{"id":990538,"date":"2026-08-05T19:09:38","date_gmt":"2026-08-05T23:09:38","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/"},"modified":"2026-08-05T19:09:38","modified_gmt":"2026-08-05T23:09:38","slug":"akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/","title":{"rendered":"Akebia Therapeutics Reports Second Quarter 2026 Financial Results and Business Highlights"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"center\">\n        <em>Q2 2026 Vafseo<sup>\u00ae<\/sup> (vadadustat) net product revenues grew to\u00a0<\/em><br \/>\n        <em>$21.3 million<\/em><br \/>\n        <em>; more than<\/em><br \/>\n        <em> 10,500 p<\/em><br \/>\n        <em>atients now on therapy<\/em>\n      <\/p>\n<p align=\"center\">\n        <em>Advancement of rare kidney disease pipeline continues with initiation of Phase 2 open-label basket trial evaluating ebribafusp for treatment of IgA nephropathy, lupus nephritis and C3 glomerulopathy; <\/em><br \/>\n        <em>initial data expected in 2027<\/em>\n      <\/p>\n<p align=\"center\">\n        <em>Interim analysis of VOICE trial demonstrated overwhelming statistical evidence of improved safety outcomes for patients treated with Vafseo versus an ESA <\/em>\n      <\/p>\n<p align=\"center\">\n        <em>Akebia to host conference call at 4:30 p.m. EDT on August 5, 2026 <\/em>\n      <\/p>\n<p>CAMBRIDGE, Mass., Aug.  05, 2026  (GLOBE NEWSWIRE) &#8212; <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=BxifM6IGdSBvDqPmyP4XDsoTEOhDlLnEfUNMbMARa7_ZqqS7s40RIexD5VfZBxYSklyJKGv64Y4QjmMAsvsZvskrmruHJ9Fh5q8ZY6iddTY=\" rel=\"nofollow\" target=\"_blank\">Akebia Therapeutics<sup>\u00ae<\/sup>, Inc.<\/a> (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today reported financial results for the second quarter ended June 30, 2026 and shared recent business highlights related to the commercial launch of Vafseo<sup>\u00ae<\/sup> (vadadustat) and its advancing rare kidney disease pipeline.<\/p>\n<p align=\"justify\">\u201cWe\u2019re pleased with Vafseo\u2019s continued sequential revenue growth this quarter, as well as the recently announced positive VOICE trial results for the primary endpoint, which marks an important step in our ultimate goal of making Vafseo standard of care for the treatment of anemia in patients on dialysis,\u201d said John P. Butler, Chief Executive Officer of Akebia. \u201cWe also continue to make strong progress advancing our rare kidney disease pipeline with the initiation of our Phase 2 basket trial evaluating ebribafusp for the treatment of three rare glomerular kidney diseases, with initial data expected in 2027. Further, enrollment continues in our Phase 2 trial of praliciguat in FSGS.\u201d<\/p>\n<p>\n        <strong>Second Quarter and Recent Business Highlights:<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:3pt;margin-bottom:3pt\">Vafseo net product revenues grew to $21.3 million in Q2, representing a 34% increase over Q1 of this year. More than 10,500 patients were active on Vafseo in Q2, representing a 41% increase from the end of Q1 2026. Total number of prescribers increased to approximately 1,200, representing an increase of approximately 17% versus Q1 2026.<\/li>\n<li>In August, <a href=\"https:\/\/ir.akebia.com\/news-releases\/news-release-details\/akebia-therapeutics-announces-initiation-phase-2-basket-trial\" rel=\"nofollow\" target=\"_blank\">Akebia announced that it initiated a Phase 2 open-label basket trial of ebribafusp (previously known as AKB-097 and ADX-097), a next-generation complement inhibitor.<\/a> The trial of ebribafusp in patients with IgA nephropathy, lupus nephritis or C3 glomerulopathy is expected to enroll up to 30 patients dosed subcutaneously once weekly. As part of this study, Akebia will measure urine protein creatinine ratio (UPCR), kidney function measured by estimated glomerular filtration rate (eGFR), and ebribafusp pharmacokinetics. In addition, the trial will measure blood and urine complement biomarkers to determine if ebribafusp reduces complement activity in kidneys while avoiding complement system inhibition in the blood. The Phase 2 basket trial is open-label, and Akebia expects to report initial data in 2027.<\/li>\n<li style=\"margin-top:3pt;margin-bottom:3pt\">In June, <a href=\"https:\/\/ir.akebia.com\/news-releases\/news-release-details\/us-renal-care-and-akebia-announce-interim-analysis-voice-trial\" rel=\"nofollow\" target=\"_blank\">U.S. Renal Care (USRC) and Akebia announced that a planned interim analysis of the VOICE trial (n=2,116) met its predefined stopping criteria.<\/a> The data showed a statistically significant improved safety outcome in patients treated with Vafseo dosed three times per week (TIW) versus erythropoiesis stimulating agents (ESA) on the hierarchical composite endpoint of all-cause mortality and hospitalization (win odds 1.16; 95% CI 1.06, 1.28; p=0.0016), driven by a significant reduction in hospitalizations. The trial results replicated the safety outcomes from the post-hoc win statistics analysis of the Phase 3 INNO<sub>2<\/sub>VATE clinical trial. USRC expects to submit the data for presentation at an upcoming medical meeting.<\/li>\n<li style=\"margin-top:3pt;margin-bottom:3pt\">In June, <a href=\"https:\/\/ir.akebia.com\/news-releases\/news-release-details\/akebia-therapeutics-strengthens-vafseor-vadadustat-patent\" rel=\"nofollow\" target=\"_blank\">Akebia announced it had strengthened its Vafseo intellectual property portfolio<\/a> with a new Orange Book\u2013listed patent (U.S. Patent No. 12,569,474, expiring June 2034) and eligibility for a five-year patent term extension on a composition of matter patent, which would extend that patent&#8217;s term to mid-2032. Akebia&#8217;s Vafseo portfolio now includes 14 Orange Book\u2013listed patents, with expiration dates out to 2036.<\/li>\n<li style=\"margin-top:3pt;margin-bottom:3pt\">In May, <a href=\"https:\/\/ir.akebia.com\/news-releases\/news-release-details\/akebia-therapeutics-announces-vadadustat-post-hoc-win-statistics\" rel=\"nofollow\" target=\"_blank\">Akebia announced the publication of a post-hoc win statistics analysis of all-cause mortality and hospitalization from its global Phase 3 INNO<sub>2<\/sub>VATE program<\/a> in the Journal of the American Society of Nephrology, which demonstrated a statistically significant improvement relative to the ESA, darbepoetin alfa, on a hierarchical composite endpoint of all-cause mortality and hospitalization in patients with anemia due to chronic kidney disease receiving dialysis.<\/li>\n<li style=\"margin-top:3pt;margin-bottom:3pt\">In April, <a href=\"https:\/\/ir.akebia.com\/news-releases\/news-release-details\/akebia-therapeutics-appoints-biopharmaceutical-leader-philip\" rel=\"nofollow\" target=\"_blank\">Akebia appointed Philip J. Vickers, Ph.D. to its Board of Directors<\/a>. Dr. Vickers is the President and Chief Executive Officer and a member of the Board of Directors of Solu Therapeutics. He brings deep expertise spanning research and development, translational science and corporate strategy across a broad range of therapeutic areas to the Board.\n<\/li>\n<\/ul>\n<p>\n        <strong>Financial Results <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:3pt;margin-bottom:3pt\">\n          <strong>Revenues:<\/strong> Total revenues were $49.1 million in the second quarter of 2026 compared to $62.5 million in the second quarter of 2025. This decrease was due to a decrease in Auryxia<sup>\u00ae<\/sup> (ferric citrate) revenues which was partially offset by higher Vafseo revenues.      <\/p>\n<ul type=\"square\">\n<li style=\"margin-top:3pt;margin-bottom:3pt\">Vafseo net product revenues were $21.3 million in the second quarter of 2026 compared to $13.3 million in the second quarter of 2025.<\/li>\n<li>Auryxia net product revenues were $25.5 million in the second quarter of 2026 compared to $47.2 million in the second quarter of 2025. We continue to expect Auryxia revenues to decrease in 2026 as compared to 2025 due to generic competition and pricing pressure.<\/li>\n<li style=\"margin-top:3pt;margin-bottom:3pt\">License, collaboration and other revenues were $2.4 million in the second quarter of 2026 compared to $2.0 million in the second quarter of 2025.<\/li>\n<\/ul>\n<\/li>\n<li style=\"margin-top:3pt;margin-bottom:3pt\">\n          <strong>Cost of Goods Sold (COGS):<\/strong> Cost of goods sold was $10.4 million in the second quarter of 2026 compared to $9.9 million in the second quarter of 2025. Of note, Vafseo-related COGS in both periods was derived from pre-launch inventory, which does not include the full cost of manufacturing as a portion of those inventory-related expenses were recorded as research and development expenses in the period incurred prior to Vafseo\u2019s approval in the U.S.<\/li>\n<li style=\"margin-top:3pt;margin-bottom:3pt\">\n          <strong>Research &amp; Development Expenses: <\/strong>Research and development expenses were $14.1 million in the second quarter of 2026 compared to $11.0 million in the second quarter of 2025. The increase in expenses was driven by increased clinical trial activities related to our mid-stage pipeline assets, which include praliciguat and ebribafusp, as well as higher headcount-related costs.<\/li>\n<li style=\"margin-top:3pt;margin-bottom:3pt\">\n          <strong>SG&amp;A Expenses:<\/strong> Selling, general and administrative expenses were $28.2 million in the second quarter of 2026 compared to $26.6 million in the second quarter of 2025. This increase was driven by higher commercialization-related activities.<\/li>\n<li style=\"margin-top:3pt;margin-bottom:3pt\">\n          <strong>Net Income (Loss): <\/strong>Net loss was $8.9 million in the second quarter of 2026 compared to net income of $0.2 million in the second quarter of 2025. The change to a net loss in the second quarter of 2026 resulted from lower revenues and higher expenses during the quarter, including a $1.9 million restructuring expense related to the reorganization of our commercial organization aimed at increasing the efficiency and effectiveness of our commercial efforts.<\/li>\n<li>\n          <strong>Cash Position: <\/strong>Cash and cash equivalents as of June 30, 2026 were approximately $155.5 million as compared to $162.6 million as of March 31, 2026. We believe our existing cash resources and the cash we expect to generate from product, royalty, supply and license revenues, along with our plan to refinance our senior secured term loan facility, will enable us to fund our current operating plan for at least two years. <\/p>\n<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Conference Call<\/strong>\n      <\/p>\n<p>Akebia will host a conference call on Wednesday, August 5, 2026 at 4:30 p.m. EDT to discuss second quarter 2026 earnings. To access the call, please dial (646) 307-1963 or toll-free (800) 715-9871 and enter passcode: 4727037. To avoid delays and ensure timely connection, we encourage dialing into the conference call 15 minutes ahead of the scheduled start time.<\/p>\n<p align=\"justify\">A live webcast of the conference call will be available via the \u201cInvestors\u201d section of Akebia&#8217;s website at: <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=giXa47YGbD8s3KpJO9jauFFi3Su7EKFuBlNTszM0e9RwVFvP8zK5JYNL86qw3fvUOSIZDpE0JBvHqGR6dSIugwO0fdQ-euzOWEt4NhYaCgk=\" rel=\"nofollow\" target=\"_blank\">https:\/\/ir.akebia.com\/<\/a>. An online archive of the webcast can be accessed via the Investors section of Akebia&#8217;s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=giXa47YGbD8s3KpJO9jauFFi3Su7EKFuBlNTszM0e9TPR8bdrDFn79fK15S7-o3fiGgC7FrrAtOuSELMoh5T405DWKPp-_t3XRgdCjZn8yg=\" rel=\"nofollow\" target=\"_blank\">https:\/\/ir.akebia.com<\/a> approximately two hours after the event.<\/p>\n<p align=\"justify\">\n        <strong>About Akebia Therapeutics<\/strong>\n      <\/p>\n<p align=\"justify\">Akebia Therapeutics, Inc. is a fully integrated biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease. Akebia was founded in 2007 and is headquartered in Cambridge, Massachusetts. For more information, please visit our website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=0sxXk1zlbjkJ8OrGNmESavGZYUyK26WVCg0xD_mkKvNxiWx33_h623Y07m6H4dwrBC-IhAQ_mrX9niOO_1PIDw==\" rel=\"nofollow\" target=\"_blank\">www.akebia.com<\/a>, which does not form a part of this release.<\/p>\n<p align=\"justify\">\n        <strong>About Vafseo<sup>\u00ae<\/sup> (vadadustat) tablets <\/strong>\n      <\/p>\n<p align=\"justify\">Vafseo<sup>\u00ae<\/sup> (vadadustat) tablets is a once-daily oral hypoxia-inducible factor prolyl hydroxylase inhibitor that activates the physiologic response to hypoxia to stimulate endogenous production of erythropoietin, increasing hemoglobin and red blood cell production to manage anemia. Vafseo is approved for use in 37 countries.<\/p>\n<p>\n        <strong>INDICATION<\/strong>\n      <\/p>\n<p>VAFSEO is indicated for the treatment of anemia due to chronic kidney disease (CKD) in adults who have been receiving dialysis for at least three months.<\/p>\n<p>\n        <u>Limitations of Use<\/u>\n      <\/p>\n<ul type=\"disc\">\n<li>VAFSEO has not been shown to improve quality of life, fatigue, or patient well-being.<\/li>\n<li>VAFSEO is not indicated for use:\n<ul type=\"disc\">\n<li>As a substitute for red blood cell transfusions in patients who require immediate correction of anemia.<\/li>\n<li>In patients with anemia due to CKD not on dialysis.\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>\n        <strong>IMPORTANT SAFETY INFORMATION about VAFSEO (vadadustat) tablets<\/strong>\n      <\/p>\n<p align=\"center\">\n        <strong>WARNING: INCREASED RISK OF DEATH, MYOCARDIAL INFARCTION, STROKE, VENOUS THROMBOEMBOLISM, and THROMBOSIS OF VASCULAR ACCESS.<\/strong>\n      <\/p>\n<p>\n        <strong>VAFSEO increases the risk of thrombotic vascular events, including major adverse cardiovascular events (MACE). <\/strong>\n      <\/p>\n<p>\n        <strong>Targeting a hemoglobin level greater than 11 g\/dL is expected to further increase the risk of death and arterial and venous thrombotic events, as occurs with erythropoietin stimulating agents (ESAs), which also increase erythropoietin levels. <\/strong>\n      <\/p>\n<p>\n        <strong>No trial has identified a hemoglobin target level, dose of VAFSEO, or dosing strategy that does not increase these risks. <\/strong>\n      <\/p>\n<p>\n        <strong>Use the lowest dose of VAFSEO sufficient to reduce the need for red blood cell transfusions. <\/strong>\n      <\/p>\n<p>\n        <strong>CONTRAINDICATIONS <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li>Known hypersensitivity to VAFSEO or any of its components<\/li>\n<li>Uncontrolled hypertension\n<\/li>\n<\/ul>\n<p>\n        <strong>WARNINGS AND PRECAUTIONS <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li>\n          <strong>Increased Risk of Death, Myocardial Infarction (MI), Stroke, Venous Thromboembolism, and Thrombosis of Vascular Access<\/strong><br \/>\n          <br \/>A rise in hemoglobin (Hb) levels greater than 1 g\/dL over 2 weeks can increase these risks. Avoid\u00a0in patients with a history of MI, cerebrovascular event, or acute coronary syndrome within the 3\u00a0months prior to starting VAFSEO. Targeting a Hb level of greater than 11 g\/dL is expected to\u00a0further increase the risk of death and arterial and venous thrombotic events. Use the lowest\u00a0effective dose to reduce the need for red blood cell (RBC) transfusions. Adhere to dosing and Hb\u00a0monitoring recommendations to avoid excessive erythropoiesis.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\n          <strong>Hepatotoxicity<\/strong><br \/>\n          <br \/>Hepatocellular injury attributed to VAFSEO was reported in less than 1% of patients, including\u00a0one severe case with jaundice. Elevated serum ALT, AST, and bilirubin levels were observed\u00a0in 1.8%, 1.8%, and 0.3% of CKD patients treated with VAFSEO, respectively. Measure ALT,\u00a0AST, and bilirubin before treatment and monthly for the first 6 months, then as clinically\u00a0indicated. Discontinue VAFSEO if ALT or AST is persistently elevated or accompanied by elevated\u00a0bilirubin. Not recommended in patients with cirrhosis or active, acute liver disease.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\n          <strong>Hypertension<\/strong><br \/>\n          <br \/>Worsening of hypertension was reported in 14% of VAFSEO and 17% of darbepoetin alfa\u00a0patients. Serious worsening of hypertension was reported in 2.7% of VAFSEO and 3% of\u00a0darbepoetin alfa patients. Cases of hypertensive crisis, including hypertensive encephalopathy\u00a0and seizures, have also been reported in patients receiving VAFSEO. Monitor blood pressure. Adjust anti-hypertensive therapy as needed.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\n          <strong>Seizures<\/strong><br \/>\n          <br \/>Seizures occurred in 1.6% of VAFSEO and 1.6% of darbepoetin alfa patients. Monitor for new-\u00a0onset seizures, premonitory symptoms, or change in seizure frequency.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\n          <strong>Gastrointestinal (GI) Erosion<\/strong><br \/>\n          <br \/>Gastric or esophageal erosions occurred in 6.4% of VAFSEO and 5.3% of darbepoetin alfa\u00a0patients. Serious GI erosions, including GI bleeding and the need for RBC transfusions, were\u00a0reported in 3.4% of VAFSEO and 3.3% of darbepoetin alfa patients. Consider this risk in patients\u00a0at increased risk of GI erosion. Advise patients about signs of erosions and GI bleeding and urge\u00a0them to seek prompt medical care if present.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\n          <strong>Serious Adverse Reactions in Patients with Anemia Due to CKD and Not on Dialysis <\/strong><br \/>\n          <br \/>The safety of VAFSEO has not been established for the treatment of anemia due to CKD in adults\u00a0not on dialysis and its use is not recommended in this setting. In large clinical trials in adults with\u00a0anemia of CKD who were not on dialysis, an increased risk of mortality, stroke, MI, serious acute\u00a0kidney injury, serious hepatic injury, and serious GI erosions was observed in patients treated\u00a0with VAFSEO compared to darbepoetin alfa.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>\n          <strong>Malignancy<\/strong><br \/>\n          <br \/>VAFSEO has not been studied and is not recommended in patients with active malignancies.\u00a0Malignancies were observed in 2.2% of VAFSEO and 3.0% of darbepoetin alfa patients. No\u00a0evidence of increased carcinogenicity was observed in animal studies.<\/p>\n<\/li>\n<\/ul>\n<p>\n        <strong>ADVERSE REACTIONS <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li>The most common adverse reactions (occurring at \u2265 10%) were hypertension and diarrhea.\n<\/li>\n<\/ul>\n<p>\n        <strong>DRUG INTERACTIONS<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li>\n          <strong>Iron supplements and iron-containing phosphate binders:<\/strong> Administer VAFSEO at least 1 hour before products containing iron.<\/li>\n<li>\n          <strong>Non-iron-containing phosphate binders<\/strong>: Administer VAFSEO at least 1 hour before or 2 hours after non-iron-containing phosphate binders.<\/li>\n<li>\n          <strong>BCRP substrates<\/strong>: Monitor for signs of substrate adverse reactions and consider dose reduction.<\/li>\n<li>\n          <strong>Statins<\/strong>: Monitor for statin-related adverse reactions. Limit the daily dose of simvastatin to 20 mg and rosuvastatin to 5 mg.<\/p>\n<\/li>\n<\/ul>\n<p>\n        <strong>USE IN SPECIFIC POPULATIONS<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li>Pregnancy: May cause fetal harm. A pregnancy exposure registry is available to monitor outcomes in women exposed to VAFSEO during pregnancy. Report pregnancies to 1-844-445-3799.<\/li>\n<li>Lactation: Breastfeeding not recommended until two days after the final dose.<\/li>\n<li>Hepatic Impairment<strong>:<\/strong> Not recommended in patients with cirrhosis or active, acute liver disease.\n<\/li>\n<\/ul>\n<p>\n        <strong>Please note that this information is not comprehensive. Please click <\/strong><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=HzWNuONFdjsEc_5BctrvJggoPrHJiuoC0x8y7ZqbwZ79Sshbfwyh2hm3GD0DB-U6J9UD1ZZreH5WCrl8fMAqrzw5wwOaozsDR9EazUfApEwbEw1ZPmmBFIxpcSp6uB1u\" rel=\"nofollow\" target=\"_blank\"><br \/>\n          <strong>here<\/strong><br \/>\n        <\/a><br \/>\n        <strong> for the Full Prescribing Information, including BOXED WARNING and Medication Guide. <\/strong>\n      <\/p>\n<p align=\"justify\">\n        <strong>Forward-Looking Statements<\/strong>\n      <\/p>\n<p align=\"justify\">Statements in this press release regarding Akebia Therapeutics, Inc.&#8217;s (&#8220;Akebia&#8217;s&#8221;) strategy, plans, prospects, expectations, beliefs, intentions and goals are forward-looking statements within the meaning of the U.S. Private Securities Litigation Reform Act of 1995, as amended, and include, but are not limited to: statements regarding: Akebia&#8217;s plans, strategies and prospects for its business; Akebia\u2019s beliefs regarding Vafseo\u2019s continued revenue growth; Akebia\u2019s beliefs regarding the data and results from the VOICE trial, including that the data demonstrated overwhelming statistical evidence of improved safety outcomes for patients treated with Vafseo versus an ESA; Akebia\u2019s goal of making Vafseo standard of care for the treatment of anemia in patients on dialysis; Akebia\u2019s plans and expectations regarding the Phase 2 open-label basket trial evaluating ebribafusp, including the timing of reporting initial data, the expected number of patients to be enrolled and the timing thereof; Akebia\u2019s beliefs and expectations regarding the progress of its rare kidney disease pipeline, including its Phase 2 trial of praliciguat in FSGS; Akebia and USRC\u2019s plans and expectations regarding submitting data from the VOICE trial for presentation at an upcoming medical meeting; Akebia\u2019s expectations and beliefs about the strength of its Vafseo (vadadustat) intellectual property portfolio and expectations regarding its ability to maintain its intellectual property protection through the respective expiration dates; Akebia\u2019s expectations regarding Auryxia revenues continuing to decrease due to generic competition and pricing pressure; Akebia\u2019s goals and expectations regarding its commercial reorganization aimed at increasing the efficiency and effectiveness of its commercial efforts; Akebia\u2019s beliefs and expectations regarding the cash it expects to generate from product, royalty, supply and license revenues and the sufficiency of, and the period in which Akebia expects to have, cash to fund its current operating plan; and Akebia\u2019s plans to refinance its senior secured term loan facility.<\/p>\n<p align=\"justify\">The terms &#8220;intend,&#8221; &#8220;believe,&#8221; &#8220;plan,&#8221; &#8220;goal,&#8221; &#8220;potential,&#8221; &#8220;anticipate,\u201d &#8220;estimate,&#8221; \u201ctarget,\u201d \u201cpredict,\u201d &#8220;expect,&#8221; &#8220;future,&#8221; \u201cmay,\u201d &#8220;will,&#8221; \u201ccould,\u201d &#8220;continue,&#8221; derivatives of these words, and similar references are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results, performance or experience may differ materially from those expressed or implied by any forward-looking statement as a result of various risks, uncertainties and other factors, including, but not limited to, risks associated with:<\/p>\n<p align=\"justify\">the potential therapeutic benefits, safety profile, and effectiveness of Akebia\u2019s products and product candidates; risks and uncertainties related to Akebia\u2019s ongoing and planned research and development activities, including initiating, conducting or completing preclinical studies and clinical trials, and the timing of such preclinical studies and clinical trials; the results of Akebia\u2019s preclinical studies and clinical trials, including that initial, preliminary, interim or retrospective data, analysis or results may not be replicated in, or predictive of, final analyses or results of future preclinical or clinical data, analyses or results or that such analysis or results may not support further development of such product candidates; Akebia\u2019s ability to initiate and enroll patients in its clinical trials; decisions made by health authorities, such as the FDA, with respect to regulatory filings and other interactions; the potential demand and market potential and acceptance of, as well as coverage and reimbursement related to Akebia\u2019s commercial products, including estimates regarding the potential market opportunity; the competitive landscape for Akebia\u2019s commercial products, including generic entrants and the timing thereof; Akebia\u2019s ability to obtain and maintain patent protection on its products and product candidates, and to successfully defend these patents against third-party challenges; Akebia\u2019s ability to attract and retain qualified personnel; Akebia&#8217;s ability to achieve and maintain profitability and to maintain operating expenses consistent with its operating plan; Akebia\u2019s revenue and that its financial results from prior periods may not be indicative of future results; manufacturing, supply chain and quality matters and any recalls, write-downs, impairments or other related consequences or potential consequences; early termination of any of Akebia&#8217;s collaborations; and changes in the geopolitical environment and uncertainty surrounding U.S. trade policy on tariffs. Other risks and uncertainties include those identified under the heading &#8220;Risk Factors&#8221; in Akebia&#8217;s most recent Quarterly Report on Form 10-Q filed with the U.S. Securities and Exchange Commission (SEC), and other filings that Akebia may make with the SEC in the future. These forward-looking statements (except as otherwise noted) speak only as of the date of this press release, and, except as required by law, Akebia does not undertake, and specifically disclaims, any obligation to update any forward-looking statements contained in this press release.<\/p>\n<p align=\"justify\">Akebia Therapeutics<sup>\u00ae<\/sup>, Auryxia<sup>\u00ae<\/sup> and Vafseo<sup>\u00ae<\/sup> are registered trademarks of Akebia Therapeutics, Inc. and its affiliates.<\/p>\n<p align=\"justify\">\n        <strong>Akebia Therapeutics Contact<br \/><\/strong>Mercedes Carrasco<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=0yw8Xzbc2nMKOYyyBlhS9kzCsSOKG46-a-r3985VnHITl55FN08UUK9E4I4nH92MLYAtZslO8B3aoITUh0tdP0QLROWAIOtSJNxiW2XTS18=\" rel=\"nofollow\" target=\"_blank\">mcarrasco@akebia.com<\/a>\u00a0<\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td colspan=\"8\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>AKEBIA THERAPEUTICS, INC.<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"8\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Unaudited Condensed Consolidated Statements of Operations<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"8\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"7\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Three Months Ended June 30,<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\n            <strong>(in thousands, except per share data)<\/strong>\n          <\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2026<\/strong><br \/>\n            \n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2025<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td style=\"border-top: solid black 1pt;vertical-align: middle\">\n            <strong>Revenues<\/strong>\n          <\/td>\n<td colspan=\"3\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:67%;width:67%;min-width:67%;vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">Product revenue, net<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">$<\/td>\n<td style=\"max-width:14%;width:14%;min-width:14%;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">46,765<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">$<\/td>\n<td style=\"max-width:14%;width:14%;min-width:14%;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">60,461<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">License, collaboration and other revenue<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">2,363<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">2,011<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">\u00a0 \u00a0Total revenues<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">49,128<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">62,472<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\n            <strong>Cost of goods sold<\/strong>\n          <\/td>\n<td colspan=\"3\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">Cost of product and other revenue<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">10,424<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">9,919<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">\u00a0 \u00a0Total cost of goods sold<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">10,424<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">9,919<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\n            <strong>Operating expenses<\/strong>\n          <\/td>\n<td colspan=\"3\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">Research and development<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">14,059<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">11,013<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">Selling, general and administrative<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">28,171<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">26,555<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">License<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">855<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">896<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">Restructuring<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">1,945<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u2014<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: middle\">\u00a0 \u00a0Total operating expenses<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">45,030<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">38,464<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\n            <strong>Income (loss) from operations<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\n            <strong>(6,326<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\n            <strong>14,089<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">Other expense, net<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">(3,078<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">(6,862<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">Change in fair value of warrant liability<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">566<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">(6,980<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\n            <strong>Income (loss) before income taxes<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\n            <strong>(8,838<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">\n            <strong>247<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: middle\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">Income tax expense<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">(70<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\u2014<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\n            <strong>Net income (loss)<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double black 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">$<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double black 3pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">(8,908<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double black 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double black 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">$<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double black 3pt;padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">247<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double black 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-top: double black 3pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-top: double black 3pt;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">Net income (loss) per share &#8211; basic<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">$<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(0.03<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">$<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">0.00<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">Net income (loss) per share &#8211; diluted<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">$<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(0.03<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">$<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">0.00<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">Weighted-average number of common shares &#8211; basic<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">269,602,747<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">262,565,500<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">Weighted-average number of common shares &#8211; diluted<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">269,602,747<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-left: 0;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">271,104,020<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<\/table>\n<p>\n        \n      <\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td colspan=\"6\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Unaudited Selected Balance Sheet Data<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"6\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\n            <strong>(in thousands)<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>June 30, 2026<\/strong>\n          <\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>December 31, 2025<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:69%;width:69%;min-width:69%;border-top: solid black 1pt;vertical-align: bottom\">Cash and cash equivalents<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">$<\/td>\n<td style=\"max-width:14%;width:14%;min-width:14%;border-top: solid black 1pt;padding-left: 0;text-align: right;vertical-align: middle;vertical-align: middle\">155,548<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">$<\/td>\n<td style=\"max-width:14%;width:14%;min-width:14%;border-top: solid black 1pt;padding-left: 0;text-align: right;vertical-align: middle;vertical-align: middle\">184,844<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Working capital<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">$<\/td>\n<td style=\"padding-left: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">68,688<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">$<\/td>\n<td style=\"padding-left: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">90,017<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Total assets<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">$<\/td>\n<td style=\"padding-left: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">349,658<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">$<\/td>\n<td style=\"padding-left: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">376,565<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Total stockholders\u2019 equity<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: middle\">$<\/td>\n<td style=\"padding-left: 0;text-align: right;vertical-align: middle;vertical-align: middle\">25,018<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">$<\/td>\n<td style=\"padding-left: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">32,610<\/td>\n<\/tr>\n<\/table>\n<p>\n        \n      <\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgwNDI5OSM3NzYwNTMzIzIwMDYzNTU=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/M2MyNjI1ZDMtYzgxYi00OGI1LTg3ODEtOGU1N2I4OTM3NTE5LTEwMTc5MjgtMjAyNi0wOC0wNS1lbg==\/tiny\/Akebia-Therapeutics-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Q2 2026 Vafseo\u00ae (vadadustat) net product revenues grew to\u00a0 $21.3 million ; more than 10,500 p atients now on therapy Advancement of rare kidney disease pipeline continues with initiation of Phase 2 open-label basket trial evaluating ebribafusp for treatment of IgA nephropathy, lupus nephritis and C3 glomerulopathy; initial data expected in 2027 Interim analysis of VOICE trial demonstrated overwhelming statistical evidence of improved safety outcomes for patients treated with Vafseo versus an ESA Akebia to host conference call at 4:30 p.m. EDT on August 5, 2026 CAMBRIDGE, Mass., Aug. 05, 2026 (GLOBE NEWSWIRE) &#8212; Akebia Therapeutics\u00ae, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today reported financial results for &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Akebia Therapeutics Reports Second Quarter 2026 Financial Results and Business Highlights&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-990538","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Akebia Therapeutics Reports Second Quarter 2026 Financial Results and Business Highlights - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Akebia Therapeutics Reports Second Quarter 2026 Financial Results and Business Highlights - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Q2 2026 Vafseo\u00ae (vadadustat) net product revenues grew to\u00a0 $21.3 million ; more than 10,500 p atients now on therapy Advancement of rare kidney disease pipeline continues with initiation of Phase 2 open-label basket trial evaluating ebribafusp for treatment of IgA nephropathy, lupus nephritis and C3 glomerulopathy; initial data expected in 2027 Interim analysis of VOICE trial demonstrated overwhelming statistical evidence of improved safety outcomes for patients treated with Vafseo versus an ESA Akebia to host conference call at 4:30 p.m. EDT on August 5, 2026 CAMBRIDGE, Mass., Aug. 05, 2026 (GLOBE NEWSWIRE) &#8212; Akebia Therapeutics\u00ae, Inc. 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(Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today reported financial results for &hellip; Continue reading \"Akebia Therapeutics Reports Second Quarter 2026 Financial Results and Business Highlights\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/","og_site_name":"Market Newsdesk","article_published_time":"2026-08-05T23:09:38+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgwNDI5OSM3NzYwNTMzIzIwMDYzNTU=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"15 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Akebia Therapeutics Reports Second Quarter 2026 Financial Results and Business Highlights","datePublished":"2026-08-05T23:09:38+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/"},"wordCount":3028,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgwNDI5OSM3NzYwNTMzIzIwMDYzNTU=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/akebia-therapeutics-reports-second-quarter-2026-financial-results-and-business-highlights\/","name":"Akebia Therapeutics Reports Second Quarter 2026 Financial Results and Business Highlights - 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