ROSEN, GLOBAL INVESTOR COUNSEL, Reminds Interface, Inc. Investors of Important Deadline in Securities Class Action – TILE

NEW YORK, Dec. 09, 2020 (GLOBE NEWSWIRE) — Rosen Law Firm, a global investor rights law firm, reminds purchasers of the securities of Interface, Inc. (NASDAQ: TILE) between March 2, 2018 and September 28, 2020, inclusive (the “Class Period”) of the important January 11, 2021 lead plaintiff deadline in the case. The lawsuit seeks to recover damages for Interface investors under the federal securities laws.

To join the Interface class action, go to http://www.rosenlegal.com/cases-register-1788.html or call Phillip Kim, Esq. toll-free at 866-767-3653 or email [email protected] or [email protected] for information on the class action.

According to the lawsuit, defendants throughout the Class Period made false and/or misleading statements and/or failed to disclose that: (1) Interface had inadequate disclosure controls and procedures and internal control over financial reporting; (2) consequently, Interface, among other things, reported artificially inflated income and earnings per share (EPS) in 2015 and 2016; (3) Interface and certain of its employees were under investigation by the SEC with respect to the foregoing since at least November 2017, had impeded the SEC’s investigation, and downplayed the true scope of Interface’s wrongdoing and liability with respect to the SEC investigation; and (4) as a result, defendants’ public statements were materially false and misleading at all relevant times. When the true details entered the market, the lawsuit claims that investors suffered damages.

A class action lawsuit has already been filed. If you wish to serve as lead plaintiff, you must move the Court no later than January 11, 2021. A lead plaintiff is a representative party acting on behalf of other class members in directing the litigation. If you wish to join the litigation, go to http://www.rosenlegal.com/cases-register-1788.html or to discuss your rights or interests regarding this class action, please contact Phillip Kim, Esq. of Rosen Law Firm toll free at 866-767-3653 or via e-mail at [email protected] or [email protected].

NO CLASS HAS YET BEEN CERTIFIED IN THE ABOVE ACTION. UNTIL A CLASS IS CERTIFIED, YOU ARE NOT REPRESENTED BY COUNSEL UNLESS YOU RETAIN ONE. YOU MAY RETAIN COUNSEL OF YOUR CHOICE. YOU MAY ALSO REMAIN AN ABSENT CLASS MEMBER AND DO NOTHING AT THIS POINT. AN INVESTOR’S ABILITY TO SHARE IN ANY POTENTIAL FUTURE RECOVERY IS NOT DEPENDENT UPON SERVING AS LEAD PLAINTIFF.

Follow us for updates on LinkedIn: https://www.linkedin.com/company/the-rosen-law-firm, on Twitter: https://twitter.com/rosen_firm or on Facebook: https://www.facebook.com/rosenlawfirm/.

Rosen Law Firm represents investors throughout the globe, concentrating its practice in securities class actions and shareholder derivative litigation. Rosen Law Firm was Ranked No. 1 by ISS Securities Class Action Services for number of securities class action settlements in 2017. The firm has been ranked in the top 3 each year since 2013. Rosen Law Firm has achieved the largest ever securities class action settlement against a Chinese Company. Rosen Law Firm’s attorneys are ranked and recognized by numerous independent and respected sources. Rosen Law Firm has secured hundreds of millions of dollars for investors. Attorney Advertising. Prior results do not guarantee a similar outcome.

Contact Information:

        Laurence Rosen, Esq.
        Phillip Kim, Esq.
        The Rosen Law Firm, P.A.
        275 Madison Avenue, 40th Floor
        New York, NY 10016
        Tel: (212) 686-1060
        Toll Free: (866) 767-3653
        Fax: (212) 202-3827
        [email protected]
        [email protected]
        [email protected]
        www.rosenlegal.com



Toll Brothers Announces Cash Dividend

FORT WASHINGTON, Pa., Dec. 09, 2020 (GLOBE NEWSWIRE) — Toll Brothers, Inc. (NYSE:TOL) (www.TollBrothers.com), the nation’s leading builder of luxury homes, today announced that its Board of Directors has approved a quarterly cash dividend to shareholders. The dividend of $0.11 per share will be paid on January 22, 2021 to shareholders of record on the close of business on January 8, 2021.

Toll Brothers, Inc., A FORTUNE 500 Company, is the nation’s leading builder of luxury homes. The Company began business over fifty years ago in 1967 and became a public company in 1986. Its common stock is listed on the New York Stock Exchange under the symbol “TOL.” The Company serves first-time, move-up, empty-nester, active-adult, affordable luxury and second-home buyers, as well as urban and suburban renters. It operates in 24 states: Arizona, California, Colorado, Connecticut, Delaware, Florida, Georgia, Idaho, Illinois, Maryland, Massachusetts, Michigan, Nevada, New Jersey, New York, North Carolina, Oregon, Pennsylvania, South Carolina, Tennessee, Texas, Utah, Virginia, and Washington, as well as in the District of Columbia.

Toll Brothers builds an array of luxury residential single-family detached, attached home, master planned resort-style golf, and urban low-, mid-, and high-rise communities, principally on land it develops and improves. The Company acquires and develops rental apartment and commercial properties through Toll Brothers Apartment Living, Toll Brothers Campus Living, and the affiliated Toll Brothers Realty Trust, and develops urban low-, mid-, and high-rise for-sale condominiums through Toll Brothers City Living. The Company operates its own architectural, engineering, mortgage, title, land development and land sale, golf course development and management, and landscape subsidiaries. Toll Brothers operates its own alarm monitoring company through TBI Smart Home Solutions, a complete home technology division. In addition to providing security monitoring, TBI Smart Home Solutions offers homeowners a full range of low voltage options, allowing buyers to maximize the potential of technology in their new home. The Company also operates its own lumber distribution, house component assembly, and manufacturing operations. Through its Gibraltar Real Estate Capital joint venture, the Company provides builders and developers with land banking, non-recourse debt and equity capital.

In 2020, Toll Brothers was named World’s Most Admired Home Building Company in Fortune magazine’s survey of the World’s Most Admired Companies®, the sixth year in a row it has been so honored. Toll Brothers has won numerous other awards, including Builder of the Year from both Professional Builder magazine and Builder magazine, the first two-time recipient from Builder magazine. The Company sponsors the Toll Brothers Metropolitan Opera International Radio Network, bringing opera to neighborhoods throughout the world. For more information visit www.TollBrothers.com.

Toll Brothers discloses information about its business and financial performance and other matters, and provides links to its securities filings, notices of investor events, and earnings and other news releases, on the Investor Relations section of its website (investors.TollBrothers.com).


Forward-Looking Statements

This release contains or may contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. One can identify these statements by the fact that they do not relate to matters of a strictly historical or factual nature and generally discuss or relate to future events. These statements contain words such as “anticipate,” “estimate,” “expect,” “project,” “intend,” “plan,” “believe,” “may,” “can,” “could,” “might,” “should,” “likely,” “will,” and other words or phrases of similar meaning. Such statements may include, but are not limited to, information and statements regarding: the impact of Covid-19 on the U.S. economy, the markets in which we operate or may operate, and on our business; our strategic priorities; our land acquisition, land development and capital allocation priorities; market conditions; demand for our homes; anticipated operating results and guidance; home deliveries; financial resources and condition; changes in revenues; changes in profitability; changes in margins; changes in accounting treatment; cost of revenues, including expected labor and material costs; selling, general, and administrative expenses; interest expense; inventory write-downs; home warranty and construction defect claims; unrecognized tax benefits; anticipated tax refunds; sales paces and prices; effects of home buyer cancellations; growth and expansion; joint ventures in which we are involved; anticipated results from our investments in unconsolidated entities; our ability to acquire or dispose of land and pursue real estate opportunities; our ability to gain approvals and open new communities; our ability to market, construct and sell homes and properties; our ability to deliver homes from backlog; our ability to secure materials and subcontractors; our ability to produce the liquidity and capital necessary to conduct normal business operations or to expand and take advantage of opportunities; and the outcome of legal proceedings, investigations, and claims.

Any or all of the forward-looking statements included in this release are not guarantees of future performance and may turn out to be inaccurate. This can occur as a result of incorrect assumptions or as a consequence of known or unknown risks and uncertainties. The major risks and uncertainties – and assumptions that are made – that affect our business and may cause actual results to differ from these forward-looking statements include, but are not limited to:

  • the effects of the ongoing Covid-19 pandemic, which are highly uncertain, cannot be predicted and will depend upon future developments, including the severity of Covid-19 and the duration of the outbreak, the duration of existing social distancing and shelter-in-place orders, further mitigation strategies taken by applicable government authorities, the availability of a vaccine, adequate testing and therapeutic treatments and the prevalence of widespread immunity to Covid-19;
  • the effect of general economic conditions, including employment rates, housing starts, interest rate levels, availability of financing for home mortgages and strength of the U.S. dollar;
  • market demand for our products, which is related to the strength of the various U.S. business segments and U.S. and international economic conditions;
  • the availability of desirable and reasonably priced land and our ability to control, purchase, hold and develop such parcels;
  • access to adequate capital on acceptable terms;
  • geographic concentration of our operations;
  • levels of competition;
  • raw material and labor prices and availability;
  • the effect of U.S. trade policies, including the imposition of tariffs and duties on home building products and retaliatory measures taken by other countries;
  • the effects of weather and the risk of loss from earthquakes, volcanoes, fires, floods, droughts, windstorms, hurricanes, pest infestations and other natural disasters, and the risk of delays, reduced consumer demand, and shortages and price increases in labor or materials associated with such natural disasters;
  • the risk of loss from acts of war, terrorism or outbreaks of contagious diseases, such as Covid-19;
  • transportation costs;
  • federal and state tax policies;
  • the effect of land use, environment and other governmental laws and regulations;
  • legal proceedings or disputes and the adequacy of reserves;
  • risks relating to any unforeseen changes to or effects on liabilities, future capital expenditures, revenues, expenses, earnings, indebtedness, financial condition, losses and future prospects;
  • changes in accounting principles;
  • risks related to unauthorized access to our computer systems, theft of our homebuyers’ confidential information or other forms of cyber-attack; and
  • other factors described in “Risk Factors” included in our Annual Report on Form 10-K for the year ended October 31, 2019 and in subsequent filings we make with the Securities and Exchange Commission (“SEC”).

Many of the factors mentioned above or in other reports or public statements made by us will be important in determining our future performance. Consequently, actual results may differ materially from those that might be anticipated from our forward-looking statements.

Forward-looking statements speak only as of the date they are made. We undertake no obligation to publicly update any forward-looking statements, whether as a result of new information, future events, or otherwise.

For a more detailed discussion of these factors, see the information under the captions “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” in our most recent Annual Report on Form 10-K filed with the SEC and in subsequent reports filed with the SEC.

CONTACT: Frederick N. Cooper (215) 938-8312
[email protected]

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/d33a542c-616e-4cb1-bf93-bc30cbc7fd11



Immutep Reports Statistically Significant Survival Benefit for Key Patient Groups in the Ongoing Phase IIb AIPAC Study in Metastatic Breast Cancer

  • First time an antigen presenting cell (APC) activator has shown an Overall Survival (OS) benefit in a randomised setting in metastatic breast cancer patients known to be insensitive to immune checkpoint inhibitor therapy
  • Promising and improving overall trend in OS in total population (based on approx. 60% of events): median survival benefit of +2.7 months from efti plus chemotherapy, compared to chemotherapy plus placebo
  • Statistically significant OS benefit in efti group observed in pre-defined patient groups:
    • +7.1 months survival benefit (median of 21.9 vs. 14.8 months, nearly 50% longer) from efti with chemotherapy for patients under 65 years of age
    • +9.4 months survival benefit (median of 22.4 vs. 12.9 months, 74% longer) from efti with chemotherapy for patients with a low starting monocyte count
  • Statistically significant increase in CD8 T cells in patients treated with efti plus chemotherapy, correlated with prolonged OS, indicating pharmacodynamic activity and proof of concept of efti’s mode of action 
  • Collection of OS data ongoing, with final data expected to be reported mid 2021
  • Investor webcast to discuss survival data scheduled for Friday, 11 December 2020, at 8.30 am Australian Eastern Daylight Time, details below

Sydney, AUSTRALIA, Dec. 10, 2020 (GLOBE NEWSWIRE) — Immutep Limited (ASX: IMM; NASDAQ: IMMP) a biotechnology company developing novel immunotherapy treatments for cancer and autoimmune disease, is pleased to report encouraging first Overall Survival (OS) follow up data from its ongoing Phase IIb AIPAC study evaluating Immutep’s lead product candidate eftilagimod alpha in combination with paclitaxel chemotherapy (“efti group”) in comparison to a combination of placebo and paclitaxel chemotherapy (“comparator group”) in patients with HER2-negative/HR positive metastatic breast cancer (HR+ MBC). These data were selected to be presented in a spotlight presentation at the San Antonio Breast Cancer Symposium 2020, which is being held virtually this week from Texas, USA.

AIPAC Principal Investigator, Hans Wildiers of University Hospital Leuven, Leuven, Belgium, said: 
“Improving Overall Survival is a key endpoint when evaluating the benefit of new anticancer drugs. Efti is a new drug targeting the immune system in an innovative way and has the potential to improve outcomes in HER2-negative/hormone receptor positive metastatic breast cancer patients. The AIPAC study investigated efti in combination with first line chemotherapy in this population, a group of about 250,000 patients diagnosed worldwide each year. Although the progression free survival data in the efti group did not show a significant improvement versus the comparator arm in AIPAC earlier this year, the OS data in general looks already very interesting and will mature further. The OS data in subgroups such as those below age 65 years are highly encouraging and may lead to more effective treatment options for metastatic breast cancer patients.”

Immutep CSO and CMO, Dr Frederic Triebel said: “We are very excited to see that efti is boosting the immune system by providing a statistically significant increase in CD8 T cell numbers, which is correlated with prolonged survival for patients. These data provide proof-of-concept and support our long-held belief that efti can provide a meaningful benefit to patients in a range of cancer settings by “pushing the gas” on the body’s immune system, representing an important landmark. Through this mechanism, efti is helping a large proportion of patients in the AIPAC study with Her2HR+ metastatic breast cancer which is typically a non-immunogenic cancer and is therefore significantly less responsive to modern immune checkpoint inhibitor (ICI) therapies. As such, chemotherapy continues to be the standard of care in many instances and there continues to be a large unmet medical need. We look forward to reporting final survival data in 2021.”

Immutep CEO, Marc Voigt said: “AIPAC marks an important milestone for Immutep and builds our confidence that efti is beneficial for many cancer patients, including those with metastatic breast cancer. Notably, we have seen a more material OS benefit than PFS benefit in this study; however, we note that this is not unusual for some immunotherapies where it can take time for the body’s immune system to be boosted and provide a therapeutic benefit. We are very encouraged by these first OS results which, subject to ongoing data collection, warrant a registrational perspective and regulatory interactions towards what we hope will be an important new class of medicines.”

Key Efficacy Results: data cut-off 24 September 2020

In the total patient population, first OS data (based on approx. 60% of events) show that patients in the efti group had an improving OS trend with a median OS of 20.2 months compared to 17.5 months for patients in the comparator group, indicating a survival benefit of +2.7 months (HR = 0.83; p = 0.14). The OS analysis is based on a 2-sided false positive probability of 0.05. Furthermore, a significant deterioration in quality of life was observed for patients in the comparator group at week 25, which was not observed in the efti group. This is an encouraging observation as these types of benefits are supportive of efti being eligible for reimbursement upon marketing approval.

In key predefined patient groups, the study has already demonstrated a statistically significant and clinically relevant OS benefit from treatment with efti in combination with chemotherapy. Patients under the age of 65 years (representing 66.7% of patients in the efti group) reported a median OS of 21.9 months compared to 14.8 months in the comparator group, indicating a survival benefit of +7.1 months (HR = 0.62; p = 0.012) favoring the efti group.

Figure 1 – Kaplan Meyer curve OS for patients < 65 years

The current data suggest that for patients younger than 65 years old, the probability of being alive at three years with efti plus chemotherapy vs. chemotherapy alone is increased by 100%.

Furthermore, patients with a low monocyte count at baseline (representing 21.9% of patients in the efti group) reported a median OS of 22.4 months compared to 12.9 months in the comparator group, indicating a survival benefit of +9.4 months (HR = 0.47; p = 0.02) favoring the efti group.

Trending towards statistical significance, patients with a more aggressive, more immunogenic luminal B type of breast cancer (representing 48.8% of patients in the efti group) reported a median OS of 16.3 months compared to 12.6 months in the comparator group, indicating a beneficial trend of +3.8 months (HR = 0.69; p = 0.077) favoring the efti group. (See Table 1)

Table 1 – Overall Survival in key patient groups

Group % of patients in efti group Efti group /

Comparator group
Median OS

(months)
Absolute OS benefit from efti
Total Population 100 % Efti + paclitaxel 20.2 +2.7 months

HR = 0.83
p = 0.14
Placebo + paclitaxel 17.5
< 65 years old 66.7 % Efti + paclitaxel 21.9 +7.1 months

HR = 0.62
p = 0.012
Placebo + paclitaxel 14.8
Low monocytes

< 0.25/nl
21.9 % Efti + paclitaxel 22.4 +9.4 months

HR = 0.47
p = 0.02
Placebo + paclitaxel 12.9
Luminal B 48.8 % Efti + paclitaxel 16.3 +3.8 months

HR = 0.69
p = 0.077
Placebo + paclitaxel 12.6

Note: A lower HR, means a reduced risk of death, e.g. by 53% in the low monocyte group.

Immuno Monitoring Results

Importantly, there was a statistically significant, sustained long-term increase in peripheral CD8 T cells in patients in the efti group. This is consistent with the mode of action of efti. There was also a statistically significant correlation between those patients having an increase in the number of CD8 T cells and those having a prolonged OS. This represents a strong proof-of-concept in a randomised, double blinded setting.

Safety

The combination of efti and paclitaxel chemotherapy was overall safe and well tolerated, further building upon efti’s strong safety profile to date.

The presentation poster is available at www.immutep.com/investors-media/presentations.html.

Next Steps

Multivariate analysis of the data is ongoing and final OS data is expected to be reported in mid 2021.

Webcast Details

Immutep will present this AIPAC data in a global webcast for investors, details are as follows:

  • Date & Time:     Friday, 11 December 2020, at 8.30 am Australian Eastern Daylight Time (AEDT) (Thursday, December 10th, at 4:30 p.m. U.S. ET)
  • Register:             http://public.viavid.com/index.php?id=142664
  • Questions:         Investors are invited to submit questions in advance via [email protected].

A replay of the webcast will also be available at www.immutep.com from the day after the event.

About the AIPAC trial

Active Immunotherapy Paclitaxel (AIPAC) is a multicentre, placebo-controlled, double-blind, 1:1 randomised Phase IIb clinical trial in HER2-negative/HR positive metastatic breast cancer.

The study is evaluating the combination of Immutep’s lead product candidate, eftilagimod alpha (efti, LAG-3Ig or IMP321), and paclitaxel chemotherapy. 227 HER2-negative/HR positive metastatic breast cancer patients are randomised 1:1 to a chemo-immunotherapy arm (efti plus paclitaxel) or to a comparator arm (placebo plus paclitaxel). Patients receive weekly paclitaxel at days 1, 8 and 15, with either efti or placebo injected subcutaneously on days 2 and 16 of each 4-week cycle, repeated for 6 cycles. Thereafter, patients pass over to the maintenance phase with efti alone.

For more information regarding the AIPAC trial, visit clinicaltrials.gov (identifier NCT02614833) and https://www.ncbi.nlm.nih.gov/pubmed/30977393).

About Immutep

Immutep is a globally active biotechnology company that is a leader in the development of LAG-3 related immunotherapeutic products for the treatment of cancer and autoimmune disease. Immutep is dedicated to leveraging its technology and expertise to bring innovative treatment options to market for patients and to maximize value to shareholders. Immutep is listed on the Australian Securities Exchange (IMM), and on the NASDAQ (IMMP) in the United States.

Immutep’s current lead product candidate is eftilagimod alpha (“efti” or “IMP321”), a soluble LAG-3 fusion protein (LAG-3Ig), which is a first-in-class antigen presenting cell (APC) activator being explored in cancer and infectious disease. Immutep is also developing an agonist of LAG-3 (IMP761) for autoimmune disease. Additional LAG-3 products, including antibodies for immune response modulation, are being developed by Immutep’s large pharmaceutical partners.

Further information can be found on the Company’s website www.immutep.com or by contacting:

Australian Investors/Media:

Catherine Strong, Citadel-MAGNUS
+61 (0)406 759 268; [email protected]



U.S. Media:

Tim McCarthy, LifeSci Advisors
+1 (212) 915.2564; [email protected]



Leading Edge Jet Center Brings Sustainable Aviation Fuel to BFI

Innovation in sustainable air transportation lands at King County International Airport-Boeing Field

SEATTLE, Dec. 09, 2020 (GLOBE NEWSWIRE) — Leading Edge Jet Center (“LEJC”), a provider of business aviation services throughout the Pacific Northwest, today announced the introduction of Sustainable Aviation Fuel (“SAF”) to its Fixed Base Operator (“FBO”) facility (“LEJC BFI”) at the King County International Airport-Boeing Field (“BFI”) in Seattle, Washington, one of the busiest general aviation airports in the United States, in partnership with Avfuel, a leading supplier of aviation fuel and services globally.

“We are proud to be a first mover in offering sustainable aviation fuel at BFI, contributing to Seattle’s goal of reducing total greenhouse gas emissions 58% by 2030, said Steven Levesque, Leading Edge Jet Center’s Executive Chairman. “Leading Edge Jet Center provides customers with outstanding service, convenient facilities, seamless transportation, quality maintenance and now direct access to more sustainable air travel.”

LEJC BFI was established in September 2020 with the acquisition of Kenmore Aero Services LLC, which now operates under the LEJC brand and vision for quality, service and innovation in business aviation. With this latest initiative, LEJC is positioning BFI as the first FBO in the state of Washington to offer the green alternative. Together, LEJC and Avfuel will provide customers with an approximately 7,300-gallon load of blended sustainable aviation fuel. SAF is estimated to have an 80% lower carbon footprint than conventional jet fuel, making it an important part of the aviation sector’s long-term strategy to reduce its greenhouse gas emissions.

Scott Helms, LEJC BFI’s General Manager, added, “We are delighted to provide our growing customer base with a high quality, green alternative to traditional jet fuel and to help advance the U.S. aviation industry’s environmental stewardship.”

At BFI, LEJC offers approximately 60,000 square feet of Class A hangar space alongside best-in-class aviation ground services for customers and their aircraft and is developing a new executive terminal and hangar facilities to meet growing demand. Founded in 2005 and established as a standalone company in 2019, LEJC also provides business aviation and jet fueling services at the Redmond Roberts Field Airport and Bend Municipal Airport in Central Oregon and is seeking opportunities to expand its platform in other regional hubs.

“We’re proud to work with Leading Edge Jet Center to make sustainable aviation fuel available to our airport users,” said John Parrott, director of King County International Airport-Boeing Field. “It’s a small but significant step toward supporting King County’s Strategic Climate Action Plan.”

About Leading Edge Jet Center

Leading Edge Jet Center delivers world-class business aviation and jet fueling services in the Pacific Northwest with bespoke customer care that focuses on providing a seamless travel experience. Offering a range of amenities from aircraft maintenance and storage, to ground transportation and hotel bookings, our passion for elevating the travel experience fuels a deep commitment to our clients and our communities. As a trusted aviation partner, Leading Edge Jet Center prides itself on delivering safe, comfortable and reliable service in all facets of our operations as we enable our customers and their businesses to soar to new heights. For more information on Leading Edge Jet Center’s Oregon facilities, please visit www.LeadingEdgeJet.com, or follow us on LinkedIn to receive all the latest updates.

Contact
:

Steven Levesque, Executive Chairman
Leading Edge Jet Center
(843) 412-6881
[email protected] 



Dr. Rui Feng Donates 80,000 New Pacific Shares to St. Paul’s Foundation in Vancouver and 35,000 New Pacific Shares to the Viola Desmond Chair in Social Justice, Cape Breton University

VANCOUVER, British Columbia, Dec. 09, 2020 (GLOBE NEWSWIRE) — New Pacific Metals Corp. (“New Pacific” or the “Company”) is pleased to announce that Dr. Rui Feng, founder, director and former CEO of the Company, has donated 80,000 shares of the Company to St. Paul’s Foundation of Vancouver and 35,000 shares of the Company to the Viola Desmond Chair in Social Justice at Cape Breton University in Nova Scotia.

St. Paul’s Foundation

Teams at St. Paul’s Hospital are undertaking high-impact COVID-19 research to understand the unprecedented variety of complications; and severe and lasting consequences for a patient’s lungs, heart, kidneys, brain, nervous system, and psychiatric health. This research is key to informing immediate patient care for the best possible health outcomes.

In recent months, St. Paul’s Hospital in Vancouver has been leading research efforts in Canada for better understanding the long-term effects of COVID-19. In May 2020, after just one month of planning and logistics, St. Paul’s launched its post-COVID respiratory clinic and research program.  By September, the clinic encompassed a team of specialists working together across disciplines to address the full scope of post-COVID illness.

“Life-saving research into COVID-19 at St. Paul’s Hospital will have a national impact,” says Dick Vollet, President and CEO, St. Paul’s Foundation. “This generous gift from Dr. Feng will support continued research and innovation to help find more efficient ways to treat the virus and ultimately improve the quality of life for our patients.”

The Viola Desmond Chair in Social Justice

Viola Desmond’s remarkable stand against racial segregation in 1946 is a story which has become an inspiration to all Canadians. In November 2018, Desmond made history by becoming the first Canadian female to appear on the Canadian $10 bill, cementing herself as a symbol of courage to Canadians everywhere.

The Viola Desmond Chair in Social Justice at Cape Breton University (“CBU”) will honour the legacy of Desmond through research and educational initiatives promoting social justice and African Canadian studies in Canada.

“On behalf of the Board of Governors, faculty, staff and students at Cape Breton University, I would like to extend our deepest thanks and gratitude to Dr. Feng for his generous support of our Viola Desmond Chair in Social Justice at CBU,” says President & Vice-Chancellor, David Dingwall. “Through the work of this Chair, we will continue to honour the legacy of social rights activist, Viola Desmond, through education, research and the promotion of social justice and African Canadian studies in Canada.”

ABOUT NEW PACIFIC

New Pacific is a Canadian exploration and development company which owns the Silver Sand Project, in the Potosi Department of Bolivia and the Silverstrike Project in Bolivia.

For further information,
please
contact:

New Pacific Metals Corp.
Gordon Neal
President
Phone: (604) 633-1368
Fax: (604) 669-9387
[email protected]
www.newpacificmetals.com



North Dallas Bank & Trust Co. Declares Regular Dividend of $0.25 Per Share And Special Dividend of $0.30 Per Share

DALLAS, Dec. 09, 2020 (GLOBE NEWSWIRE) — On December 8, 2020 the North Dallas Bank & Trust Co. (NODB) Board of Directors declared a regular dividend of $0.25 per share and a special dividend of $0.30 per share. The dividends are payable to shareholders of record as of December 23, 2020 and will be paid on December 31, 2020.

North Dallas Bank & Trust Co. is an independent bank established in 1961 with current locations in 5 locations in the Dallas, Texas area. The current dividends are based on North Dallas Bank & Trust Co.’s current financial condition and are not a guarantee that dividends will continue to be paid in the future. For further information about North Dallas Bank & Trust Co., contact Glenn Henry, Chief Financial Officer.

Assets $1.4 Billion

Contact:
Glenn Henry, EVP and CFO
972.716.7100



Puma Biotechnology Presents Updated Results from the Phase II SUMMIT Trial of Neratinib for HER2-Mutant, HR-Positive Metastatic Breast Cancer at SABCS 2020

Puma Biotechnology Presents Updated Results from the Phase II SUMMIT Trial of Neratinib for HER2-Mutant, HR-Positive Metastatic Breast Cancer at SABCS 2020

LOS ANGELES–(BUSINESS WIRE)–
Puma Biotechnology, Inc. (Nasdaq: PBYI), a biopharmaceutical company, presented updated results from the ongoing Phase II SUMMIT trial of neratinib at the 2020 Virtual San Antonio Breast Cancer Symposium (SABCS) that is currently taking place. The presentation entitled, “Latest findings from the breast cancer cohort in SUMMIT – a phase 2 ‘basket’ trial of neratinib + trastuzumab + fulvestrant for HER2-mutant, hormone receptor-positive, metastatic breast cancer,” is being presented at a Spotlight Poster Discussion Session by Komal Jhaveri, M.D., FACP, Memorial Sloan Kettering Cancer Center, an investigator of the trial. A copy of this poster presentation is available on the Puma website.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20201209005093/en/

The Phase II SUMMIT basket trial is an open-label, multicenter, multinational study to evaluate the safety and efficacy of neratinib administered daily to patients who have solid tumors with activating HER2 (ERBB2) or lung cancers with EGFR exon 18 mutations (NCT01953926). In the HER2-mutant, hormone receptor (HR)-positive breast cancer cohort, 51 patients received 240 mg of neratinib daily in combination with trastuzumab and fulvestrant. In this cohort, patients had received a median of 4 prior lines of therapy in the metastatic setting (range 1-10 prior regimens) before entering the trial. 36 patients (70.6%) had received prior fulvestrant, 35 patients (68.6%) had received prior aromatase inhibitor and 4 patients (7.8%) had received prior tamoxifen. Further, 30 patients (58.8%) received prior cyclin-dependent kinase 4/6-inhibitor (CDK4/6i) therapy. Thirty-five patients (68.6%) had received prior chemotherapy.

The interim efficacy summary of the breast cohort that received neratinib in combination with trastuzumab and fulvestrant showed that for the 37 RECIST efficacy evaluable patients, 17 patients (45.9%) experienced a confirmed objective response, including one complete response (2.7%) and 16 (43.2%) partial responses, and 20 patients (54.1%) experienced clinical benefit (clinical benefit is defined as confirmed complete response or partial response or stable disease for at least 24 weeks). The median duration of response was 10.9 months and the median progression-free survival was 8.3 months.

The safety profile observed in patients treated with the combination of neratinib plus trastuzumab plus fulvestrant in the SUMMIT study was consistent with that observed previously in metastatic patients with HER2 amplified tumors. All patients received anti-diarrheal prophylaxis with loperamide alone. The interim safety results of the study showed that the most frequently observed adverse event was diarrhea. For the 51 safety evaluable patients enrolled in this cohort, 20 patients (39.2%) reported grade 3 diarrhea. The median duration of grade 3 diarrhea for those patients was 6 days. No patient permanently discontinued neratinib due to diarrhea.

Komal Jhaveri, M.D., FACP, Memorial Sloan Kettering Cancer Center, Clinical Director of the Early Drug Development Service and Assistant Professor of Medicine, Weill Cornell Medical College, said, “HER2 mutations appear to be oncogenic drivers in a subset of metastatic breast cancers and are clinically actionable. The combination of neratinib + trastuzumab + fulvestrant therapy demonstrates encouraging clinical activity with durable responses in this molecular-defined patient population with clinical benefit observed in patients who have previously been treated after standard of care CDK4/6i and endocrine therapies.”

Alan H. Auerbach, CEO and President of Puma Biotechnology, added, “We are pleased to see that the combination of neratinib + fulvestrant + trastuzumab continues to demonstrate encouraging clinical activity in this heavily pre-treated cohort. We are continuing to enroll the randomized cohorts in the SUMMIT trial of neratinib in hormone receptor positive breast cancer patients with HER2 mutations and we anticipate the completion of this enrollment in the first half of 2021.”

About Puma Biotechnology

Puma Biotechnology, Inc. is a biopharmaceutical company with a focus on the development and commercialization of innovative products to enhance cancer care. Puma in-licenses the global development and commercialization rights to PB272 (neratinib, oral), PB272 (neratinib, intravenous) and PB357. Neratinib, oral was approved by the U.S. Food and Drug Administration in 2017 for the extended adjuvant treatment of adult patients with early stage HER2-overexpressed/amplified breast cancer, following adjuvant trastuzumab-based therapy, and is marketed in the United States as NERLYNX® (neratinib) tablets. In February 2020, NERLYNX was also approved by the FDA in combination with capecitabine for the treatment of adult patients with advanced or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting. NERLYNX was granted marketing authorization by the European Commission in 2018 for the extended adjuvant treatment of adult patients with early stage hormone receptor-positive HER2-overexpressed/amplified breast cancer and who are less than one year from completion of prior adjuvant trastuzumab-based therapy. NERLYNX is a registered trademark of Puma Biotechnology, Inc.

Further information about Puma Biotechnology may be found at www.pumabiotechnology.com.

IMPORTANT SAFETY INFORMATION

NERLYNX® (neratinib) tablets, for oral use

INDICATIONS AND USAGE: NERLYNX is a kinase inhibitor indicated:

  • As a single agent, for the extended adjuvant treatment of adult patients with early-stage HER2-positive breast cancer, to follow adjuvant trastuzumab-based therapy.
  • In combination with capecitabine, for the treatment of adult patients with advanced or metastatic HER2-positive breast cancer, who have received two or more prior anti-HER2 based regimens in the metastatic setting.

CONTRAINDICATIONS: None

WARNINGS AND PRECAUTIONS:

  • Diarrhea: Aggressively manage diarrhea. If diarrhea occurs despite recommended prophylaxis, treat with additional antidiarrheals, fluids, and electrolytes as clinically indicated. Withhold NERLYNX in patients experiencing severe and/or persistent diarrhea. Permanently discontinue NERLYNX in patients experiencing Grade 4 diarrhea or Grade ≥ 2 diarrhea that occurs after maximal dose reduction.
  • Hepatotoxicity: Monitor liver function tests monthly for the first 3 months of treatment, then every 3 months while on treatment and as clinically indicated. Withhold NERLYNX in patients experiencing Grade 3 liver abnormalities and permanently discontinue NERLYNX in patients experiencing Grade 4 liver abnormalities.
  • Embryo-Fetal Toxicity: NERLYNX can cause fetal harm. Advise patients of potential risk to a fetus and to use effective contraception.

ADVERSE REACTIONS:

The most common adverse reactions (reported in ≥ 5% of patients) were as follows:

  • NERLYNX as a single agent: Diarrhea, nausea, abdominal pain, fatigue, vomiting, rash, stomatitis, decreased appetite, muscle spasms, dyspepsia, AST or ALT increased, nail disorder, dry skin, abdominal distention, epistaxis, weight decreased, and urinary tract infection.
  • NERLYNX in combination with capecitabine: Diarrhea, nausea, vomiting, decreased appetite, constipation, fatigue/asthenia, weight decreased, dizziness, back pain, arthralgia, urinary tract infection, upper respiratory tract infection, abdominal distention, renal impairment, and muscle spasms.

To report SUSPECTED ADVERSE REACTIONS, contact Puma Biotechnology, Inc. at 1-844-NERLYNX (1-844-637-5969) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

DRUG INTERACTIONS:

  • Gastric acid reducing agents: Avoid concomitant use with proton pump inhibitors. When patients require gastric acid reducing agents, use an H2-receptor antagonist or antacid. Separate NERLYNX by at least 3 hours with antacids. Separate NERLYNX by at least 2 hours before or 10 hours after H2-receptor antagonists.
  • Strong CYP3A4 inhibitors: Avoid concomitant use.
  • Moderate CYP3A4 and P-glycoprotein (P-gp) dual inhibitors: Avoid concomitant use.
  • Strong or moderate CYP3A4 inducers: Avoid concomitant use.
  • P-glycoprotein (P-gp) substrates: Monitor for adverse reactions of narrow therapeutic agents that are P-gp substrates when used concomitantly with NERLYNX.

USE IN SPECIFIC POPULATIONS:

  • Lactation: Advise women not to breastfeed.

Please see Full Prescribing Information for additional safety information.

To help ensure patients have access to NERLYNX, Puma has implemented the Puma Patient Lynx support program to assist patients and healthcare providers with reimbursement support and referrals to resources that can help with financial assistance. More information on the Puma Patient Lynx program can be found at www.NERLYNX.com or 1-855-816-5421.

Forward-Looking Statements

This press release contains forward-looking statements, including statements regarding the development of combinations involving neratinib. All forward-looking statements involve risks and uncertainties that could cause Puma’s actual results to differ materially from the anticipated results and expectations expressed in these forward-looking statements. These statements are based on current expectations, forecasts and assumptions, and actual outcomes and results could differ materially from these statements due to a number of factors, which include, but are not limited to, any adverse impact on Puma’s business or the global economy and financial markets, generally, from the global COVID-19 pandemic, and the risk factors disclosed in the periodic and current reports filed by Puma with the Securities and Exchange Commission from time to time, including Puma’s Annual Report on Form 10-K for the year ended December 31, 2019, Puma’s Quarterly Report on Form 10-Q for the quarter ended March 31, 2020, and subsequent reports. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. Puma assumes no obligation to update these forward-looking statements, except as required by law.

Alan H. Auerbach or Mariann Ohanesian, Puma Biotechnology, Inc., +1 424 248 6500

[email protected]

[email protected]

David Schull or Maggie Beller, Russo Partners, +1 212 845 4200

[email protected]

[email protected]

KEYWORDS: California United States North America

INDUSTRY KEYWORDS: Biotechnology Health Pharmaceutical Clinical Trials Oncology

MEDIA:

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Equitable announces two new board directors and intention to cancel backstop liquidity facility

Canada NewsWire

TORONTO, Dec. 9, 2020 /CNW/ – Equitable Group and its wholly owned subsidiary Equitable Bank (TSX: EQB) (EQB.PR.C) today announced the appointment of Diane Giard and Yongah Kim to its Board of Directors.

Ms. Giard is the former Executive Vice-President of National Bank and Senior Vice-President of Scotiabank. Diane has broad experience across all elements of commercial and personal banking, as well as in risk management. She lives in Quebec and is a director of both Bombardier Inc. and TFI International Inc.

Ms. Kim is an Associate Professor of Strategic Management at the Rotman School of Management. Previously, Yongah was a Senior Partner with McKinsey & Company, in Canada and Korea. Her main areas of focus include strategic change and implementation with an emphasis on digital transformations. She relocated from Seoul to Toronto in 2015 and is Vice-Chair of the Board of the Hospital for Sick Children.

“Diane brings with her a wealth of retail and digital banking, business-to-consumer, and marketing experience, while Yongah brings a global perspective coupled with deep expertise in financial institutions, including other challenger banks” said David LeGresley, Chair of the Board of Equitable Bank. “These valuable and diverse skills are welcome additions to our Board. Further, our diligent selection process not only assesses candidates against a detailed skills matrix, but also considers diversity in its many forms. On behalf of the Board and management of the Bank, it’s my great pleasure to welcome Diane and Yongah to Equitable.”

“Equitable benefits from a strong governance approach that supports and aligns with our ambition as Canada’s Challenger Bank,” said Andrew Moor, Chief Executive Officer of Equitable Bank. “Our executive team will undoubtedly benefit from Diane and Yongah’s insight and experience, which will add to the advice we already receive from our skilled Board, as we collectively build value for our shareholders, employees and customers.” 

Both positions are effective December 9, 2020.

Further to today’s Board of Directors announcement, the Bank has also announced that it has given notice to permanently reduce its $400 million secured backstop liquidity facility effective December 11th, and intends to terminate the facility immediately thereafter.  This withdrawal signals ongoing confidence in the Bank’s liquidity, as well as its strong position for continued growth.

About Equitable Group Inc.

Equitable Group Inc. is a growing Canadian financial services business that operates through its wholly owned subsidiary, Equitable Bank. Equitable Bank, Canada’s Challenger BankTM, has grown to become the country’s ninth largest independent Schedule I bank through its proven branchless approach and customer service focus in providing residential lending, commercial lending, wealth management, and savings solutions to Canadian consumers and investors. EQ Bank, the digital banking platform offered by Equitable Bank, provides state-of-the-art digital banking services. Equitable Bank is a member of Canada Deposit Insurance Corporation (CDIC) and employs over 900 dedicated professionals across the country. For more information about Equitable Bank and its products, please visit equitablebank.ca.

SOURCE Equitable Group Inc.

Redfin to Present at Piper Sandler P.S. It’s Friday Series: The Future of Home & Housing

PR Newswire

SEATTLE, Dec. 9, 2020 /PRNewswire/ — Redfin Corporation (NASDAQ: RDFN) today announced that Chief Financial Officer Chris Nielsen will present at the following virtual event:

Piper Sandler P.S. It’s Friday Series: The Future of Home & Housing
Friday, December 11, at 11:00 a.m. ET

Link to the live webcast, as well as the replay, will be available at http://investors.redfin.com

About Redfin
Redfin (www.redfin.com) is a technology-powered residential real estate company, redefining real estate in the consumer’s favor in a commission-driven industry. We do this by integrating every step of the home buying and selling process and pairing our own agents with our own technology, creating a service that is faster, better and costs less. We offer brokerage, iBuying, mortgage, and title services, and we also run the country’s #1 real estate brokerage search site, offering a host of online tools to consumers, including the Redfin Estimate. We represent people buying and selling homes in over 90 markets in the United States and Canada. Since our launch in 2006, we have saved our customers over $800 million and we’ve helped them buy or sell more than 235,000 homes worth more than $115 billion.

Redfin-F

 

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SOURCE Redfin

Pixelworks Announces Proposed Public Offering of Common Stock

PR Newswire

SAN JOSE, Calif., Dec. 9, 2020 /PRNewswire/ — Pixelworks, Inc. (Nasdaq: PXLW) today announced that it intends to offer shares of its common stock for sale in an underwritten public offering. All of the shares in the offering are being offered by Pixelworks. The offering is subject to market and other conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.

Roth Capital Partners and Craig-Hallum Capital Group are acting as joint book-running managers for the offering.

A shelf registration statement relating to the shares was previously filed with the Securities and Exchange Commission (the “SEC”) and became effective on November 16, 2020. The offering will be made only by means of a written prospectus and prospectus supplement that form a part of the registration statement. Copies of the preliminary prospectus supplement and accompanying prospectus relating to the offering will be filed with the SEC and, when available, may be obtained by contacting Roth Capital Partners, 888 San Clemente, Newport Beach, CA 92660, Attn: Prospectus Department, telephone: 800-678-9147, or Craig-Hallum Capital Group, 222 South Ninth Street, Suite 350, Minneapolis, MN 55402, Attn: Equity Capital Markets, telephone: 612-334-6300 or by email at [email protected].

This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

About Pixelworks, Inc.

Pixelworks provides industry-leading content creation, video delivery and display processing solutions and technology that enable highly authentic viewing experiences with superior visual quality, across all screens – from cinema to smartphone and beyond. The Company has a 20-year history of delivering image processing innovation to leading providers of consumer electronics, professional displays, and video streaming services. Pixelworks is headquartered in San Jose, CA. For more information, please visit the Company’s web site at www.pixelworks.com.

Note: Pixelworks and the Pixelworks logo are registered trademarks of Pixelworks, Inc.

Safe Harbor Statement

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These statements may be identified by use of terms such as “will,” “expect,” “shall,” and similar terms or the negative of such terms, and include, without limitation, statements about the Company’s expectations regarding the completion, terms, size, and timing of the public offering, and with respect to granting the underwriters a 30-day option to purchase additional shares.  Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Factors that may cause such a difference include risks and uncertainties related to completion of the public offering on the anticipated terms or at all, market conditions and the satisfaction of customary closing conditions related to the public offering. More information about the risks and uncertainties faced by Pixelworks is contained in the section captioned “Risk Factors” in the prospectus supplement related to the public offering and from time to time in the Company’s Securities and Exchange Commission filings, including its Annual Report on Form 10-K for the year ended December 31, 2019, its Quarterly Report on Form 10-Q for the quarter ended September 30, 2020, as well as subsequent SEC filings. The forward-looking statements contained in this release are as of the date of this release, and the Company does not undertake any obligation to update any such statements, whether as a result of new information, future events or otherwise.

 

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SOURCE Pixelworks, Inc.