{"id":992569,"date":"2026-08-10T07:06:08","date_gmt":"2026-08-10T11:06:08","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\/"},"modified":"2026-08-10T07:06:08","modified_gmt":"2026-08-10T11:06:08","slug":"apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\/","title":{"rendered":"Apogee Reports Second Quarter 2026 Financial Results and Recent Corporate and Pipeline Updates"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"center\">\n        <em>AbbVie to acquire Apogee for $135.11 per share in cash for total equity value of approximately $10.9 billion, positioning differentiated immunology portfolio to reach more patients worldwide<\/em>\n      <\/p>\n<p align=\"center\">\n        <em>Positive 16-week Phase 2 APEX Part B induction dose optimization results support planned advancement of zumilokibart into Phase 3 development in moderate-to-severe atopic dermatitis this year<\/em>\n      <\/p>\n<p align=\"justify\">SAN FRANCISCO and BOSTON, Aug.  10, 2026  (GLOBE NEWSWIRE) &#8212; Apogee Therapeutics, Inc. (Nasdaq: APGE), a clinical-stage biotechnology company advancing optimized, novel biologics with the potential for best-in-class profiles in the largest inflammatory and immunology (I&amp;I) markets, today reported second quarter 2026 financial results, recent corporate updates and pipeline progress.<\/p>\n<p align=\"justify\">&#8220;The second quarter marked a transformational period for Apogee,&#8221; said Michael Henderson, M.D., Chief Executive Officer of Apogee Therapeutics. &#8220;The strength of our Phase 2 APEX Part B results further demonstrated the potential of zumilokibart to redefine treatment for patients with moderate-to-severe atopic dermatitis while reinforcing its broader pipeline-in-a-product opportunity across inflammatory diseases. These results, followed by our strategic financing collaboration with Blackstone Life Sciences and the now pending acquisition by AbbVie, reflect the progress our team has made in advancing a differentiated immunology portfolio. We are grateful to the patients, investigators and employees who made these milestones possible, and we believe AbbVie&#8217;s scientific expertise, global scale and commercial capabilities provide the best opportunity to realize the full potential of these programs for patients around the world.&#8221;<\/p>\n<p>\n        <strong><br \/>\n          <u>Corporate Updates<\/u><br \/>\n        <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Pending acquisition by AbbVie positions portfolio for global development and commercialization:<\/strong><\/p>\n<ul type=\"circle\">\n<li style=\"text-align:justify\">In June 2026, Apogee announced that it entered into a definitive agreement to be acquired by AbbVie. Under the terms of the agreement, AbbVie will acquire all outstanding shares of Apogee for $135.11 per share in cash, representing a total equity value of approximately $10.9 billion. The proposed acquisition is expected to strengthen AbbVie&#8217;s immunology portfolio while advancing the development of Apogee&#8217;s differentiated pipeline of therapies for inflammatory and immunological diseases. The transaction is expected to close in the third quarter of 2026, subject to customary closing conditions, including shareholder approval and receipt of required regulatory approvals. <br \/>\u00a0<\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align:justify\">\n          <strong>Strategic financing collaboration with Blackstone Life Sciences:<\/strong><\/p>\n<ul type=\"circle\">\n<li>In May 2026, Apogee announced a strategic financing collaboration with Blackstone Life Sciences for up to $1.3 billion in flexible, non-dilutive capital to support the Phase 3 development and potential commercialization of zumilokibart. Combined with the company&#8217;s existing cash balance at the time, the financing was expected to position Apogee to achieve a self-sustainable financial profile through commercialization without the need for future equity financing.\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <u>Pipeline Progress<\/u><br \/>\n        <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>APEX Phase 2 Part B met all primary and secondary endpoints with high statistical significance; dose optimization results informed dosing plans for upcoming Phase 3 trials expected to launch this year:<\/strong><\/p>\n<ul type=\"circle\">\n<li style=\"text-align:justify\">In May 2026, the company announced positive 16-week induction dose optimization results from Part B of the APEX Phase 2 trial evaluating zumilokibart in patients with moderate-to-severe atopic dermatitis. The trial met its primary endpoint with 65.9% of patients treated with mid-dose zumilokibart achieving EASI-75 (41.9% placebo adjusted). Key secondary endpoints were also met, with IGA 0\/1 in 46.0% of patients, EASI-90 in 47.4%, I-NRS \u22654 improvement in 50.5%, EASI-100 in 16.5%, with very low disease activity (vLDA) in 20.6%, each demonstrating statistically significant improvements versus placebo. Zumilokibart was well tolerated, with a safety profile generally consistent with other agents in the class.<\/li>\n<li style=\"text-align:justify\">Based on these results, as well as findings from APEX Part A, the company selected the mid-dose regimen for planned Phase 3 initiation this year.\u00a0<br \/>\u00a0<\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align:justify\">\n          <strong>Apogee announced trial plans for expansion indications in EoE and asthma: <\/strong><\/p>\n<ul type=\"circle\">\n<li>The ELEVATE Phase 2a trial, an open-label, proof-of-concept study evaluating zumilokibart in patients with eosinophilic esophagitis (EoE), will initiate in 2H 2026. The study is expected to enroll approximately 30 to 50 patients and will assess dosing every three or six months. The primary endpoint is histologic response, including reductions in eosinophil counts, with additional evaluation of endoscopic findings and patient-reported outcomes.<\/li>\n<li>The ASPIRE Phase 2b trial, a randomized, placebo-controlled study evaluating multiple dosing regimens of zumilokibart in patients with moderate-to-severe asthma with elevated Type 2 biomarkers and a history of exacerbations, will initiate in 1H 2027. The study is designed to be potentially registrational and is expected to enroll approximately 500 patients randomized across dosing intervals of every three, six, or twelve months, or placebo. The primary endpoint is annualized exacerbation rate at Week 52, with additional assessments of lung function and symptoms.<br \/>\u00a0<\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align:justify\">\n          <strong>Combination pipeline continues to advance across AD and respiratory conditions for APG279 and APG273 with potential for improved efficacy and dosing:<\/strong><\/p>\n<ul type=\"circle\">\n<li>The Phase 1b head-to-head study evaluating APG279 (zumilokibart + APG990) versus DUPIXENT\u00ae in atopic dermatitis is ongoing, with interim data expected in 2H 2026.<\/li>\n<li>APG273 (zumilokibart + APG333), a long-acting IL-13\/TSLP combination, continues to represent a differentiated respiratory program supported by positive Phase 1 data for APG333, with additional plans to be announced in 2H 2026.\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <u>Second Quarter 2026 Financial Results<\/u><br \/>\n        <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Cash Position: <\/strong>Cash, cash equivalents, marketable securities and long-term marketable securities were $1.3 billion as of June 30, 2026, compared to $621.2 million as of June 30, 2025.<\/li>\n<li style=\"text-align:justify\">\n          <strong>R&amp;D Expenses: <\/strong>Research and development (R&amp;D) expenses were $67.3 million for the quarter ended June 30, 2026, compared to $55.7 million for the quarter ended June 30, 2025. R&amp;D expenses increased primarily driven by the continued development of our zumilokibart program and higher personnel and equity-based compensation expenses associated with the growth in our research and development team.<\/li>\n<li style=\"text-align:justify\">\n          <strong>G&amp;A Expenses: <\/strong>General and administrative (G&amp;A) expenses were $24.3 million for the quarter ended June 30, 2026, compared to $17.5 million for the quarter ended June 30, 2025. G&amp;A expenses increased primarily due to increases in personnel-related expenses and equity-based compensation, primarily driven by increased headcount and an increase in the fair value of equity awards granted. These increases are the result of the company\u2019s expansion of operations to support the growth of its business.<\/li>\n<li style=\"text-align:justify\">\n          <strong>Net Loss: <\/strong>Net loss was $85.9 million for the quarter ended June 30, 2026, compared to a net loss of $66.1 million for the quarter ended June 30, 2025. Net loss increased primarily as a result of higher R&amp;D and G&amp;A expenses as described above.<\/p>\n<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>About Apogee<\/strong><br \/>\n        <br \/>Apogee Therapeutics is a clinical-stage biotechnology company advancing novel biologics with potential for differentiated efficacy and dosing in the largest I&amp;I markets, including for the treatment of AD, asthma, EoE, Chronic Obstructive Pulmonary Disease (COPD) and other I&amp;I indications. Apogee\u2019s antibody programs are designed to overcome limitations of existing therapies by targeting well-established mechanisms of action and incorporating advanced antibody engineering to optimize half-life and other properties. Zumilokibart, the company\u2019s most advanced program, is being initially developed for the treatment of AD, which is the largest and one of the least penetrated I&amp;I markets, as well as asthma and EoE. With five validated targets in its portfolio, Apogee is seeking to achieve best-in-class efficacy and dosing through monotherapies and combinations of its novel antibodies. Based on a broad pipeline and depth of expertise, the company believes it can deliver value and meaningful benefit to patients underserved by today\u2019s standard of care. For more information, please visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=c9bupEA1dUv0oU1ftUMZ_OzjHPuBrSP-l6aRlB0bxdB4Mh8wUVafpnKgnyUbhDgPL9ZvKL4HUDKyxLcwjCkqziVLduPvseTeUkaDhiYDsKKlLawBrPJeVLKLUNwyfOBVmu6BthDVZ-uFzLktJvEAB6gf6SngUXF5JbB6HFXHKnrpakVvPTmpTa9HLAnMRfox6ZL1ddNUhjymDydyZFjLHaWrbQqvoOM1klumWiTu3aWbb3JwNhhviiTTSErB-hFVRwuQVBadrQbUKcqYh3Zj_z6p0XcNJ6i05qR49YbCoLkfNUjKZIiue3I6nL7y86GvQwAd0rIJda87Vp9Wt9KMdeI_Hy_z0-wFCgnFkMWYQRLWbxhOD_SMPAH1uAazmWSZ_6De3Kblt9FGnu5D625oA43JpY4u8uDyG8cKwMer9hu2OWvXNFxYQZiBOdw62uQm\" rel=\"nofollow\" target=\"_blank\">https:\/\/<\/a><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=c0vNUhPEADdMTTBwx6odY14W83EEIsf0DZ-Kef3Eqo-x7PXtWW1aMk0BxUqkR4ejGf5bC9jBFSog54hplYc0ZJXF0awFcjdWrFfspjPLvO2V2mDJJRC9ftdqzyAO07W4GwH7eJuslAP39w2YvTLoMi8iVKOgBvFdKOP84S_yPu5fhle1uFpqMsW8fh-UoR_wXVgaR4j0hUyoHI0mHgJlLmw9IYGKtDk1QCco8adxzsXGud1QTjWXKjTKZuld8OZVxqQQ1TCsVsNRA4-N1hiqjUTqLtqxv5U5XkBmayx9R2HITGGBoA-bNXTf31Sq1zWDpgQ3CPwRj7NTFYBVBV0B1AhK4kRvFFPjRTTE821g0b0ZySko_5sG_nIbz6VpOZjqYIehT_xcZfIF5026jOMbsx1--wd0F5MjYG_D7JspIrq5R584xlrUMRXy8EMSfmOHluSl64Y2dk8dXsK3mejwIw==\" rel=\"nofollow\" target=\"_blank\">apogeetherapeutics<\/a><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=dSEQDG36XH9NsBrCEoocjTqOglxCidrgToLd-BLJqNZUka5Yn8eBvGvSdw4dDV2ALVViG4HNqwIXlVPI2-HjCBbaHECD-FeO0ucqhfMhYcN_DnVHKzrAr8Z7WmyBd5eOLOQl8z5WGOD0wE2jIhBs1r9vzZIX7XgeG0KKb71eFmf19lbTYCTZaFTB38FIzFega_zCszPvbDzcY0Ch-FjaS3omOAiramzHA2MnBDB_CkBOLqC_mpqo3MVxKX5glipeH3uwyqiMVgcF70w9uFAqoU1gAaiAmL1phw1xPe8tCf10an9H9FxrwKqdP8EoJoe5uYOEhMcdAcO37gXZmHRGXR-IHdozfnaQcnZl8g1MniSV0iEDVau8Njct2OMqfEoZ_Go2NWbj_SpWAemm8sB53-XMy9QNQdhj07qgthWXH66TTk9jLd-DEbyHvHvJlQC8\" rel=\"nofollow\" target=\"_blank\">.com<\/a>.<\/p>\n<p align=\"justify\">\n        <strong><br \/>\n          <u>Cautionary Statement Regarding Forward-Looking Statements<\/u><br \/>\n        <\/strong><br \/>\n        <br \/>This communication contains statements that constitute \u201cforward-looking statements\u201d within the meaning of the Private Securities Litigation Reform Act of 1995, Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, each as amended. All statements other than statements of historical fact, including statements regarding market and industry prospects and future results of operations or financial position made in this communication are forward-looking. In many cases, you can identify forward-looking statements by terminology, such as \u201cmay,\u201d \u201cshould,\u201d \u201cexpects,\u201d \u201cintends,\u201d \u201cplans,\u201d \u201canticipates,\u201d \u201cbelieves,\u201d \u201cestimates,\u201d \u201cpredicts,\u201d \u201cpotential,\u201d \u201ccontinue\u201d or the negative of such terms and other comparable terminology. Statements in this communication that are forward-looking may include, but are not limited to, statements regarding the benefits of the proposed acquisition of Apogee\u00a0Therapeutics, Inc. (\u201cApogee\u201d) by AbbVie Inc. (\u201cAbbVie\u201d) and the associated integration plans, anticipated future operating performance and results of Apogee, the expected timing of the closing of the proposed acquisition and other transactions contemplated by the merger agreement governing the proposed acquisition (the \u201cMerger Agreement\u201d), and the potential of zumilokibart (APG777) and other Apogee pipeline assets.<\/p>\n<p align=\"justify\">There may also be other statements of expectations, beliefs, future plans and strategies, anticipated events or trends and similar expressions concerning matters that are not historical facts. Readers are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, many of which are difficult to predict and are generally outside Apogee\u2019s control, that could cause actual performance or results to differ materially from those expressed in, or implied or projected by, the forward-looking statements. Such risks and uncertainties include, but are not limited to: the occurrence of any event, change or other circumstance that could give rise to the right of Apogee or AbbVie or both of them to terminate the Merger Agreement, including circumstances requiring a party to pay the other party a termination fee pursuant to the Merger Agreement; the failure to obtain applicable regulatory or Apogee stockholder approval in a timely manner or otherwise; the risk that the proposed acquisition may not close in the anticipated timeframe or at all due to one or more of the other closing conditions to the transaction not being satisfied or waived; the possibility of competing acquisition proposals for Apogee; the risk that there may be unexpected costs, charges or expenses resulting from the proposed acquisition; risks related to the ability of Apogee and AbbVie to successfully integrate the businesses and the possibility that such integration may be more difficult, time consuming or costly than expected; risks that the proposed transaction disrupts Apogee\u2019s or AbbVie\u2019s current plans and operations; the risk that certain restrictions during the pendency of the proposed transaction may impact Apogee\u2019s ability to pursue certain business opportunities or strategic transactions; risks related to disruption of each company\u2019s management\u2019s time and attention from ongoing business operations due to the proposed transaction; the risk that any announcements relating to the proposed transaction could have adverse effects on the market price of Apogee\u2019s and\/or AbbVie\u2019s common stock, credit ratings or operating results; the risk that the proposed transaction and its announcement could have an adverse effect on the ability of Apogee and AbbVie to retain and hire key personnel, to retain customers and to maintain relationships with each of their respective business partners, suppliers and customers and on their respective operating results and businesses generally; the risk of litigation that could be instituted against the parties to the Merger Agreement or their respective directors, managers or officers and\/or regulatory actions related to the proposed acquisition, including the effects of any outcomes related thereto; the risk that zumilokibart (APG777) or APG273 and other Apogee pipeline assets may not demonstrate the anticipated success, safety, or efficacy in ongoing or future clinical trials; the risk that positive Phase 2 and Phase 1b interim results for zumilokibart (APG777) may not be predictive of results in later-stage or larger clinical trials; challenges to intellectual property; adverse litigation or government action; competition from other products; difficulties inherent in the research and development process; risks related to unpredictable and severe or catastrophic events, including but not limited to acts of terrorism, war or hostilities, cyber attacks, or the impact of any pandemic, epidemic or outbreak of an infectious disease in the United States or worldwide on Apogee\u2019s or AbbVie\u2019s business, financial condition and results of operations, as well as the response thereto by each company\u2019s management; and other business effects, including the effects of industry, market, economic, political or regulatory conditions.<\/p>\n<p align=\"justify\">Also, AbbVie\u2019s and Apogee\u2019s actual results may differ materially from those contemplated by the forward-looking statements for a number of additional reasons as described in AbbVie\u2019s and Apogee\u2019s filings with the Securities and Exchange Commission (the \u201cSEC\u201d), including those set forth in the Risk Factors section and under any \u201cForward-Looking Statements\u201d or similar heading in AbbVie\u2019s and Apogee\u2019s most recently filed Annual Report on Form 10-K filed on <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=7udUZekDR4QvUKgjCcaS5PlkvjmrdoBWnNRRQBY4kaoSNqiFBtEZeDcQFF7_Y7qkeGBVMnHXNADEmrRzRwm6NAubUbYo7NcyVkS3cJG5vB-P8XFGbtyIQjzA9BoFOHPN_1jIhw2aLkA434pu826yMS2ApzrCkpCELHYJGKD0OcMYpexa-Ios4rcf6LU70mOTlMl5vLZWZzb_KAKne90uDFyt1hjO9eXhf8Lp5B-HSZg3SZZbiuOodvo-YxBt5ZFWDf69lpE5sBxB8PLioh5sX3DD2j1CYiCDEeM8ec_BLJOUkPVNVKDkNj4VNYMVM5kpuVXuelsCoSBfKJIyill6E4F3FO6SBbWWzO4_QgPmChVSlev2AlcZQwnotCmUi20t0qBfHmEABTi7cCAnu2sxSVO4JI6wEec7O2-nPYBPhNXu6Q4YPFi-8QZykgpPmGtYpHbWiMh1Ne9h-WxA3w3v4Ih3NQb3wkl93ODqoB5N-J9QzDL4AX_ccQeo_rqf9qnaAi7WTa-j8pZzKliY15CL2hsRSLUycXKphvcZGgGyieY=\" rel=\"nofollow\" target=\"_blank\">February 20, 2026<\/a>, and <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=yAN_wVn6D8AYU-Wced0CVfox9TwOGFZ5bi2hxGGMGlT0uwqBcI4ui4bK5L5AInZlkLXuxpKPvKUOHide28FgIW1s12eMTUWa_XF2-DPIUmvVwJRx-tMNpmzwjv7dcub3E9HCx8sxyc33E0jMDkqBOoszVd5F0Nfshw3Mm7JczBu9pAcjXB-5TPYS7iVKABbnPfOKpv1YNIjo0LvT91HbMGgor18D8-1Xsdc34LLQEv61AP1ER2SCo1SGeLp9TbEel5vKHkzOCaRkj0HJILoIrmmA_iPbbbUpRGAeLJiBpzoFp88qbL2uzIDn9FkMDiIZO6Dx808xNDdU5msQse_auS0oHhS7dzEj6Kks79NpjoO7dV4FdtcDbmXIOvlCbLgZnsJpT7K4q9eBVSO7E95ZHCgr_Doybjb9r8AbKsV3ATMVaGDjFk4cK47dm3PZaQIot_idml76RNL4Cw4TR9d6A5JiR0nvj9zpC1o8fBhoV4ATyBebyW-EovWvHLuHhC2TwpL2csn8lCPAi74oG47Erw==\" rel=\"nofollow\" target=\"_blank\">March 2, 2026<\/a>, respectively, and subsequent Quarterly Reports on Form 10-Q and Current Reports on Form 8-K.<\/p>\n<p align=\"justify\">AbbVie and Apogee have based these forward-looking statements on their current expectations and projections about future events. Although the parties believe that the assumptions on which the forward-looking statements contained herein are based are reasonable, any of those assumptions could prove to be inaccurate. As a result, the forward-looking statements based upon those assumptions also could be incorrect. Except to the extent required by law, AbbVie and Apogee undertake no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.<\/p>\n<p align=\"justify\">\n        <strong><br \/>\n          <u>Additional Information and Where to Find It<\/u><br \/>\n        <\/strong><br \/>\n        <br \/>This communication is being made in respect of the proposed transaction involving Apogee and AbbVie. Apogee has filed a definitive proxy statement and a form of proxy card with the SEC in connection with the solicitation of proxies for the special meeting of Apogee\u2019s stockholders (the \u201cDefinitive Proxy Statement\u201d). This communication is not a substitute for the Definitive Proxy Statement or any other document that may be filed by Apogee with the SEC.<\/p>\n<p align=\"justify\">BEFORE MAKING ANY DECISION, APOGEE STOCKHOLDERS ARE URGED TO CAREFULLY READ THE DEFINITIVE PROXY STATEMENT (INCLUDING ANY AMENDMENTS OR SUPPLEMENTS THERETO), AND ANY OTHER RELEVANT DOCUMENTS FILED OR TO BE FILED WITH THE SEC IN CONNECTION WITH THE PROPOSED TRANSACTION OR INCORPORATED BY REFERENCE INTO THE DEFINITIVE PROXY STATEMENT WHEN THEY BECOME AVAILABLE BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION ABOUT THE PROPOSED TRANSACTION.<\/p>\n<p align=\"justify\">Any vote in respect of resolutions to be proposed at the special meeting of Apogee\u2019s stockholders to approve the proposed transaction or other responses in relation to the proposed transaction should be made only on the basis of the information contained in the Definitive Proxy Statement. You may obtain free copies of the Definitive Proxy Statement and other related documents (when available) filed by Apogee with the SEC at the website maintained by the SEC at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=G1L-jv20tdDTpCg6toi9du_lMaKeJTguLbVfFQrzkkosYzHuYks8JwQXbD3dRauam4r0n6fBn_FFgfuVG2pfRofgmCobNW-ddXyb50RCZpB9rhM9chXRjgjmGVEzSFy7WQPx-Skc_LK-H4Z5hW1lAeEPyNkg6iavWNwo1SVC4KAYkjYT9w9t3Z1ZMJgqsHjjQQcReUsbSmk3lEO9B1o8fxRthA3Txcww5oPVyT_dqamYi4yRpAmsZ1YvsZzzbjSWGKha10OhgzPNrpjKVExHRHS3JGgzLeDy-8AxzHCkPOEUwqSh4HKUAJGuMn2GWJHTsCO5h9deajE7LM60s-o3Vow8mlQOOvxA3rmIbS2_cCZBxUSqAvRbC_HeAS-NjHI5Jji7-wgcwijsGrN9_OVTco5_99xtRUgjSWcnFVIvyqY=\" rel=\"nofollow\" target=\"_blank\">www.sec.gov<\/a> or by accessing the Investors section of Apogee\u2019s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=c9bupEA1dUv0oU1ftUMZ_Gnmkl9cEYgnnDVWYEF3eaV3JGtYSZ3k7CFSGdvMKnqhhY1ULUAJrecjwxkZAr88vwwV9z9cnm5SKPf4l3C1pvN4zravzZ9-qcg5eD57v4ZeNjM7CIXUj0xALt3r5-rex0VL8gKeKpBzujB6qCjdu4Vm-URv-HkdPomjNkvWd18OKAHlqO0epfphHpvqs67EyRTf4yjJapH1TdBDDx6C3Gm-Z96C49Np5wDm77FA6h7J6xzWkj7WFOzALtR5fxq9v_6IFAjLBt5ijW64MXMRhA5w5ffu5P6Lig8hQ9dilSf-bHH-EOapiQOx8ifDhXyTNEK3TXqyVUkOv5efso_5kGfXIVJfhhJ6ziRdtHvtS3hIS2pRlXPoFHu27KnT2wcxUYgGE_Qo3v4b4hAisVdSzOqdnzhyhSRMEDcF1Pcpm3j84roJQSO7zRI_-8QGP57rKEj9sAmBVcscsBs_UgIyYtbVJYWcUnNQz_QHxkYR9_1_\" rel=\"nofollow\" target=\"_blank\">https:\/\/investors.apogeetherapeutics.com<\/a>.<\/p>\n<p align=\"justify\">\n        <strong><br \/>\n          <u>No Offer or Solicitation<\/u><br \/>\n        <\/strong><br \/>\n        <br \/>This communication is for informational purposes only and is not intended to, and does not constitute or form part of, an offer, invitation or the solicitation of an offer or invitation to purchase, otherwise acquire, subscribe for, sell or otherwise dispose of any securities, or the solicitation of any vote or approval in any jurisdiction, pursuant to the proposed transaction or otherwise, nor shall there be any sale, issuance or transfer of securities in any jurisdiction in contravention of applicable law. No offer of securities shall be made except by means of a prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended.<\/p>\n<p align=\"justify\">\n        <strong><br \/>\n          <u>Participants in the Solicitation<\/u><br \/>\n        <\/strong><br \/>\n        <br \/>Apogee, AbbVie and their respective directors and executive officers and certain of their employees may be deemed to be participants in the solicitation of proxies from Apogee\u2019s stockholders in connection with the proposed transaction. Information regarding Apogee\u2019s directors and executive officers is set forth under the captions \u201cThe Merger\u2014Interests of Apogee\u2019s Directors and Executive Officers in the Merger\u201d and \u201cSecurity Ownership of Certain Beneficial Owners and Management\u201d in the Definitive Proxy Statement filed with the SEC on <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Dyl6kCvTrAIEfAXtGDeEwVWlMAs1iuYZSbZbDckIxXbVkE-v-cwXXMDwk4wD4Zsm8YR4eosYziMuswOQD-IZcA9gcq2UB64apdpgoS3GA2LhOn3zZk5W5rC41X6LO6VfdLKFDW-TKkl3HGI6wHRs6ZRJqE60lwURbx_0bjLzeSkptSMJMpNqY9Ufg-km_zwf9J_JUMAumY11VYP82y5Jcwczpud6JBRgP1ggVG0d10aZfiY4PjpfYu5c7mo5c1XvaIRzoALXdr1jW4VHSnvz8KSN6KuvS7gngsZM45qtbpV7Tdn9IzhH0pBKNeoSz9ws4IziPmw4kID71FNf07hbye8NjbQ1X17349D8qkRtEEyzyxdC3M1ch-4JNBb-T9uHdEYBSAk5Q4lfJWqekHc-0AoC5kWGK75-6txJN5z4bKikBN52KMKGhrNgvp3SToykmpSIU0JICkXXZNdImLhtS-TA7RKk-XlupvINov9e8fcU3B19NIYZhEX8AMnHLBVMuWal72pJSQ53ikq7hcf9PQ==\" rel=\"nofollow\" target=\"_blank\">July 13, 2026<\/a>; under the captions \u201cProposal 1: Election of Directors,\u201d \u201cCorporate Governance,\u201d \u201cExecutive Officers,\u201d \u201cExecutive Compensation\u201d and \u201cCertain Information About Our Common Stock\u201d in the definitive proxy statement for Apogee\u2019s 2026 Annual Meeting of Stockholders, filed with the SEC on\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=DqWUXdomtn2QXUfUixjn38D94GKhm1-kgRLbLdNtCCnpSUhEu2-4Y5Kn320PYCFyj__DgafI0PNmAqCTzjaBNma4QtHosiC1UHAzqYA7ZhmAU_-shtcIWJwAJ4cmPsjtcu4zAujghnax7cV-MaEsEiU0B5qhC0N1-NFeMgwzRp3xjqMkVEB6vNEP7Qp0wmnIlpCzxu6xwNt-RRotrOp3MMgq8gvlms1T32izezCCSkBeTG1jtAmmjLzuc1R_w6iyhn9tXri3q6iulMIHyC91F1pfb5zYqSDmQp-mF7aVHOz4O5TuxRfxLKateLfK4y1OZ3npeIokQSyewjwQ90c_9BL0w9n4pQVcdQRQSgLOjfyTr0FLl1LwcdjfKOCtbdxKVhs75XuObJfhUcvEBGo0MhhX-miedvHXPCeSL5xMXYe9sGobzF55Kvz5CxLJizZ2K9xWsWsqR-pC3-zwy3MnWFPsYkGTTZd93sfaW7zs5c1dJTVjFghlhQYldk7DY8kKMSvxy9HEJ43xujeAFWbOEg==\" rel=\"nofollow\" target=\"_blank\">April 24, 2026<\/a>; and in Apogee\u2019s Current Reports on Form 8-K, filed with the SEC on\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=DqWUXdomtn2QXUfUixjn3xyHcuI7jGLkxHfWEfDbP_t6cEgAYAP6Eexzh3fbV9UxEsfHa1g1MXnIdINnWAIvUL6d8XnnIt3h4nzt4XJGgTuA0-fIcAtkzIzmSP8gXZ8qYsHf8cEjnjWK-VBYztnH7kvc-1mVL-WX-9KOfmOfOQhZz2kr0d-G5QMvD4YEw4-bQ5n_2Z32JuayvTWwJSPPYQKbfRifiRzOyRdKyi5rtyJclGywHhksyLfWooVpzCE_Yp9E_6QqinfA0FU9hZZxJOhUAsIeuk5DLXOoMKQeMQgWauzvbjDUnmppqb2yS60unhOysKJnFftGZ3lIG7hT7Zjsia_F0A8RhNfTn2kh9uQBvdJVdPAutC_aZcfE48tOcaSCF1jSV2Ww-xy3VdIry_61c0z9eQj672krmW-HlVkRUOgbmOWzSRn76weeNZ9VTxmP4NtWznI9aw55Hklx1W79Z5X4GuoF3CBLVeoXU5FH4YykIXbFs3NeSemq5nkqrUkpf9FUc9RlBUlRU_EM2g==\" rel=\"nofollow\" target=\"_blank\">April 24, 2026<\/a>, and\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=B6jId5HrSFJ0NApQlw6sZuWfrDFb3N42lvhcoZ4SOg7639GNuY_5SFdT9YMvQQjsxJEesI3Cuw_NqvjlMgi1KaM35mYFYdixuyDY9LfL17QJz4AQ1WWonMggRSQLTYJzNiTyS9JtHd6pMy_091TK60U27zEEI_btX8TuCLCctuTU5Fbw6giTIbzneqPlzIOrlgiwLMnzjbCJVheb9AY91eIptwIfc5gEFF6Qb9_jdyahWNbzQOhySApP2vXQGtTbPCgTs6GxKxvw7CEjTCR_Jzli2BQs2I1ac5IhgtAmUTSe85wESCLuO-DIL3i-Fz9sahWMvbcWc1GK8Slf-NEpSMVLr32O0hc9uCrSZc4e-EyOYCmik0PGsFjv-vkY_7vZcJK4UazwonT5r9NFcLMGHBKoQ8BnJOH8a20G0ZRLd7L_n2FZxWaVR2SCofeshxrsrYxB9aENFksB8_lXZpMdmL60jLqK9iZsIRrO8Om4OjIukRrpSZh0SWqV6ShoNX74-7A-XqeSYrMr5krdBWj0IQ==\" rel=\"nofollow\" target=\"_blank\">June 12, 2026<\/a>. Information regarding AbbVie\u2019s directors and executive officers is set forth under the captions \u201cInformation Concerning Director Nominees,\u201d \u201cThe Board of Directors and its Committees,\u201d \u201cDirector Compensation,\u201d \u201cSecurities Ownership\u201d and \u201cExecutive Compensation\u201d in the definitive proxy statement for AbbVie\u2019s 2026 Annual Meeting of Stockholders, filed with the SEC on\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=yAN_wVn6D8AYU-Wced0CVaFY8csMl3jhyoFA6hSvfMP2vsPhWgKCjvdZZxO-2kn3yUEHlw-LbZ3iXrRSl9ziIOu8-C8JYhrYih7bzhC-kPjKDxC4CrsJ4TL96Kdtjeg3zturymwRokoEMxzMgiOt3LJzBRYe_zEjro-MZ-dOj6IABS7aqUNMHMFgnhwLztAFIQy70BVuv_DaHoPCdWSeRWHRU1toMujtfYQKXt5bV9K99ZPBg_nhjSa5aS8_7C8PcyNk2Aoy6Sfwp7d6k3mgk19cdSETIAW6JCikh96rtgUoM-WSdeg_RbyLnTrip0aAKUs72LiElQYLBBT1iDjr-NWdk-xzPbyyXoKIXSvIMUqbRFHqTLgqIKMZgaRaUf8fFQBCaTVBXjQcwB-c915uBT8wa7hZxePNSdEP_s5eMH_KuRotBbk-ThtWByNOKPTCrS0tMzLn1yiGYPD_BEEaepdK53yisml7H5kwsDCxbhyULH5uX6OokUtgK-G_4KPfTTLq77C0UVpGCeaClGpy6fzBibesgkPDtXjl0zLVPgs=\" rel=\"nofollow\" target=\"_blank\">March 23, 2026<\/a>; and in AbbVie\u2019s Current Report on Form 8-K, filed with the SEC on\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=TPHd8jyk-leeEy6z7KjIIhexCQuur43fc0bbSloMtJdPxgtqsYGxYGrm-4F9uWHVwQ_M2FtkOhOMy4iJI4YMZgEkcD_3OC6MhGCqbL1CYeXUofRO0QXy4k570ro8e0ovXdpomFsLfq7SYo3fZkpxGMWwAsDs9R4vS-qf9gCi5bJ1zQGXfI-bhD6E-iRio8FDV0BqJ8IBjYCHOK6tieXe5Hivx3PH5zseD7KQuOgAVK368umII7l31KL5HHGNmrVkxMfDrjQ80rmebqDGdfbV86hqXjoQqNdXUh30UFwuplVDJrN30tKni5Z9hdyb4h4wIdUZXjLXTe55v5j04D_GcEdJ11rdw8UbuYUe8eRehStQSBIGVgXnR9DPaV0SVonUIBPU_Lu97ILcU-iRg0VfFluk8kW8gqEGvstf02KaprD7dHMhj2hRoBFhBNf-EknUXMOE9m-Ov7pzzpn-wZd1VS3hpssSloOvgOHZk7OCa2ZxoVBuOQ7QS0WVjOTtHVKOtl5Dr4C7s_1al8LS1zuvFw==\" rel=\"nofollow\" target=\"_blank\">May 12, 2026<\/a>. To the extent holdings of Apogee\u2019s securities and AbbVie\u2019s securities by their respective directors or executive officers have changed since the amounts set forth in such filings, such changes have been or will be reflected on Initial Statements of Beneficial Ownership on Form 3 or Statements of Beneficial Ownership on Form 4 filed with the SEC. These documents may be obtained free of charge from the SEC\u2019s website at www.sec.gov or by accessing the Investors section of Apogee\u2019s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=c9bupEA1dUv0oU1ftUMZ_Gnmkl9cEYgnnDVWYEF3eaV3JGtYSZ3k7CFSGdvMKnqh95GWJ1GuNMmOXv4DdOqohheP8_Rttf8EMKUAAG5l_g6AajbHGzPfCuO-pN_Wrs_GkVHBbYm_vaoArPAcxP8Ax_BuuEDJHu433OHJV0BZ86ulB11kObkqYcisj0xszd-3KNvkZR8TX36CE9OLoU2xApr_Xmxu81yOu49D4hLEiHNVK4XWzmy8lMCHCKP8TNsbPFlC4Uis2Y__1g8IEC8t1WU08j8gUjpawm8gD76u0z_fTDbK7ByRYPD8DiyH5whSTQhBKw_AS-fGpLP2zotCDGaFEzqP4ZeH8LFeP9FUZtrcP9odxCNFUikHhn9WhEkp7u5-jyTqFFCwU1rRCeC42EKt_zrGfJrU8bT8cAfogr0imgimtui0KVUj5FRx2NglgZ3ktxbPcDEQ586kC7Slun4YQINO32UhMb4g3fXtNk7zr7ljviVxHD3NpR2XnH3V\" rel=\"nofollow\" target=\"_blank\">https:\/\/investors.apogeetherapeutics.com<\/a> and the Investors section of AbbVie\u2019s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=c9bupEA1dUv0oU1ftUMZ_PrlR223AaTMh4EIs-m-DgWVb0wjcQVUESWwI5xN94RVCliO6zErWywNTovhRMlQcrijdDcHC9_u2vJ4gmroR9aWcdTRMFCW0wKf3pPXEIBNqP6znxhJSu5MCL_PTjo5m9VeV36dJlkxKMPjoTZJ35zSLqTIAChC_IIRydP7KXdr1kX1SmfQjFw_XLwda1v2PcaKG_uTULsLSKLOxaBe1tPnXXAcdZcfYM35Sa8rc94xUCbHL_CShheAuX1efUvPOAKWLXYxZ-qfAtYLWGhfQJfr2NQXeKr_Syv5Kg2NqWSRbazHMptHiLcSNPJoNz-oaHoVzr4HWlOAYqwb5b6aCNSv56bED-Qt69p-OdXh3QmD5QA8uczoI3a_0IOb_paLNoNLt6g_gV9gC8r1Asqo6jbeQunTms3PcIe5bGmwhA-hDdVxD3Addq0vDNObysli7A==\" rel=\"nofollow\" target=\"_blank\">https:\/\/investors.abbvie.com<\/a>. Additional information regarding the interests of participants in the solicitation of proxies in connection with the proposed transaction will be included in the Definitive Proxy Statement and other relevant materials Apogee may file with the SEC.<\/p>\n<p align=\"center\">\n        <strong><br \/>\n          <br \/>\n        <\/strong>\n      <\/p>\n<table align=\"center\" style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td colspan=\"8\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td colspan=\"8\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>APOGEE THERAPEUTICS, INC.<\/strong><\/p>\n<p>            <strong>CONDENSED CONSOLIDATED BALANCE SHEETS<\/strong><br \/>\n            <br \/>\n            <strong>(UNAUDITED)<\/strong><br \/>\n            <br \/>(In thousands, except share data)<\/td>\n<\/tr>\n<tr>\n<td colspan=\"8\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>JUNE <\/strong><br \/>\n            <strong>3<\/strong><br \/>\n            <strong>0<\/strong><br \/>\n            <strong>,<br \/><\/strong><br \/>\n            <strong>2026<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>DECEMBER\u00a031,<\/strong><br \/>\n            <br \/>\n            <strong>2025<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Assets<\/strong>\n          <\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Current assets:<\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:73%;width:73%;min-width:73%;vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Cash and cash equivalents<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">105,571<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;text-align: right;vertical-align: middle;vertical-align: bottom\">131,549<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Marketable securities<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">866,355<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">598,643<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Prepaid expenses and other current assets<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">19,807<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">11,166<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total current assets<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">991,733<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">741,358<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Long-term marketable securities<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">321,943<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">172,730<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Property and equipment, net<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">4,822<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">5,688<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Right-of-use asset, net<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">6,708<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">8,687<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Other non-current assets<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">10,607<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">8,671<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Total assets<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">1,335,813<\/td>\n<td style=\"border-bottom: double black 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">937,134<\/td>\n<td style=\"border-bottom: double black 3pt;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Liabilities and stockholders\u2019 equity<\/strong>\n          <\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Current liabilities:<\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Accounts payable<\/td>\n<td style=\"vertical-align: bottom\">$<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">3,080<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">$<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">1,221<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Lease liability<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">2,365<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">3,504<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Accrued expenses and other current liabilities<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">32,065<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">23,181<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total current liabilities<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">37,510<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">27,906<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Long-term liabilities:<\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Lease liability, net of current<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">4,468<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">5,345<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Revenue share liability<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">99,231<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u2014<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Total liabilities<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">141,209<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">33,251<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Stockholders\u2019 equity:<\/td>\n<td colspan=\"3\" style=\"border-top: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Common Stock; $0.00001 par value, 400,000,000 authorized, 75,611,894 issued and 75,339,499 outstanding as of June 30, 2026; 400,000,000 authorized, 69,038,943 issued and 68,401,349 outstanding as of December 31, 2025<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">1<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">1<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Additional paid-in capital<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">1,918,830<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">1,464,561<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Accumulated other comprehensive (loss) income<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(2,503<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">1,080<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Accumulated deficit<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(721,724<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(561,759<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total stockholders\u2019 equity<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">1,194,604<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">903,883<\/td>\n<td style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Total liabilities and stockholders\u2019 equity<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">1,335,813<\/td>\n<td style=\"border-bottom: double black 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">937,134<\/td>\n<td style=\"border-bottom: double black 3pt;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<\/table>\n<p align=\"center\">\n        \n      <\/p>\n<table align=\"center\" style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td colspan=\"16\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td colspan=\"16\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>APOGEE THERAPEUTICS, INC.<\/strong><\/p>\n<p>            <strong>CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS<\/strong><br \/>\n            <br \/>\n            <strong>(UNAUDITED)<\/strong><br \/>\n            <br \/>(In thousands)<\/td>\n<\/tr>\n<tr>\n<td colspan=\"16\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"7\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>THREE MONTHS ENDED <br \/>JUNE 30,<\/strong><br \/>\n            <strong><br \/>\n              <br \/>\n            <\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"7\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>SIX MONTHS ENDED <br \/>JUNE\u00a030,<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2026<\/strong><br \/>\n            \n          <\/td>\n<td style=\"border-top: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2025<\/strong><br \/>\n            <strong><br \/>\n              <br \/>\n            <\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2026<\/strong><br \/>\n            \n          <\/td>\n<td style=\"border-top: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2025<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Operating expenses:<\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:45%;width:45%;min-width:45%;vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Research and development<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">67,301<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;text-align: right;vertical-align: middle;vertical-align: bottom\">55,703<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">128,120<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;text-align: right;vertical-align: middle;vertical-align: bottom\">102,090<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">General and administrative<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">24,342<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">17,462<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">46,295<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">34,171<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Merger transaction costs<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">4,361<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u2014<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">4,361<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u2014<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total operating expenses<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">96,004<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">73,165<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">178,776<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">136,261<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Loss from operations<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(96,004<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">(73,165<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(178,776<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">(136,261<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Other income, net:<\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Interest income, net<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">11,808<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">7,141<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">20,548<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">14,981<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Interest expense<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(1,580<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u2014<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(1,580<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u2014<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total other income, net<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">10,228<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">7,141<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">18,968<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">14,981<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Net loss before taxes<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(85,776<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">(66,024<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(159,808<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">(121,280<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Provision for income taxes<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(78<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(72<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(157<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(155<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Net loss after taxes<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(85,854<\/td>\n<td style=\"border-bottom: double black 3pt;border-top: solid black 1pt;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(66,096<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double black 3pt;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(159,965<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double black 3pt;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(121,435<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double black 3pt;vertical-align: bottom\">)<\/td>\n<\/tr>\n<\/table>\n<p>\n        <strong><br \/>\n          <br \/>Investor Contact:<\/strong><br \/>\n        <br \/>Noel Kurdi<br \/>VP, Investor Relations<br \/>Apogee Therapeutics, Inc.<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=KHp5ULkleO9i0ivK_qee8XuMTr_8I1imy_gjzIPbQtzd2yMUZeDYy7IefHys4xjj5K-Hhns-3W58iEs9B1-bNoGGn2NfNCbxyJztOtM7bOmJBzn07znbOLCcfFLbxCX5QBAw966seIQwEADJewTRJQ==\" rel=\"nofollow\" target=\"_blank\">Noel.Kurdi@apogeetherapeutics.com<\/a><\/p>\n<p>\n        <strong>Media Contact:<\/strong><br \/>\n        <br \/>Dan Budwick<br \/>1AB Media<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=-uq-N3GNhtZ1fqKIh5xQAMwmyn6ZThcfl_k1tOGl23nQu79fFRDR_W5bgQzkmKMoZjM_a8ph49tg5Fg61KyFo0R-WtGREZUIGESvjfsIyDw=\" rel=\"nofollow\" target=\"_blank\">dan@1abmedia.com<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgwNjAyNyM3NzYzNDMzIzIyNTkyMjc=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" 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(Nasdaq: APGE), a clinical-stage biotechnology company advancing optimized, novel biologics with the potential for best-in-class profiles in the largest inflammatory and immunology (I&amp;I) markets, today reported second quarter 2026 financial results, recent corporate updates and pipeline progress. &#8220;The second quarter marked a transformational period for Apogee,&#8221; said Michael Henderson, M.D., Chief Executive Officer of &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Apogee Reports Second Quarter 2026 Financial Results and Recent Corporate and Pipeline Updates&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-992569","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Apogee Reports Second Quarter 2026 Financial Results and Recent Corporate and Pipeline Updates - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Apogee Reports Second Quarter 2026 Financial Results and Recent Corporate and Pipeline Updates - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"AbbVie to acquire Apogee for $135.11 per share in cash for total equity value of approximately $10.9 billion, positioning differentiated immunology portfolio to reach more patients worldwide Positive 16-week Phase 2 APEX Part B induction dose optimization results support planned advancement of zumilokibart into Phase 3 development in moderate-to-severe atopic dermatitis this year SAN FRANCISCO and BOSTON, Aug. 10, 2026 (GLOBE NEWSWIRE) &#8212; Apogee Therapeutics, Inc. (Nasdaq: APGE), a clinical-stage biotechnology company advancing optimized, novel biologics with the potential for best-in-class profiles in the largest inflammatory and immunology (I&amp;I) markets, today reported second quarter 2026 financial results, recent corporate updates and pipeline progress. &#8220;The second quarter marked a transformational period for Apogee,&#8221; said Michael Henderson, M.D., Chief Executive Officer of &hellip; Continue reading &quot;Apogee Reports Second Quarter 2026 Financial Results and Recent Corporate and Pipeline Updates&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-08-10T11:06:08+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgwNjAyNyM3NzYzNDMzIzIyNTkyMjc=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"15 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Apogee Reports Second Quarter 2026 Financial Results and Recent Corporate and Pipeline Updates\",\"datePublished\":\"2026-08-10T11:06:08+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\\\/\"},\"wordCount\":2991,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTgwNjAyNyM3NzYzNDMzIzIyNTkyMjc=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/apogee-reports-second-quarter-2026-financial-results-and-recent-corporate-and-pipeline-updates\\\/\",\"name\":\"Apogee Reports Second Quarter 2026 Financial Results and Recent Corporate and Pipeline Updates - 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