{"id":994052,"date":"2026-08-12T09:27:38","date_gmt":"2026-08-12T13:27:38","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/bone-biologics-achieves-32-month-validated-shelf-life-for-rhnell-1\/"},"modified":"2026-08-12T09:27:38","modified_gmt":"2026-08-12T13:27:38","slug":"bone-biologics-achieves-32-month-validated-shelf-life-for-rhnell-1","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/bone-biologics-achieves-32-month-validated-shelf-life-for-rhnell-1\/","title":{"rendered":"Bone Biologics Achieves 32-Month Validated Shelf Life for rhNELL-1"},"content":{"rendered":"

\nMilestone strengthens manufacturing flexibility and supports pivotal study readiness
\n<\/h2>\n
\n

BURLINGTON, Mass, Aug. 12, 2026 (GLOBE NEWSWIRE) — Bone Biologics Corporation (“Bone Biologics” or the “Company”) (NASDAQ: BBLG, BBLGW), a developer of orthobiologic products for spine fusion markets, today announces that the validated shelf life of its rhNELL-1 protein has been extended to 32 months.<\/p>\n

\u201cReaching a 32-month validated shelf life gives us greater flexibility in how we manufacture, store and distribute rhNELL-1 as we prepare for pivotal-study scale,\u201d said Jeff Frelick, Chief Executive Officer. \u201cWe have achieved each stability milestone on the timeline communicated to shareholders. By extending the period the product can be held before use, we believe this milestone supports more efficient lot sizing, inventory management and distribution planning as our first-in-human NB1 study advances toward completion of enrollment.\u201d<\/p>\n

The extension is supported by third-party stability data and builds on the 29-month milestone announced in May 2026 and the 24-month milestone achieved in December 2025, continuing a progression from the Company’s earlier validated 12- and 18-month shelf-life milestones. A 32-month validated shelf life is expected to further enhance manufacturing efficiency, lot sizing, inventory management, distribution planning, and supply-chain flexibility as the Company advances rhNELL-1 through development.<\/p>\n

NB1, the Company\u2019s lead product candidate, combines rhNELL-1 protein with demineralized bone matrix to provide controlled bone regeneration. Bone Biologics is currently conducting a multicenter, prospective, randomized pilot clinical study evaluating NB1 in up to 30 subjects with degenerative disc disease undergoing transforaminal lumbar interbody fusion in Australia.<\/p>\n

\n About Bone Biologics<\/b>
\n
Bone Biologics was founded to pursue regenerative medicine for bone. The Company is undertaking work with select strategic partners that builds on the preclinical research of the NELL-1 protein. Bone Biologics is focusing development efforts for its bone graft substitute product on bone regeneration in spinal fusion procedures, while additionally having rights to trauma and osteoporosis applications. For more information, please visit\u00a0www.bonebiologics.com<\/a>.<\/p>\n

\n Forward-Looking Statements<\/b>
\n
Certain statements contained in this press release, including, without limitation, statements regarding the timing, implementation, and success of the Company’s pilot clinical study, the Company\u2019s development of rhNELL-1 and achievement of operational milestones, the ability of the Company\u2019s lead product candidate NB1 to provide rapid, specific and guided control over bone regeneration and show fusion success in humans, the ability of NB1 to compete in global markets, as well as statements containing the words “may,” “believe,” “expect,” and words of similar import, constitute “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements involve both known and unknown risks and uncertainties. The Company\u2019s actual results may differ materially from those anticipated in its forward-looking statements as a result of a number of factors, including, but not limited to, market and other conditions and risks generally associated with an undercapitalized developing company, as well as the risks contained under “Risk Factors” and “Management\u2019s Discussion and Analysis of Financial Condition and Results of Operations” in the Company\u2019s Annual Report on Form 10-K for the year ended December 31, 2025 and the Company\u2019s other filings with the Securities and Exchange Commission. Except as required by applicable law, we undertake no obligation to revise or update any forward-looking statements to reflect any event or circumstance that may arise after the date hereof.<\/p>\n

\n Contacts<\/b>\n <\/p>\n

\n CORE IR<\/b>
\n
(212) 655-0924
investors@bonebiologics.com<\/p>\n

\"\"
\n
\n \"\"\n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

Milestone strengthens manufacturing flexibility and supports pivotal study readiness BURLINGTON, Mass, Aug. 12, 2026 (GLOBE NEWSWIRE) — Bone Biologics Corporation (“Bone Biologics” or the “Company”) (NASDAQ: BBLG, BBLGW), a developer of orthobiologic products for spine fusion markets, today announces that the validated shelf life of its rhNELL-1 protein has been extended to 32 months. \u201cReaching a 32-month validated shelf life gives us greater flexibility in how we manufacture, store and distribute rhNELL-1 as we prepare for pivotal-study scale,\u201d said Jeff Frelick, Chief Executive Officer. \u201cWe have achieved each stability milestone on the timeline communicated to shareholders. By extending the period the product can be held before use, we believe this milestone supports more efficient lot sizing, inventory management and distribution … <\/p>\n

Continue reading “Bone Biologics Achieves 32-Month Validated Shelf Life for rhNELL-1”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-994052","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nBone Biologics Achieves 32-Month Validated Shelf Life for rhNELL-1 - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/bone-biologics-achieves-32-month-validated-shelf-life-for-rhnell-1\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bone Biologics Achieves 32-Month Validated Shelf Life for rhNELL-1 - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Milestone strengthens manufacturing flexibility and supports pivotal study readiness BURLINGTON, Mass, Aug. 12, 2026 (GLOBE NEWSWIRE) — Bone Biologics Corporation (“Bone Biologics” or the “Company”) (NASDAQ: BBLG, BBLGW), a developer of orthobiologic products for spine fusion markets, today announces that the validated shelf life of its rhNELL-1 protein has been extended to 32 months. \u201cReaching a 32-month validated shelf life gives us greater flexibility in how we manufacture, store and distribute rhNELL-1 as we prepare for pivotal-study scale,\u201d said Jeff Frelick, Chief Executive Officer. \u201cWe have achieved each stability milestone on the timeline communicated to shareholders. 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