Amylyx Pharmaceuticals Announces First Participant Dosed in Phase 1, Multiple Ascending Dose LUMINA Trial of AMX0114 in People Living with Amyotrophic Lateral Sclerosis

Amylyx Pharmaceuticals Announces First Participant Dosed in Phase 1, Multiple Ascending Dose LUMINA Trial of AMX0114 in People Living with Amyotrophic Lateral Sclerosis

Amylyx expects early cohort data from LUMINA this year

AMX0114 is an Amylyx-developed antisense oligonucleotide designed to target calpain-2, a key contributor to the axonal degeneration pathway in ALS

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) (“Amylyx” or the “Company”) today announced that the first participant has been dosed in LUMINA, the Company’s Phase 1, multinational, randomized, double-blind, placebo-controlled, multiple ascending dose clinical trial of AMX0114, an investigational, potent antisense oligonucleotide (ASO) targeting calpain-2, in people living with amyotrophic lateral sclerosis (ALS). The Company continues to expect early cohort data from LUMINA in 2025.

The LUMINA trial (NCT06665165) will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of AMX0114 in people living with ALS. LUMINA will also assess broadly researched ALS biomarkers, including change from baseline in neurofilament light chain (NfL) levels. LUMINA is anticipated to enroll approximately 48 people living with ALS across North America. Participants will be randomized 3:1 to receive AMX0114 or placebo by intrathecal administration once every four weeks for a total of up to 4 doses.

“AMX0114 targets calpain-2, which has been found to be an important contributor to axonal degeneration and studied over decades of research as a potential target for the treatment of ALS and other neurodegenerative diseases. In preclinical studies, AMX0114 showed improved neuronal survival and reductions in extracellular NfL levels across multiple disease models. We are excited to progress AMX0114 into the clinic for people with ALS as we work to advance a potential therapy for this relentlessly progressive, fatal disease,” said Camille L. Bedrosian, MD, Chief Medical Officer at Amylyx.

Amylyx designed AMX0114 to target calpain-2, a calcium-activated protease. Peer-reviewed research has demonstrated that overactive calpain-2 activity may be an important driver of disease progression in ALS and other neurodegenerative diseases by executing the degeneration of axons, the long tubular neuronal segments which carry signals from neurons to the muscle or other neurons. Preclinical studies in ALS models suggest that the inhibition of calpain-2 may improve neuron survival and mitigate axonal degeneration.

“ALS is a devastating and fatal neurodegenerative disease with limited treatment options, underscoring the urgent need for new therapeutic approaches that target the underlying mechanisms driving ALS progression. AMX0114 represents a potential therapeutic approach to inhibiting one of the fundamental drivers of axonal degeneration,” said Sabrina Paganoni, MD, PhD, principal investigator of the LUMINA trial, investigator at the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital, and member of the Scientific Advisory Board of the Northeast Amyotrophic Lateral Sclerosis Consortium (NEALS). “Dosing the first participant in LUMINA is a step toward a potential treatment option for people living with ALS and their loved ones.”

More information about the LUMINA clinical trial can be found at www.clinicaltrials.gov, NCT06665165.

About AMX0114

AMX0114 is an investigational antisense oligonucleotide (ASO) targeting calpain-2 (CAPN2) for the potential treatment of ALS. In preclinical studies, treatment with AMX0114 resulted in potent, dose-dependent, and durable reduction in CAPN2 mRNA and calpain-2 protein levels in disease-relevant cell models of axonal degeneration. This translated to improved neuronal survival, including in a model of TDP-43 ALS, and reductions in extracellular neurofilament light (NfL) levels across multiple disease models and paradigms of neuronal injury. AMX0114 was well-tolerated in in vivo preclinical safety studies.

About LUMINA

The Phase 1 LUMINA clinical trial (NCT06665165) is a multinational, randomized, double-blind, placebo-controlled, multiple ascending dose trial evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of AMX0114 in people living with ALS. LUMINA is anticipated to enroll approximately 48 adult participants. LUMINA will also assess change from baseline in calpain-2 levels, neurofilament light (NfL) levels, and other pharmacodynamic biomarkers of ALS.

About ALS

Amyotrophic lateral sclerosis (ALS, also known as motor neuron disease) is a relentlessly progressive and fatal neurodegenerative disorder caused by motor neuron death in the brain and spinal cord. Motor neuron loss in ALS leads to deteriorating muscle function, the inability to move and speak, respiratory paralysis, and eventually, death. More than 90% of people with ALS have sporadic disease, showing no clear family history.

About Amylyx Pharmaceuticals

At Amylyx, our mission is to usher in a new era of treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are currently focused on three investigational therapies across several neurodegenerative and endocrine diseases in which we believe they can make the greatest impact. For more information, visit amylyx.com and follow us on LinkedIn and X. For investors, please visit investors.amylyx.com.

Forward-Looking Statements

Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, Amylyx’ expectations regarding: the potential for AMX0114 as a treatment for ALS and the expected timeline for data readout. Any forward-looking statements in this press release and related comments in the Company’s earnings conference call are based on management’s current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. Risks that contribute to the uncertain nature of the forward-looking statements include: the success, cost, and timing of Amylyx’ program development activities; Amylyx’ ability to execute on its regulatory development plans and expectations regarding the timing of results from its planned data announcements and initiation of clinical studies; the risk that early-stage results may not reflect later-stage results; Amylyx’ ability to fund operations, and the impact that global macroeconomic uncertainty, geopolitical instability, and public health events will have on Amylyx’ operations, as well as the risks and uncertainties set forth in Amylyx’ United States Securities and Exchange Commission (SEC) filings, including Amylyx’ Annual Report on Form 10-K for the year ended December 31, 2024, and subsequent filings with the SEC. All forward-looking statements contained in this press release and related comments in our earnings conference call speak only as of the date on which they were made. Amylyx undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as required by law.

Media

Amylyx Media Team

(857) 799-7274

[email protected]

Investors

Lindsey Allen

(857) 320-6244

[email protected]

KEYWORDS: United States North America Massachusetts

INDUSTRY KEYWORDS: Biotechnology Manufacturing Health Pharmaceutical Biometrics Neurology Research Other Manufacturing Genetics Science Clinical Trials

MEDIA:

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Glaukos to Release First Quarter 2025 Financial Results after Market Close on April 30

Glaukos to Release First Quarter 2025 Financial Results after Market Close on April 30

Conference Call and Webcast Scheduled for 1:30 p.m. PT

ALISO VIEJO, Calif.–(BUSINESS WIRE)–
Glaukos Corporation (NYSE: GKOS), an ophthalmic pharmaceutical and medical technology company focused on novel therapies for the treatment of glaucoma, corneal disorders and retinal diseases, plans to release first quarter 2025 financial results after the market close on Wednesday, April 30, 2025. The company’s management will discuss the results during a conference call and simultaneous webcast at 1:30 p.m. PT (4:30 p.m. ET) on April 30, 2025.

A link to the live webcast will be available on the company’s website at http://investors.glaukos.com. To participate in the conference call, please dial 800-715-9871 (U.S.) or 646-307-1963 (International) and enter Conference ID 5255602. A replay will be archived on the company’s website following completion of the call.

About Glaukos

Glaukos (www.glaukos.com) is an ophthalmic pharmaceutical and medical technology company focused on developing and commercializing novel therapies for the treatment of glaucoma, corneal disorders and retinal diseases. Glaukos first developed Micro-Invasive Glaucoma Surgery (MIGS) as an alternative to the traditional glaucoma treatment paradigm, launching its first MIGS device commercially in 2012. In 2024, Glaukos commenced commercial launch activities for iDose® TR, a first-of-its-kind, long-duration, intracameral procedural pharmaceutical designed to deliver 24/7 glaucoma drug therapy inside the eye for extended periods of time. Glaukos also markets the only FDA-approved corneal cross-linking therapy utilizing a proprietary bio-activated pharmaceutical for the treatment of keratoconus, a rare corneal disorder. Glaukos continues to successfully develop and advance a robust pipeline of novel, dropless platform technologies designed to meaningfully advance the standard of care and improve outcomes for patients suffering from chronic eye diseases.

Chris Lewis

Vice President, Investor Relations and Corporate Affairs

(949) 481-0510

[email protected]

KEYWORDS: United States North America California

INDUSTRY KEYWORDS: Surgery Medical Devices Health Pharmaceutical Optical

MEDIA:

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Littelfuse Announces CFO Transition Plan

Littelfuse Announces CFO Transition Plan

  • Meenal Sethna to step down as CFO
  • Company commences formal CFO search

CHICAGO–(BUSINESS WIRE)–
Littelfuse, Inc. (NASDAQ: LFUS), a diversified industrial technology manufacturing company empowering a sustainable, connected, and safer world, today announced that Meenal Sethna, Executive Vice President and Chief Financial Officer, will step down from her role after ten years of leadership. She will remain with the company through September 1, 2025, to ensure a smooth transition.

Dr. Greg Henderson, Littelfuse President & CEO, commented, “Since joining Littelfuse in 2015, Meenal’s leadership and contributions have been essential to the company’s growth and profitability expansion. As a result of her strategic guidance, Littelfuse is well positioned with the financial strength and flexibility to fuel the company’s next growth phase. I would like to thank Meenal for her unwavering commitment to Littelfuse, our global teams and our shareholders. I look forward to partnering with her during the transition, and we wish her well in her future endeavors.”

“It has been an honor to serve as Littelfuse CFO and collaborate with our outstanding leadership team,” Ms. Sethna said. “Littelfuse has exceptional people and I want to thank our talented and passionate team members around the world for all that we have accomplished together. With Littelfuse well positioned to deliver strong growth and profitability expansion going forward, I believe the time is right for me to transition to the next phase of my career.”

This leadership change is not the result of any matters relating to the Company’s financials, operations, policies or practices. Littelfuse has commenced a formal search to identify the Company’s next CFO.

About Littelfuse

Littelfuse, Inc. (NASDAQ: LFUS) is a diversified, industrial technology manufacturing company empowering a sustainable, connected, and safer world. Across more than 20 countries, and with approximately 16,000 global associates, we partner with customers to design and deliver innovative, reliable solutions. Serving over 100,000 end customers, our products are found in a variety of industrial, transportation, and electronics end markets–everywhere, every day. Learn more at Littelfuse.com.

LFUS-F

David Kelley

224-727-2535

[email protected]

KEYWORDS: United States North America Illinois

INDUSTRY KEYWORDS: Semiconductor Consumer Electronics Automotive Manufacturing Technology Manufacturing Mobile/Wireless

MEDIA:

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Triple Flag Announces Record Revenue from Strong Q1 2025 GEOs

Triple Flag Announces Record Revenue from Strong Q1 2025 GEOs

TORONTO–(BUSINESS WIRE)–
Triple Flag Precious Metals Corp. (with its subsidiaries, “Triple Flag” or the “Company”) (TSX: TFPM, NYSE: TFPM) announced record revenue of US$82.2 million for the first quarter of 2025 from quarterly metal sales of 28,761 gold equivalent ounces1 (“GEOs”). All dollar amounts are expressed in US dollars, unless otherwise noted.

“Our business achieved record revenue to start the year. Triple Flag is on track to deliver 2025 GEOs guidance of 105,000 to 115,000 ounces,” commented Sheldon Vanderkooy, CEO. “We are also pleased to have completed our acquisitions on the Arcata, Azuca and Tres Quebradas assets, representing near-term cash flow from long-life operations located in the Americas with significant exploration potential. Triple Flag is well-positioned to deliver per share growth in the strong precious metals price environment.”

Preliminary Q1 2025 GEOs Sold and Revenue

GEOs Sold and Revenue by Commodity2

Q1 2025

GEOs Sold

Revenue ($M)

Gold

21,944

62.7

Silver

6,817

19.5

Total

28,761

82.2

Conference Call Details

Triple Flag will release its Q1 2025 results on Tuesday, May 6, after market close.

A conference call and live webcast presentation will be held the following day, May 7, 2025, starting at 9:00 a.m. ET (6:00 a.m. PT) to discuss these results. The live webcast can be accessed by visiting the Events and Presentations page on the Company’s website at: www.tripleflagpm.com. An archived version of the webcast will be available on the website for one year following the webcast.

Live Webcast:

https://events.q4inc.com/attendee/271421749

 

Dial-In Details:

 

Toll-Free (U.S. & Canada): +1 (888) 330-2384

International: +1 (647) 800-3739

Conference ID: 4548984, followed by # key

 

Replay (Until May 21):

 

Toll-Free (U.S. & Canada): +1 (800) 770-2030

International: +1 (647) 362-9199

Conference ID: 4548984, followed by # key

About Triple Flag Precious Metals

Triple Flag is a precious metals streaming and royalty company. We offer investors exposure to gold and silver from a total of 236 assets, consisting of 17 streams and 219 royalties, primarily from the Americas and Australia. These streams and royalties are tied to mining assets at various stages of the mine life cycle, including 30 producing mines and 206 development and exploration stage projects. Triple Flag is listed on the Toronto Stock Exchange and New York Stock Exchange, under the ticker “TFPM”.

Qualified Person

James Lill, Director, Mining for Triple Flag Precious Metals and a “qualified person” under NI 43-101 has reviewed and approved the written scientific and technical disclosures contained in this press release.

Forward-Looking Information

This news release contains “forward-looking information” within the meaning of applicable Canadian securities laws and “forward-looking statements” within the meaning of the United States Private Securities Litigation Reform Act of 1995, respectively (collectively referred to herein as “forward-looking information”). Forward-looking information may be identified by the use of forward-looking terminology such as “plans”, “targets”, “expects”, “is expected”, “budget”, “scheduled”, “estimates”, “outlook”, “forecasts”, “projection”, “prospects”, “strategy”, “intends”, “anticipates”, “believes” or variations of such words and phrases or terminology which states that certain actions, events or results “may”, “could”, “would”, “might”, “will”, “will be taken”, “occur” or “be achieved”. Forward-looking information in this news release include, but are not limited to, statements with respect to the accounting treatments for certain of the Company’s streams, the Company’s preliminary sales and revenue information for the first quarter of 2025, the release of its financial results for the first quarter of 2025, and the conduct of the conference call to discuss said results. In addition, any statements that refer to expectations, intentions, projections or other characterizations of future events or circumstances contain forward-looking information. Statements containing forward-looking information are not historical facts but instead represent management’s expectations, estimates and projections regarding possible future events or circumstances.

The forward-looking information included in this news release is based on our opinions, estimates and assumptions in light of our experience and perception of historical trends, current conditions and expected future developments, as well as other factors that we currently believe are appropriate and reasonable in the circumstances. The forward-looking information contained in this news release is also based upon a number of assumptions, including the ongoing operation of the properties in which we hold a stream or royalty interest by the owners or operators of such properties in a manner consistent with past practice; the accuracy of public statements and disclosures made by the owners or operators of such underlying properties; and the accuracy of publicly disclosed expectations for the development of underlying properties that are not yet in production. These assumptions include, but are not limited to, the following: assumptions in respect of current and future market conditions and the execution of our business strategies; that operations, or ramp-up where applicable, at properties in which we hold a royalty, stream or other interest continue without further interruption through the period; and the absence of any other factors that could cause actions, events or results to differ from those anticipated, estimated, intended or implied. Despite a careful process to prepare and review the forward-looking information, there can be no assurance that the underlying opinions, estimates and assumptions will prove to be correct. Forward-looking information is also subject to known and unknown risks, uncertainties and other factors that may cause the actual results, level of activity, performance or achievements to be materially different from those expressed or implied by such forward-looking information. Such risks, uncertainties and other factors include, but are not limited to, those set forth under the caption “Risk and Risk Management” in our management’s discussion and analysis in respect of the fourth quarter and full year of 2024 and the caption “Risk Factors” in our most recently filed annual information form, each of which is available on SEDAR+ at www.sedarplus.ca and on EDGAR at www.sec.gov. In addition, we note that mineral resources that are not mineral reserves do not have demonstrated economic viability and inferred resources are considered too geologically speculative for the application of economic considerations.

Although we have attempted to identify important risk factors that could cause actual results or future events to differ materially from those contained in the forward-looking information, there may be other risk factors not presently known to us or that we presently believe are not material that could also cause actual results or future events to differ materially from those expressed in such forward-looking information. There can be no assurance that such information will prove to be accurate, as actual results and future events could differ materially from those anticipated in such information. Accordingly, readers should not place undue reliance on forward-looking information, which speaks only as of the date made. The forward-looking information contained in this news release represents our expectations as of the date of this news release and is subject to change after such date. We disclaim any intention or obligation or undertaking to update or revise any forward-looking information whether as a result of new information, future events or otherwise, except as required by applicable securities laws. All of the forward-looking information contained in this news release is expressly qualified by the foregoing cautionary statements.

Cautionary Statement to U.S. Investors

Information contained or referenced in this press release or in the documents referenced herein concerning the properties, technical information and operations of Triple Flag has been prepared in accordance with requirements and standards under Canadian securities laws, which differ from the requirements of the U.S. Securities and Exchange Commission (“SEC”) under subpart 1300 of Regulation S-K (“S-K 1300”). Because the Company is eligible for the Multijurisdictional Disclosure System adopted by the SEC and Canadian Securities Administrators, Triple Flag is not required to present disclosure regarding its mineral properties in compliance with S-K 1300. Accordingly, certain information contained in this press release may not be comparable to similar information made public by U.S. companies subject to reporting and disclosure requirements of the SEC.

Technical and Third-Party Information

Triple Flag does not own, develop or mine the underlying properties on which it holds stream or royalty interests. As a royalty or stream holder, Triple Flag has limited, if any, access to properties included in its asset portfolio. As a result, Triple Flag is dependent on the owners or operators of the properties and their qualified persons to provide information to Triple Flag and on publicly available information to prepare disclosure pertaining to properties and operations on the properties on which Triple Flag holds stream, royalty or other similar interests. Triple Flag generally has limited or no ability to independently verify such information. Although Triple Flag does not believe that such information is inaccurate or incomplete in any material respect, there can be no assurance that such third-party information is complete or accurate.

1 Gold Equivalent Ounces (“GEOs”)

GEOs are a non-IFRS measure that are based on stream and related interests as well as royalty interests and are calculated on a quarterly basis by dividing all revenue from such interests for the quarter by the average gold price during such quarter. The gold price is determined based on the LBMA PM fix. For periods longer than one quarter, GEOs are summed for each quarter in the period. Management uses this measure internally to evaluate our underlying operating performance across our stream and royalty portfolio for the reporting periods presented and to assist with the planning and forecasting of future operating results. GEOs are intended to provide additional information only and do not have any standardized definition under IFRS Accounting Standards and should not be considered in isolation or as a substitute for measures of performance prepared in accordance with IFRS Accounting Standards. The measures are not necessarily indicative of gross profit or operating cash flow as determined under IFRS Accounting Standards. Other companies may calculate these measures differently. The following table reconciles GEOs to revenue, the most directly comparable IFRS Accounting Standards measure:

($ millions, except average gold price and GEOs information)

Q1 2025

Q1 2024

Revenue

82.2

57.5

Average gold price per ounce

2,860

2,070

GEOs

28,761

27,794

2 Results are unaudited. The Company cautions that, whether or not expressly stated, all first quarter figures contained in this press release including, without limitation, sales and associated costs are preliminary, and reflect our expected first quarter results as of the date of this press release. Actual reported first quarter sales and associated costs are subject to management’s final review and may vary significantly from those expectations because of a number of factors, including, without limitation, additional or revised information, and changes in accounting standards or policies, or in how those standards are applied.

Investor Relations:

David Lee

Vice President, Investor Relations

Tel: +1 (416) 304-9770

Email: [email protected]

Media:

Gordon Poole, Camarco

Tel: +44 (0) 7730 567 938

Email: [email protected]

KEYWORDS: North America Canada

INDUSTRY KEYWORDS: Mining/Minerals Natural Resources

MEDIA:

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YieldMax™ ETFs Announces Distributions on SMCY (102.27%), MSTY (101.29%), ULTY (78.88%), AIYY (70.96%), LFGY (69.83%), and Others

CHICAGO and MILWAUKEE and NEW YORK, April 09, 2025 (GLOBE NEWSWIRE) — YieldMax™ today announced distributions for the YieldMax™ Weekly Payers and Group D ETFs listed in the table below.

ETF
Ticker



1

ETF Name Distribution
Frequency
Distribution
per Share
Distribution
Rate



2,




4

30-Day

SEC Yield


3

ROC


5

Ex-Date &
Record Date
Payment
Date
CHPY

*
YieldMax™ Semiconductor Portfolio Option Income ETF
Weekly
GPTY YieldMax™ AI & Tech Portfolio Option Income ETF
Weekly
$0.2360 35.40% 0.00% 0.00% 4/10/25 4/11/25
LFGY YieldMax™ Crypto Industry & Tech Portfolio Option Income ETF
Weekly
$0.4170 69.83% 0.00% 0.00% 4/10/25 4/11/25
QDTY YieldMax™ Nasdaq 100 0DTE Covered Call ETF
Weekly
$0.2199 29.87% 0.00% 100.00% 4/10/25 4/11/25
RDTY YieldMax™ R2000 0DTE Covered Call ETF
Weekly
$0.3590 45.69% 0.00% 100.00% 4/10/25 4/11/25
SDTY YieldMax™ S&P 500 0DTE Covered Call ETF
Weekly
$0.2270 29.60% 0.00% 100.00% 4/10/25 4/11/25
ULTY YieldMax™ Ultra Option Income Strategy ETF
Weekly
$0.0822 78.88% 2.21% 0.00% 4/10/25 4/11/25
YMAG YieldMax™ Magnificent 7 Fund of Option Income ETFs
Weekly
$0.0973 38.00% 69.89% 53.05% 4/10/25 4/11/25
YMAX YieldMax™ Universe Fund of Option Income ETFs
Weekly
$0.1289 57.35% 96.57% 64.98% 4/10/25 4/11/25
AIYY YieldMax™ AI Option Income Strategy ETF Every 4 weeks $0.2301 70.96% 4.89% 93.15% 4/10/25 4/11/25
AMZY YieldMax™ AMZN Option Income Strategy ETF Every 4 weeks $0.4877 43.54% 4.40% 89.31% 4/10/25 4/11/25
APLY YieldMax™ AAPL Option Income Strategy ETF Every 4 weeks $0.3023 33.00% 3.44% 44.35% 4/10/25 4/11/25
DISO YieldMax™ DIS Option Income Strategy ETF Every 4 weeks $0.3254 35.32% 4.03% 0.00% 4/10/25 4/11/25
MSTY YieldMax™ MSTR Option Income Strategy ETF Every 4 weeks $1.3356 101.29% 0.50% 0.48% 4/10/25 4/11/25
SMCY YieldMax™ SMCI Option Income Strategy ETF Every 4 weeks $1.5012 102.27% 3.01% 67.02% 4/10/25 4/11/25
WNTR

**
YieldMax™ Short MSTR Option Income Strategy ETF Every 4 weeks
XYZY YieldMax™ XYZ Option Income Strategy ETF Every 4 weeks $0.4412 59.61% 6.32% 89.82% 4/10/25 4/11/25
YQQQ YieldMax™ Short N100 Option Income Strategy ETF Every 4 weeks $0.4437 30.86% 3.08% 0.00% 4/10/25 4/11/25
Weekly Payers & Group A ETFs scheduled for next week: CHPY GPTY LFGY QDTY RDTY SDTY UTLY YMAG YMAX CRSH FEAT FIVY GOOY OARK SNOY TSLY TSMY XOMO YBIT



Performance data quoted represents past performance and is no guarantee of future results. Investment return and principal value of an investment will fluctuate so that an investor’s shares, when sold or redeemed, may be worth more or less than their original cost and current performance may be lower or higher than the performance quoted above. Performance current to the most recent month-end can be obtained by calling 

(833) 378-0717
.

Note: DIPS, FIAT,CRSH, YQQQ and WNTR are hereinafter referred to as the “Short ETFs.”

Distributions are not guaranteed. The Distribution Rate and 30-Day SEC Yield are not indicative of future distributions, if any, on the ETFs. In particular, future distributions on any ETF may differ significantly from its Distribution Rate or 30-Day SEC Yield. You are not guaranteed a distribution under the ETFs. Distributions for the ETFs (if any) are variable and may vary significantly from period to period and may be zero. Accordingly, the Distribution Rate and 30-Day SEC Yield will change over time, and such change may be significant.

Investors in the Funds will not have rights to receive dividends or other distributions with respect to the underlying reference asset(s).



*



The inception


date


for CHPY is April


2


, 202


5


.



**



The inception date for WNTR is March 26, 2025.


1
All YieldMax™ ETFs shown in the table above (except

YMAX

,

YMAG

,

FEAT

,

FIVY

and

ULTY

) have a gross expense ratio of 0.99%.

YMAX

,

YMAG

and

FEAT

have a Management Fee of 0.29% and Acquired Fund Fees and Expenses of 0.99% for a gross expense ratio of 1.28%.

FIVY

has a Management Fee of 0.29% and Acquired Fund Fees and Expenses of 0.59% for a gross expense ratio of 0.88%. “Acquired Fund Fees and Expenses” are indirect fees and expenses that the Fund incurs from investing in the shares of other investment companies, namely other YieldMax™ ETFs.

ULTY 

has a gross expense ratio after the fee waiver of 1.30%. The Advisor has agreed to a fee waiver of 0.10% through at least February 28, 2026

.

2
The Distribution Rate shown is as of clo
se
on

April


8


,


2025

.
The
Distribution Rate
is the annual
distribution rate
an investor would receive if the most recent distribution,

which includes option income

, remained the same going forward. The
Distribution Rate
is calculated by
annualizing
an ETF’s Distribution per Share and dividing
such annualized
amount by the ETF’s most recent NAV. The
Distribution Rate
represents a single distribution from the ETF and does not represent its total return.
Distributions may also include a combination of ordinary dividends, capital gain, and return of investor capital, which may decrease an ETF’s NAV and trading price over time. As a result, an investor may suffer significant losses to their
investment. These Distribution Rates may be caused by unusually favorable market conditions and may not be
sustainable. Such conditions may not continue to exist and there should be no expectation that this performance may be repeated in the future.

3
The 30-Day SEC Yield represents net investment income,

which excludes option income

,
earned by such ETF over the 30-Day period ended

March 31, 2025

, e
xpressed as an annual percentage rate based on such ETF’s share price at the end of the 30-Day period.

4
Each ETF’s strategy (

except those of the Short ETFs

) will cap potential gains if its reference asset’s shares increase in value, yet subjects an investor to all potential losses if the reference asset’s shares decrease in value. Such potential losses may not be offset by income received by the ETF.
Each

Short ETF’s

strategy will cap potential gains if its reference asset decreases in value, yet subjects an investor to all potential losses if the reference asset increases in value. Such potential losses may not be offset by income received by the ETF.

5
ROC refers to Return
of
Capital. The ROC percentage is the portion of the distribution that represents an investor’s original investment.



Each Fund has a limited operating history and while each Fund’s objective is to provide current income, there is no guarantee the Fund will make a distribution. Distributions are likely to vary greatly in amount.


Standardized Performance

For YMAX, click here. For YMAG, click here. For TSLY, click here. For OARK, click here. For APLY, click here. For NVDY, click here. For AMZY, click here. For FBY, click here. For GOOY, click here. For NFLY, click here. For CONY, click here. For MSFO, click here. For DISO, click here. For XOMO, click here. For JPMO, click here. For AMDY, click here. For PYPY, click here. For XYZY, click here. For MRNY, click here. For AIYY, click here. For MSTY, click here. For ULTY, click here. For YBIT, click here. For CRSH, click here. For GDXY, click here. For SNOY, click here. For ABNY, click here. For FIAT, click here. For DIPS, click here. For BABO, click here. For YQQQ, click here. For TSMY, click here. For SMCY, click here. For PLTY, click here. For BIGY, click here. For SOXY, click here. For MARO, click here. For FEAT, click here. For FIVY, click here. For LFGY, click here. For GPTY, click here. For CVNY, click here. For SDTY, click here. For QDTY, click here. For WNTR, click here. For CHPY, click here


Important Information

This material must be preceded or accompanied by the prospectus. For all prospectuses, click here.

Tidal Financial Group is the adviser for all YieldMax™ ETFs.

THE FUND, TRUST, AND ADVISER ARE NOT AFFILIATED WITH ANY UNDERLYING REFERENCE ASSET.


Risk Disclosures (applicable to all YieldMax ETFs referenced above,



except



the Short ETFs)

YMAX, YMAG, FEAT and FIVY generally invest in other YieldMax™ ETFs. As such, these two Funds are subject to the risks listed in this section, which apply to all the YieldMax™ ETFs they may hold from time to time.

Investing involves risk. Principal loss is possible.

Referenced Index Risk. The Fund invests in options contracts that are based on the value of the Index (or the Index ETFs). This subjects the Fund to certain of the same risks as if it owned shares of companies that comprised the Index or an ETF that tracks the Index, even though it does not.

Indirect Investment Risk. The Index is not affiliated with the Trust, the Fund, the Adviser, or their respective affiliates and is not involved with this offering in any way. Investors in the Fund will not have the right to receive dividends or other distributions or any other rights with respect to the companies that comprise the Index but will be subject to declines in the performance of the Index.

Russell 2000 Index Risks. The Index, which consists of small-cap U.S. companies, is particularly susceptible to economic changes, as these firms often have less financial resilience than larger companies. Market volatility can disproportionately affect these smaller businesses, leading to significant price swings. Additionally, these companies are often more exposed to specific industry risks and have less diverse revenue streams. They can also be more vulnerable to changes in domestic regulatory or policy environments.

Call Writing Strategy Risk. The path dependency (i.e., the continued use) of the Fund’s call writing strategy will impact the extent that the Fund participates in the positive price returns of the underlying reference asset and, in turn, the Fund’s returns, both during the term of the sold call options and over longer periods.

Counterparty Risk. The Fund is subject to counterparty risk by virtue of its investments in options contracts. Transactions in some types of derivatives, including options, are required to be centrally cleared (“cleared derivatives”). In a transaction involving cleared derivatives, the Fund’s counterparty is a clearing house rather than a bank or broker. Since the Fund is not a member of clearing houses and only members of a clearing house (“clearing members”) can participate directly in the clearing house, the Fund will hold cleared derivatives through accounts at clearing members.

Derivatives Risk. Derivatives are financial instruments that derive value from the underlying reference asset or assets, such as stocks, bonds, or funds (including ETFs), interest rates or indexes. The Fund’s investments in derivatives may pose risks in addition to, and greater than, those associated with directly investing in securities or other ordinary investments, including risk related to the market, imperfect correlation with underlying investments or the Fund’s other portfolio holdings, higher price volatility, lack of availability, counterparty risk, liquidity, valuation and legal restrictions.

Options Contracts. The use of options contracts involves investment strategies and risks different from those associated with ordinary portfolio securities transactions. The prices of options are volatile and are influenced by, among other things, actual and anticipated changes in the value of the underlying instrument, including the anticipated volatility, which are affected by fiscal and monetary policies and by national and international political, changes in the actual or implied volatility or the reference asset, the time remaining until the expiration of the option contract and economic events.

Distribution Risk. As part of the Fund’s investment objective, the Fund seeks to provide current income. There is no assurance that the Fund will make a distribution in any given period. If the Fund does make distributions, the amounts of such distributions will likely vary greatly from one distribution to the next.

High Portfolio Turnover Risk. The Fund may actively and frequently trade all or a significant portion of the Fund’s holdings. A high portfolio turnover rate increases transaction costs, which may increase the Fund’s expenses.

Liquidity Risk. Some securities held by the Fund, including options contracts, may be difficult to sell or be illiquid, particularly during times of market turmoil.

Non-Diversification Risk. Because the Fund is “non-diversified,” it may invest a greater percentage of its assets in the securities of a single issuer or a smaller number of issuers than if it was a diversified fund.

New Fund Risk. The Fund is a recently organized management investment company with no operating history. As a result, prospective investors do not have a track record or history on which to base their investment decisions.

Price Participation Risk. The Fund employs an investment strategy that includes the sale of call option contracts, which limits the degree to which the Fund will participate in increases in value experienced by the underlying reference asset over the Call Period.

Single Issuer Risk. Issuer-specific attributes may cause an investment in the Fund to be more volatile than a traditional pooled investment which diversifies risk or the market generally. The value of the Fund, which focuses on an individual security (ARKK, TSLA, AAPL, NVDA, AMZN, META, GOOGL, NFLX, COIN, MSFT, DIS, XOM, JPM, AMD, PYPL, SQ, MRNA, AI, MSTR, Bitcoin ETP, GDX®, SNOW, ABNB, BABA, TSM, SMCI, PLTR, MARA, CVNA), may be more volatile than a traditional pooled investment or the market as a whole and may perform differently from the value of a traditional pooled investment or the market as a whole.

Inflation Risk. Inflation risk is the risk that the value of assets or income from investments will be less in the future as inflation decreases the value of money. As inflation increases, the present value of the Fund’s assets and distributions, if any, may decline.

Indirect Investment Risk. The Index is not affiliated with the Trust, the Fund, the Adviser, or their respective affiliates and is not involved with this offering in any way.


Risk Disclosures (applicable



only



to GPTY)

Artificial Intelligence Risk. Issuers engaged in artificial intelligence typically have high research and capital expenditures and, as a result, their profitability can vary widely, if they are profitable at all. The space in which they are engaged is highly competitive and issuers’ products and services may become obsolete very quickly. These companies are heavily dependent on intellectual property rights and may be adversely affected by loss or impairment of those rights. The issuers are also subject to legal, regulatory, and political changes that may have a large impact on their profitability. A failure in an issuer’s product or even questions about the safety of the product could be devastating to the issuer, especially if it is the marquee product of the issuer. It can be difficult to accurately capture what qualifies as an artificial intelligence company.

Technology Sector Risk. The Fund will invest substantially in companies in the information technology sector, and therefore the performance of the Fund could be negatively impacted by events affecting this sector. Market or economic factors impacting technology companies and companies that rely heavily on technological advances could have a significant effect on the value of the Fund’s investments. The value of stocks of information technology companies and companies that rely heavily on technology is particularly vulnerable to rapid changes in technology product cycles, rapid product obsolescence, government regulation and competition, both domestically and internationally, including competition from foreign competitors with lower production costs. Stocks of information technology companies and companies that rely heavily on technology, especially those of smaller, less-seasoned companies, tend to be more volatile than the overall market. Information technology companies are heavily dependent on patent and intellectual property rights, the loss or impairment of which may adversely affect profitability.


Risk Disclosure (applicable



only



to MARO)

Digital Assets Risk: The Fund does not invest directly in Bitcoin or any other digital assets. The Fund does not invest directly in derivatives that track the performance of Bitcoin or any other digital assets. The Fund does not invest in or seek direct exposure to the current “spot” or cash price of Bitcoin. Investors seeking direct exposure to the price of Bitcoin should consider an investment other than the Fund. Digital assets like Bitcoin, designed as mediums of exchange, are still an emerging asset class. They operate independently of any central authority or government backing and are subject to regulatory changes and extreme price volatility.


Risk Disclosures (applicable



only



to BABO and TSMY)

Currency Risk: Indirect exposure to foreign currencies subjects the Fund to the risk that currencies will decline in value relative to the U.S. dollar. Currency rates in foreign countries may fluctuate significantly over short periods of time for a number of reasons, including changes in interest rates and the imposition of currency controls or other political developments in the U.S. or abroad.

Depositary Receipts Risk: The securities underlying BABO and TSMY are American Depositary Receipts (“ADRs”). Investment in ADRs may be less liquid than the underlying shares in their primary trading market.

Foreign Market and Trading Risk: The trading markets for many foreign securities are not as active as U.S. markets and may have less governmental regulation and oversight.

Foreign Securities Risk: Investments in securities of non-U.S. issuers involve certain risks that may not be present with investments in securities of U.S. issuers, such as risk of loss due to foreign currency fluctuations or to political or economic instability, as well as varying regulatory requirements applicable to investments in non-U.S. issuers. There may be less information publicly available about a non-U.S. issuer than a U.S. issuer. Non-U.S. issuers may also be subject to different regulatory, accounting, auditing, financial reporting, and investor protection standards than U.S. issuers.


Risk Disclosures (applicable



only



to GDXY)

Risk of Investing in Foreign Securities. The Fund is exposed indirectly to the securities of foreign issuers selected by GDX®’s investment adviser, which subjects the Fund to the risks associated with such companies. Investments in the securities of foreign issuers involve risks beyond those associated with investments in U.S. securities.

Risk of Investing in Gold and Silver Mining Companies. The Fund is exposed indirectly to gold and silver mining companies selected by GDX®’s investment adviser, which subjects the Fund to the risks associated with such companies.

The Fund invests in options contracts based on the value of the VanEck Gold Miners ETF (GDX®), which subjects the Fund to some of the same risks as if it owned GDX®, as well as the risks associated with Canadian, Australian and Emerging Market Issuers, and Small-and Medium-Capitalization companies.


Risk Disclosures (applicable



only



to YBIT)

YBIT does not invest directly in Bitcoin or any other digital assets. YBIT does not invest directly in derivatives that track the performance of Bitcoin or any other digital assets. YBIT does not invest in or seek direct exposure to the current “spot” or cash price of Bitcoin. Investors seeking direct exposure to the price of Bitcoin should consider an investment other than YBIT.

Bitcoin Investment Risk: The Fund’s indirect investment in Bitcoin, through holdings in one or more Underlying ETPs, exposes it to the unique risks of this emerging innovation. Bitcoin’s price is highly volatile, and its market is influenced by the changing Bitcoin network, fluctuating acceptance levels, and unpredictable usage trends.

Digital Assets Risk: Digital assets like Bitcoin, designed as mediums of exchange, are still an emerging asset class. They operate independently of any central authority or government backing and are subject to regulatory changes and extreme price volatility. Potentially No 1940 Act Protections. As of the date of this Prospectus, there is only a single eligible Underlying ETP, and it is an investment company subject to the 1940 Act.

Bitcoin
ETP Risk: The Fund invests in options contracts that are based on the value of the Bitcoin ETP. This subjects the Fund to certain of the same risks as if it owned shares of the Bitcoin ETP, even though it does not. Bitcoin ETPs are subject, but not limited, to significant risk and heightened volatility. An investor in a Bitcoin ETP may lose their entire investment. Bitcoin ETPs are not suitable for all investors. In addition, not all Bitcoin ETPs are registered under the Investment Company Act of 1940. Those Bitcoin ETPs that are not registered under such statute are therefore not subject to the same regulations as exchange traded products that are so registered.


Risk Disclosures (applicable



only



to the Short ETFs)

Investing involves risk. Principal loss is possible.

Price Appreciation Risk. As part of the Fund’s synthetic covered put strategy, the Fund purchases and sells call and put option contracts that are based on the value of the underlying reference asset. This strategy subjects the Fund to certain of the same risks as if it shorted the underlying reference asset, even though it does not. By virtue of the Fund’s indirect inverse exposure to changes in the value of the underlying reference asset, the Fund is subject to the risk that the value of the underlying reference asset increases. If the value of the underlying reference asset increases, the Fund will likely lose value and, as a result, the Fund may suffer significant losses.

Put Writing Strategy Risk. The path dependency (i.e., the continued use) of the Fund’s put writing (selling) strategy will impact the extent that the Fund participates in decreases in the value of the underlying reference asset and, in turn, the Fund’s returns, both during the term of the sold put options and over longer periods.

Purchased OTM Call Options Risk. The Fund’s strategy is subject to potential losses if the underlying reference asset increases in value, which may not be offset by the purchase of out-of-the-money (OTM) call options. The Fund purchases OTM calls to seek to manage (cap) the Fund’s potential losses from the Fund’s short exposure to the underlying reference asset if it appreciates significantly in value. However, the OTM call options will cap the Fund’s losses only to the extent that the value of the underlying reference asset increases to a level that is at or above the strike level of the purchased OTM call options. Any increase in the value of the underlying reference asset to a level that is below the strike level of the purchased OTM call options will result in a corresponding loss for the Fund. For example, if the OTM call options have a strike level that is approximately 100% above the then-current value of the underlying reference asset at the time of the call option purchase, and the value of the underlying reference asset increases by at least 100% during the term of the purchased OTM call options, the Fund will lose all its value. Since the Fund bears the costs of purchasing the OTM calls, such costs will decrease the Fund’s value and/or any income otherwise generated by the Fund’s investment strategy.

Counterparty Risk. The Fund is subject to counterparty risk by virtue of its investments in options contracts. Transactions in some types of derivatives, including options, are required to be centrally cleared (“cleared derivatives”). In a transaction involving cleared derivatives, the Fund’s counterparty is a clearing house rather than a bank or broker. Since the Fund is not a member of clearing houses and only members of a clearing house (“clearing members”) can participate directly in the clearing house, the Fund will hold cleared derivatives through accounts at clearing members.

Derivatives Risk. Derivatives are financial instruments that derive value from the underlying reference asset or assets, such as stocks, bonds, or funds (including ETFs), interest rates or indexes. The Fund’s investments in derivatives may pose risks in addition to, and greater than, those associated with directly investing in securities or other ordinary investments, including risk related to the market, imperfect correlation with underlying investments or the Fund’s other portfolio holdings, higher price volatility, lack of availability, counterparty risk, liquidity, valuation and legal restrictions.

Options Contracts. The use of options contracts involves investment strategies and risks different from those associated with ordinary portfolio securities transactions. The prices of options are volatile and are influenced by, among other things, actual and anticipated changes in the value of the underlying reference asset, including the anticipated volatility, which are affected by fiscal and monetary policies and by national and international political, changes in the actual or implied volatility or the reference asset, the time remaining until the expiration of the option contract and economic events.

Distribution Risk. As part of the Fund’s investment objective, the Fund seeks to provide current income. There is no assurance that the Fund will make a distribution in any given period. If the Fund does make distributions, the amounts of such distributions will likely vary greatly from one distribution to the next.

High Portfolio Turnover Risk. The Fund may actively and frequently trade all or a significant portion of the Fund’s holdings.

Liquidity Risk. Some securities held by the Fund, including options contracts, may be difficult to sell or be illiquid, particularly during times of market turmoil.

Non-Diversification Risk. Because the Fund is “non-diversified,” it may invest a greater percentage of its assets in the securities of a single issuer or a smaller number of issuers than if it was a diversified fund.

New Fund Risk. The Fund is a recently organized management investment company with no operating history. As a result, prospective investors do not have a track record or history on which to base their investment decisions.

Price Participation Risk. The Fund employs an investment strategy that includes the sale of put option contracts, which limits the degree to which the Fund will participate in decreases in value experienced by the underlying reference asset over the Put Period.

Single Issuer Risk. Issuer-specific attributes may cause an investment in the Fund to be more volatile than a traditional pooled investment which diversifies risk or the market generally. The value of the Fund, for any Fund that focuses on an individual security (e.g., TSLA, COIN, NVDA, MSTR), may be more volatile than a traditional pooled investment or the market as a whole and may perform differently from the value of a traditional pooled investment or the market as a whole.

Inflation Risk. Inflation risk is the risk that the value of assets or income from investments will be less in the future as inflation decreases the value of money. As inflation increases, the present value of the Fund’s assets and distributions, if any, may decline.


Risk Disclosures (applicable



only



to CHPY)

Semiconductor Industry Risk. Semiconductor companies may face intense competition, both domestically and internationally, and such competition may have an adverse effect on their profit margins. Semiconductor companies may have limited product lines, markets, financial resources or personnel. Semiconductor companies’ supply chain and operations are dependent on the availability of materials that meet exacting standards and the use of third parties to provide components and services.

The products of semiconductor companies may face obsolescence due to rapid technological developments and frequent new product introduction, unpredictable changes in growth rates and competition for the services of qualified personnel. Capital equipment expenditures could be substantial, and equipment generally suffers from rapid obsolescence. Companies in the semiconductor industry are heavily dependent on patent and intellectual property rights. The loss or impairment of these rights would adversely affect the profitability of these companies.


Risk Disclosures (applicable



only



to YQQQ)

Index Overview. The Nasdaq 100 Index is a benchmark index that includes 100 of the largest non-financial companies listed on the Nasdaq Stock Market, based on market capitalization.

Index Level Appreciation Risk. As part of the Fund’s synthetic covered put strategy, the Fund purchases and sells call and put option contracts that are based on the Index level. This strategy subjects the Fund to certain of the same risks as if it shorted the Index, even though it does not. By virtue of the Fund’s indirect inverse exposure to changes in the Index level, the Fund is subject to the risk that the Index level increases. If the Index level increases, the Fund will likely lose value and, as a result, the Fund may suffer significant losses. The Fund may also be subject to the following risks: innovation and technological advancement; strong market presence of Index constituent companies; adaptability to global market trends; and resilience and recovery potential.

Index Level Participation Risk. The Fund employs an investment strategy that includes the sale of put option contracts, which limits the degree to which the Fund will benefit from decreases in the Index level experienced over the Put Period. This means that if the Index level experiences a decrease in value below the strike level of the sold put options during a Put Period, the Fund will likely not experience that increase to the same extent and any Fund gains may significantly differ from the level of the Index losses over the Put Period. Additionally, because the Fund is limited in the degree to which it will participate in decreases in value experienced by the Index level over each Put Period, but has significant negative exposure to any increases in value experienced by the Index level over the Put Period, the NAV of the Fund may decrease over any given period. The Fund’s NAV is dependent on the value of each options portfolio, which is based principally upon the inverse of the performance of the Index level. The Fund’s ability to benefit from the Index level decreases will depend on prevailing market conditions, especially market volatility, at the time the Fund enters into the sold put option contracts and will vary from Put Period to Put Period. The value of the options contracts is affected by changes in the value and dividend rates of component companies that comprise the Index, changes in interest rates, changes in the actual or perceived volatility of the Index and the remaining time to the options’ expiration, as well as trading conditions in the options market. As the Index level changes and time moves towards the expiration of each Put Period, the value of the options contracts, and therefore the Fund’s NAV, will change. However, it is not expected for the Fund’s NAV to directly inversely correlate on a day-to-day basis with the returns of the Index level. The amount of time remaining until the options contract’s expiration date affects the impact that the value of the options contracts has on the Fund’s NAV, which may not be in full effect until the expiration date of the Fund’s options contracts. Therefore, while changes in the Index level will result in changes to the Fund’s NAV, the Fund generally anticipates that the rate of change in the Fund’s NAV will be different than the inverse of the changes experienced by the Index level.

YieldMax™ ETFs are distributed by Foreside Fund Services, LLC. Foreside is not affiliated with Tidal Financial Group, or YieldMax™ ETFs.

© 2025 YieldMax™ ETFs



Contact Gavin Filmore at [email protected] for more information.

AECOM announces planned dates for second quarter fiscal 2025 earnings results and conference call

AECOM announces planned dates for second quarter fiscal 2025 earnings results and conference call

DALLAS–(BUSINESS WIRE)–
AECOM (NYSE: ACM), the trusted global infrastructure leader, today announced that it intends to issue its second quarter fiscal 2025 earnings results after the U.S. market closes on May 5, 2025. The Company will also host a conference call and webcast with analysts and investors on May 6, 2025, at 8 a.m. Eastern Time / 7 a.m. Central Time, during which management will present the Company’s financial results and outlook, strategic accomplishments, and market and business trends.

The webcast and a replay will be available online at https://investors.aecom.com. The press release and presentation slides will be available on the Company’s website the day of the call and will contain additional financial information.

The conference call can be accessed directly by dialing 800-599-5188 (U.S.) or an international number at 646-307-1591 and entering passcode 7295287.

About AECOM

AECOM (NYSE: ACM) is the global infrastructure leader, committed to delivering a better world. As a trusted professional services firm powered by deep technical abilities, we solve our clients’ complex challenges in water, environment, energy, transportation and buildings. Our teams partner with public- and private-sector clients to create innovative, sustainable and resilient solutions throughout the project lifecycle – from advisory, planning, design and engineering to program and construction management. AECOM is a Fortune 500 firm that had revenue of $16.1 billion in fiscal year 2024. Learn more at aecom.com.

Media Contact:

Brendan Ranson-Walsh

Senior Vice President, Global Communications

1.213.996.2367

[email protected]

Investor Contact:

Will Gabrielski

Senior Vice President, Finance & Investor Relations

1.213.593.8208

[email protected]

KEYWORDS: United States North America Texas

INDUSTRY KEYWORDS: Utilities Construction & Property Sustainability Environment Energy Other Transport Other Construction & Property Transport

MEDIA:

Ryder Named Among “America’s Most Innovative Companies” in 2025 by Fortune

Ryder Named Among “America’s Most Innovative Companies” in 2025 by Fortune

  • Ryder recognized for advancements in product innovation, process innovation, and innovation culture
  • Ryder’s ongoing investments in next-generation logistics technologies drive industry transformation

MIAMI–(BUSINESS WIRE)–
As the transportation and logistics industry continues to evolve, Ryder System, Inc. (NYSE: R) remains at the forefront of innovation, developing leading-edge solutions that enhance efficiency and operational excellence. In recognition of these efforts, Ryder has been named to the Fortune list of “America’s Most Innovative Companies” in 2025.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250409383356/en/

Ryder has been named one of America’s Most Innovative Companies for 2025 by Fortune, recognized for its advancements in product and process innovation, as well as its strong culture of innovation. Through ongoing investments in next-generation logistics technologies, Ryder continues to drive transformation across the transportation and supply chain industries.

Ryder has been named one of America’s Most Innovative Companies for 2025 by Fortune, recognized for its advancements in product and process innovation, as well as its strong culture of innovation. Through ongoing investments in next-generation logistics technologies, Ryder continues to drive transformation across the transportation and supply chain industries.

“To fully optimize supply chains and transportation networks, we continue to build on the $1.7 billion in strategic investments we have made since 2018 to develop, acquire, and invest in innovative customer-centric technologies, products, and services,” says Karen Jones, Ryder’s chief marketing officer and head of new product development. “This recognition from Fortune is a testament to our team’s dedication to shape the future of logistics.”

As part of its innovation strategy, Ryder actively collaborates with start-ups and technology leaders to advance solutions that support e-commerce fulfillment, warehouse automation and robotics, digital logistics platforms, artificial intelligence, and advanced vehicle technologies. These initiatives are essential in addressing the evolving demands of modern supply chains and maintaining Ryder’s position at the forefront of industry transformation.

The Fortune “America’s Most Innovative Companies” list honors 300 U.S. companies that demonstrate outstanding innovation in product development, operational processes, and corporate culture. The evaluation process includes employee and expert surveys, as well as an in-depth analysis of each company’s intellectual property portfolio. Fortune and Statista surveyed more than 40,000 employees from eligible companies and more than 2,500 industry experts to rank companies across the three categories, in addition to evaluating a company’s patents within the product innovation category.

The ranking is built on three pillars:

  • Product innovation: Evaluation of a company’s products and services, covering aspects from attractiveness and design to usability and uniqueness
  • Process innovation: Analysis of all processes of a company, from sourcing and production to marketing, sales and support
  • Innovation culture: Extent to which a company fosters a spirit of entrepreneurship and creativity internally and allows employees to implement new ideas

“At Ryder, we recognize that innovation is not just about technology—it’s about finding smarter, more efficient ways to serve our customers and drive the industry forward. Over the past year, we have strengthened our supply chain solutions by expanding our capabilities in AI-driven analytics, process automation, and next-generation fleet technology. These advancements ensure our customers are well-equipped to meet the evolving challenges of modern logistics while optimizing their transportation networks for maximum efficiency,” adds Jones.

Among Ryder’s customer-centric innovations:

  • RyderShare™, a one-of-a-kind, end-to-end visibility and logistics technology platform that enables everyone involved in moving goods through supply chains to work together in real-time
  • RyderGyde™, the only application in the industry that allows drivers, fleet managers, and fleet owners to manage all aspects of fleets—anywhere, anytime, and on any device
  • In the area of next-generation vehicles, Ryder collaborates with manufacturers of electric vehicles and charging infrastructure, as well as companies working to commercialize autonomous vehicles and logistics networks
  • RyderVentures, a $50 million corporate venture capital fund, invests in and creates strategic alliances with start-ups exploring and addressing emerging technologies in the supply chain
  • Baton, a Ryder Technology Lab, is an innovation hub based in Silicon Valley that develops and scales cutting-edge technologies to streamline supply chain efficiencies.

The full Fortune “America’s Most Innovative Companies” 2025 list is available via America’s Most Innovative Companies 2025.

For more information about Ryder’s innovative solutions, visit www.ryder.com.

About Ryder System, Inc.

Ryder System, Inc. (NYSE: R) is a fully integrated port-to-door logistics and transportation company. It provides supply chain, dedicated transportation, and fleet management solutions, including warehousing and distribution, contract packaging and manufacturing, e-commerce fulfillment, last-mile delivery, managed transportation, professional drivers, freight brokerage, cross-border solutions, full-service fleet leasing, maintenance, commercial truck rental, and used vehicle sales to some of the world’s most-recognized brands. Ryder provides services to businesses across more than 20 industries throughout the United States, Mexico, and Canada. In addition, Ryder manages nearly 250,000 commercial vehicles, services fleets at approximately 760 maintenance locations, and operates nearly 300 warehouses encompassing more than 100 million square feet. Ryder is regularly recognized for its industry-leading practices; technology-driven innovations; environmental management; safety, health and security programs; and recruitment and hiring initiatives. www.ryder.com

Note Regarding Forward-Looking Statements: Certain statements and information included in this news release are “forward-looking statements” within the meaning of the Federal Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on our current plans and expectations and are subject to risks, uncertainties and assumptions. Accordingly, these forward-looking statements should be evaluated with consideration given to the many risks and uncertainties that could cause actual results and events to differ materially from those in the forward-looking statements including those risks set forth in our periodic filings with the Securities and Exchange Commission. New risks emerge from time to time. It is not possible for management to predict all such risk factors or to assess the impact of such risks on our business. Accordingly, we undertake no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.

ryder-ar

Jonathan Mayor, [email protected]

Amy Federman, [email protected]

KEYWORDS: United States North America Florida

INDUSTRY KEYWORDS: Other Transport Technology Trucking Rail Automotive Transport Software Data Management Logistics/Supply Chain Management Fleet Management

MEDIA:

Photo
Photo
Ryder has been named one of America’s Most Innovative Companies for 2025 by Fortune, recognized for its advancements in product and process innovation, as well as its strong culture of innovation. Through ongoing investments in next-generation logistics technologies, Ryder continues to drive transformation across the transportation and supply chain industries.
Logo
Logo

ANI Pharmaceuticals to Discuss First Quarter 2025 Financial Results on May 9, 2025, at 8:00 a.m. ET

PRINCETON, N.J., April 09, 2025 (GLOBE NEWSWIRE) — ANI Pharmaceuticals, Inc. (“ANI” or the “Company”) (NASDAQ: ANIP) today announced that the Company will release its first quarter 2025 financial results on Friday, May 9, 2025, prior to the market open.

Nikhil Lalwani, President and Chief Executive Officer, Stephen P. Carey, Senior Vice President, Finance, and Chief Financial Officer, and Chris Mutz, Head of Rare Disease, will host a conference call to discuss the results as follows:

Date Friday, May 9, 2025  
Time 8:00 a.m. ET  
Toll free (U.S.) 800-225-9448  
Conference ID 4921902  
Webcast (live and replay)  www.anipharmaceuticals.com, under the “Investors” section  

        

A replay of the conference call will be available within two hours of the call’s completion and will remain accessible for two weeks by dialing 800-753-8591 and entering access code 4921902.

About ANI Pharmaceuticals, Inc.

ANI Pharmaceuticals, Inc. (Nasdaq: ANIP) is a diversified biopharmaceutical company committed to its mission of “Serving Patients, Improving Lives” by developing, manufacturing, and commercializing innovative and high-quality therapeutics. The Company is focused on delivering sustainable growth through its Rare Disease business, which markets novel products in the areas of ophthalmology, rheumatology, nephrology, neurology, and pulmonology; its Generics business, which leverages R&D expertise, operational excellence, and U.S.-based manufacturing; and its Brands business. For more information, visit www.anipharmaceuticals.com.

Investor Relations Contact:

Lisa M. Wilson, In-Site Communications, Inc.
212-452-2793
[email protected]

SOURCE: ANI Pharmaceuticals, Inc.



Reliance, Inc. to Announce First Quarter 2025 Results on Wednesday, April 23rd

SCOTTSDALE, Ariz., April 09, 2025 (GLOBE NEWSWIRE) — Reliance, Inc. (NYSE:RS) announced today that it will report first quarter 2025 financial results for the period ended March 31, 2025, on Wednesday, April 23, 2025, after the market closes. Reliance management will host a conference call on Thursday, April 24, 2025, at 11:00 a.m. Eastern Time. The call will be broadcast live over the Internet hosted on the Investors section of the Company’s website at reliance.com.

Reliance, Inc. First Quarter 2025 Conference Call Details
   
DATE: Thursday, April 24, 2025
   
TIME: 8:00 a.m. Pacific Time
10:00 a.m. Central Time
11:00 a.m. Eastern Time
   
DIAL-IN: (877) 407-0792 (U.S. and Canada)
(201) 689-8263 (International)
   
CONFERENCE ID: 13752652
   
WEBCAST: https://viavid.webcasts.com/starthere.jsp?ei=1713274&tp_key=865b5093f8
      

For those unable to participate during the live broadcast, a replay of the call will also be available beginning that same day at 2:00 p.m. Eastern Time until 11:59 p.m. Eastern Time on May 8, 2025, by dialing (844) 512-2921 (U.S. and Canada) or (412) 317-6671 (International) and entering the conference ID: 13752652. The webcast will remain posted on the Investors section of Reliance’s website at reliance.com for 90 days.

About Reliance, Inc.

Founded in 1939, Reliance, Inc. (NYSE: RS) is a leading global diversified metal solutions provider and the largest metals service center company in North America. Through a network of 320 locations in 41 states and 10 countries outside of the United States, Reliance provides value-added metals processing services and distributes a full-line of over 100,000 metal products to more than 125,000 customers in a broad range of industries. Reliance focuses on small orders with quick turnaround and value-added processing services. In 2024, Reliance’s average order size was $2,980, approximately 50% of orders included value-added processing and approximately 40% of orders were delivered within 24 hours. Reliance, Inc.’s press releases and additional information are available on the Company’s website at reliance.com.

CONTACT:
(213) 576-2428
[email protected]

or Addo Investor Relations
(310) 829-5400



Endeavour Silver Produces 1,205,793 Oz Silver and 8,338 Oz Gold (1.9 Million Silver Equivalent Oz) in Q1 2025

VANCOUVER, British Columbia, April 09, 2025 (GLOBE NEWSWIRE) — Endeavour Silver Corp.
(“Endeavour” or the “Company”)
(NYSE: EXK; TSX: EDR) reports first quarter 2025 production of 1,205,793 silver ounces (oz) and 8,338 gold oz, for silver equivalent(1) (“AgEq”) production of 1.9 million oz.

“Our Q1 production results highlight the strength of our operations and our focus on consistent, efficient performance,” said Dan Dickson, Chief Executive Officer. “This steady momentum lays a solid foundation for the quarters ahead, as we sharpen our operational focus and prepare to bring Terronera into production.”


Q1 2025 Production Overview

  • Guanaceví in Line with Guidance: Production in line with plan, continues at full capacity with slightly lower silver and gold grades processed than plan.

  • Bolañitos Delivers Steady Production: Silver production was consistent with plan, while gold production was slightly below plan due to lower gold grades.

  • Metal Sales and Inventories: Sold 1,223,684 silver ounces and 8,538 gold ounces during the first quarter. A total of 219,151 silver ounces and 715 gold ounces of bullion inventory and 31,232 silver ounces and 452 gold ounces in concentrate inventory were held at quarter end.


Q1 2025 Mine Operations

Consolidated silver production was 1,205,793 ounces in Q1 2025, in line with plan and 17% lower than Q1 2024. Lower silver production was driven by 24% lower silver production at the Guanaceví mine, partially offset by 53% higher silver production at the Bolañitos mine compared to the same quarter in 2024. Consolidated gold production was 8,338 ounces in Q1 2025, 18% lower than Q1 2024 due to 28% lower gold production at the Bolañitos mine, and 3% lower gold production at the Guanaceví mine.

In Q1 2025, Guanaceví throughput was 11% lower than Q1 2024 and silver and gold grades were 13% lower and 4% higher, respectively, which drove the 24% lower silver and 3% lower gold output. Guanaceví throughput and grades were in line with plan. Supplies of local third-party feed continued to supplement mine production, amounting to 18% of quarterly throughput.

Bolañitos Q1 2025 throughput was in line with throughput in Q1 2024, combined with 60% higher silver grades offset by 26% lower gold grades. Silver production was 53% higher than the same period in 2024, while gold production was 28% lower. Throughput and silver grades were consistent with plan, while gold grades were slightly lower than plan. The grade variation is due to mining from different locations in the ore body.


Production Highlights for the Three Months Ended March 31, 2025

Three Months Ended March 31,


  2025 2024 % Change
Throughput (tonnes) 209,507 221,794 (6%)
Silver ounces produced 1,205,793 1,460,006 (17%)
Gold ounces produced 8,338 10,133 (18%)
Payable silver ounces produced 1,193,358 1,450,308 (18%)
Payable gold ounces produced 8,188 9,948 (18%)
Silver equivalent ounces produced1 1,872,833 2,270,677 (18%)
Silver ounces sold 1,223,684 1,756,094 (30%)
Gold ounces sold 8,538 10,880 (22%)


1

Silver equivalent (
AgEq
) is calculated using an 80:1
silver:gold
ratio.


Production Tables for the Three Months Ended March 31, 2025 by Mine

Production Tonnes Tonnes Grade Grade Recovery Recovery Silver Gold
by mine Processed per day Ag gpt Au gpt Ag % Au % Ounces Ounces
Guanaceví 102,438 1,138 348 1.30 88.6% 92.9% 1,015,327 3,989
Bolañitos 107,069 1,190 67 1.43 83.0% 88.3% 190,466 4,349
Consolidated 209,507 2,328 204 1.37 87.7% 90.4% 1,205,793 8,338

gpt = grams per tonne

Totals may not add up due to rounding


About Endeavour Silver

Endeavour is a mid-tier precious metals company with a strong commitment to sustainable and responsible mining practices. With operations in Mexico and the development of the new cornerstone mine in Jalisco State, the Company aims to contribute positively to the mining industry and the communities in which it operates. In addition, Endeavour has a portfolio of exploration projects in Mexico, Chile and the United States to facilitate its goal to become a premier senior silver producer.


Qualified Person

Dale Mah, P.Geo., Vice President Corporate Development, a qualified person under NI 43-101, has approved the scientific and technical information related to operations matters in this news release.


2025 Financial Results and Conference Call

Q1 2025 financial results will be released before market open on Tuesday May 13, 2025, and Management will host a conference call the same day at 10:00 a.m. PT / 1:00 p.m. ET to discuss the results.

Date:   Tuesday May 13, 2025
     
Time:   10:00am PT / 1:00pm ET
     
Telephone:   Canada & US + 1-833-752-3348
International + 1-647-846-2804
     
Replay:   Canada & US +1- 855-669-9658
International +1-412-317-0088
Access code is 2198664; audio replay will be available on Company’s website
     


Contact Information

Allison Pettit
Director, Investor Relations
Email: [email protected]
Website: www.edrsilver.com


Cautionary Note Regarding Forward-Looking Statements

This news release contains “forward-looking statements” within the meaning of the United States Private Securities Litigation Reform Act of 1995 and “forward-looking information” within the meaning of applicable Canadian securities legislation. Such forward-looking statements and information herein include but are not limited to statements regarding Endeavour’s preparation to bring Terronera into production and Endeavour’s anticipated performance for upcoming financial quarters. The Company does not intend to and does not assume any obligation to update such forward-looking statements or information, other than as required by applicable law.

Forward-looking statements or information involve known and unknown risks, uncertainties and other factors that may cause the actual results, level of activity, production levels, performance or achievements of Endeavour and its operations to be materially different from those expressed or implied by such statements. Such factors include but are not limited to changes in production and costs guidance; the ongoing effects of inflation and supply chain issues on mine economics; changes in national and local governments’ legislation, taxation, controls, regulations and political or economic developments in Canada, Chile, the USA, and Mexico; financial risks due to precious metals prices; operating or technical difficulties in mineral exploration, development and mining activities; risks and hazards of mineral exploration, development and mining; the speculative nature of mineral exploration and development; risks in obtaining necessary licenses and permits; fluctuations in the prices of silver and gold; fluctuations in currency markets (particularly the Mexican peso, Chilean peso, Canadian dollar and U.S. dollar); and challenges to the Company’s title to properties; as well as those factors described in the section “Risk Factors” contained in the Company’s most recent form 40F/Annual Information Form filed with the S.E.C. and Canadian securities regulatory authorities.

Forward-looking statements are based on assumptions management believes to be reasonable, including but not limited to: the continued operation of the Company’s mining operations, no material adverse change in the market price of commodities, forecast mine economics, mining operations will function and the mining products will be completed in accordance with management’s expectations and achieve their stated production outcomes, and such other assumptions and factors as set out herein. Although the Company has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking statements or information, there may be other factors that cause results to be materially different from those anticipated, described, estimated, assessed or intended. These forward-looking statements represent the Company’s views as of the date of this release. There can be no assurance that any forward-looking statements or information will be accurate as actual results and future events could differ materially from those anticipated in such statements or information. Accordingly, readers should not place undue reliance on forward-looking statements or information.