulations affecting government contracts and funding awards, availability of funding sufficient for the Company’s foreseeable and unforeseeable operating expenses and capital expenditure requirements and other factors discussed in the “Risk Factors” section of filings that the Company makes with the Securities and Exchange Commission. Accordingly, readers should not place undue reliance on forward-looking statements or information. In addition, any forward-looking statements included in this press release represent the Company’s views only as of the date of this release and should not be relied upon as representing the Company’s views as of any subsequent date. The Company specifically disclaims any obligation to update any forward-looking statements included in this press release.



PLAYING FOR CHANGE AND THE UNITED NATIONS POPULATION FUND ANNOUNCE “PEACE THROUGH MUSIC: A GLOBAL EVENT FOR SOCIAL JUSTICE”

A FACEBOOK EXCLUSIVE IN CELEBRATION OF THE 75TH ANNIVERSARY OF THE UNITED NATIONS

Los Angeles, New York, Nov. 23, 2020 (GLOBE NEWSWIRE) — PLAYING FOR CHANGE AND THE UNITED NATIONS POPULATION FUND ANNOUNCE

“PEACE THROUGH MUSIC: A GLOBAL EVENT FOR SOCIAL JUSTICE”

– A FACEBOOK EXCLUSIVE IN CELEBRATION OF THE 75TH ANNIVERSARY OF THE UNITED NATIONS

 

FEATURING PERFORMANCES BY: ALOE BLACC, ANGÉLIQUE KIDJO, ANNIE LENNOX, BECKY G, BRANDI CARLILE WITH MIKE MCCREADY OF PEARL JAM, CARLOS SANTANA AND CINDY BLACKMAN SANTANA, GABI MELIM, GARY CLARK JR., JACK JOHNSON, JIM JAMES, KEB’ MO’, MAVIS STAPLES, NATHANIEL RATELIFF, PETER GABRIEL, RHIANNON GIDDENS, RINGO STARR, ROBBIE ROBERTSON, ROBERT RANDOLPH, RUN THE JEWELS WITH JOSH HOMME, SHEILA E., SHEMEKIA COPELAND, SKIP MARLEY AND CEDELLA MARLEY, THE WAR AND TREATY, YO-YO MA …. AND MANY MORE

 

SPECIAL APPEARANCES BY:  BILLIE EILISH, ELLIE GOULDING, KILLER MIKE, MEGAN RAPINOE AND SUE BIRD, NORMAN LEAR, PRINCE EA, SARA BAREILLES AND MORE

 

PRODUCED BY PLAYING FOR CHANGE AND BLACKBIRD PRESENTS

 


WATCH TRAILER HERE

 

ALL-STAR EVENT TO PREMIERE EXCLUSIVELY ON


FACEBOOK

LIVE THIS GIVINGTUESDAY, DECEMBER 1, 2020 at 12 pm PST / 3 pm EST

 

VISIT

PEACETHROUGHMUSIC.LIVE/

FOR MORE INFORMATION

AND WATCH IT LIVE IN THE

PLAYING FOR CHANGE FACEBOOK PAGE

 

In honor of the 75th Anniversary of the United Nations and GivingTuesday, Playing For Change and UNFPA, the United Nations Population Fund, are thrilled to announce Peace Through Music: A Global Event for Social Justice, produced by Playing For Change and Blackbird Presents, exclusively on Facebook Live on December 1, 2020.

 

The global virtual event will inspire people to act for peace, justice and equity, everywhere and for everyone. It will feature performances from some of the world’s most iconic artists, including: Aloe Blacc, Angélique Kidjo, Annie Lennox, Becky G, Brandi Carlile with Mike McCready of Pearl Jam, Carlos Santana and Cindy Blackman Santana, Gabi Melim, Gary Clark Jr., Jack Johnson, Jim James, Keb’ Mo’, Mavis Staples, Nathaniel Rateliff, Peter Gabriel, Rhiannon Giddens, Ringo Starr, Robbie Robertson, Robert Randolph, Run The Jewels with Josh Homme, Sheila E., Skip Marley and Cedella Marley, The War and Treaty, Yo-Yo Ma and many more. Special appearances include Billie Eilish, Ellie Goulding, Killer Mike, Megan Rapinoe and Sue Bird, Norman Lear, Prince Ea and Sara Bareilles.

 

Through the universal language of music and the art of storytelling, the event will call for equality, human rights, and an end to discrimination, spotlighting people of African descent and championing the full protection and promotion of human rights for all. It will embody the unity and common purpose that beat in the heart of humanity.


 


Peace Through Music: A Global Event for Social Justice
will premiere exclusively on Facebook Live on the Playing For Change Facebook Page on GivingTuesday (December 1, 2020 at 12 pm PST / 3 pm EST). GivingTuesday is a global generosity movement unleashing the power of people and organizations to transform their communities and the world.

 

Contributions from partners and all donations made to Peace Through Music’s Facebook Fundraiser will support the Playing For Change Foundation, the United Nations Population Fund, Sankofa, Silkroad, and The Rock & Roll Hall of Fame Foundation – organizations that strive to eradicate poverty, inequality, and systemic racial and gender discrimination around the world.

 

“We are stronger together than we are apart, and it is an honor to partner with like-minded artists and charities that echo this sentiment. The power of music is one tool we can use to unite and eradicate racism, inequality, poverty, and all other diseases that have plagued our world for much too long. The things in life that divide us, disappear when the music plays, and that’s something we hope you see and feel during this event,” says Mark Johnson, Playing For Change Co-Founder.

 

“Music is a wonderful medium to raise awareness about our collective quest for peace, justice, equality and dignity – the noble ideals of the United Nations. It is a powerful, unifying language that can help build bridges and advance social justice in all of its forms,” says Dr. Natalia Kanem, Executive Director of the United Nations Population Fund.

 

“We need to rediscover and reassert the language of our unity, of our common fears and common hopes, forged through the crucible of the pandemic.  And what better example is there of a common language beyond our differences, notwithstanding our divisions, than music? We are delighted to be a part of this exciting event, advocating for social justice, and in honor of UN75,” says Fabrizio Hochschild, Special Adviser on the Preparations for the Commemoration of the United Nations’ 75th Anniversary.

 

“We are honored to work with artists and organizations that share in the values of peace, justice, and equality for all humans. This event is a reflection of these values at a time when they are sorely needed in this world,” says Keith Wortman, Founder, and CEO of Blackbird Presents.

 

“On Giving Tuesday, people all over the world come together to support great causes and give something back,” says Sheryl Sandberg, Chief Operating Officer of Facebook. “We are proud to be working with Playing For Change to inspire people everywhere to work toward a more peaceful, just and equal world for everyone.”

 

Full Lineup:

Afro Fiesta, Abiodun Oyewale (The Last Poets), Ahmed Al Harmi, Al Harban Brothers, Alcione, Alfred Howard, Ali Boulala, Aloe Blacc, Amina J. Mohammed (UN), Angélique Kidjo, Annie Lennox, Azueï, Baaba Maal, Barou Sall, Becky G, Béla Fleck, Bill Kreutzmann (Grateful Dead),Bill Summers,Billie Eilish, Binho, Bizung Family Band, Brandi Carlile with Mike McCready of Pearl Jam, Carl C-Wyya Edwards, Carlos Santana and Cindy Blackman Santana, Chandrajit and Venkat, Chango Spasiuk, Char, Clarence Bekker, Cristina Pato, Congo Drums, Cory Henry, Courtney “Bam” Diedrick, Donald Harrison and Congo Square Nation, Dr. John, Dr. Michael Eric Dyson, Dudu Nobre, Dynamic Music Collective, EduMundo and Caveman, Ellie Goulding, Eyadou Ag Leche, Fabián Miodownik, Gabi Melim, Gary Clark Jr., George Porter Jr., Grandpa Elliott, Guardians Of The New Fire, Hiromitsu Agatsuma, Hutch Hutchinson, Ibram X. Kendi, Ibrahim Ag Alhabib, Ivan Neville, Isabella Madrigal, Jack Johnson, Jaiksona Soto, Jamal Murray,Jane Elliott, Jim James, John Cruz, John Prine, Johnny Herno, Kasha Sequoia Slavner, Keb’ Mo’, Keiko Komaki, Killer Mike, Kimberly L. Jones, Kolgate, La Escuelita del Ritmo, Larkin Poe, Los Hijos de Benkos, Louis Mhlanga, Lukas Nelson, Mamadou Sarr, Marcus King, Mark Johnson, Mark Lozano, Massamba Diop, Mateo, Mavis Staples, Megan Rapinoe and Sue Bird, Mermans Mosengo, Meshell Ndegeocello, Mickey Hart (Grateful Dead), Mohammed Alidu, Nasreen Sheikh, Natalia Kanem (UNFPA), Nathaniel Rateliff, Nikki Burt, Norm, Norman Lear, Ousseynou and Assane Kaba, “Papi” Felix Garemua, Patrick Simmons (The Doobie Brothers), Paulo Heman, Peter Bunetta, Peter Gabriel, Playing For Change Band, Playing For Change Foundation, Prince Ea, Pyramid Lake, Paiute Tribe, Rahat Inayat Ali, Rajeev Shrestha, Reggie McBride,Rhiannon Giddens, Ringo Starr, Robbie Robertson, Robert Randolph, Roberto Luti, Robin Moxey, Roger Ridley, Rubén Rada and Family, Rudson Daniel and Enio Taquari, Run The Jewels with Josh Homme, Sanjay Shrestha, Sean “Pow” Diedrick, Sebastian Robertson, Sexteto Tabala, Sara Bareilles,Sheila E., Shemekia Copeland, Sherieta Lewis & Roselyn Williams, Skip Marley and Cedella Marley, Sol Homar, Songhoy Blues, Taikoproject, Taimane, Tal Wilkenfeld, Taslima Khan, The Cape Town Ensemble, The Silkroad Ensemble, The War and Treaty, Tito Puente Jr., Toumani Diabaté, TP OK Jazz, Tula Ben Ari, Tushar Lall, Vusi Mahlasela, Washboard Chaz, Whitney Kroenke Silverstein, Yo-Yo Ma, Zulu Choir.

 

For more information about Peace Through Music: A Global Event for Social Justice, please visit peacethroughmusic.live. Watch it live on December 1 through the Playing For Change Facebook Page.


About Playing For Change 

Playing For Change (PFC) is a movement created to inspire and connect the world through music, born from the shared belief that music has the power to break down boundaries and overcome distances between people. PFC spreads their positive message for humanity to millions of people through inspiring multicultural music videos, a live global touring band and a 501c3 foundation supporting music education around the world.

 

About Playing For Change Foundation

Founded in 2007, the Playing For Change Foundation was established to create positive change through music and arts education. Its work engages marginalized youth in low income, yet culturally rich, communities around the world. Utilizing local music, teachers, and infrastructure, each student is able to rise up through music, dance, arts, sports, and much more, all within their own culture. It currently operates 15 music programs in 11 countries, teaches over 3,000 kids each week, and has positively impacted more than 40,000 lives of kids and families in need. The Foundation was awarded the Polar Music Prize in 2019.

 

About the United Nations Population Fund

UNFPA is the United Nations sexual and reproductive health agency. It is formally named the United Nations Population Fund. UNFPA’s mission is to deliver a world where every pregnancy is wanted, every childbirth is safe and every young person’s potential is fulfilled. UNFPA calls for the realization of reproductive rights for all and supports access to a wide range of sexual and reproductive health services, including voluntary family planning, quality maternal health care and comprehensive sexuality education.

 

About UN75

To mark its 75th anniversary in 2020, the United Nations launched the world’s largest global conversation on ‘the future we want’. UN75 invites people everywhere to imagine the future they want and contribute ideas on how to make it a reality, building a better and more sustainable world, for all. It is also the largest survey to date on priorities for recovering from the COVID-19 pandemic. To date, over a million people from all countries and all walks of life have had their say. Their answers provide unique insights into what the public wants at this challenging time for the world. 

 

About Blackbird Presents

Blackbird Presents is a leading global media company that creates and produces premium, music-driven events and content via a range of strategies including all-star concert events, tours, festivals, broadcast specials, episodic series, and documentaries.

Recent concerts, broadcast specials and releases include “Willie: Life & Songs Of An American Outlaw,” “All In For The Gambler: Kenny Rogers’ Farewell Concert Celebration,” “Sing Me Back Home: The Music of Merle Haggard,” “The Life & Songs of Kris Kristofferson,” “Imagine: John Lennon 75th Birthday Concert,” “Outlaw: Celebrating The Music of Waylon Jennings,” “I’ll Take You There: Celebrating 75 Years of Mavis Staples,” “The Life and Songs of Emmylou Harris,” “Lynyrd Skynyrd: One More For The Fans,” “The Musical Mojo of Dr. John: Celebrating Mac and His Music” and “All My Friends: Celebrating The Songs and Voice of Gregg Allman,” the last of which earned a GRAMMY® Award nomination for Gregg Allman and Taj Mahal’s awe-inspiring performance of “Statesboro Blues. ”Blackbird Presents is also the creator and producer of The Outlaw Music Festival Tour, in partnership with Willie Nelson; The American Roots Music & Arts Festival, in partnership with Eric Church; and The Last Waltz 40 Tour in partnership with Robbie Robertson.

Attachment



Eddie Wright
UNFPA
917 831 2074
[email protected]

Alvaro Serrano
UNFPA
[email protected]

Ebie McFarland
Essential Broadcast Media
[email protected]

Band Protocol Partners with Digital Asset Data Company Brave New Coin to Bring Decentralized Price Reference Data to DeFi

Band and BNC bring globally weighted average spot prices for 1500+ digital assets to decentralized oracles

BANGKOK/AUCKLAND, Nov. 23, 2020 (GLOBE NEWSWIRE) — (via Blockchain Wire) Brave New Coin (https://bravenewcoin.com/), a leading data analytics and research company backed by Techemy Ltd, has joined forces with Sequoia-backed cross-chain data oracle platform Band Protocol to bring decentralized price reference data to the rapidly growing smart contract application ecosystem.

Band Protocol and Brave New Coin will work together to bring the globally weighted average spot prices for up to 1500+ digital assets through the BandChain decentralized oracle network. This will allow smart contract developers to readily integrate and utilize these spot price oracles on any blockchain platform. Band Protocol has already been integrated by leading smart contract platforms including Ethereum, Binance Smart Chain, Cosmos, Polkadot, ICON, Waves, and Matic Network.

“Brave New Coin is an early adopter and supporter of DeFi protocols, having launched the first crypto pricing data oracles for smart contracts in 2016,” said Fran Strajnar, CEO of Brave New Coin. “More recently, Brave New Coin has launched a tradable DeFi Index, of which the BAND token is a constituent. Together with Techemy Group, Brave New Coin and Band Protocol are leading the way in bringing scalable, decentralized and non-custodial products and solutions for trading, investment and analysis for smart contract developers to seamlessly utilize.”

“Working with established and reputable enterprises such as Brave New Coin will be pivotal to Band Protocol’s success as we collaborate to provide a commercial solution that protects intellectual property and data privacy while enabling the smart contract world to interact with external data sources,” said Soravis Srinawakoon, CEO and Co-Founder of Band Protocol.

This long-term partnership will also enable premium data source owners with paywalls such as Brave New Coin to automatically collect revenue on-chain starting next year. Band Protocol’s flexible oracle design benefits all stakeholders by allowing developers to create custom-made oracles with web APIs within minutes as well as enabling enterprises to commercialize their data by creating premium oracles for developers to integrate.

The Global Weighted Average Spot Price (GWA) provided by Brave New Coin works by providing a fair price for any tracked digital asset from near real-time trading across a global network of top crypto exchanges. With intraday, end of day price and volume inputs updated at a 30 second tick interval, developers in decentralized finance will be well equipped to build trustless applications using an independent, reliable, third-party price discovery oracle.

About Band Protocol

Band Protocol is a cross-chain data oracle platform that aggregates and connects real-world data and APIs to smart contracts. Blockchains are great at immutable storage and deterministic, verifiable computations — however, they cannot securely access data available outside the blockchain networks. Band Protocol enables smart contract applications such as DeFi, prediction markets, and games to be built on-chain without relying on the single point of failure of a centralized oracle. Band Protocol is backed by a strong network of stakeholders including Sequoia Capital, one of the top venture capital firms in the world, and the leading cryptocurrency exchange, Binance.

About Brave New Coin

Brave New Coin (https://bravenewcoin.com/) (BNC) is a data and research company focused on the blockchain and cryptographic assets industry. Founded in 2014, BNC provides data, analysis and research to a global network of market participants. Brave New Coin supplies spot-pricing, index solutions, research and news both aggregate and proprietary, via partners such as Amazon Alexa, Dow Jones Factiva, NASDAQ, Refinitv, RapidAPI and dozens more. The company’s experience and expertise make it the leading provider of standard and non-standard institutional grade, highly compliant, data solutions. BNC Pro leverages its experience and data into a user-friendly dashboard solution. 



MEDIA CONTACT: Transform Group, [email protected] 

Whitestone REIT Welcomes Firm Body Pilates Training Studio to its Citadel Community in Arizona 

Continues Adding Tenants that Meet the Needs of Local Neighborhoods

HOUSTON, Nov. 23, 2020 (GLOBE NEWSWIRE) — Whitestone REIT (NYSE: WSR) is pleased to announce the addition of Firm Body Pilates Training as a new tenant to its Citadel property in North Scottsdale, Arizona.

“Every moment of our life can be the beginning of great things.” — Joseph Pilates. 

“As the country embraces the re-opening of gyms and fitness centers in select areas across the nation, we are pleased to partner with such an experienced and well-respected fitness instructor and entrepreneur,” said Jim Mastandrea, Chairman and CEO of Whitestone REIT. “Pilates has been one of the few segments of the fitness industry that has shown resiliency despite the government-mandated shutdowns during the pandemic and has thrived due to its smaller class sizes and location flexibility. At Whitestone, we have always encouraged and supported the entrepreneurial spirit and are honored to collaborate with Jodi, her business and one of our high-quality properties to continue her pursuit of the American Dream. We envision Firm Body Pilates expanding its business into several of our other centers throughout the Greater Phoenix area and possibly in our high-growth Texas markets of Houston, Dallas-Ft. Worth, Austin, and San Antonio.”

Jodi Melton, owner of JM Pilates LLC, which will operate Firm Body Pilates Training, is an experienced instructor with over 40 years in the fitness industry and 14 years of successfully training and managing several high-end clients remotely in the DC Ranch area. Jodi is classically trained, certified through the PhysicalMind Institute, and qualified to train and certify new instructors. The new studio at Citadel, which is in close proximity to other Whitestone properties like Market Street at DC Ranch, represents her first pilates studio. Firm Body Pilates Training’s top priority in opening the new space is protecting the health and safety of its community and clients. The studio, which is in compliance with state and local COVID-19 protocols, is complete with top-of-the-line V2 MaxTM Reformer Bundle equipment from MerrithewTM

With an emphasis on health and wellness targeting physical core strengthening and rehabilitation, Firm Body Pilates has successfully provided services to a rapidly growing list of clients. Its diverse clientele range in age from 11 to 85 years old and in experience from pilates beginners to professional dancers and athletes, including members of the NFL’s Green Bay Packers and NHL’s Arizona Coyotes.

Mr. Mastandrea concluded, “The opening of Firm Body Pilates is another example of entrepreneurs stepping up to meet the pent-up demand for services in Whitestone spaces, benefitting the communities we serve.” 


About Whitestone REIT
 
Whitestone is a community-centered shopping center REIT that acquires, owns, manages, develops and redevelops high-quality neighborhood centers primarily in the largest, fastest-growing and most affluent markets in the Sunbelt. 

Whitestone seeks to create Communities That Thrive through Creating Local Connections between consumers in the surrounding communities and a well-crafted mix of national, regional and local tenants that provide daily necessities, needed services, entertainment and experiences.

Whitestone is a monthly dividend paying stock and has consistently paid dividends for over 15 years.

Whitestone’s strong balanced and managed capital structure provides stability and flexibility for growth and positions Whitestone to perform well through economic cycles. For additional information, please visit www.whitestonereit.com.


About


PhysicalMind


Institute®


PhysicalMind Institute® was established in 1991 to carry on the work of Joseph Pilates. Beginning with Certification of Pilates Teachers, the Institute continued the tradition of looking at bodies and inventing what was needed for better movement and pain relief. Today Pilates, Yoga, Barre and Dance professionals and consumers worldwide benefit from these patented, portable, and lightweight products such as Tye4®, Parasetter®, Head Floater® and more. These are the future of fitness. For additional information, please visit www.physicalmindinstitute.com.


About


Merrithew



TM



Founded in 1988 with the aim of developing high-integrity fitness education programs, equipment and services. Merrithew looks to help fitness professionals and enthusiasts fulfill their potential. Their philosophy is that effective and responsible exercise is the foundation of a better life – and should be accessible regardless of age, fitness level or ability. For additional information, please visit www.physicalmindinstitute.com.

Investors Contact:

Kevin Reed, Director of Investor Relations
Whitestone REIT
(713) 435-2219
[email protected]



Legend Biotech Announces New Appointment to the Board of Directors and Resignation of Dr. Fangliang Zhang

Legend Biotech Announces New Appointment to the Board of Directors and Resignation of Dr. Fangliang Zhang

SOMERSET, N.J.–(BUSINESS WIRE)–
Legend Biotech Corporation (NASDAQ: LEGN) (“Legend Biotech”), a global clinical-stage biopharmaceutical company engaged in the discovery and development of novel cell therapies for oncology and other indications, announced today that it has appointed Dr. Li Zhu to Legend Biotech’s Board of Directors. Dr. Zhu will serve as a Class III director.

In addition, Dr. Fangliang Zhang tendered his resignation from the Board of Directors of Legend Biotech and its committees, effective as of November 22, 2020. As announced on September 21, 2020, Dr. Zhang had been under residential surveillance in connection with an investigation by the Customs Anti-Smuggling Department of Zhenjiang (the “Authority”) in the People’s Republic of China, and he has now been formally placed under arrest. While no charges have been filed against him, Dr. Zhang decided that to avoid unnecessary distraction to Legend Biotech, his resignation would be in the interests of Legend Biotech and its shareholders. To date, no charges have been filed against Legend Biotech or any of its officers or directors, and Legend Biotech does not believe that it is a subject of the Authority’s investigation.

“The Board of Legend Biotech would like to take this opportunity to express its sincere gratitude and appreciation to Dr. Zhang for his valuable contribution to the company during his tenure of service,” said Sally Wang, Chairwoman of Legend Biotech. “We are excited to welcome Dr. Zhu to our Board of Directors. The addition of Dr. Zhu complements our Board’s skills and experiences, and we are confident he will provide valuable support to Legend Biotech’s strategic development and objective to bring innovative and impactful cell therapies toward potential registration and commercialization.”

Dr. Zhu served as the vice president of strategy of GenScript Biotech Corporation (“GenScript”) from March 2010 to February 2017, served as the chief strategy officer of GenScript from February 2017 to July 2019, and has served as a consultant for GenScript since July 2019. Upon his appointment as executive director of GenScript on November 22, 2020, he resumed his role as the chief strategy officer of GenScript. Before joining GenScript, Dr. Zhu worked at California-based Clontech Laboratories, Inc. as a director of molecular biology from January 1990 to March 2000. Dr. Zhu founded Genetastix Corporation, Inc., a biotech company focused on yeast-based antibody discovery, and served as president and chief executive officer from May 2000 to December 2005. Dr. Zhu then worked at biotech companies in China, serving as vice president of research at Cathay Biotech, Inc. from July 2006 to December 2008, and as vice president of HUYA Biomedical Technology (Shanghai) Co., Limited from January 2009 to December 2009. Dr. Zhu obtained a Bachelor of Science of Biology degree from the East China Normal University in June 1982 and a Doctor of Philosophy in molecular biology and immunology from Stanford University in July 1989.

About Legend Biotech

Legend Biotech is a global clinical-stage biopharmaceutical company engaged in the discovery and development of novel cell therapies for oncology and other indications. Our team of over 800 employees across the United States, China and Europe, along with our differentiated technology, global development, and manufacturing strategies and expertise, provide us with the strong potential to discover, develop, and manufacture cutting edge cell therapies for patients in need.

We are engaged in a strategic collaboration with Janssen Biotech, Inc. to develop and commercialize our lead product candidate, ciltacabtagene autoleucel, an investigational BCMA-targeted CAR-T cell therapy for patients living with multiple myeloma. This candidate is currently being studied in registrational clinical trials.

Cautionary Note Regarding Forward-Looking Statements

Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute “forward-looking statements” within the meaning of The Private Securities Litigation Reform Act of 1995. These statements include, but are not limited to, statements relating to statements relating to the investigation of the Customs Anti-Smuggling Department of the People’s Republic of China, Legend Biotech’s strategic development and objectives, and the potential contributions of its new board member. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” “would” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including the factors discussed in the “Risk Factors” section of the prospectus filed with the Securities and Exchange Commission on June 8, 2020. Any forward-looking statements contained in this press release speak only as of the date hereof, and Legend Biotech specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise. Readers should not rely upon the information on this page as current or accurate after its publication date.

For Investor Relations inquiries:

Jessie Yeung, Head of Corporate Finance and Investor Relations, Legend Biotech USA Inc. [email protected] or [email protected]

Surabhi Verma, Manager of Investor Relations and Corporate Communications, Legend Biotech USA Inc.

[email protected] or [email protected]

KEYWORDS: New Jersey United States North America

INDUSTRY KEYWORDS: Research Clinical Trials Biotechnology Health Pharmaceutical General Health Other Science Science Oncology

MEDIA:

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Greenwich LifeSciences Announces Second Publication and Second Poster Presentation of Phase III Clinical Trial of Potential Breakthrough Technology for Recurring Breast Cancer

Greenwich LifeSciences Announces Second Publication and Second Poster Presentation of Phase III Clinical Trial of Potential Breakthrough Technology for Recurring Breast Cancer

‒ Phase III clinical trial to be led by Baylor College of Medicine

‒ In the Phase IIb clinical trial, led by MD Anderson, no recurrences were observed in the HER2/neu 3+ adjuvant setting after median 5 years of follow-up, if the patient received the 6 primary intradermal injections over the first 6 months (p = 0.0338), with robust immune response, well-tolerated safety profile, and no reported serious adverse events

STAFFORD, Texas–(BUSINESS WIRE)–
Greenwich LifeSciences, Inc. (Nasdaq: GLSI) (the “Company”), a clinical-stage biopharmaceutical company focused on the development of GP2, an immunotherapy to prevent breast cancer recurrences in patients who have previously undergone surgery, today announced the publication of a second abstract at the San Antonio Breast Cancer Symposium (SABCS), jointly authored by Professor Mothaffar F. Rimawi, the Global Principal Investigator of the GP2 Phase III clinical trial, and the Executive Medical Director and Co-Leader of the Breast Cancer Program at the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine, and Professor C. Kent Osborne, Tina and Dudley Sharp Chair in Oncology and the founding Director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine. The abstract will be displayed as the Company’s second poster on Wednesday, December 9, 2020 in a virtual format with an introductory audio track.

The abstract highlights the design of the planned Phase III clinical trial. The trial is designed as a single registration trial that will include an interim analysis seeking conditional marketing approval from the FDA upon the interim analysis data read out followed by submission of a Biologics Licensing Application. The Phase III clinical trial aims to reproduce the Phase IIb study which concluded that completion of the first 6 intradermal injections of GP2 + GM-CSF safely elicited a potent immune response and reduced recurrence rates to 0% in HER2/neu 3+ patients, who received a standard course of trastuzumab after surgery.

Snehal Patel, CEO of Greenwich LifeSciences, commented, “The participation of Baylor College of Medicine as the Phase III clinical trial lead site further validates the significance of our Phase IIb data. Reducing the recurrence of breast cancer rates to 0% gives us great confidence as we try to reproduce this data in the Phase III clinical trial. We are addressing a potential market of up to $5 billion in a disease that affects 1 in 8 women, who if recur, will likely face metastatic breast cancer.”

“We are very excited to be working with such prominent key opinion leaders. Professor Rimawi’s leadership of our Phase III clinical trial will complement the positive Phase IIb clinical trial results with the research and clinical expertise of Baylor College of Medicine. Due to GP2’s efficacy and safety profile, GP2 immunotherapy may provide clinicians with an option to reduce the use of other toxic and expensive treatments. We look forward to sharing our Phase IIb clinical trial data and Phase III clinical trial design with breast cancer leaders attending SABCS and to discussing the participation of their clinical sites in our trial,” Patel concluded.

The Phase III clinical trial will explore the use of GP2 + GM-CSF as adjuvant therapy to prevent the recurrence of breast cancer in HER2/neu positive and HLA 2+ patients, post-surgery and following the first year of treatment with any trastuzumab-based therapy.

The Phase III clinical trial is a prospective, randomized, double-blinded, multi-center study. After 1 year of trastuzumab-based therapy or an approved biosimilar, treatment with GP2 + GM-CSF or placebo will be administered intradermally for the 6 primary immunization series over the first 6 months and 5 subsequent boosters over the next 2.5 years for a total of 11 injections over 3 years of treatment. The participant duration of the trial will be 3 years of treatment plus 2 years of follow-up for a total of 5 years following the first year of treatment with trastuzumab-based therapy or approved biosimilar. An interim analysis is planned and patients will be stratified based on prior and current treatments, among other factors.

The majority of breast cancer patients will be HER2/neu positive and HLA 2+, disease-free, conventionally treated node-positive, post breast tumor removal surgery and following the first year of treatment with trastuzumab-based therapy.

Abstract OT-13-03 is entitled: A prospective, randomized, multicenter, double-blinded, placebo-controlled Phase III trial of the HER2/neu peptide GP2 + GM-CSF versus bacteriostatic saline/WFI placebo as adjuvant therapy after any trastuzumab-based therapy in HER2-positive women with operable breast cancer. The full abstract can be viewed here on page 912.

About SABCS

The 43rd annual SABCS has grown to be the industry’s premier breast cancer conference for basic, translational, and clinical cancer research professionals. It is well-known for presenting the latest breast cancer data from all over the world. More than 7,500 health care professionals from more than 90 countries attend annually. Baylor College of Medicine became a joint sponsor of SABCS in 2005. The Cancer Therapy & Research Center at UT Health Science Center San Antonio and American Association for Cancer Research began collaborations with SABCS in 2007. For more information, please visit the conference website at: https://www.sabcs.org/

About Breast Cancer and HER2/neu Positivity

One in eight U.S. women will develop invasive breast cancer over her lifetime, with approximately 266,000 new breast cancer patients and 3.1 million breast cancer survivors in 2018. HER2/neu (human epidermal growth factor receptor 2) protein is a cell surface receptor protein that is expressed in a variety of common cancers, including in 75% of breast cancers at low (1+), intermediate (2+), and high (3+ or over-expressor) levels.

About Greenwich LifeSciences, Inc.

Greenwich LifeSciences is a clinical-stage biopharmaceutical company focused on the development of GP2, an immunotherapy to prevent breast cancer recurrences in patients who have previously undergone surgery. GP2 is a 9 amino acid transmembrane peptide of the HER2/neu protein. In a randomized, single-blinded, placebo-controlled, multi-center (16 sites led by MD Anderson Cancer Center) Phase IIb clinical trial, no recurrences were observed in the HER2/neu 3+ adjuvant setting after median 5 years of follow-up, if the patient received the 6 primary intradermal injections over the first 6 months (p = 0.0338). Of the 138 patients that have been treated with GP2 to date over 4 clinical trials, GP2 treatment was well tolerated and no serious adverse events were observed related to GP2 immunotherapy. Greenwich LifeSciences is planning to commence a Phase III clinical trial using a similar treatment regime as the Phase IIb clinical trial. For more information on Greenwich LifeSciences, please visit the company’s website: www.greenwichlifesciences.com

Forward-Looking Statement Disclaimer

Statements in this press release contain “forward-looking statements” that are subject to substantial risks and uncertainties. All statements, other than statements of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press release may be identified by the use of words such as “anticipate,” “believe,” “contemplate,” “could,” “estimate,” “expect,” “intend,” “seek,” “may,” “might,” “plan,” “potential,” “predict,” “project,” “target,” “aim,” “should,” “will” “would,” or the negative of these words or other similar expressions, although not all forward-looking statements contain these words. Forward-looking statements are based on Greenwich LifeSciences Inc.’s current expectations and are subject to inherent uncertainties, risks and assumptions that are difficult to predict. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate. These and other risks and uncertainties are described more fully in the section titled “Risk Factors” in the final prospectus related to the public offering filed with the Securities and Exchange Commission. Forward-looking statements contained in this announcement are made as of this date, and Greenwich LifeSciences Inc. undertakes no duty to update such information except as required under applicable law.

Company Contact

Snehal Patel

Investor Relations

(832) 819-3232

[email protected]

Investor & Public Relations Contact for Greenwich LifeSciences

Dave Gentry

RedChip Companies Inc.

Office: 1-800-RED CHIP (733 2447)

Cell: (407) 491-4498

[email protected]

KEYWORDS: Texas United States North America

INDUSTRY KEYWORDS: University Biotechnology Education Health Women Pharmaceutical Oncology Research Consumer Science Clinical Trials

MEDIA:

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