{"id":965479,"date":"2026-05-20T17:40:45","date_gmt":"2026-05-20T21:40:45","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/"},"modified":"2026-05-20T17:40:45","modified_gmt":"2026-05-20T21:40:45","slug":"equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/","title":{"rendered":"Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis"},"content":{"rendered":"<h2>\nVirtual webinar to be held on Wednesday, May 27 at 11:00 AM ET<br \/>\n<\/h2>\n<div class=\"mw_release\">\n<p align=\"left\">LA JOLLA, Calif., May  20, 2026  (GLOBE NEWSWIRE) &#8212; <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=1ljr2rozuQOGV-Jh7vydLnZSQZ779eLxyqS2bfV6sgevpPDYgLJ0l989T-KZcbBY_3IBA_R8xEeW_7qRWtZrRQH-7W-nmrMrGkkas8QwLBU7pivWoxClqkOt1mCvSJtB\" rel=\"nofollow\" target=\"_blank\">Equillium<\/a>, Inc. (Nasdaq: EQ), a biotechnology innovator developing novel therapies to treat severe autoimmune and inflammatory disorders, today announced it will host a virtual investor event on Wednesday, May 27, 2026, at 11:00 AM ET.<\/p>\n<p align=\"left\">The event will be presented by Stephen Connelly Ph.D., Equillium\u2019s Chief Scientific Officer, and include new preclinical data evaluating several clinically relevant AhR modulators and further characterization of the relationship between AhR activation and miR-124 induction in both immune and epithelial cells.<\/p>\n<p align=\"left\">AhR is a xenosensor essential for maintaining intestinal barrier function and immune homeostasis and its activation initiates a wide transcriptional cascade, driving expression of multiple downstream genes and regulatory micro\u2011RNA (miR). Of particular interest is miR-124, where published studies in cell and mouse models demonstrated that miR-124 overexpression decreases AhR expression and promotes inflammation, whereas inhibition of miR-124 reduces inflammation. However, these data conflict with the observed anti-inflammatory effects of obefazimod, a drug known to induce miR-124 that has shown clinical efficacy in the treatment of ulcerative colitis. Despite its biological and therapeutic relevance, the paradoxical relationship between AhR and miR-124 has remained elusive and controversial.<\/p>\n<p align=\"left\">The webinar will present new data and insights that support a unifying mechanistic framework linking ligand-dependent AhR signaling to miR-124. These findings have important implications for both mechanistic interpretation and the rational development of therapies targeting the AhR\/miR-124 axis in inflammatory disease.<\/p>\n<p align=\"left\">A live question-and-answer session with management will follow the formal presentations. To register for the event, please click <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=QVrFSOE8tTcM-WR9VE_7EVHV6VSiVLm94L-jCVPkCv178Bq4429VzvTHy5ltgb5KNoxD05YTUl4zNJM6vkPIUklTOoVMuw_jZ5--_RUnO3g=\" rel=\"nofollow\" target=\"_blank\">here<\/a>. A replay of the webinar will be accessible in the <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=zWSTk2ZlCNtDkRtlbkDw3BNlPg59Av_bHqlBp8dmW1etq9wlwrsbO5F_1AN6hFvYGuYZpc_PFqsPVHzq_dDQoC_R4D5yb9yJ6lCSWzf3UFg2RrCuIh36UDeqXdYgO51yi7mzdxtP8hl-GVz1M3FAYQ==\" rel=\"nofollow\" target=\"_blank\">Investors section<\/a> of Equillium\u2019s website following the event.<\/p>\n<p align=\"left\">\n        <strong>About EQ504<\/strong><br \/>\n        <br \/>EQ504 is an investigational potent and selective aryl hydrocarbon receptor (AhR) modulator with a multi-modal, non-immunosuppressive mechanism of action designed to be complementary to other inflammation and immunology agents. AhR is critical to barrier organ tissue physiology and immunology, maintaining barrier function and promoting tissue repair and regeneration, while regulating resident immune cells with anti-inflammatory responses. EQ504\u2019s preclinical properties provide the potential for targeted, local delivery via enteric coating for the treatment of ulcerative colitis and other gastrointestinal diseases or inhaled formulations for the treatment of inflammatory lung diseases.<\/p>\n<p align=\"left\">\n        <strong>About Equillium\u00a0<\/strong><br \/>\n        <br \/>Equillium is a biotechnology innovator with a mission to develop highly impactful therapies to treat severe autoimmune and inflammatory disorders. <\/p>\n<p align=\"left\">For more information, visit\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=59dgq-T9bPC4YXqtOBqYCFvxjGHcI1Aqiho8unGEa4JE3b4Tu_dDYPntksZyoDo1VNChQ5idlekRbhy9QM6tdTEHd0W_29su5PvVOZOO3VyCVte4g1UmMdzo_yxCDdPx\" rel=\"nofollow\" target=\"_blank\">www.equilliumbio.com<\/a>.<\/p>\n<p align=\"left\">\n        <strong>Investor Contact<\/strong><br \/>\n        <br \/>PJ Kelleher<br \/>LifeSci Advisors, LLC<br \/>+1-617-430-7579<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=2Kl8jECfHXG_8rqZOs5oloYj2bs0IkCDBKFxov7zC39sGskNpuz18tmZ_HevhC99CAG8kQyTKt2Hyl9lxWdMeRTezDKM9jRTdW2jM9_qJHMKDdBvSOGdtQPhWiYEycilo8xDBkDVT7FUqS8vQFkG2mNizxTFQPSQ50wVZHxkCkw7zg-OCgV2ORPO99k2w01OKTyP--59_BllxctJ1-j5KCQ540bY_jsffnIKpe3P9hb3F2HPD1sGvDAecPgGGhYnSDqZYlbQqeT_N58yCpw-y-pFpbuukXBYf7e7MPdlisrdTSS_Zys-GLF9OT8XC_NH\" rel=\"nofollow\" target=\"_blank\">pkelleher@lifesciadvisors.com<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTcyNDA2OCM3NjEzNjkyIzUwMDE1Mjg5Ng==\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/YzgyNTAxZTEtODMwNC00ZjJjLWFiMDMtZWZmMDIwZTQzNjIyLTUwMDE1Mjg5Ni0yMDI2LTA1LTIwLWVu\/tiny\/Equillium-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Virtual webinar to be held on Wednesday, May 27 at 11:00 AM ET LA JOLLA, Calif., May 20, 2026 (GLOBE NEWSWIRE) &#8212; Equillium, Inc. (Nasdaq: EQ), a biotechnology innovator developing novel therapies to treat severe autoimmune and inflammatory disorders, today announced it will host a virtual investor event on Wednesday, May 27, 2026, at 11:00 AM ET. The event will be presented by Stephen Connelly Ph.D., Equillium\u2019s Chief Scientific Officer, and include new preclinical data evaluating several clinically relevant AhR modulators and further characterization of the relationship between AhR activation and miR-124 induction in both immune and epithelial cells. AhR is a xenosensor essential for maintaining intestinal barrier function and immune homeostasis and its activation initiates a wide transcriptional cascade, &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-965479","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Virtual webinar to be held on Wednesday, May 27 at 11:00 AM ET LA JOLLA, Calif., May 20, 2026 (GLOBE NEWSWIRE) &#8212; Equillium, Inc. (Nasdaq: EQ), a biotechnology innovator developing novel therapies to treat severe autoimmune and inflammatory disorders, today announced it will host a virtual investor event on Wednesday, May 27, 2026, at 11:00 AM ET. The event will be presented by Stephen Connelly Ph.D., Equillium\u2019s Chief Scientific Officer, and include new preclinical data evaluating several clinically relevant AhR modulators and further characterization of the relationship between AhR activation and miR-124 induction in both immune and epithelial cells. AhR is a xenosensor essential for maintaining intestinal barrier function and immune homeostasis and its activation initiates a wide transcriptional cascade, &hellip; Continue reading &quot;Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-20T21:40:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTcyNDA2OCM3NjEzNjkyIzUwMDE1Mjg5Ng==\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis\",\"datePublished\":\"2026-05-20T21:40:45+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\\\/\"},\"wordCount\":434,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTcyNDA2OCM3NjEzNjkyIzUwMDE1Mjg5Ng==\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\\\/\",\"name\":\"Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis - 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(Nasdaq: EQ), a biotechnology innovator developing novel therapies to treat severe autoimmune and inflammatory disorders, today announced it will host a virtual investor event on Wednesday, May 27, 2026, at 11:00 AM ET. The event will be presented by Stephen Connelly Ph.D., Equillium\u2019s Chief Scientific Officer, and include new preclinical data evaluating several clinically relevant AhR modulators and further characterization of the relationship between AhR activation and miR-124 induction in both immune and epithelial cells. AhR is a xenosensor essential for maintaining intestinal barrier function and immune homeostasis and its activation initiates a wide transcriptional cascade, &hellip; Continue reading \"Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/","og_site_name":"Market Newsdesk","article_published_time":"2026-05-20T21:40:45+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTcyNDA2OCM3NjEzNjkyIzUwMDE1Mjg5Ng==","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis","datePublished":"2026-05-20T21:40:45+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/"},"wordCount":434,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTcyNDA2OCM3NjEzNjkyIzUwMDE1Mjg5Ng==","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/equillium-to-host-virtual-investor-event-to-share-new-insights-into-the-aryl-hydrocarbon-receptor-ahr-and-mir-124-axis\/","name":"Equillium to Host Virtual Investor Event to Share New Insights into the Aryl Hydrocarbon Receptor (AhR) and miR-124 Axis - 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