{"id":996827,"date":"2026-08-20T05:33:29","date_gmt":"2026-08-20T09:33:29","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/biontech-highlights-late-stage-lung-cancer-pipeline-momentum-and-first-global-data-for-pumitamig-elfetabart-drozuntecan-novel-novel-combination-at-wclc-2026\/"},"modified":"2026-08-20T05:33:29","modified_gmt":"2026-08-20T09:33:29","slug":"biontech-highlights-late-stage-lung-cancer-pipeline-momentum-and-first-global-data-for-pumitamig-elfetabart-drozuntecan-novel-novel-combination-at-wclc-2026","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/biontech-highlights-late-stage-lung-cancer-pipeline-momentum-and-first-global-data-for-pumitamig-elfetabart-drozuntecan-novel-novel-combination-at-wclc-2026\/","title":{"rendered":"BioNTech Highlights Late-Stage Lung Cancer Pipeline Momentum and First Global Data for Pumitamig\/Elfetabart Drozuntecan Novel-Novel Combination at WCLC 2026"},"content":{"rendered":"<div class=\"mw_release\">\n<ul>\n<li style=\"margin-top:0cm;margin-bottom:0cm;text-align:justify\">\n          <i>Pumitamig plus B7H3-targeting elfetabart drozuntecan delivers the first data in lung cancer for any PD-(L)1xVEGF bispecific immunomodulator combined with an antibody-drug conjugate, underscoring BioNTech\u2019s leadership in novel-novel combination treatment strategies<\/i>\n        <\/li>\n<li style=\"margin-top:0cm;margin-bottom:0cm;text-align:justify\">\n          <i>Updated <\/i><br \/>\n          <i>overall survival data for gotistobart from the PRESERVE-003 Phase 3 clinical trial will add to the growing body of evidence for this chemotherapy-free treatment approach in the second- and later-line treatment of advanced squamous non-small cell lung cancer following prior immunotherapy<\/i>\n        <\/li>\n<li style=\"margin-top:0cm;margin-bottom:0cm;text-align:justify\">\n          <i>BioNTech is advancing a diversified development program in lung cancer treatment spanning more than 16 ongoing clinical trials across subtypes, biomarkers and treatment settings, including five ongoing Phase 3 clinical trials and two novel-novel combination trials<\/i>\u00a0<\/li>\n<\/ul>\n<p align=\"justify\">\n        <b>MAINZ, Germany, August 20, 2026<\/b>\u00a0\u2013\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=9R3sY_e9iNSrJ4bqyPJktQ_moth3rrGeNk-Tyme7E8IMOsku8qpRBFJpga-rnDUWBCVJ9RyrSeKvb3n_CJ3kPsb7FUJpHa0alb6fkirsf7b3TzPp4mOfY7zQzLj4peQj\" rel=\"nofollow\" target=\"_blank\">BioNTech SE<\/a> (Nasdaq: BNTX, \u201cBioNTech\u201d or \u201cthe Company\u201d) will present new clinical data from its diversified development program in lung cancer treatment at the IASLC 2026 World Conference on Lung Cancer (\u201cWCLC\u201d) in Seoul, Republic of Korea, from September 12-15, 2026.<\/p>\n<p align=\"justify\">The breadth of data highlights the latest progress across key strategic assets, pumitamig (BNT327\/BMS986545) and gotistobart (BNT316\/ONC-392), as well as BioNTech\u2019s mRNA-based immunotherapy approaches, highlighting the strength of BioNTech\u2019s lung cancer treatment pipeline. Additionally, a late breaking oral presentation will detail data from the novel-novel combination trial of pumitamig with the investigational B7H3-targeted antibody-drug conjugate (\u201cADC\u201d) elfetabart drozuntecan (elfe-D or BNT324\/DB-1311), representing the first combination data for any PD-(L)1xVEGF bispecific immunomodulator and an ADC in lung cancer.<\/p>\n<p align=\"justify\">\u201cProgress in lung cancer care means both improving treatment outcomes for patients and, importantly, finding better options for more patients who still do not sufficiently benefit from current standard therapies,\u201d said <b>Prof. \u00d6zlem T\u00fcreci, M.D., Co-Founder and Chief Medical Officer at BioNTech<\/b>. \u201cThe data we are presenting at this year\u2019s WCLC provide further clinical evidence for our late-stage assets, gotistobart and pumitamig, and help to define the role of next-generation immunomodulators in addressing unmet medical needs in lung cancer. We are also presenting the first clinical evidence from a novel-novel treatment combination in lung cancer as part of our evaluation of pumitamig as a potential backbone for combination strategies of complementary mechanisms. Taken together, these data will inform the next steps in our clinical development programs and our broader efforts to expand treatment options for patients.\u201d<\/p>\n<p align=\"justify\">\n        <b>Highlights from BioNTech\u2019s presentations at WCLC 2026:<\/b>\n      <\/p>\n<p align=\"justify\">\n        <i>Novel-novel combination trial of pumitamig, developed in collaboration with Bristol Myers Squibb Company (\u201cBMS\u201d), and elfetabart drozuntecan, developed in collaboration with Duality Biologics (Suzhou) Co. Ltd. (\u201cDualityBio\u201d):<\/i>\n      <\/p>\n<ul>\n<li style=\"margin-top:0cm;margin-bottom:0cm;text-align:justify\">\n          <b>Advanced\/metastatic SCLC and NSCLC<\/b>: First data from the global Phase 1\/2 trial (<a href=\"http:\/\/clinicaltrials.gov\/study\/NCT06892548\" rel=\"nofollow\" target=\"_blank\">NCT06892548<\/a>) evaluating pumitamig in combination with the B7H3-targeting ADC elfetabart drozuntecan in patients with advanced or metastatic small cell lung cancer (\u201cSCLC\u201d) and NSCLC will be presented for this novel-novel treatment combination approach, underlining BioNTech\u2019s leadership in novel-novel combination treatment strategies.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <i>Gotistobart \u2013 a tumor microenvironment-selective regulatory T cell depletion candidate targeting CTLA-4, developed in collaboration with OncoC4, Inc. (\u201cOncoC4\u201d):<\/i>\n      <\/p>\n<ul>\n<li style=\"margin-top:0cm;margin-bottom:0cm;text-align:justify\">\n          <b>2L+ squamous NSCLC<\/b>: Updated overall survival data from stage 1 of the PRESERVE-003 Phase 3 clinical trial (<a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05671510\" rel=\"nofollow\" target=\"_blank\">NCT05671510<\/a>) of gotistobart in patients with squamous non-small cell lung cancer (\u201cNSCLC\u201d) who progressed on prior PD-(L)1 inhibitor treatment will be presented. The results further contribute to the growing body of evidence for this chemotherapy-free treatment approach. The pivotal stage 2 part of the trial is ongoing.<\/li>\n<\/ul>\n<p align=\"justify\">All abstracts are available through the <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=rUqHwtngrgEpph4GEHxdUVScijZuNg3vVbGrukJIlW1FQfy7uisSrCP1jKw9pojX2Cva-wdzJ4HUq6DAq5tUs-taHx2UdacUsL9MlP82F4KU7ViYPDn4Yz-mfdqolK07ZqJZ07QSiDClv_Y-HgQgvZXCCFVQLuxZ397WjIbOhpWDkZo0vfoK4e7-P6zXkePr\" rel=\"nofollow\" target=\"_blank\">WCLC website<\/a>. Further information on BioNTech\u2019s lung cancer pipeline can be accessed here.<\/p>\n<p align=\"justify\">\n        <b><br \/>\n          <u>Full presentation details:<\/u><br \/>\n        <\/b>\n      <\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"width:143.2px;text-align: left;vertical-align: middle;border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;vertical-align: top\">\n            <b>Candidate<\/b>\n          <\/td>\n<td style=\"width:239.07px;text-align: left;vertical-align: middle;border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">\n            <b>Abstract Title<\/b>\n          <\/td>\n<td style=\"width:248.67px;text-align: left;vertical-align: middle;border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">\n            <b>Abstract Number\/Presentation Details<\/b>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"width:143.2px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;vertical-align: top\">\n            <b>Pumitamig + elfetabart drozuntecan<\/b>\n          <\/td>\n<td style=\"width:239.07px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">Pumitamig (PD-L1 x VEGF-A bsAb) + Elfetabart Drozuntecan (Elfe-D, B7H3 ADC) in Patients with Advanced\/Metastatic Lung Cancer (NSCLC or SCLC)<\/td>\n<td style=\"width:248.67px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top;text-align: left;vertical-align: middle\">Abstract # OA14.01<br \/>Oral Presentation<br \/>The Breakthrough Immunotherapy for Advanced NSCLC<br \/>Sep 15, 2026: 12:30 &#8211; 01:45pm KST<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"3\" style=\"width:143.2px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;vertical-align: top\">\n            <b>Pumitamig<\/b>\n          <\/td>\n<td style=\"width:239.07px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">First-line Pumitamig (PD-L1 \u00d7 VEGF-A bsAb) Plus Chemotherapy in Unresectable Malignant Mesothelioma: Long-term PFS and OS<\/td>\n<td style=\"width:248.67px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top;text-align: left;vertical-align: middle\">Abstract #MO04.09<br \/>Mini Oral<br \/>Novel Therapeutics and Molecular Insights in Thymic Malignancies and Pleural Mesothelioma<br \/>Sep 13, 2026: 4:45 &#8211; 6:00pm KST<\/td>\n<\/tr>\n<tr>\n<td style=\"width:239.07px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">ROSETTA Lung\u2011201: A Phase 3 Trial of Pumitamig Monotherapy vs Durvalumab in Unresectable Stage III NSCLC Post-Chemoradiation<\/td>\n<td style=\"width:248.67px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top;text-align: left;vertical-align: middle\">Abstract #P2.330<br \/>Poster<br \/>Clinical Trials in Progress<br \/>Sep 14, 2026: 10:30am &#8211; 12:00pm KST<\/td>\n<\/tr>\n<tr>\n<td style=\"width:239.07px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">ROSETTA Lung-202: A Phase 3 trial of first-line pumitamig monotherapy vs pembrolizumab in locally advanced\/metastatic NSCLC<\/td>\n<td style=\"width:248.67px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top;text-align: left;vertical-align: middle\">Abstract #P2.355<br \/>Poster<br \/>Clinical Trials in Progress<br \/>Sep 14, 2026: 10:30am &#8211; 12:00pm KST<\/td>\n<\/tr>\n<tr>\n<td style=\"width:143.2px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;vertical-align: top\">\n            <b>Gotistobart<\/b>\n          <\/td>\n<td style=\"width:239.07px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">Gotistobart vs Docetaxel in Metastatic Squamous NSCLC After PD-(L)1 Progression: Updated Overall Survival of the stage 1 of PRESERVE-003<\/td>\n<td style=\"width:248.67px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top;text-align: left;vertical-align: middle\">Abstract #MO07.04<br \/>Mini Oral<br \/>Novel Immunotherapeutic Strategies in mNSCLC<br \/>Sep 14, 2026: 5:00 &#8211; 6:15pm KST<\/td>\n<\/tr>\n<tr>\n<td style=\"width:143.2px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;vertical-align: top\">\n            <b>BNT116<\/b>\n          <\/td>\n<td style=\"width:239.07px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">Neoadjuvant BNT116 + Cemiplimab + Carboplatin + Paclitaxel in Resectable NSCLC: Preliminary Results From a Phase I Trial<\/td>\n<td style=\"width:248.67px;text-align: left;vertical-align: middle;border-right: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top;text-align: left;vertical-align: middle\">Abstract #MO06.03<br \/>Mini Oral<br \/>Emerging Precision Approaches in Perioperative Therapy for Resectable NSCLC Integrating Targeted Therapy, Immunotherapy, Biomarkers, and Multimodal Strategies<br \/>Sep 14, 2026: 3:30 &#8211; 4:45pm KST<\/td>\n<\/tr>\n<\/table>\n<p>\n        <b><br \/>\n          <br \/>About BioNTech in Lung Cancer Treatment<\/b><br \/>\n        <br \/>Lung cancer is one of BioNTech\u2019s key focus areas. Through a diversified portfolio of investigational next-generation immunomodulators, ADCs and mRNA-based cancer immunotherapies, the Company is pursuing multiple approaches designed to address significant unmet needs for patients across lung cancer subtypes, histologies and treatment settings. BioNTech\u2019s clinical pipeline encompasses both monotherapies and combinations with standard of care treatments, as well as novel-novel combination regimens aimed at delivering differentiated therapeutic profiles for the treatment of patients with lung cancer. With 16 ongoing lung cancer trials, including five pivotal Phase 3 and two novel-novel combination trials, BioNTech is advancing a comprehensive development strategy with the aim of improving outcomes for patients across the continuum of lung cancer.<\/p>\n<p align=\"justify\">\n        <b>About BioNTech<\/b><br \/>\n        <br \/>BioNTech is a global next generation biopharmaceutical company pioneering novel investigative therapies for cancer and other serious diseases. In oncology, BioNTech is committed to transforming how cancer is treated. Its ambition is to develop innovative medicines with pan-tumor or synergistic potential to address cancer from multiple angles and across the full continuum of the disease from early- to late-stage. Its growing late-stage oncology pipeline comprises complementary treatment approaches spanning immunomodulators, antibody drug conjugates, and mRNA cancer immunotherapies. BioNTech has partnered with multiple global and specialized pharmaceutical collaborators leveraging complementary expertise and resources to accelerate innovation and drive progress, including Bristol Myers Squibb, Duality Biologics, Genentech, a member of the Roche Group, Genmab, MediLink, OncoC4, and Pfizer.<\/p>\n<p align=\"justify\">For more information, please visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=CN-lIPKgN6YhwtGaUiR-PdCXA6EWhmo0cTtkZVuf6CFgQx70gUZaNnAM-HBuX7hQj-FkWgaOh7wZwE3RKXQXjR4v0z-9Q61PveFFcrTG_Ur3GVhuBFqL1385Nx21FEPq\" rel=\"nofollow\" target=\"_blank\">www.BioNTech.com<\/a>.<\/p>\n<p align=\"justify\">\n        <b>BioNTech Forward-Looking Statements<\/b><br \/>\n        <br \/>This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, but not limited to, statements concerning: the initiation, timing, progress and results of BioNTech\u2019s research and development programs in oncology, including the targeted timing and number of additional potentially registrational trials; BioNTech\u2019s and its collaborators\u2019 current and future preclinical and clinical trials in oncology, including the investigational bispecific immunomodulator pumitamig (BNT327\/BMS986545) in unresectable malignant mesothelioma, the investigational anti-CTLA-4 antibody gotistobart (BNT316\/ONC-392) in metastatic squamous NSCLC, the investigational B7H3-targeted ADC elfetabart drozuntecan (BNT324\/DB-1311) in combination with pumitamig in (N)SCLC, and the investigational mRNA cancer immunotherapy candidate BNT116 in resectable NSCLC; the nature and characterization of and timing for release of clinical data across BioNTech\u2019s platforms, which is subject to peer review, regulatory review and market interpretation; the planned next steps in BioNTech\u2019s pipeline programs, including, but not limited to, statements regarding timing or plans for initiation or enrollment of clinical trials, or submission for and receipt of product approvals and potential commercialization with respect to BioNTech\u2019s product candidates; and the potential safety and efficacy of BioNTech\u2019s product candidates. In some cases, forward-looking statements can be identified by terminology such as \u201cwill,\u201d \u201cmay,\u201d \u201cshould,\u201d \u201cexpects,\u201d \u201cintends,\u201d \u201cplans,\u201d \u201caims,\u201d \u201canticipates,\u201d \u201cbelieves,\u201d \u201cestimates,\u201d \u201cpredicts,\u201d \u201cpotential,\u201d \u201ccontinue,\u201d or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words.<\/p>\n<p align=\"justify\">The forward-looking statements in this press release are based on BioNTech\u2019s current expectations and beliefs of future events and are neither promises nor guarantees. You should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond BioNTech\u2019s control, and which could cause actual results to differ materially and adversely from those expressed or implied by these forward-looking statements. These risks and uncertainties include, but are not limited to: the uncertainties inherent in research and development, including the ability to meet anticipated clinical endpoints, commencement and\/or completion dates for clinical trials, projected data release timelines, regulatory submission dates, regulatory approval dates and\/or launch dates, as well as risks associated with preclinical and clinical data, including the data discussed in this release, and including the possibility of unfavorable new preclinical, clinical or safety data and further analyses of existing preclinical, clinical or safety data; the nature of the clinical data, which is subject to ongoing peer review, regulatory review and market interpretation; the ability to produce comparable clinical results in future clinical trials; the timing of and BioNTech\u2019s ability to obtain and maintain regulatory approval for its product candidates; discussions with regulatory agencies regarding timing and requirements for additional clinical trials; the impact of tariffs and escalations in trade policy; BioNTech\u2019s ability to identify research opportunities and discover and develop investigational medicines; the ability and willingness of BioNTech\u2019s third-party collaborators to continue research and development activities relating to BioNTech&#8217;s development candidates and investigational medicines; unforeseen safety issues and potential claims that are alleged to arise from the use of products and product candidates developed or manufactured by BioNTech; BioNTech\u2019s and its collaborators\u2019 ability to commercialize and market its product candidates, if approved; BioNTech\u2019s ability to manage its development and related expenses; regulatory and political developments; BioNTech\u2019s ability to effectively scale its production capabilities and manufacture its products and product candidates; risks relating to the global financial system and markets; and other factors not known to BioNTech at this time. <\/p>\n<p align=\"justify\">You should review the risks and uncertainties described under the heading \u201cRisk Factors\u201d in BioNTech\u2019s Report on Form 6-K for the period ended June 30, 2026 and in subsequent filings made by BioNTech with the SEC, which are available on the SEC\u2019s website at\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=CN-lIPKgN6YhwtGaUiR-Pb9IVPyZ-PqAf9syWNB0Ev7EUherLoDL4daAQzD74QhPFAJoWshO6iG1AusspwqIwMdr96NpOaOIPpa-8Tb8HBls4QE37ZvGmhYwSmfMBQuOsBUbW_6VdXrUkEBciOrymKzU56xEl0tc_zynEKM5079BJM67Z5msYLV2A1_LwbrPMSoRzCyGYAdSCG7TLhU6H0jibv9UnEks30JMJ3tzsgTBKf2bUJvbUYvH8CaaTakXGU7vRSX6RVX04egEVi28b4TkXqJ6ugs8G1M5pwbSRBkrZ1F1WnbErUmlaCmwP0PvQjcWXPjmF5EKiMXEnHa7Ib-LK8Kv2F3Um7vniDVtJ9RuISKywXS0cUQGB8vN6vFEtu9nQWq3zZGN-hjNuq0nqK8Hquz78NCySJ1NEQgLaTlKBPd_gCEfQ0TsfQ761oo1o380irHzRtOCbHAAhLM-LQ==\" rel=\"nofollow\" target=\"_blank\">www.sec.gov<\/a>. These forward-looking statements speak only as of the date hereof. Except as required by law, BioNTech disclaims any intention or responsibility for updating or revising any forward-looking statements contained in this press release in the event of new information, future developments or otherwise.<\/p>\n<p align=\"justify\">\n        <b>CONTACTS<\/b>\n      <\/p>\n<p align=\"justify\">\n        <b>Media Relations<\/b><br \/>\n        <br \/>Jasmina Alatovic<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=ND1AzN7KfBF1d1vD0W0TGCE1gLNNLKyDkNX7w77t40XdAKh6QW5MiESrKavitelY-qJluI0YHgF87cIkjEClqMf8kR1ZvKofZGE_Gt4__hE=\" rel=\"nofollow\" target=\"_blank\">Media@biontech.de<\/a><\/p>\n<p align=\"justify\">\n        <b>Investor Relations<\/b><br \/>\n        <br \/>Douglas Maffei, PhD <br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=90uRwjsyyZbwrt0xFeHux0KmNX0vIhtxL0sJtUAs_6om6AHzhMl_2UCXFhKsg94J8P_rjTZ8RtWn8IedakQOW3-qOXJhWMa0Gtl4Bc26TeA=\" rel=\"nofollow\" target=\"_blank\">Investors@biontech.de<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=MTAwMTI1ODQ5NSM0MDI0OTAyNDUjMjAwMDk4NQ==\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml-eu.globenewswire.com\/media\/NDA5YjA1YjEtOTllNS00NDQyLTk0ZGYtMTdiMWI1NGUwN2YzLTEwMTI1NTgtMjAyNi0wOC0yMC1lbg==\/tiny\/BioNTech-SE.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Pumitamig plus B7H3-targeting elfetabart drozuntecan delivers the first data in lung cancer for any PD-(L)1xVEGF bispecific immunomodulator combined with an antibody-drug conjugate, underscoring BioNTech\u2019s leadership in novel-novel combination treatment strategies Updated overall survival data for gotistobart from the PRESERVE-003 Phase 3 clinical trial will add to the growing body of evidence for this chemotherapy-free treatment approach in the second- and later-line treatment of advanced squamous non-small cell lung cancer following prior immunotherapy BioNTech is advancing a diversified development program in lung cancer treatment spanning more than 16 ongoing clinical trials across subtypes, biomarkers and treatment settings, including five ongoing Phase 3 clinical trials and two novel-novel combination trials\u00a0 MAINZ, Germany, August 20, 2026\u00a0\u2013\u00a0BioNTech SE (Nasdaq: BNTX, \u201cBioNTech\u201d or \u201cthe Company\u201d) &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/biontech-highlights-late-stage-lung-cancer-pipeline-momentum-and-first-global-data-for-pumitamig-elfetabart-drozuntecan-novel-novel-combination-at-wclc-2026\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;BioNTech Highlights Late-Stage Lung Cancer Pipeline Momentum and First Global Data for Pumitamig\/Elfetabart Drozuntecan Novel-Novel Combination at WCLC 2026&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-996827","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>BioNTech Highlights Late-Stage Lung Cancer Pipeline Momentum and First Global Data for Pumitamig\/Elfetabart Drozuntecan Novel-Novel Combination at WCLC 2026 - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/biontech-highlights-late-stage-lung-cancer-pipeline-momentum-and-first-global-data-for-pumitamig-elfetabart-drozuntecan-novel-novel-combination-at-wclc-2026\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BioNTech Highlights Late-Stage Lung Cancer Pipeline Momentum and First Global Data for Pumitamig\/Elfetabart Drozuntecan Novel-Novel Combination at WCLC 2026 - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Pumitamig plus B7H3-targeting elfetabart drozuntecan delivers the first data in lung cancer for any PD-(L)1xVEGF bispecific immunomodulator combined with an antibody-drug conjugate, underscoring BioNTech\u2019s leadership in novel-novel combination treatment strategies Updated overall survival data for gotistobart from the PRESERVE-003 Phase 3 clinical trial will add to the growing body of evidence for this chemotherapy-free treatment approach in the second- and later-line treatment of advanced squamous non-small cell lung cancer following prior immunotherapy BioNTech is advancing a diversified development program in 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