{"id":966240,"date":"2026-05-21T18:26:31","date_gmt":"2026-05-21T22:26:31","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/"},"modified":"2026-05-21T18:26:31","modified_gmt":"2026-05-21T22:26:31","slug":"natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/","title":{"rendered":"Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwlistdisc { list-style-type: disc }\n.bwuline { text-decoration: underline }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology<\/b><\/p>\n<p class=\"bwalignc\"><i>Overall program, including 3 oral presentations, delivers unmatched evidence across the MRD landscape<\/i><\/p>\n<p>AUSTIN, Texas&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.natera.com&amp;esheet=54540493&amp;newsitemid=20260521853793&amp;lan=en-US&amp;anchor=Natera%2C+Inc.&amp;index=1&amp;md5=ac6eae73560f54cc2294351bdb1a8c51\">Natera, Inc.<\/a> (NASDAQ: NTRA), a global leader in cell-free DNA and precision medicine, today announced a landmark oncology data program for the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting. The meeting will take place May 29\u2013June 2 in Chicago, IL.<\/p>\n<p>\nTogether with its collaborators, Natera will demonstrate <b>unmatched scale in evidence generation with 35 abstracts <\/b>across molecular residual disease (MRD) testing and other innovations. Presentations will highlight Natera\u2019s Treatment on MRD (TOMR) approach, showing more precise intervention upon molecular recurrence; the broad utility of Signatera as a pan-cancer foundational tool in MRD; the robust clinical performance of Natera\u2019s ultrasensitive phased variant technology; and new real-world data on Signatera in hereditary risk assessment, treatment response monitoring, and longitudinal disease management.<\/p>\n<p>\n\u201cThis is the most comprehensive oncology data program Natera has presented to date, reflecting the growing adoption of Signatera and the accelerating momentum behind precision MRD-guided care,\u201d said Alexey Aleshin, M.D., corporate chief medical officer and general manager of oncology. \u201cCollectively, these studies reinforce Signatera\u2019s broad clinical utility, highlight the continued advancement of our technology platform, and demonstrate the strength and depth of our evidence as we work to make cancer care more actionable and personalized.\u201d<\/p>\n<p><b><span class=\"bwuline\">Treatment on MRD (TOMR) in Colorectal Cancer (CRC)<\/span><\/b><\/p>\n<p>\nMultiple analyses from the GALAXY study in CRC demonstrate the value of serial Signatera testing and the potential impact of MRD-guided decision making in the adjuvant setting.<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nIn one analysis, patients who were initially Signatera-negative but later converted to Signatera-positive derived a substantial benefit from adjuvant chemotherapy (ACT) (HR 0.3), showing Signatera can identify a subset of patients with early molecular recurrence who could benefit from ACT. Patients with sustained negativity had excellent outcomes regardless of ACT, suggesting potential overtreatment.<\/p>\n<\/li>\n<li>\nA separate analysis showed that extending ACT beyond three months provided no added benefit for patients with sustained Signatera-negativity or Signatera clearance, whereas partial molecular responders (decrease in ctDNA) benefitted from continued ACT. Molecular progression (increase in ctDNA) on ACT indicated the need for more effective alternative treatment strategies.<\/p>\n<\/li>\n<\/ul>\n<p><b><span class=\"bwuline\">Pan-Cancer MRD<\/span><\/b><\/p>\n<p>\nNatera will present a large, first-of-its-kind, real-world meta-analysis of Signatera across 18 published studies, more than 3,000 patients, and 15 tumor types. The analysis demonstrated that Signatera-positivity was strongly associated with increased risk of recurrence or disease progression at all timepoints included in the analysis.<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nIn a pooled analysis, Signatera-positivity in the adjuvant window was associated with significantly increased risk of recurrence or death (HR: 8.15).<\/p>\n<\/li>\n<li>\nIn the surveillance setting, Signatera-positivity was associated with an even greater recurrence risk (HR: 18.30).<\/p>\n<\/li>\n<\/ul>\n<p><b><span class=\"bwuline\">Phased Variant Technology<\/span><\/b><\/p>\n<p>\nNatera\u2019s phased variant technology continues to demonstrate powerful prognostic performance across both solid and hematologic cancers. This technology, which can detect circulating tumor DNA (ctDNA) levels below 1 part per 10 million, reinforces the potential of ultra-sensitive ctDNA detection to guide treatment response monitoring and long-term disease management.<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nOne study in early-stage, non-small cell lung cancer (NSCLC), showed that 100% of patients who cleared ctDNA during or after adjuvant therapy did not recur. ctDNA detection also preceded recurrence in 94% of cases.<\/p>\n<\/li>\n<li>\nIn a separate analysis in relapsed or refractory follicular lymphoma, patients treated with CAR T cell therapy who achieved MRD-negativity experienced substantially improved progression-free survival (PFS), including 36-month PFS rates of 81% compared to 56% in MRD-positive patients.<\/p>\n<\/li>\n<\/ul>\n<p><b><span class=\"bwuline\">Platform Expansion: RWD and New Digital Tools<\/span><\/b><\/p>\n<p>\nNatera and its collaborators will present real world data evaluating ctDNA dynamics and clinical outcomes in colorectal cancer, NSCLC, breast cancer, and additional tumor types. Natera will also unveil its Annotation platform at ASCO, a new digital tool that integrates clinical, treatment, and genomic data to present multimodal, longitudinal patient journeys through a unified interface, bringing richer clinical context to Signatera results at the individual and cohort levels.<\/p>\n<p>\nA full list of abstracts is included <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.natera.com%2Fevents%2Fnatera-at-american-society-of-clinical-oncology-asco%2F&amp;esheet=54540493&amp;newsitemid=20260521853793&amp;lan=en-US&amp;anchor=here&amp;index=2&amp;md5=c5aca1fffe1c6823f2cf525b3efc9314\">here<\/a>.<\/p>\n<p><b>About Natera<\/b><\/p>\n<p>\nNatera\u2122 is a global leader in cell-free DNA and precision medicine, dedicated to oncology, women\u2019s health, and organ health. We aim to make personalized genetic testing and diagnostics part of the standard-of-care to protect health and inform earlier, more targeted interventions that help lead to longer, healthier lives. Natera\u2019s tests are supported by more than 400 peer-reviewed publications that demonstrate excellent performance. Natera operates ISO 13485-certified and CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in Austin, Texas, and San Carlos, California, and through Foresight Diagnostics, its subsidiary, operates an ISO 27001-certified and CAP-accredited laboratory certified under CLIA in Boulder, Colorado. For more information, visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.natera.com&amp;esheet=54540493&amp;newsitemid=20260521853793&amp;lan=en-US&amp;anchor=www.natera.com&amp;index=3&amp;md5=a3eb86759dc0a2a4424879160e95456c\">www.natera.com<\/a>.<\/p>\n<p><b>Forward-Looking Statements<\/b><\/p>\n<p>\nAll statements other than statements of historical facts contained in this press release are forward-looking statements and are not a representation that Natera\u2019s plans, estimates, or expectations will be achieved. These forward-looking statements represent Natera\u2019s expectations as of the date of this press release, and Natera disclaims any obligation to update the forward-looking statements. These forward-looking statements are subject to known and unknown risks and uncertainties that may cause actual results to differ materially, including with respect to our efforts to develop and commercialize new product offerings, whether the results of clinical or other studies will support the use of our product offerings, the impact of results of such studies, our expectations of the reliability, accuracy, and performance of our tests, or of the benefits of our tests and product offerings to patients, providers, and payers. Additional risks and uncertainties are discussed in greater detail in &#8220;Risk Factors&#8221; in Natera\u2019s recent filings on Forms 10-K and 10-Q, and in other filings Natera makes with the SEC from time to time. These documents are available at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Finvestor.natera.com%2Fnews%2Fdefault.aspx&amp;esheet=54540493&amp;newsitemid=20260521853793&amp;lan=en-US&amp;anchor=www.natera.com%2Finvestors&amp;index=4&amp;md5=93bca359944d1dc01bf2bc69a38b5a38\">www.natera.com\/investors<\/a> and <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.sec.gov%2F&amp;esheet=54540493&amp;newsitemid=20260521853793&amp;lan=en-US&amp;anchor=www.sec.gov&amp;index=5&amp;md5=551179c8a43a5303b17a45c4a1298d6f\">www.sec.gov<\/a>.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260521853793r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20260521853793\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20260521853793\/en\/<\/a><\/span><\/p>\n<p>\nInvestor Relations: Mike Brophy, CFO, Natera, Inc., <a rel=\"nofollow\" href=\"mailto:investor@natera.com\">investor@natera.com<br \/>\n<\/a><br \/>Media: Lesley Bogdanow, VP of Corporate Communications, Natera, Inc., <a rel=\"nofollow\" href=\"mailto:pr@natera.com\">pr@natera.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> Illinois Texas United States North America<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Science Biotechnology Research Pharmaceutical Oncology Health Genetics Clinical Trials<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20260521853793\/en\/1736351\/3\/Natera_floret_Logo.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology Overall program, including 3 oral presentations, delivers unmatched evidence across the MRD landscape AUSTIN, Texas&#8211;(BUSINESS WIRE)&#8211;Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA and precision medicine, today announced a landmark oncology data program for the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting. The meeting will take place May 29\u2013June 2 in Chicago, IL. Together with its collaborators, Natera will demonstrate unmatched scale in evidence generation with 35 abstracts across molecular residual disease (MRD) testing and other innovations. Presentations will highlight Natera\u2019s Treatment on MRD (TOMR) approach, showing more precise intervention upon molecular recurrence; the broad utility of Signatera as a pan-cancer foundational tool &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-966240","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology Overall program, including 3 oral presentations, delivers unmatched evidence across the MRD landscape AUSTIN, Texas&#8211;(BUSINESS WIRE)&#8211;Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA and precision medicine, today announced a landmark oncology data program for the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting. The meeting will take place May 29\u2013June 2 in Chicago, IL. Together with its collaborators, Natera will demonstrate unmatched scale in evidence generation with 35 abstracts across molecular residual disease (MRD) testing and other innovations. Presentations will highlight Natera\u2019s Treatment on MRD (TOMR) approach, showing more precise intervention upon molecular recurrence; the broad utility of Signatera as a pan-cancer foundational tool &hellip; Continue reading &quot;Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-21T22:26:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260521853793r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology\",\"datePublished\":\"2026-05-21T22:26:31+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\\\/\"},\"wordCount\":1009,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20260521853793r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\\\/\",\"name\":\"Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology - 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(NASDAQ: NTRA), a global leader in cell-free DNA and precision medicine, today announced a landmark oncology data program for the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting. The meeting will take place May 29\u2013June 2 in Chicago, IL. Together with its collaborators, Natera will demonstrate unmatched scale in evidence generation with 35 abstracts across molecular residual disease (MRD) testing and other innovations. Presentations will highlight Natera\u2019s Treatment on MRD (TOMR) approach, showing more precise intervention upon molecular recurrence; the broad utility of Signatera as a pan-cancer foundational tool &hellip; Continue reading \"Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/","og_site_name":"Market Newsdesk","article_published_time":"2026-05-21T22:26:31+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260521853793r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology","datePublished":"2026-05-21T22:26:31+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/"},"wordCount":1009,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260521853793r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-to-present-35-studies-at-asco-extending-clinical-data-leadership-in-oncology\/","name":"Natera to Present 35 Studies at ASCO, Extending Clinical Data Leadership in Oncology - 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