{"id":959759,"date":"2026-05-07T08:22:50","date_gmt":"2026-05-07T12:22:50","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\/"},"modified":"2026-05-07T08:22:50","modified_gmt":"2026-05-07T12:22:50","slug":"silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\/","title":{"rendered":"Silo Pharma Files Provisional Patent for Ibogaine-Based Therapeutic Targeting Traumatic Brain Injury"},"content":{"rendered":"<div class=\"mw_release\">\n<p>\n        <b><br \/>\n          <i>New initiative from Silo Pharma designed to align with federal actions to accelerate mental health innovation using psychedelic medicines<\/i><br \/>\n        <\/b>\n      <\/p>\n<p>\n        <b><br \/>\n          <i>Silo Pharma targets unmet need in a drug market with no FDA-approved therapies that address structural or regenerative aspects of traumatic brain injury <\/i><br \/>\n        <\/b>\n      <\/p>\n<p>\n        <b><br \/>\n          <i>Traumatic brain injury therapeutics market estimated to reach\u00a0$6 billion by 2032<\/i><br \/>\n        <\/b>\n      <\/p>\n<p>SARASOTA, FLA., May  07, 2026  (GLOBE NEWSWIRE) &#8212; Silo Pharma (Nasdaq: SILO) (\u201cSilo\u201d or \u201cthe Company\u201d), a developmental-stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced a strategic initiative to explore ibogaine-based therapeutics for the treatment of traumatic brain injury (TBI) and associated neuropsychiatric conditions.<\/p>\n<p>Silo has filed a provisional patent application with the United States Patent and Trademark Office (USPTO) titled \u201cCompositions and Methods for Treating Traumatic Brain Injuries and\/or Disorders Associated therewith with Ibogaine.\u201d The invention applies to the use of ibogaine and related compounds for the treatment of TBI, post-traumatic stress disorder (PTSD) and associated conditions.<\/p>\n<p>Silo\u2019s newest drug discovery initiative is in line with recently published clinical and neuroimaging findings demonstrating substantial improvements in patients with TBI following treatment with ibogaine-based protocols. Reported outcomes include significant reductions in depression and anxiety symptoms, as well as measurable structural brain changes, including increased cortical thickness, subcortical volume expansion, and reductions in predicted brain age following a single treatment.<\/p>\n<p>In accordance with the <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=L7qEDkqE02-NVYcvXk7pqWjHybIvC2H0lS9LZxJAgQu5ZJdEpim4t4fN6BDSnZg8WUaiiLsCgxiIbDppQbbOLDYhpxnprc8ry55ha-eFdAb3RFp1vPyLZP70LlYpOTD-LP-2gBW1deDvNWSScbTDluRc2IxP0yTr8oEeF6DoUdTjymtcbxXs92C1Jw-1pS1dkk0OjmVIZFON7QzhOFvuc8ZEyexiUF4ZOudW-MOv1lSnLpBAlDgu_DgJ1vXIV0ru7AqEcZ0IXOx7J7OkgjCmjI8EXbtdAkU37LKBum8ZmLuXeek8U9Fw2uh6MscIlvC9Tbain8yuU8epuW8i9zk6Ih6SFx4KWxYxHot235eotKSYM376Y5cJn3tu-eU2l7iU\" rel=\"nofollow\" target=\"_blank\">Executive Order<\/a> by President Trump announced on April 18, 2026, the FDA has granted Breakthrough Therapy designation to specific psychedelic drugs through a program designed to expedite the development and review of drugs intended to treat serious or life-threatening conditions. The Executive Order cites ibogaine\u2019s potential for conditions that persist after standard therapies are completed.<\/p>\n<p>\u201cPromising clinical findings on ibogaine signify a potential paradigm shift in how we think about treating traumatic brain injury and related central nervous system (CNS) disorders,\u201d said Eric Weisblum, CEO of Silo Pharma. \u201cWhile many drugs are used off label to manage TBI symptoms like cognitive dysfunction or depression, no pharmaceutical agent has ever received FDA approval for the direct treatment of TBI. The possibility of not only addressing symptoms but also driving measurable structural brain improvements opens a compelling new frontier in neurotherapeutics.\u201d<\/p>\n<p>Silo will evaluate the potential of ibogaine and related compounds, including differentiated protocols and combination approaches, as part of its broader strategy to develop next-generation psychedelics-assisted CNS therapeutics. The Company intends to explore treatment approaches designed to promote neuroplasticity, improve functional outcomes, and address the underlying pathophysiology of TBI.<\/p>\n<p>TBI remains a significant unmet medical need, particularly among military veterans and individuals with chronic neuropsychiatric symptoms. No FDA-approved treatments address structural or regenerative aspects of traumatic brain injury. Current options are limited to symptomatic support.<\/p>\n<p>The\u00a0global traumatic brain injury (TBI) therapeutics market\u00a0is estimated to reach\u00a0$6.0 billion by 2032, growing at a\u00a0CAGR of 6.0%\u00a0between\u00a02025 and 2032. Key drivers of growth include. The increasing incidence of brain injuries worldwide and rapid advancements in treatment options.<sup>1<\/sup><\/p>\n<p>\u201cBy expanding into ibogaine-based therapeutics, we are bolstering Silo\u2019s position at the intersection of emerging psychedelic research and next-generation CNS drug development,\u201d Weisblum added. \u201cSilo\u2019s broader strategy focuses on combining novel compounds, innovative delivery systems and measurable clinical endpoints to drive scalable therapeutic solutions.\u201d<\/p>\n<p>\n        <b>About Silo Pharma, Inc.<\/b>\n      <\/p>\n<p>Silo Pharma is a diversified developmental-stage biopharmaceutical and cryptocurrency treasury company. Its therapeutic focus is on addressing underserved conditions, including stress-induced psychiatric disorders, chronic pain, and central nervous system (CNS) diseases. The Company\u2019s portfolio includes innovative programs such as SPC-15 for PTSD, SP-26 for fibromyalgia and chronic pain, and preclinical assets targeting Alzheimer\u2019s disease. Silo\u2019s research is conducted in collaboration with leading universities and laboratories.\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=zqDnTpoKA9XTG_Vg2qHLwhpW2U4SGXgh0kTP5Xc0w1bmnxS5MQwsm3PKXCMmXzSr2UpcloXgHpC0lIdZT4LDMeTJms0px8EGuDkoLf_DfjGrss3M6Wy-k-x1q_El4oTWcOaA0Un-qh3yjIY_ZltlnLiiPuRhcX4PaWQphvlhPzur4TXIlUi5c13kAvrwFcSqftsYDvBL-asCgO7IH8mcFK5Prnmm1mS6BcDdcooPzo1pPkBghabMns-hNapWXKRnHvG6i8EVXlw3foG1peXT92R3LnGOQXZzsCrr8nbOekJLHmIoYtHDcleIejYa1H9pLAC_O70UX0erlctQnSRDiM-ydrIhLDzss3j397X2zLlkk02o9EgXRGk5fqzsJl1iw899516WP_0TQQjpsvSltAW31uLhHhuhlZfvMO4WcKC9RxAsLAKdbLE9L_LhdFwXw1DCVykO3aXUTZ5mCSnpeEmCZxgKL5gtS0_ajeGFHrc_tyMYeuzsI2RWnV8pameb_G7cJs1gM68doVh5LepwnReS2hMNQTV1x8MeLDfMXb5jac9yQT-7KdJ4PwAkW_jwumRLS0jYxoVUYnhQ1C8i37lMwyH8xnOJ4-_r9Ijd574O2bMwJLYLfHtvgmJek34f3ELGqRjNhPnwT7HEBRD1F8Cjrxv3UrZGlKPDFa9Eq_nOhxfoRZgibusi6_zCrb9GeuqL3ALjOC8bUtT5Yqss_FIApK3Q1KvjJt5_9pO5k9fVgQ4iR8BWWf0l15kqxgIXSqPqoayf6LksnHQyMwwiv0bM7opNfP5KEcrqV6_TXKAiAaFygnz9Hnki86OQ7CJpvBBGgJp2KCVkFRC8XPil8aF0mJcydGg9tIF973RFbcqOXv5tHqxRQFwAw78omVYy20otJ8dhH7shiqtw1Tr7ze0RSuCU_I51vyKjrCOfbYNF29SbMLieuct-tEAXqnYLaMiSGR9HvCivuJQPzIs1ghFqpKT0BsWnHXr1stWmrd8VrNgPB2qrp-5q9ar5AKscJ-fQL4Uzufk60WQvf9hOkA==\" rel=\"nofollow\" target=\"_blank\"><u>silopharma.com<\/u><\/a><\/p>\n<p>\n        <b>Forward Looking Statements<\/b>\n      <\/p>\n<p>This news release contains \u201cforward-looking statements\u201d within the meaning of the \u201csafe harbor\u201d provisions of the Private Securities Litigation Reform Act of 1995. These statements are identified using words \u201ccould\u201d, \u201cbelieve\u201d, \u201canticipate\u201d, \u201cintend\u201d, \u201cestimate\u201d, \u201cexpect\u201d, \u201cmay\u201d, \u201ccontinue\u201d, \u201cpredict\u201d, \u201cpotential\u201d, and similar expressions that are intended to identify forward-looking statements. Such statements involve known and unknown risks, uncertainties, and other factors that could cause the actual results of the Company to differ materially from the results expressed or implied by such statements, including statements about the intended use of proceeds from the offering, changes to anticipated sources of revenues, future economic and competitive conditions, difficulties in developing the Company\u2019s technology platforms, retaining and expanding the Company\u2019s customer base, fluctuations in consumer spending on the Company\u2019s products and other factors. Accordingly, although the Company believes that the expectations reflected in such forward-looking statements are reasonable, there can be no assurance that such expectations will prove to be correct. The Company disclaims any obligations to publicly update or release any revisions to the forward-looking information contained in this press release, whether as a result of new information, future events, or otherwise, after the date of this press release or to reflect the occurrence of unanticipated events except as required by law.<\/p>\n<p>\n        <b>Contact<\/b><br \/>\n        <br \/>(800) 705-0120<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=-G7oNjo3YX1iG6ZUdnz4ReEE-X01J_JH4xe-IhOEiXX2u458U9r3Tdlut8MjkXT5mQaLwis7ZEGi5ZKz0tAPSdZ0pYK--i1uNHLCmyRp9Ayrfyo0jJ7qQj7LRtJWkokWffkIozDyMLW560EozREQ-pe-AU6iLF3huzGrdfBc61Reo756_vmtWwM3pcbsq3ynkgcPqR_KBGi8JSF94d6ehmTOIPbWpKnNzKs7njXvNRNiKwyVpQBHj-LMKDysLHocWh7wqYt6m9OS0HzlTFbdfLOEM3dNbYUznFv2D--bxSZc5rLTlyyPhRrsY1aAGGaq78AsjbAZWHCShRKIDo_JPpL6cyY54cel4V5tmeeeVH4_L_Mi_vhtVopIGMhm-_3TrcxBjE0F7GiG9BFtcbpdUueJBu1DqPRtEyKRvNFhxvsVNl5-HL_ysLBqAS31ic9w43mtTJeHOO8YrOuoIeWVEscgostetfEWyrhcLKHsxhVm5C5SAA2OJ-3Akux0kmA6sfUbHiJ1Vk39s8T0ZzR__A==\" rel=\"nofollow\" target=\"_blank\"><u>investors@silopharma.com<\/u><\/a><\/p>\n<hr \/>\n<p>\n        <sup>1<\/sup> Persistence Market Research, August 2025<\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTcxNTA5OSM3NTg5MDQxIzUwMDA2OTMzOQ==\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/Yzk5Y2JmMjctNmY5Zi00ZDBjLWJhZWEtYWRhZjY2MTk5OGZlLTUwMDA2OTMzOS0yMDI2LTA1LTA3LWVu\/tiny\/Silo-Pharma-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>New initiative from Silo Pharma designed to align with federal actions to accelerate mental health innovation using psychedelic medicines Silo Pharma targets unmet need in a drug market with no FDA-approved therapies that address structural or regenerative aspects of traumatic brain injury Traumatic brain injury therapeutics market estimated to reach\u00a0$6 billion by 2032 SARASOTA, FLA., May 07, 2026 (GLOBE NEWSWIRE) &#8212; Silo Pharma (Nasdaq: SILO) (\u201cSilo\u201d or \u201cthe Company\u201d), a developmental-stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced a strategic initiative to explore ibogaine-based therapeutics for the treatment of traumatic brain injury (TBI) and associated neuropsychiatric conditions. Silo has filed a provisional patent application with the United States Patent and Trademark Office (USPTO) titled \u201cCompositions &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Silo Pharma Files Provisional Patent for Ibogaine-Based Therapeutic Targeting Traumatic Brain Injury&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-959759","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Silo Pharma Files Provisional Patent for Ibogaine-Based Therapeutic Targeting Traumatic Brain Injury - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Silo Pharma Files Provisional Patent for Ibogaine-Based Therapeutic Targeting Traumatic Brain Injury - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"New initiative from Silo Pharma designed to align with federal actions to accelerate mental health innovation using psychedelic medicines Silo Pharma targets unmet need in a drug market with no FDA-approved therapies that address structural or regenerative aspects of traumatic brain injury Traumatic brain injury therapeutics market estimated to reach\u00a0$6 billion by 2032 SARASOTA, FLA., May 07, 2026 (GLOBE NEWSWIRE) &#8212; Silo Pharma (Nasdaq: SILO) (\u201cSilo\u201d or \u201cthe Company\u201d), a developmental-stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced a strategic initiative to explore ibogaine-based therapeutics for the treatment of traumatic brain injury (TBI) and associated neuropsychiatric conditions. Silo has filed a provisional patent application with the United States Patent and Trademark Office (USPTO) titled \u201cCompositions &hellip; Continue reading &quot;Silo Pharma Files Provisional Patent for Ibogaine-Based Therapeutic Targeting Traumatic Brain Injury&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-07T12:22:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTcxNTA5OSM3NTg5MDQxIzUwMDA2OTMzOQ==\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Silo Pharma Files Provisional Patent for Ibogaine-Based Therapeutic Targeting Traumatic Brain Injury\",\"datePublished\":\"2026-05-07T12:22:50+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\\\/\"},\"wordCount\":836,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTcxNTA5OSM3NTg5MDQxIzUwMDA2OTMzOQ==\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/silo-pharma-files-provisional-patent-for-ibogaine-based-therapeutic-targeting-traumatic-brain-injury\\\/\",\"name\":\"Silo Pharma Files Provisional Patent for Ibogaine-Based Therapeutic Targeting Traumatic Brain Injury - 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