{"id":987139,"date":"2026-07-30T07:28:03","date_gmt":"2026-07-30T11:28:03","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/alterity-therapeutics-releases-appendix-4c-q4-fy26-quarterly-cash-flow-report-corporate-update\/"},"modified":"2026-07-30T07:28:03","modified_gmt":"2026-07-30T11:28:03","slug":"alterity-therapeutics-releases-appendix-4c-q4-fy26-quarterly-cash-flow-report-corporate-update","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/alterity-therapeutics-releases-appendix-4c-q4-fy26-quarterly-cash-flow-report-corporate-update\/","title":{"rendered":"Alterity Therapeutics Releases Appendix 4C \u2013 Q4 FY26 Quarterly Cash Flow Report &amp; Corporate Update"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"justify\">\n        <strong>Highlights<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-bottom:5pt\">FDA End-of-Phase 2 (EOP2) meeting minutes confirmed a registrational pathway for ATH434 in Multiple System Atrophy (MSA)<\/li>\n<li style=\"margin-bottom:5pt\">FDA agreed that a single pivotal Phase 3 trial plus confirmatory evidence could support an approval of ATH434 for the treatment of MSA<\/li>\n<li style=\"margin-bottom:5pt\">Pivotal Phase 3 trial activities on track to initiate by year-end 2026<\/li>\n<li style=\"margin-bottom:5pt\">Continued evaluation of strategic funding and partnering alternatives to support Phase 3 development and maximise long-term shareholder value<\/li>\n<li style=\"margin-bottom:5pt\">Peer-reviewed publication in <em>NeuroImage<\/em> validated quantitative susceptibility mapping (QSM) of iron on MRI as a biomarker of MSA<\/li>\n<li style=\"margin-bottom:5pt\">Strengthened the Board of Directors with the appointment of Ms Ann Cunningham<\/li>\n<li style=\"margin-bottom:5pt\">A$3.98 million Australian R&amp;D Tax Incentive refund received subsequent to quarter end, supporting continued development of Alterity\u2019s clinical programs<\/li>\n<li style=\"margin-bottom:5pt\">Cash balance of A$37.3 million as at 30 June 2026\n<\/li>\n<\/ul>\n<p align=\"justify\">MELBOURNE, Australia and SAN FRANCISCO, July  30, 2026  (GLOBE NEWSWIRE) &#8212; <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=OykTYN1zihOXp4xgSd6670mtHeWKENIxHoViaRaMql4dbgfG8g7sCdhjHNXAyMRwF3H3XVCTAPVAq12fIJvb5tA4Btub7iNJOOy-oVXpfT4=\" rel=\"nofollow\" target=\"_blank\">Alterity Therapeutics<\/a> (ASX: ATH, NASDAQ: ATHE) (\u201cAlterity\u201d or \u201cthe Company\u201d), a biotechnology company dedicated to developing disease modifying treatments for neurodegenerative diseases, today released its Appendix 4C Quarterly Cash Flow Report and update on company activities for the quarter ending 30 June 2026 (Q4 FY26).<\/p>\n<p align=\"justify\">\u201cThis was a defining quarter for Alterity, highlighted by our positive End of Phase 2 meeting with the FDA that established a clear, efficient registrational pathway for ATH434,\u201d said David Stamler, M.D., Chief Executive Officer. \u201cWith the Phase 3 design elements agreed upon, we are executing on our plans to initiate Phase 3 trial activities by year-end 2026.\u201d<\/p>\n<p align=\"justify\">Dr. Stamler continued, \u201cThe regulatory clarity we have now achieved, together with the growing body of clinical evidence supporting ATH434, puts us in a strong position as we prepare to initiate Phase 3 and continue strategic and other funding discussions aimed at maximising the long-term value of the program.\u201d<\/p>\n<p align=\"justify\">\n        <strong>ATH434 Clinical and Regulatory Update<\/strong>\n      <\/p>\n<p align=\"justify\">Alterity achieved several key regulatory milestones during the quarter. The Company reached alignment with the U.S. Food and Drug Administration (FDA) at its End-of-Phase 2 (EOP2) meeting on the registrational pathway for a potential New Drug Application (NDA) for ATH434 in MSA. At the meeting, the FDA indicated that a single pivotal trial plus confirmatory evidence could provide the data necessary to support approval, with the Company anticipating that the data from its ATH434-201 Phase 2 clinical trial will provide the required confirmatory evidence. This outcome represents one of the most significant regulatory milestones achieved by the Company to date and de-risks the regulatory pathway toward potential approval of ATH434 in MSA. Successful completion of the planned Phase 3 program has the potential to support the first disease-modifying treatment approved for Multiple System Atrophy, a rare and rapidly progressive neurodegenerative disease with no approved therapy.<\/p>\n<p align=\"justify\">Alignment was reached with the agency on several key elements of the proposed Phase 3 trial design, including the study population, treatment regimen and the use of the 11-item UMSARS Part I rating scale<sup>1<\/sup> as the primary endpoint. Key secondary endpoints that assess key areas of impairment in MSA were agreed upon and the FDA also indicated that the anticipated size of the safety database at the conclusion of the Phase 3 trial was reasonable. The study is expected to enroll approximately 200 patients who will be randomized 1:1 to ATH434 50 mg or matching placebo treatment twice daily for 12 months. Alterity plans to offer an open-label extension to participants who complete the Phase 3 trial, both to continue their treatment and to enhance the safety database for ATH434.<\/p>\n<p align=\"justify\">In April 2026, Alterity announced positive FDA feedback following a Type C meeting related to the chemistry, manufacturing and control (CMC) elements of the Phase 3 program. In preparation for Phase 3, Alterity has successfully manufactured the first registration batch of ATH434 for use in the pivotal trial.<\/p>\n<p>\n        <strong>Scientific Engagement<\/strong>\n      <\/p>\n<p>Alterity continues to actively engage with the global neurology community through multiple scientific presentations at leading international congresses. These presentations formed an important component of the Company\u2019s strategy to disseminate clinical data, engage with key opinion leaders and specialists, and further interpret Phase 2 results for ATH434 in MSA.<\/p>\n<p>During the quarter, Alterity delivered the following presentations, which are available on the <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=-XPdwe2H0gNEZZm4XqZQIlP_-E-prju_4bCbf0ZNozS6UO4mySOyJqOFZPT9sPnlXMdCYek5fcKqHZJtfEwwgf_nt0AM8S4UAL8Y7KtIgVLGRcU3FY6mPbBZ_5-4W5WWfwiypgoGFgikjAJF31b_tg==\" rel=\"nofollow\" target=\"_blank\">Publications and Presentations<\/a> page of the Company\u2019s website:<\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:0.3pt;margin-bottom:4pt\">April 2026 \u2013 American Academy of Neurology (AAN) Annual Meeting, Late-Breaking Science: An analysis using the newly described MSA Combined Outcome Assessment (MuSyCA)<sup>2<\/sup> composite scale, which integrates items from UMSARS Parts I and II, showed ATH434 slowed functional decline versus placebo at Week 52, consistent with previously reported activity on the 11-item UMSARS Part I.<\/li>\n<li style=\"margin-top:0.3pt;margin-bottom:4pt\">May 2026 \u2013 Peer-reviewed publication in <em>NeuroImage<\/em>: A study drawing on the Company\u2019s bioMUSE Natural History Study demonstrated that quantitative susceptibility mapping (QSM) of brain iron detects disease-specific accumulation in MSA, distinguishes MSA from Parkinson\u2019s disease, and correlates with clinical severity in MSA.<\/li>\n<li>May 2026 \u2013 Three international scientific presentations at the International Society for Magnetic Resonance in Medicine (ISMRM), the Movement Disorder Society of Australia and New Zealand (MDSANZ) Scientific Meeting, and the MSA Symposium (University College London), presenting QSM imaging, CSF NfL<sup>3<\/sup> covariate analyses and swallowing outcome data supporting ATH434\u2019s mechanism as an iron chaperone.\n<\/li>\n<\/ul>\n<p align=\"justify\">Also during the period, the Company hosted a <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=BPxp545FoDYcqloSGPAoh6FWzg7zG8Rkuqln8LaJ4_7QMQkSislQjlqf8jYoeoUKSK3HfZGL_05L2QqN0UQmzPKElDJ84WM1WhACeuY4XZWnvP45K0z8kkAFolyTpNEFxPor1owMYwNupqm17o66wXhyO7Newfa4dQ862br0Uxc=\" rel=\"nofollow\" target=\"_blank\">virtual key opinion leader (KOL) event<\/a> featuring Roy Freeman, M.D. (Harvard Medical School) and Daniel Claassen, M.D., M.S. (Vanderbilt University Medical Center), alongside CEO David Stamler, M.D., to discuss the unmet need and treatment landscape in MSA and the ATH434 development program.<\/p>\n<p>\n        <strong>Strategic Partnering and Funding Alternatives<\/strong>\n      <\/p>\n<p align=\"justify\">Alterity continues to evaluate a range of strategic and funding alternatives to support the advancement of ATH434, including ongoing discussions with a number of pharmaceutical companies. The Company is progressing a structured evaluation process, with the assistance of external advisers, to assess these opportunities alongside other potential funding and development pathways.<\/p>\n<p align=\"justify\">The Company remains focused on maintaining strategic flexibility while pursuing the pathway that best supports the advancement of ATH434 and maximises long-term shareholder value.<\/p>\n<p align=\"justify\">\n        <strong>Corporate and Financial Update<\/strong>\n      <\/p>\n<p align=\"justify\">\n        <u>Governance and Leadership<\/u>\n      <\/p>\n<p align=\"justify\">In April 2026, the company announced the appointment of Ms Ann Cunningham to the Board of Directors as an independent Non-Executive Director. Ms Cunningham\u2019s appointment adds global commercial and strategic expertise as the company transitions toward late-stage development in MSA.<\/p>\n<p>\n        <u>Share Consolidation<\/u>\n      <\/p>\n<p>Following shareholder approval at the Extraordinary General Meeting held on 29 May 2026, the Company completed a consolidation of its share capital on a 1-for-50 basis.<\/p>\n<p align=\"justify\">\n        <u>Cash Position<\/u>\n      <\/p>\n<p align=\"justify\">As of 30 June 2026, Alterity held cash and cash equivalents of A$37.3 million. Operating cash outflows for the quarter were A$7.72 million.<\/p>\n<p align=\"justify\">Subsequent to quarter-end, on 9 July 2026, the Company received its research and development (R&amp;D) tax refund for the 2025 financial year totaling A$3,982,992 (including A$43,117 of interest), under the Australian Government\u2019s R&amp;D Tax Incentive.<\/p>\n<p align=\"justify\">In accordance with ASX Listing Rule 4.7C, payments of A$309k made to related parties and their associates during the quarter included non-executive directors\u2019 fees, managing director salary, consulting fees, remuneration and superannuation at commercial rates.<\/p>\n<p align=\"justify\">The full financial report can be found in the ASX filing\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=yWQozg_Pd_oYMkmVp-54ngXj6LdR8aOSNhRcAqMdrG0rX27518vhXxu8AzGcQ7tSIaX-0tXZTmr6tQQ0J0nowkd1U_WjZ8GeVLoN0h8VwLo=\" rel=\"nofollow\" target=\"_blank\">here<\/a>.<\/p>\n<p align=\"justify\">\n        <strong>About Alterity Therapeutics Limited <\/strong>\n      <\/p>\n<p align=\"justify\">Alterity Therapeutics is a clinical stage biotechnology company dedicated to creating an alternate future for people living\u00a0with neurodegenerative diseases. The Company is focused on developing disease modifying therapies in Multiple System Atrophy (MSA) and related Parkinsonian disorders. Alterity is preparing to initiate a Phase 3 pivotal trial in MSA, a rare and rapidly progressive disease. ATH434, the Company\u2019s lead asset, has demonstrated clinically meaningful efficacy in a randomized, double-blind, placebo-controlled Phase 2 clinical trial in participants with MSA. Alterity has further reported positive data in its open label Phase 2 clinical trial in participants with advanced MSA. In addition, Alterity has a broad drug discovery platform generating patentable chemical compounds to treat the underlying pathology of neurological diseases. The Company is based in Melbourne, Australia, and San Francisco, California, USA. For further information please visit the Company\u2019s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=S7Q_ML1nBnk2S373N3_eJIrG-rLKAa_REWz8g0ctzECm66IE7eSbHSjLsZDwmBJMDAE5EqoCXsTaWBWmBSWxPBwTU0gCKIoMgiZlmbDj668=\" rel=\"nofollow\" target=\"_blank\">https:\/\/alteritytx.com<\/a>.<\/p>\n<p align=\"justify\">\n        <strong>References<\/strong><br \/>\n        <br \/>\n        <sup>1 <\/sup>11-item UMSARS Part I (previously described as modified UMSARS I): Unified Multiple System Atrophy Rating Scale, 11-Items include: Orthostatic symptoms, Swallowing, Speech, Handwriting, Cutting food, Dressing, Hygiene, Walking, Falling, Urinary and Bowel function.<br \/><sup>2<\/sup> For the MuSyCa MSA Combined Outcome assessment: UMSARS I items were swallowing, handwriting, utensils, dressing, hygiene, walking; UMSARS I items were speech, leg agility, arising from chair, body sway, gait <br \/><sup>3 <\/sup>Neurofilament Light Chain\u00a0measured in the\u00a0cerebrospinal fluid (CSF)<\/p>\n<p>\n        <br \/>\n        <strong>Authorisation &amp; Additional information<\/strong><br \/>\n        <br \/>This announcement was authorized by the Board of Directors of Alterity Therapeutics Limited.<\/p>\n<p>\n        <strong>Contacts:<\/strong>\n      <\/p>\n<p>\n        <strong>Investors<\/strong><br \/>\n        <br \/>Elyse Shapiro<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Ja6WuuyMOhtqB0CINwzzlk_adaUSZ7MD7ejZgwwRsxlDz2UYKeXCrOU-u4q0f-jvOikxlQIHIRBc3MWC5yKfGY5d_6FmkdIKkqbfto-DyIs=\" rel=\"nofollow\" target=\"_blank\">ir@alteritytx.com<\/a><\/p>\n<p>Remy Bernarda<br \/>Investor Relations Advisory Solutions<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Ja6WuuyMOhtqB0CINwzzlqHrMg9jSHUrgkhS-zGCKU75RWPFcSu_Copf8m3LQ0Woowqn2ek-ElJ07zDD2FUlpFk6hUPwd3Rr7tB38PpoqsY=\" rel=\"nofollow\" target=\"_blank\">ir@alteritytx.com<\/a><br \/>+1 (415) 203-6386<\/p>\n<p>\n        <strong>Media<\/strong><br \/>\n        <br \/>Melissa Tempra<br \/>NWR Communications<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=x07Vqr3gca4XSjmoncjouDsiD_aqhXEVqSyyRHYsTKydcI75u1fAFMEZFziOnmRS3KMPKdGegARpCg9lo-t717etSujZ9LT8jAEVeyLiYKt8BoH7YnZpYN_r1ZpPSUtQzPmNivSkYpFXewtu4NOM6Q==\" rel=\"nofollow\" target=\"_blank\">melissa@nwrcommunications.com.au<\/a><\/p>\n<p>Casey McDonald<br \/>Tiberend Strategic Advisors, Inc.<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=jmePCtMwF2SqN2Uz8wsS4BQxN-7o-RlBOvqiEQmZcFF3WVgmtYH_06MPEYnaHbH7yh8AtG3ykGD08gYaOZsv20Bpa5Ke2tUf4pCDVloYq0o=\" rel=\"nofollow\" target=\"_blank\">cmcdonald@tiberend.com<\/a><br \/>+1 (646) 577-8520<\/p>\n<p align=\"justify\">\n        <strong>Forward Looking Statements<br \/><\/strong><br \/>\n        <em>This press release contains &#8220;forward-looking statements&#8221; within the meaning of section 27A of the Securities Act of 1933 and section<\/em><br \/>\n        <em>21E<\/em><br \/>\n        <em>of<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>Securities<\/em><br \/>\n        <em>Exchange<\/em><br \/>\n        <em>Act<\/em><br \/>\n        <em>of<\/em><br \/>\n        <em>1934.<\/em><br \/>\n        <em>The<\/em><br \/>\n        <em>Company<\/em><br \/>\n        <em>has<\/em><br \/>\n        <em>tried<\/em><br \/>\n        <em>to<\/em><br \/>\n        <em>identify<\/em><br \/>\n        <em>such<\/em><br \/>\n        <em>forward-looking<\/em><br \/>\n        <em>statements<\/em><br \/>\n        <em>by<\/em><br \/>\n        <em>use of such words as &#8220;expects,&#8221; &#8220;intends,&#8221; &#8220;hopes,&#8221; &#8220;anticipates,&#8221; &#8220;believes,&#8221; &#8220;could,&#8221; &#8220;may,&#8221; &#8220;evidences&#8221; and &#8220;estimates,&#8221; and other similar expressions, but these words are not the exclusive means of identifying such<\/em><br \/>\n        <em>statements.<\/em>\n      <\/p>\n<p align=\"justify\">\n        <em>Important<\/em><br \/>\n        <em>factors<\/em><br \/>\n        <em>that<\/em><br \/>\n        <em>could<\/em><br \/>\n        <em>cause<\/em><br \/>\n        <em>actual<\/em><br \/>\n        <em>results<\/em><br \/>\n        <em>to<\/em><br \/>\n        <em>differ<\/em><br \/>\n        <em>materially<\/em><br \/>\n        <em>from<\/em><br \/>\n        <em>those<\/em><br \/>\n        <em>indicated<\/em><br \/>\n        <em>by<\/em><br \/>\n        <em>such<\/em><br \/>\n        <em>forward-looking<\/em><br \/>\n        <em>statements are<\/em><br \/>\n        <em>described<\/em><br \/>\n        <em>in<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>sections<\/em><br \/>\n        <em>titled<\/em><br \/>\n        <em>\u201cRisk<\/em><br \/>\n        <em>Factors\u201d<\/em><br \/>\n        <em>in<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>Company\u2019s<\/em><br \/>\n        <em>filings<\/em><br \/>\n        <em>with<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>SEC,<\/em><br \/>\n        <em>including<\/em><br \/>\n        <em>its<\/em><br \/>\n        <em>most<\/em><br \/>\n        <em>recent<\/em><br \/>\n        <em>Annual<\/em><br \/>\n        <em>Report on<\/em><br \/>\n        <em>Form<\/em><br \/>\n        <em>20-F<\/em><br \/>\n        <em>as<\/em><br \/>\n        <em>well<\/em><br \/>\n        <em>as<\/em><br \/>\n        <em>reports<\/em><br \/>\n        <em>on<\/em><br \/>\n        <em>Form<\/em><br \/>\n        <em>6-K,<\/em><br \/>\n        <em>including,<\/em><br \/>\n        <em>but<\/em><br \/>\n        <em>not<\/em><br \/>\n        <em>limited<\/em><br \/>\n        <em>to<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>following:<\/em><br \/>\n        <em>statements<\/em><br \/>\n        <em>relating<\/em><br \/>\n        <em>to<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>Company&#8217;s drug development program, including, but not limited to the initiation, progress and outcomes of clinical trials of the Company&#8217;s<\/em><br \/>\n        <em>drug<\/em><br \/>\n        <em>development<\/em><br \/>\n        <em>program,<\/em><br \/>\n        <em>including,<\/em><br \/>\n        <em>but<\/em><br \/>\n        <em>not<\/em><br \/>\n        <em>limited<\/em><br \/>\n        <em>to,<\/em><br \/>\n        <em>ATH434,<\/em><br \/>\n        <em>and<\/em><br \/>\n        <em>any<\/em><br \/>\n        <em>other<\/em><br \/>\n        <em>statements<\/em><br \/>\n        <em>that<\/em><br \/>\n        <em>are<\/em><br \/>\n        <em>not<\/em><br \/>\n        <em>historical facts.<\/em><br \/>\n        <em>Such<\/em><br \/>\n        <em>statements<\/em><br \/>\n        <em>involve<\/em><br \/>\n        <em>risks<\/em><br \/>\n        <em>and<\/em><br \/>\n        <em>uncertainties,<\/em><br \/>\n        <em>including,<\/em><br \/>\n        <em>but<\/em><br \/>\n        <em>not<\/em><br \/>\n        <em>limited<\/em><br \/>\n        <em>to,<\/em><br \/>\n        <em>those<\/em><br \/>\n        <em>risks<\/em><br \/>\n        <em>and<\/em><br \/>\n        <em>uncertainties<\/em><br \/>\n        <em>relating<\/em><br \/>\n        <em>to<\/em><br \/>\n        <em>the difficulties<\/em><br \/>\n        <em>or<\/em><br \/>\n        <em>delays<\/em><br \/>\n        <em>in<\/em><br \/>\n        <em>financing,<\/em><br \/>\n        <em>development,<\/em><br \/>\n        <em>testing,<\/em><br \/>\n        <em>regulatory<\/em><br \/>\n        <em>approval,<\/em><br \/>\n        <em>production<\/em><br \/>\n        <em>and<\/em><br \/>\n        <em>marketing<\/em><br \/>\n        <em>of<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>Company\u2019s<\/em><br \/>\n        <em>drug components,<\/em><br \/>\n        <em>including,<\/em><br \/>\n        <em>but<\/em><br \/>\n        <em>not<\/em><br \/>\n        <em>limited<\/em><br \/>\n        <em>to,<\/em><br \/>\n        <em>ATH434,<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>ability<\/em><br \/>\n        <em>of<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>Company<\/em><br \/>\n        <em>to<\/em><br \/>\n        <em>procure<\/em><br \/>\n        <em>additional<\/em><br \/>\n        <em>future<\/em><br \/>\n        <em>sources<\/em><br \/>\n        <em>of<\/em><br \/>\n        <em>financing, unexpected adverse side effects or inadequate therapeutic efficacy of the Company&#8217;s drug compounds, including, but not limited<\/em><br \/>\n        <em>to,<\/em><br \/>\n        <em>ATH434,<\/em><br \/>\n        <em>that<\/em><br \/>\n        <em>could<\/em><br \/>\n        <em>slow<\/em><br \/>\n        <em>or prevent products<\/em><br \/>\n        <em>coming<\/em><br \/>\n        <em>to<\/em><br \/>\n        <em>market,<\/em><br \/>\n        <em>the uncertainty<\/em><br \/>\n        <em>of obtaining patent protection<\/em><br \/>\n        <em>for<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>Company&#8217;s intellectual<\/em><br \/>\n        <em>property<\/em><br \/>\n        <em>or<\/em><br \/>\n        <em>trade<\/em><br \/>\n        <em>secrets, the uncertainty of successfully enforcing the Company\u2019s patent rights and the uncertainty of the Company freedom to operate.<\/em>\n      <\/p>\n<p align=\"justify\">\n        <em>Any forward-looking statement made by us in this press release is based only on information currently available to us and speaks<\/em><br \/>\n        <em>only<\/em><br \/>\n        <em>as<\/em><br \/>\n        <em>of<\/em><br \/>\n        <em>the<\/em><br \/>\n        <em>date<\/em><br \/>\n        <em>on<\/em><br \/>\n        <em>which<\/em><br \/>\n        <em>it<\/em><br \/>\n        <em>is<\/em><br \/>\n        <em>made.<\/em><br \/>\n        <em>We<\/em><br \/>\n        <em>undertake<\/em><br \/>\n        <em>no<\/em><br \/>\n        <em>obligation<\/em><br \/>\n        <em>to<\/em><br \/>\n        <em>publicly<\/em><br \/>\n        <em>update<\/em><br \/>\n        <em>any<\/em><br \/>\n        <em>forward-looking<\/em><br \/>\n        <em>statement, whether<\/em><br \/>\n        <em>written<\/em><br \/>\n        <em>or<\/em><br \/>\n        <em>oral,<\/em><br \/>\n        <em>that<\/em><br \/>\n        <em>may<\/em><br \/>\n        <em>be<\/em><br \/>\n        <em>made<\/em><br \/>\n        <em>from<\/em><br \/>\n        <em>time<\/em><br \/>\n        <em>to<\/em><br \/>\n        <em>time,<\/em><br \/>\n        <em>whether<\/em><br \/>\n        <em>as<\/em><br \/>\n        <em>a<\/em><br \/>\n        <em>result<\/em><br \/>\n        <em>of<\/em><br \/>\n        <em>new<\/em><br \/>\n        <em>information,<\/em><br \/>\n        <em>future<\/em><br \/>\n        <em>developments<\/em><br \/>\n        <em>or otherwise.<\/em>\n      <\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgwMDczMCM3NzUwNzAyIzIyNTY3MTM=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/YjFlODMyY2MtZDIwMy00ZWU2LWE4YjMtYzJiYTNjNTQwNDUyLTEyNjgyNjItMjAyNi0wNy0zMC1lbg==\/tiny\/ALTERITY-THERAPEUTICS-LIMITED.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Highlights FDA End-of-Phase 2 (EOP2) meeting minutes confirmed a registrational pathway for ATH434 in Multiple System Atrophy (MSA) FDA agreed that a single pivotal Phase 3 trial plus confirmatory evidence could support an approval of ATH434 for the treatment of MSA Pivotal Phase 3 trial activities on track to initiate by year-end 2026 Continued evaluation of strategic funding and partnering alternatives to support Phase 3 development and maximise long-term shareholder value Peer-reviewed publication in NeuroImage validated quantitative susceptibility mapping (QSM) of iron on MRI as a biomarker of MSA Strengthened the Board of Directors with the appointment of Ms Ann Cunningham A$3.98 million Australian R&amp;D Tax Incentive refund received subsequent to quarter end, supporting continued development of Alterity\u2019s clinical programs &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/alterity-therapeutics-releases-appendix-4c-q4-fy26-quarterly-cash-flow-report-corporate-update\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Alterity Therapeutics Releases Appendix 4C \u2013 Q4 FY26 Quarterly Cash Flow Report &amp; Corporate Update&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-987139","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Alterity Therapeutics Releases Appendix 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activities on track to initiate by year-end 2026 Continued evaluation of strategic funding and partnering alternatives to support Phase 3 development and maximise long-term shareholder value Peer-reviewed publication in NeuroImage validated quantitative susceptibility mapping (QSM) of iron on MRI as a biomarker of MSA Strengthened the Board of Directors with the appointment of Ms Ann Cunningham A$3.98 million Australian R&amp;D Tax Incentive refund received subsequent to quarter end, supporting continued development of Alterity\u2019s clinical programs &hellip; Continue reading &quot;Alterity Therapeutics Releases Appendix 4C \u2013 Q4 FY26 Quarterly Cash Flow Report &amp; Corporate Update&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/alterity-therapeutics-releases-appendix-4c-q4-fy26-quarterly-cash-flow-report-corporate-update\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta 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