{"id":960655,"date":"2026-05-11T08:03:21","date_gmt":"2026-05-11T12:03:21","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/"},"modified":"2026-05-11T08:03:21","modified_gmt":"2026-05-11T12:03:21","slug":"charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/","title":{"rendered":"Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwlistdisc { list-style-type: disc }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow<\/b><\/p>\n<p>WILMINGTON, Mass.&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nCharles River Laboratories International, Inc. (NYSE: CRL) today announced continued momentum in its digital pathology platform, delivering an end-to-end, AI-enabled workflow that significantly accelerates study timelines, and enhances pathologist efficiency, and supports the reduction of animal use in nonclinical research where scientifically appropriate.<\/p>\n<p>\nBy fully integrating digital pathology across the histology and pathology workflow, Charles River is committed to cutting at least one week from standard pathology timelines while maintaining Good Laboratory Practice (GLP) rigor and regulatory readiness. These efficiency gains are driven by the combination of a fully integrated histology laboratory information management system (LIMS), AI-powered slide quality control (QC), and validated digital primary pathology reviews.<\/p>\n<p>\n\u201cDigital pathology isn\u2019t just about digitizing slides; it is about reengineering the entire workflow,\u201d said Danielle Brown, Digital Products Leader, Charles River. \u201cBy applying AI at critical bottlenecks and grounding our models in Charles River\u2019s unmatched pathology expertise and image libraries, we are delivering faster, more scalable, and more insightful pathology for our clients.\u201d<\/p>\n<p><b>Eliminating Bottlenecks Across the Histopathology Workflow<br \/>\n<br \/><\/b>Charles River\u2019s digital pathology workflow addresses one of the most time- and labor-intensive steps in histopathology: manual slide quality control. Traditionally, highly-trained technicians had to individually review every slide, creating delays before slides ever reached a pathologist.<\/p>\n<p>\nThrough an AI-powered QC platform, <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.criver.com%2Finsights%2Fdigital-pathology-here&amp;esheet=54531665&amp;newsitemid=20260511166704&amp;lan=en-US&amp;anchor=developed+in+partnership+with+Deciphex&amp;index=1&amp;md5=3d2b3125727be97d8069b2e76d59051a\">developed in partnership with Deciphex<\/a>, Charles River is systematically eliminating this bottleneck through a phased approach:<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nScanning QC (already in production), automatically detecting out-of-focus images, striping, and other scanning artifacts<\/p>\n<\/li>\n<li>\nHistology artifact QC, identifying tears, folds, bubbles, chatter, and related artifacts, targeted for release in Q3 2026<\/p>\n<\/li>\n<li>\nOrgan sub-compartment completeness QC, a first-of-its-kind capability confirming the presence of required organ substructures, targeted for Q1 2027<\/p>\n<\/li>\n<\/ul>\n<p>\nOnce fully deployed, this automated QC capability will remove an entire manual step from the histology process, shortening turnaround times while allowing skilled technical staff to focus on higher value activities.<\/p>\n<p>\nCharles River is also deploying a fully integrated end-to-end histology tracking and management system, Prima, which will create a completely seamless, paperless histology workflow to enhance quality and maximize efficiency.<\/p>\n<p><b>Validated Digital Reviews and AI-Driven Decision Support<br \/>\n<br \/><\/b>In parallel, Charles River has implemented GLP-validated digital primary pathology reviews, eliminating the need to physically ship glass slides and reducing pathology read times by an average of 20 percent. Digital reviews also enable broader collaboration across Charles River\u2019s global pathology network and create the foundation for advanced analytics.<\/p>\n<p>\nBuilding on this foundation, Charles River is deploying AI-powered decision support and anomaly detection, with the potential to further improve pathologist efficiency by more than 30 percent. Plans for GLP validation of these AI tools are being developed in alignment with FDA guidance and the EU AI Act, ensuring regulatory robustness alongside innovation.<\/p>\n<p><b>A Differentiated Platform Built on Unmatched Data and Expertise<br \/>\n<br \/><\/b>Charles River\u2019s digital pathology capabilities are uniquely differentiated by the scale, diversity, and quality of the data and expertise behind them:<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nAI models trained on Charles River\u2019s extensive global pathology image library, representing a uniquely diverse dataset across species, organs, and study types<\/p>\n<\/li>\n<li>\nThe industry\u2019s largest global network of pathologists (more than 150 experts) leveraged for image annotation, data curation, expert review, and rigorous model performance testing<\/p>\n<\/li>\n<li>\nTools trained on slides prepared in laboratories around the world and scanned on multiple platforms, ensuring robustness across real-world lab and scanner variability<\/p>\n<\/li>\n<\/ul>\n<p>\nThis depth of data and human expertise enables high-performing AI models with the sensitivity and specificity required for regulated, GLP environments, without creating additional downstream workload for histology labs or pathologists.<\/p>\n<p><b>Advancing the 3Rs Through Digital Innovation<br \/>\n<br \/><\/b>Digital pathology also enables the use of Virtual Control Groups (VCGs), leveraging historical digital slide data to reduce the number of control animals required for studies when scientifically appropriate. By expanding the use of high-quality digital slides, Charles River is helping clients advance the 3Rs (replacement, reduction, and refinement of animal use) while maintaining scientific rigor.<\/p>\n<p>\n\u201cOur digital pathology investments reflect the convergence of science, technology, and responsibility,\u201d said Dr. Namandj\u00e9 N. Bumpus, Chief Science and Innovation Officer, Charles River. \u201cThey allow us to deliver faster insights for our clients while actively supporting animal welfare and the future of more predictive research.\u201d<\/p>\n<p>\nCharles River remains committed to advancing the validation and acceptance of NAMs. Together with clients, regulators, and the industry, NAMs provide a foundation for a future where more patients gain access to life-saving treatments. The Digital Pathology program is guided by the Alternative Methods Advancement Project\u2122 (AMAP), an initiative focused on reducing the use of animals in research where scientifically appropriate.<\/p>\n<p><b>About the Alternative Methods Advancement Project (AMAP)<br \/>\n<br \/><\/b>The Alternative Methods Advancement Project (AMAP) is a Charles River-led initiative dedicated to developing New Approach Methodologies (NAMs) and exploring innovative scientific and technological solutions aimed at reducing reliance on traditional animal testing. As we enter the next frontier of drug development, AMAP\u2122 enables strategic, purpose-driven investment to shape a future in which more patients can access the treatments and medicines they need safely, swiftly, and successfully. AMAP is supported by our global, cross-functional <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.criver.com%2Fabout-us%2Fabout-us-overview%2Fnew-approach-methodologies%2Fscientific-advisory-board%3Fregion%3D3601&amp;esheet=54531665&amp;newsitemid=20260511166704&amp;lan=en-US&amp;anchor=Scientific+Advisory+Board&amp;index=2&amp;md5=119ddfed9455ae97cb8f743c0c767f2c\">Scientific Advisory Board<\/a> led by Dr. Namandj\u00e9 N. Bumpus.<\/p>\n<p><b>About Charles River<br \/>\n<br \/><\/b>Charles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. To learn more about our unique portfolio and breadth of services, visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.criver.com&amp;esheet=54531665&amp;newsitemid=20260511166704&amp;lan=en-US&amp;anchor=www.criver.com&amp;index=3&amp;md5=209b1b8984f341873f4f5a1f993cad2f\">www.criver.com<\/a>.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260511166704r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20260511166704\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20260511166704\/en\/<\/a><\/span><\/p>\n<p><b>Charles River Investor Contact:<br \/>\n<br \/><\/b>Todd Spencer<br \/>\n<br \/>Corporate Vice President,<br \/>\n<br \/>Investor Relations<br \/>\n<br \/>781.222.6455<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:todd.spencer@crl.com\">todd.spencer@crl.com<br \/>\n<\/a><\/p>\n<p><b>Charles River Media Contact:<br \/>\n<\/b><br \/>Amy Cianciaruso<br \/>\n<br \/>Corporate Senior Vice President,<br \/>\n<br \/>Chief Communications Officer<br \/>\n<br \/>781.222.6168<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:amy.cianciaruso@crl.com\">amy.cianciaruso@crl.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> Massachusetts United States North America<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Biotechnology Technology Health General Health Pharmaceutical Health Technology Other Science Medical Devices Research Artificial Intelligence Science<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20260511166704\/en\/836653\/3\/charles_river_logo.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow WILMINGTON, Mass.&#8211;(BUSINESS WIRE)&#8211; Charles River Laboratories International, Inc. (NYSE: CRL) today announced continued momentum in its digital pathology platform, delivering an end-to-end, AI-enabled workflow that significantly accelerates study timelines, and enhances pathologist efficiency, and supports the reduction of animal use in nonclinical research where scientifically appropriate. By fully integrating digital pathology across the histology and pathology workflow, Charles River is committed to cutting at least one week from standard pathology timelines while maintaining Good Laboratory Practice (GLP) rigor and regulatory readiness. These efficiency gains are driven by the combination of a fully integrated histology laboratory information management system (LIMS), AI-powered slide quality control (QC), and validated digital primary pathology reviews. \u201cDigital &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-960655","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow WILMINGTON, Mass.&#8211;(BUSINESS WIRE)&#8211; Charles River Laboratories International, Inc. (NYSE: CRL) today announced continued momentum in its digital pathology platform, delivering an end-to-end, AI-enabled workflow that significantly accelerates study timelines, and enhances pathologist efficiency, and supports the reduction of animal use in nonclinical research where scientifically appropriate. By fully integrating digital pathology across the histology and pathology workflow, Charles River is committed to cutting at least one week from standard pathology timelines while maintaining Good Laboratory Practice (GLP) rigor and regulatory readiness. These efficiency gains are driven by the combination of a fully integrated histology laboratory information management system (LIMS), AI-powered slide quality control (QC), and validated digital primary pathology reviews. \u201cDigital &hellip; Continue reading &quot;Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-11T12:03:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260511166704r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow\",\"datePublished\":\"2026-05-11T12:03:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\\\/\"},\"wordCount\":1010,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20260511166704r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\\\/\",\"name\":\"Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow - 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(NYSE: CRL) today announced continued momentum in its digital pathology platform, delivering an end-to-end, AI-enabled workflow that significantly accelerates study timelines, and enhances pathologist efficiency, and supports the reduction of animal use in nonclinical research where scientifically appropriate. By fully integrating digital pathology across the histology and pathology workflow, Charles River is committed to cutting at least one week from standard pathology timelines while maintaining Good Laboratory Practice (GLP) rigor and regulatory readiness. These efficiency gains are driven by the combination of a fully integrated histology laboratory information management system (LIMS), AI-powered slide quality control (QC), and validated digital primary pathology reviews. \u201cDigital &hellip; Continue reading \"Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/","og_site_name":"Market Newsdesk","article_published_time":"2026-05-11T12:03:21+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260511166704r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow","datePublished":"2026-05-11T12:03:21+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/"},"wordCount":1010,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260511166704r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-accelerates-digital-pathology-with-ai-powered-end-to-end-workflow\/","name":"Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow - 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