{"id":964257,"date":"2026-05-18T16:45:40","date_gmt":"2026-05-18T20:45:40","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/"},"modified":"2026-05-18T16:45:40","modified_gmt":"2026-05-18T20:45:40","slug":"neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/","title":{"rendered":"Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules"},"content":{"rendered":"<div class=\"xn-newslines\">\n<p class=\"xn-distributor\">PR Newswire<\/p>\n<\/p><\/div>\n<div class=\"xn-content\">\n<ul type=\"disc\">\n<li>Clinician survey showed 90% of patients with mild tardive dyskinesia experienced emotional, social or physical impairment<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>Following initiation of INGREZZA, 96% of patients with mild tardive dyskinesia showed clinician-reported improvement in uncontrolled movements; of those patients, 86% improved within 4 weeks<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>Reductions in involuntary movements with INGREZZA treatment were associated with improvements in overall functional status, independence, activities of daily living and ability to work<\/li>\n<\/ul>\n<p>\n        <span class=\"legendSpanClass\">SAN DIEGO<\/span>, <span class=\"legendSpanClass\">May 18, 2026<\/span> \/PRNewswire\/ &#8212; <a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=3585473140&amp;u=https%3A%2F%2Fwww.neurocrine.com%2F&amp;a=Neurocrine+Biosciences%2C+Inc.\" target=\"_blank\" rel=\"nofollow\">Neurocrine Biosciences, Inc.<\/a>\u00a0(Nasdaq:\u00a0NBIX) today announced the\u00a0presentation of new data from a clinician survey highlighting the functional impact experienced by patients with mild tardive dyskinesia (TD) severity and the impact of treatment with <a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=3230421156&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4412782-1%26h%3D601933544%26u%3Dhttps%253A%252F%252Fwww.ingrezza.com%252F%26a%3DINGREZZA%25C2%25AE%2B(valbenazine)%2Bcapsules&amp;a=INGREZZA%C2%AE+(valbenazine)+capsules\" target=\"_blank\" rel=\"nofollow\">INGREZZA<sup>\u00ae <\/sup>(valbenazine) capsules<\/a> in a real-world setting. In a subgroup analysis, nearly all patients with clinician-reported mild TD treated with INGREZZA experienced fewer uncontrolled movements, with most demonstrating symptom improvement within four weeks. Patients also showed widespread improvements in functional status, independence, ability to perform daily activities and ability to work. The findings are being presented at the American Psychiatric Association 2026 Annual Meeting, taking place May 16-20 in San Francisco.<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<p>\n          <a href=\"https:\/\/mma.prnewswire.com\/media\/678850\/Neurocrine_Biosciences_Logo.html\" target=\"_blank\" rel=\"nofollow\"><br \/>\n            <img decoding=\"async\" src=\"https:\/\/mma.prnewswire.com\/media\/678850\/Neurocrine_Biosciences_Logo.jpg\" title=\"(PRNewsfoto\/Neurocrine Biosciences, Inc.)\" alt=\"(PRNewsfoto\/Neurocrine Biosciences, Inc.)\" \/><br \/>\n          <\/a>\n        <\/p>\n<\/p><\/div>\n<p>&#8220;A growing body of evidence shows that even tardive dyskinesia identified as mild in severity can meaningfully disrupt patients&#8217; daily functioning, impacting their physical, social and emotional well-being,&#8221; said Sanjay Keswani, M.D., Chief Medical Officer, Neurocrine Biosciences. &#8220;These real-world results complement previously published patient-reported data highlighting both the functional impact of mild involuntary movements and the potential benefits of INGREZZA treatment. INGREZZA has been shown to improve tardive dyskinesia and associated functional outcomes that can help patients reclaim their independence and resume everyday activities.&#8221;<\/p>\n<p>The analysis was based on a previously conducted clinician survey of patient chart data and clinician recall evaluating TD symptoms, functional impairment and improvement following treatment with INGREZZA. The survey included adult patients with TD who initiated INGREZZA between January 1, 2024 and June 30, 2024, completed at least two months of treatment and had at least one follow-up visit. In total, 128 clinicians caring for 315 patients with TD on INGREZZA reported data.<\/p>\n<p>This analysis focused on a subgroup of patients (n=90) with mild movement severity as rated by clinicians using global severity categories aligned with the Abnormal Involuntary Movement Scale. Prior to treatment, clinicians reported that mild TD movements impacted functional status in 90% of patients and independence in 84% of patients, with commonly affected areas including emotional (88%), social (86%), speech (61%), dexterity (60%) and eating (56%) functions.<\/p>\n<p>Following the initiation of INGREZZA, nearly all patients (96%) with mild TD experienced clinician-reported improvements in uncontrolled movements. Of those patients, 86% improved in four weeks or less. Beyond improvements in uncontrolled movements, clinicians observed meaningful functional improvements across a range of daily life domains among patients with mild TD:<\/p>\n<ul type=\"disc\">\n<li>For patients with impacted functional status (n=81), almost all (96%) had improvement in overall functional status.<\/li>\n<li>Across all functional items, clinicians reported improvement in more than 90% of impacted patients, including those with impacted speech (n=55), dexterity (n=54), social status (n=77), emotional status (n=79) and activities of daily living, such as eating (n=50) and self-care (n=44).<\/li>\n<li>Among all patients, 83% (n=75\/90) achieved improvement in independence with treatment.<\/li>\n<li>Among patients who were employed or attending school, 70% (n=21\/30) experienced improved willingness or ability to work or attend school after initiating treatment.<\/li>\n<\/ul>\n<p>Findings from this survey and subpopulation analysis support the American Psychiatric Association clinical guidelines, which state that treatment with a vesicular monoamine transporter 2 inhibitor can be considered for patients with mild TD based on associated impairment or patient preference. This research adds to the growing body of evidence demonstrating the benefits of INGREZZA in patients with TD, including those with mild movements. In clinical studies, including the <a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=648362149&amp;u=https%3A%2F%2Fneurocrine.gcs-web.com%2Fnews-releases%2Fnews-release-details%2Fneurocrine-biosciences-presents-new-post-hoc-analysis-treatment&amp;a=Phase+4+KINECT-PRO%E2%84%A2+study\" target=\"_blank\" rel=\"nofollow\">Phase 4 KINECT-PRO\u2122 study<\/a>, INGREZZA has been shown to improve TD severity and patients have reported reductions in the physical, social and emotional burden of the condition. Together, these real-world and clinical data highlight the potential of INGREZZA to improve movements and associated functional outcomes in patients with TD, including those with mild involuntary movements prior to treatment.<\/p>\n<p>\n        <b>About Tardive<\/b>\u00a0<b>Dyskinesia<\/b>\u00a0<br \/>Tardive dyskinesia (TD) is a movement disorder that is characterized by uncontrolled,\u00a0abnormal\u00a0and repetitive movements of the face,\u00a0torso\u00a0and\/or other body parts, which may be disruptive and negatively\u00a0impact\u00a0patients. The condition is associated with taking certain kinds of mental health medicines (antipsychotics) that help control dopamine receptors in the brain. Taking antipsychotics commonly prescribed to treat mental illnesses such as major depressive disorder, bipolar disorder, schizophrenia and schizoaffective disorder and other prescription medicines (metoclopramide and prochlorperazine) used to treat gastrointestinal disorders are associated with TD. In patients with TD, these treatments are thought to result in irregular dopamine signaling in a region of the brain that controls movement. The symptoms of TD can be mild to severe and are often persistent and irreversible. TD is estimated to affect at least 800,000 adults in the U.S.\u00a0\u00a0<\/p>\n<p>\n        <b>About the KINECT-PRO\u2122<\/b>\u00a0<b>Phase 4 Study<\/b>\u00a0<\/p>\n<p>The KINECT-PRO\u2122 Phase 4, open-label study was designed to evaluate patient-reported outcomes on the use of INGREZZA<sup>\u00ae<\/sup>\u00a0(valbenazine) capsules in a tardive dyskinesia (TD) patient population reflective of real-world clinical practice. Participants had at least mild TD, were aware of and\u00a0experiencing\u00a0at least mild distress from their abnormal, involuntary movements and had a clinical diagnosis of schizophrenia, schizoaffective disorder, bipolar\u00a0disorder\u00a0or major depression. The KINECT-PRO study included a four-week screening period, a 24-week treatment period during which participants received 40 mg of INGREZZA once-daily for the first four weeks, followed by flexible dosing of\u00a040 mg,\u00a060 mg\u00a0or\u00a080 mg\u00a0once-daily based on individual treatment needs and a two-week safety follow-up period. Baseline socio-demographic and clinical characteristics of the participants were broadly\u00a0similar to\u00a0those of the KINECT<sup>\u00ae<\/sup>\u00a03 and KINECT<sup>\u00ae<\/sup>\u00a04 studies.\u00a0<\/p>\n<p>KINECT-PRO is the first and only study to specifically evaluate and\u00a0demonstrate\u00a0patient-reported improvement with vesicular monoamine transporter 2 inhibitor treatment on TD using multiple clinically validated scales, including the\u00a0<a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=587233969&amp;u=https%3A%2F%2Fjpro.springeropen.com%2Farticles%2F10.1186%2Fs41687-023-00679-4&amp;a=Tardive+Dyskinesia+Impact+Scale\" target=\"_blank\" rel=\"nofollow\">Tardive Dyskinesia Impact Scale<\/a>\u00a0(TDIS\u2122).\u00a0The TDIS is the only patient-reported outcome instrument designed for and\u00a0validated\u00a0in tardive dyskinesia patients that measures\u00a0the physical,\u00a0social\u00a0and emotional impact of the involuntary movements of the condition.\u00a0<\/p>\n<p>\n        <b>About INGREZZA<\/b><br \/>\n        <sup>\u00ae<\/sup>\u00a0<b>(valbenazine) Capsules and INGREZZA<\/b><sup>\u00ae<\/sup>\u00a0<b>SPRINKLE (valbenazine) Capsules<\/b>\u00a0<br \/>INGREZZA is a selective vesicular monoamine transporter 2 (VMAT2) inhibitor approved by the U.S. Food and Drug Administration for the treatment of adults with tardive dyskinesia and the treatment of chorea associated with Huntington&#8217;s disease (HD). Only INGREZZA offers a therapeutic dose from day one with no required titration.\u00a0\u00a0<\/p>\n<p>INGREZZA, developed by Neurocrine Biosciences, selectively inhibits VMAT2 with no appreciable binding affinity for VMAT1, dopaminergic (including D2), serotonergic, adrenergic,\u00a0histaminergic\u00a0or muscarinic receptors. While the specific way INGREZZA works to treat TD and HD chorea is not fully understood, INGREZZA is unique in that it selectively and specifically targets VMAT2 to inhibit the release of dopamine, a chemical in the brain that helps control movement. INGREZZA is believed to reduce extra dopamine signaling, which may lead to fewer uncontrollable movements.\u00a0\u00a0<\/p>\n<p>INGREZZA is studied across the widest range of patients. It is always one capsule, once\u00a0daily\u00a0and can be taken together with most stable mental health regimens such as antipsychotics or antidepressants. Only INGREZZA offers the benefit of a sprinkle formulation, INGREZZA SPRINKLE, for those who experience dysphagia, have difficulty swallowing or prefer not to swallow a pill. INGREZZA and INGREZZA SPRINKLE dosages approved for use are\u00a040 mg,\u00a060\u00a0mg\u00a0and\u00a080 mg\u00a0capsules.\u00a0\u00a0<\/p>\n<p>\n        <b>Important Information<\/b>\u00a0<\/p>\n<p>\n        <b>Approved Uses<\/b>\u00a0<br \/>INGREZZA<sup>\u00ae<\/sup>\u00a0(valbenazine) capsules or INGREZZA<sup>\u00ae<\/sup>\u00a0SPRINKLE (valbenazine) capsules are prescription medicines used to treat adults with:\u00a0<\/p>\n<ul type=\"disc\">\n<li>movements in the face, tongue, or other body parts that cannot be controlled (tardive dyskinesia).\u00a0<\/li>\n<li>involuntary movements (chorea) of Huntington&#8217;s disease. INGREZZA or INGREZZA SPRINKLE do not cure the cause of involuntary movements, and do not treat other symptoms of Huntington&#8217;s disease, such as problems with thinking or emotions.\u00a0<\/li>\n<\/ul>\n<p>It is not known if INGREZZA or INGREZZA SPRINKLE\u00a0is\u00a0safe and effective\u00a0in\u00a0children.\u00a0<\/p>\n<p>\n        <b>IMPORTANT SAFETY INFORMATION<\/b>\u00a0<\/p>\n<p>\n        <b>INGREZZA or INGREZZA SPRINKLE can cause serious side effects in people with Huntington&#8217;s disease,<\/b>\u00a0<b>including:<\/b>\u00a0<b>depression, suicidal thoughts, or suicidal actions.<\/b>\u202fTell your healthcare provider before you start taking INGREZZA or INGREZZA SPRINKLE if you have Huntington&#8217;s disease and are depressed (have untreated depression or depression that is not well controlled by medicine) or have suicidal thoughts. Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is especially important when INGREZZA or INGREZZA SPRINKLE is started and when the dose is changed. Call your healthcare provider right away if you become depressed, have unusual changes in mood or behavior, or have thoughts of hurting yourself.\u00a0<\/p>\n<p>\n        <b>Do not take INGREZZA or INGREZZA SPRINKLE if you:<\/b>\n      <\/p>\n<ul type=\"disc\">\n<li>are allergic to valbenazine, or any of the ingredients in INGREZZA or INGREZZA SPRINKLE.<\/li>\n<\/ul>\n<p>\n        <b>INGREZZA or INGREZZA SPRINKLE can cause serious side effects, including:<\/b>\n      <\/p>\n<ul type=\"disc\">\n<li>\n          <b>Allergic reactions. <\/b>Allergic reactions, including an allergic reaction that causes sudden swelling called angioedema, can happen after taking the first dose or after many doses of INGREZZA or INGREZZA SPRINKLE. Signs and symptoms of allergic reactions and angioedema include: trouble breathing or shortness of breath, swelling of your face, lips, eyelids, tongue, or throat, or other areas of your skin, trouble with swallowing, or rash, including raised, itchy red areas on your skin (hives). Swelling in the throat can be life-threatening and can lead to death. Stop taking INGREZZA or INGREZZA SPRINKLE and go to the nearest emergency room right away if you develop these signs and symptoms of allergic reactions and angioedema.<\/li>\n<li>\n          <b>Sleepiness and tiredness that could cause slow reaction times (somnolence and sedation). <\/b>Do not drive a car or operate dangerous machinery until you know how INGREZZA or INGREZZA SPRINKLE affects you. Drinking alcohol and taking other medicines may also cause sleepiness during treatment with INGREZZA or INGREZZA SPRINKLE.<\/li>\n<li>\n          <b>Heart rhythm problems (QT prolongation<\/b>)<b>.<\/b> INGREZZA or INGREZZA SPRINKLE may cause a heart rhythm problem known as QT prolongation. You have a higher chance of getting QT prolongation if you also take certain other medicines during treatment with INGREZZA or INGREZZA SPRINKLE. Tell your healthcare provider right away if you develop any signs or symptoms of QT prolongation, including: fast, slow, or irregular heartbeat (heart palpitations), shortness of breath, dizziness or lightheadedness, or fainting or feeling like you are going to faint.<\/li>\n<li>\n          <b>Neuroleptic Malignant Syndrome (NMS). <\/b>NMS is a serious condition that can lead to death. Call a healthcare provider right away or go to the nearest emergency room if you develop these symptoms and they do not have another obvious cause: high fever, stiff muscles, problems thinking, irregular pulse or blood pressure, increased sweating, or very fast or uneven heartbeat.<\/li>\n<li>\n          <b>Parkinson-like symptoms. <\/b>Symptoms include: body stiffness, drooling, trouble moving or walking, trouble keeping your balance, shaking (tremors), or falls.\u00a0<\/li>\n<\/ul>\n<p>\n        <b>Before taking INGREZZA or INGREZZA SPRINKLE, tell your healthcare provider about<\/b>\u00a0<b>all of<\/b>\u00a0<b>your medical conditions including if you:<\/b>\u202fhave liver or heart problems, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed.\u00a0<\/p>\n<p>\n        <b>Tell your healthcare provider about all the medicines you take,<\/b>\u202fincluding prescription and over-the-counter medicines, vitamins, and herbal supplements. Make sure you tell\u00a0all of\u00a0your healthcare providers that you are taking INGREZZA or INGREZZA SPRINKLE. Taking INGREZZA or INGREZZA SPRINKLE with certain other medicines may cause serious side effects.\u00a0Especially tell\u00a0your healthcare provider if you: take digoxin or take or have taken a monoamine oxidase inhibitor (MAOI) medicine. You should not take INGREZZA or INGREZZA SPRINKLE if you are taking, or have stopped taking, a MAOI within the last\u00a014 days.\u00a0<\/p>\n<p>\n        <b>The most common side effects of INGREZZA or INGREZZA SPRINKLE in people with tardive dyskinesia<\/b>\u202f<b>are\u202f<\/b>sleepiness and tiredness.\u00a0<\/p>\n<p>\n        <b>The most common side effects of INGREZZA or INGREZZA SPRINKLE in people with<\/b><br \/>\n        <b>chorea<\/b>\u00a0<b>associated with Huntington&#8217;s disease include<\/b>\u202fsleepiness and tiredness, raised itchy red areas on your skin (hives), rash, and trouble getting to sleep or staying asleep.\u00a0<\/p>\n<p>These are not\u00a0all of\u00a0the possible side effects of INGREZZA or INGREZZA SPRINKLE. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch at\u202f<a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=3255841897&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4450443-1%26h%3D1853703394%26u%3Dhttps%253A%252F%252Fc212.net%252Fc%252Flink%252F%253Ft%253D0%2526l%253Den%2526o%253D4296736-1%2526h%253D2311019741%2526u%253Dhttp%25253A%25252F%25252Fwww.fda.gov%25252Fmedwatch%2526a%253Dwww.fda.gov%25252Fmedwatch%26a%3Dwww.fda.gov%252Fmedwatch&amp;a=www.fda.gov%2Fmedwatch\" target=\"_blank\" rel=\"nofollow\"><b>www.fda.gov\/medwatch<\/b><\/a>\u202for call\u202f<b>1-800-FDA-1088.<\/b>\u00a0<\/p>\n<p>\n        <b>Dosage Forms and Strengths:<\/b>\u202fINGREZZA and INGREZZA SPRINKLE are available in\u202f40 mg,\u00a060 mg, and\u00a080 mg\u00a0capsules.\u00a0<\/p>\n<p>\n        <b>Please see full<\/b>\u00a0<a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=1681587731&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4450443-1%26h%3D1106650428%26u%3Dhttps%253A%252F%252Fpi.neurocrine.com%252Fingrezza%252FINGREZZA-Full-Prescribing-Information.pdf%26a%3DPrescribing%2BInformation&amp;a=Prescribing+Information\" target=\"_blank\" rel=\"nofollow\"><b>Prescribing Information<\/b><\/a><b>, including Boxed Warning, and<\/b>\u00a0<a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=3314831699&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4450443-1%26h%3D3934003914%26u%3Dhttps%253A%252F%252Fpi.neurocrine.com%252Fingrezza%252FINGREZZA-Medication-Guide.pdf%26a%3DMedication%2BGuide&amp;a=Medication+Guide\" target=\"_blank\" rel=\"nofollow\"><b>Medication Guide<\/b><\/a><b>.<\/b>\u00a0<\/p>\n<p>\n        <b>About<\/b>\u00a0<b>Neurocrine Biosciences, Inc.<\/b><br \/>Neurocrine Biosciences\u00a0is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company&#8217;s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington&#8217;s disease, classic congenital adrenal hyperplasia, hyperphagia in patients with Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit\u00a0<a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=1145375872&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4450443-1%26h%3D3502828688%26u%3Dhttps%253A%252F%252Fc212.net%252Fc%252Flink%252F%253Ft%253D0%2526l%253Den%2526o%253D4252873-1%2526h%253D4039787179%2526u%253Dhttps%25253A%25252F%25252Fwww.neurocrine.com%25252F%2526a%253Dneurocrine.com%26a%3Dneurocrine.com&amp;a=neurocrine.com\" target=\"_blank\" rel=\"nofollow\">neurocrine.com<\/a>, and follow the company on\u00a0<a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=4030090356&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4450443-1%26h%3D884458364%26u%3Dhttps%253A%252F%252Fc212.net%252Fc%252Flink%252F%253Ft%253D0%2526l%253Den%2526o%253D4252873-1%2526h%253D928986078%2526u%253Dhttps%25253A%25252F%25252Fwww.linkedin.com%25252Fcompany%25252Fneurocrine-biosciences%2526a%253DLinkedIn%26a%3DLinkedIn&amp;a=LinkedIn\" target=\"_blank\" rel=\"nofollow\">LinkedIn<\/a>,\u00a0<a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=1921556823&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4450443-1%26h%3D1730331693%26u%3Dhttps%253A%252F%252Fc212.net%252Fc%252Flink%252F%253Ft%253D0%2526l%253Den%2526o%253D4252873-1%2526h%253D3255611529%2526u%253Dhttps%25253A%25252F%25252Ftwitter.com%25252Fneurocrine%2526a%253DX%252B(formerly%252BTwitter)%26a%3DX&amp;a=X\" target=\"_blank\" rel=\"nofollow\">X<\/a>, <a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=2228140780&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4450443-1%26h%3D3526407131%26u%3Dhttps%253A%252F%252Fc212.net%252Fc%252Flink%252F%253Ft%253D0%2526l%253Den%2526o%253D4252873-1%2526h%253D1536396415%2526u%253Dhttps%25253A%25252F%25252Fwww.facebook.com%25252FNeurocrine%2526a%253DFacebook%26a%3DFacebook&amp;a=Facebook\" target=\"_blank\" rel=\"nofollow\">Facebook<\/a> and <a href=\"https:\/\/edge.prnewswire.com\/c\/link\/?t=0&amp;l=en&amp;o=4689295-1&amp;h=268877630&amp;u=https%3A%2F%2Fwww.youtube.com%2F%40NeurocrineBiosciencesInc&amp;a=YouTube\" target=\"_blank\" rel=\"nofollow\">YouTube<\/a>. (<i>*in collaboration with AbbVie<\/i>)<\/p>\n<p>The NEUROCRINE BIOSCIENCES Logo, NEUROCRINE, YOU DESERVE BRAVE SCIENCE, INGREZZA and KINECT are registered trademarks of Neurocrine Biosciences, Inc. KINECT-PRO and TDIS are trademarks of Neurocrine Biosciences, Inc.\u00a0<\/p>\n<p>\n        <b>Forward-Looking Statements<\/b>\u00a0<br \/>In addition to historical facts, this press release\u00a0contains\u00a0forward-looking statements that involve\u00a0a number of\u00a0risks and uncertainties. These statements include, but are not limited to, statements regarding the potential benefits to be derived from INGREZZA, the interpretation and potential relevance of the data described in this press release, including expectations as to how such data may relate to the therapeutic effects and clinical efficacy of INGREZZA, and the value INGREZZA may bring to patients. Factors that could cause actual results to differ materially from those stated or implied in the forward-looking statements include, but are not limited to, the following: risks and uncertainties as to whether the data described in this press release will be replicated in additional studies or will be predictive of efficacy or other clinical outcomes in subsequent clinical studies or real-world use of INGREZZA; risks and\u00a0uncertainties associated with Neurocrine Biosciences&#8217; business and finances in general, as well as risks\u00a0and uncertainties associated with the commercialization of INGREZZA; whether INGREZZA receives\u00a0adequate reimbursement from third-party payors; risks and uncertainties relating to competitive products\u00a0and technological changes that may limit demand for INGREZZA; risks associated with the Company&#8217;s\u00a0dependence on third parties for development and manufacturing activities related to INGREZZA, and the ability of the Company to manage these third parties; risks that additional regulatory submissions for\u00a0INGREZZA or other product candidates may not occur or be submitted in a timely manner; risks that the FDA or other regulatory authorities may make adverse decisions regarding INGREZZA; risks that post-\u00a0approval INGREZZA commitments or requirements may be delayed; risks that INGREZZA may be\u00a0precluded from commercialization by the proprietary or regulatory rights of third parties, or have\u00a0unintended side effects, adverse reactions or incidents of misuse; and other risks described in the\u00a0Company&#8217;s periodic reports filed with the Securities and Exchange Commission, including without\u00a0limitation the Company&#8217;s quarterly report on Form 10-Q for the quarter ended March 31, 2026. Neurocrine Biosciences disclaims any obligation to update the statements contained in this press release after the date hereof other than required by law.\u00a0<\/p>\n<p>\u00a9\u00a02026\u202fNeurocrine Biosciences, Inc. All Rights Reserved.\u00a0CAP-VBZ-US-0101\u00a0\u00a0 05\/2026<\/p>\n<p id=\"PURL\">\n        <img loading=\"lazy\" decoding=\"async\" title=\"Cision\" width=\"12\" height=\"12\" alt=\"Cision\" src=\"https:\/\/edge.prnewswire.com\/c\/img\/favicon.png?sn=LA60179&amp;sd=2026-05-18\" \/> View original content to download multimedia:<a id=\"PRNURL\" rel=\"nofollow\" href=\"https:\/\/www.prnewswire.com\/news-releases\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules-302774948.html\" target=\"_blank\">https:\/\/www.prnewswire.com\/news-releases\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules-302774948.html<\/a><\/p>\n<p>SOURCE Neurocrine Biosciences, Inc.<\/p>\n<\/p><\/div>\n<p>    <img decoding=\"async\" alt=\"\" src=\"https:\/\/rt.prnewswire.com\/rt.gif?NewsItemId=LA60179&amp;Transmission_Id=202605181605PR_NEWS_USPR_____LA60179&amp;DateId=20260518\" style=\"border:0px;width:1px;height:1px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>PR Newswire Clinician survey showed 90% of patients with mild tardive dyskinesia experienced emotional, social or physical impairment Following initiation of INGREZZA, 96% of patients with mild tardive dyskinesia showed clinician-reported improvement in uncontrolled movements; of those patients, 86% improved within 4 weeks Reductions in involuntary movements with INGREZZA treatment were associated with improvements in overall functional status, independence, activities of daily living and ability to work SAN DIEGO, May 18, 2026 \/PRNewswire\/ &#8212; Neurocrine Biosciences, Inc.\u00a0(Nasdaq:\u00a0NBIX) today announced the\u00a0presentation of new data from a clinician survey highlighting the functional impact experienced by patients with mild tardive dyskinesia (TD) severity and the impact of treatment with INGREZZA\u00ae (valbenazine) capsules in a real-world setting. In a subgroup analysis, nearly all patients &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-964257","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"PR Newswire Clinician survey showed 90% of patients with mild tardive dyskinesia experienced emotional, social or physical impairment Following initiation of INGREZZA, 96% of patients with mild tardive dyskinesia showed clinician-reported improvement in uncontrolled movements; of those patients, 86% improved within 4 weeks Reductions in involuntary movements with INGREZZA treatment were associated with improvements in overall functional status, independence, activities of daily living and ability to work SAN DIEGO, May 18, 2026 \/PRNewswire\/ &#8212; Neurocrine Biosciences, Inc.\u00a0(Nasdaq:\u00a0NBIX) today announced the\u00a0presentation of new data from a clinician survey highlighting the functional impact experienced by patients with mild tardive dyskinesia (TD) severity and the impact of treatment with INGREZZA\u00ae (valbenazine) capsules in a real-world setting. In a subgroup analysis, nearly all patients &hellip; Continue reading &quot;Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-18T20:45:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mma.prnewswire.com\/media\/678850\/Neurocrine_Biosciences_Logo.jpg\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"13 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules\",\"datePublished\":\"2026-05-18T20:45:40+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\\\/\"},\"wordCount\":2584,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mma.prnewswire.com\\\/media\\\/678850\\\/Neurocrine_Biosciences_Logo.jpg\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\\\/\",\"name\":\"Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/","og_locale":"en_US","og_type":"article","og_title":"Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules - Market Newsdesk","og_description":"PR Newswire Clinician survey showed 90% of patients with mild tardive dyskinesia experienced emotional, social or physical impairment Following initiation of INGREZZA, 96% of patients with mild tardive dyskinesia showed clinician-reported improvement in uncontrolled movements; of those patients, 86% improved within 4 weeks Reductions in involuntary movements with INGREZZA treatment were associated with improvements in overall functional status, independence, activities of daily living and ability to work SAN DIEGO, May 18, 2026 \/PRNewswire\/ &#8212; Neurocrine Biosciences, Inc.\u00a0(Nasdaq:\u00a0NBIX) today announced the\u00a0presentation of new data from a clinician survey highlighting the functional impact experienced by patients with mild tardive dyskinesia (TD) severity and the impact of treatment with INGREZZA\u00ae (valbenazine) capsules in a real-world setting. In a subgroup analysis, nearly all patients &hellip; Continue reading \"Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/","og_site_name":"Market Newsdesk","article_published_time":"2026-05-18T20:45:40+00:00","og_image":[{"url":"https:\/\/mma.prnewswire.com\/media\/678850\/Neurocrine_Biosciences_Logo.jpg","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"13 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules","datePublished":"2026-05-18T20:45:40+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/"},"wordCount":2584,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/#primaryimage"},"thumbnailUrl":"https:\/\/mma.prnewswire.com\/media\/678850\/Neurocrine_Biosciences_Logo.jpg","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/neurocrine-biosciences-presents-real-world-data-highlighting-functional-impact-of-mild-tardive-dyskinesia-severity-and-improvement-with-ingrezza-valbenazine-capsules\/","name":"Neurocrine Biosciences Presents Real-World Data Highlighting Functional Impact of Mild Tardive Dyskinesia Severity and Improvement with INGREZZA\u00ae (valbenazine) Capsules - 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