{"id":955265,"date":"2026-04-28T07:34:34","date_gmt":"2026-04-28T11:34:34","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/plus-therapeutics-secures-blue-shield-of-california-coverage-for-cnside-cerebrospinal-fluid-assay-for-metastatic-cns-cancer\/"},"modified":"2026-04-28T07:34:34","modified_gmt":"2026-04-28T11:34:34","slug":"plus-therapeutics-secures-blue-shield-of-california-coverage-for-cnside-cerebrospinal-fluid-assay-for-metastatic-cns-cancer","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/plus-therapeutics-secures-blue-shield-of-california-coverage-for-cnside-cerebrospinal-fluid-assay-for-metastatic-cns-cancer\/","title":{"rendered":"Plus Therapeutics Secures Blue Shield of California Coverage for CNSide\u00ae Cerebrospinal Fluid Assay for Metastatic CNS Cancer"},"content":{"rendered":"

\nExpands access by 6 million covered lives, advancing commercial momentum for CNSide\u00ae in metastatic CNS cancers
\n<\/h2>\n
\n

HOUSTON, April 28, 2026 (GLOBE NEWSWIRE) — CNSide Diagnostics, LLC, a wholly-owned subsidiary of Plus Therapeutics, Inc.<\/a>\u00a0(Nasdaq:\u00a0PSTV<\/a>) (\u201cPlus\u201d or the \u201cCompany\u201d), announced today a new payer coverage agreement with Blue Shield of California, effective\u00a0April 2026, providing reimbursement for its CNSide\u00ae Cerebrospinal Fluid (CSF) Tumor Cell Enumeration (TCE) assay for patients with metastatic central nervous system cancers. Blue Shield of California joins a growing list of national and regional payers, including United Healthcare, Humana, and Highmark, that provide coverage for CNSide.<\/p>\n

The addition of Blue Shield of California expands CNSide\u2019s total covered lives from approximately 75 million to 81 million, representing continued progress toward the Company\u2019s 2026 objective of 150 million covered lives, while expanding patient access across the U.S. The agreement is expected to further accelerate adoption of CNSide across oncology centers by reducing reimbursement barriers.<\/p>\n

\u201cThis agreement with Blue Shield of California represents another important step in expanding payer coverage and access to CNSide for patients with leptomeningeal metastases,\u201d said Russ Havranek, EVP Corporate and Commercial Strategy at Plus Therapeutics. \u201cWe continue to execute on our strategy to broaden reimbursement, support physician adoption, and improve outcomes for patients with difficult-to-diagnose CNS cancers.\u201d<\/p>\n

The CNSide\u00ae CSF Assay Platform enables earlier, and more accurate detection and monitoring of leptomeningeal metastases compared to conventional CSF cytology, supporting rapid diagnosis, treatment monitoring, and treatment guidance. The superior clinical utility of CNSide\u00ae over standard of care has been demonstrated in nine peer-reviewed publications, the FORESEE clinical trial, and demonstrated in real-world practice. Earlier detection enabled by CNSide has been shown in health economic analyses to reduce overall leptomeningeal metastases-related healthcare costs by ~40%, driven by earlier detection and treatment optimization.<\/p>\n

Since its commercial launch, more than 11,000 CNSide tests have been performed at over 120 U.S. cancer institutions since 2020, delivering high sensitivity (92%) and specificity (95%), while influencing treatment decisions in 90% of cases.<\/p>\n

This test is available exclusively through CNSide Diagnostics, LLC. as a testing service provided to health care professionals in the U.S.<\/p>\n

\n About CNSide Diagnostics, LLC\u00a0<\/strong>
\n
CNSide Diagnostics, LLC is a wholly owned subsidiary of Plus Therapeutics, Inc. that develops and commercializes proprietary laboratory-developed tests, such as CNSide\u00ae, designed to identify tumor cells that have metastasized to the central nervous system in patients with carcinomas and melanomas. The CNSide\u00ae\u00a0CSF Assay Platform enables quantitative analysis of the cerebrospinal fluid that informs and improves the management of patients with leptomeningeal metastases.\u00a0\u00a0 For more information, visit https:\/\/www.cnside-dx.com\/<\/a>.<\/p>\n

\n About Plus Therapeutics<\/strong>
\n
Headquartered in Houston, Texas, Plus Therapeutics, Inc. is a clinical-stage pharmaceutical company developing targeted radiotherapeutics for difficult-to-treat cancers of the central nervous system with the potential to enhance clinical outcomes. Combining image-guided local beta radiation and targeted drug delivery approaches, the Company is advancing a pipeline of product candidates with lead programs in leptomeningeal metastases (LM) and recurrent glioblastoma (GBM). The Company has built a supply chain through strategic partnerships that enable the development, manufacturing, and future potential commercialization of its products. For more information, visit https:\/\/www.plustherapeutics.com<\/a>.<\/p>\n

\n About Blue Shield of California
<\/strong>Blue Shield of California strives to create a healthcare system worthy of its family and friends that is sustainably affordable. The health plan is a\u00a0taxpaying, nonprofit, independent member of the Blue Shield Association with\u00a06 million members, over 6,500 employees and more than\u00a0$27 billion\u00a0in annual revenue. Founded in 1939 in San Francisco and now headquartered in Oakland, Blue Shield of California and its affiliates provide health, dental, vision,\u00a0Medicaid\u00a0and Medicare healthcare service plans in California. The company has contributed more than $60 million to the Blue Shield of California Foundation in the last three years to have an impact on California communities. For more news about Blue\u00a0Shield of\u00a0California, please visit\u00a0news.blueshieldca.com<\/a>.\u00a0<\/p>\n

\n Forward-Looking Statements<\/strong>
\n
This press release contains statements that may be deemed \u201cforward-looking statements\u201d within the meaning of U.S. securities laws, including statements regarding clinical trials, expected operations and upcoming developments. All statements in this press release other than statements of historical fact are forward-looking statements. These forward-looking statements may be identified by future verbs, as well as terms such as \u201cexpect,\u201d \u201cpotential,\u201d \u201canticipating,\u201d \u201cplanning\u201d and similar expressions or the negatives thereof. Such statements are based upon certain assumptions and assessments made by management in light of their experience and their perception of historical trends, current conditions, expected future developments and other factors they believe to be appropriate.\u00a0\u00a0 These statements include, without limitation, statements regarding the potential market for the CNSide CSF Assay, the timing in which the CNSide CSF Assay is commercially launched and commercialization is expanded, revenue and corporate profitability expectations including support reimbursements and payments for the CNSide CSF Assay, the development and utility of the CNSide CSF Assay and expectations as to the Company\u2019s future performance, including the next steps in developing the Company\u2019s product candidates.<\/p>\n

\n Investor Contact<\/strong>
\n
CORE IR
investor@plustherapeutics.com<\/p>\n

\"\"
\n
\n \"\"\n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

Expands access by 6 million covered lives, advancing commercial momentum for CNSide\u00ae in metastatic CNS cancers HOUSTON, April 28, 2026 (GLOBE NEWSWIRE) — CNSide Diagnostics, LLC, a wholly-owned subsidiary of Plus Therapeutics, Inc.\u00a0(Nasdaq:\u00a0PSTV) (\u201cPlus\u201d or the \u201cCompany\u201d), announced today a new payer coverage agreement with Blue Shield of California, effective\u00a0April 2026, providing reimbursement for its CNSide\u00ae Cerebrospinal Fluid (CSF) Tumor Cell Enumeration (TCE) assay for patients with metastatic central nervous system cancers. Blue Shield of California joins a growing list of national and regional payers, including United Healthcare, Humana, and Highmark, that provide coverage for CNSide. The addition of Blue Shield of California expands CNSide\u2019s total covered lives from approximately 75 million to 81 million, representing continued progress toward the … <\/p>\n

Continue reading “Plus Therapeutics Secures Blue Shield of California Coverage for CNSide\u00ae Cerebrospinal Fluid Assay for Metastatic CNS Cancer”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-955265","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nPlus Therapeutics Secures Blue Shield of California Coverage for CNSide\u00ae Cerebrospinal Fluid Assay for Metastatic CNS Cancer - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/plus-therapeutics-secures-blue-shield-of-california-coverage-for-cnside-cerebrospinal-fluid-assay-for-metastatic-cns-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Plus Therapeutics Secures Blue Shield of California Coverage for CNSide\u00ae Cerebrospinal Fluid Assay for Metastatic CNS Cancer - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Expands access by 6 million covered lives, advancing commercial momentum for CNSide\u00ae in metastatic CNS cancers HOUSTON, April 28, 2026 (GLOBE NEWSWIRE) — CNSide Diagnostics, LLC, a wholly-owned subsidiary of Plus Therapeutics, Inc.\u00a0(Nasdaq:\u00a0PSTV) (\u201cPlus\u201d or the \u201cCompany\u201d), announced today a new payer coverage agreement with Blue Shield of California, effective\u00a0April 2026, providing reimbursement for its CNSide\u00ae Cerebrospinal Fluid (CSF) Tumor Cell Enumeration (TCE) assay for patients with metastatic central nervous system cancers. 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Blue Shield of California joins a growing list of national and regional payers, including United Healthcare, Humana, and Highmark, that provide coverage for CNSide. 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