{"id":953422,"date":"2026-04-21T10:34:09","date_gmt":"2026-04-21T14:34:09","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/"},"modified":"2026-04-21T10:34:09","modified_gmt":"2026-04-21T14:34:09","slug":"bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/","title":{"rendered":"Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting<\/b><\/p>\n<p>CAMBRIDGE, England &amp; BOSTON&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nBicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle<sup>\u00ae<\/sup>) technology, today announced an oral presentation and multiple poster presentations across five abstracts at the American Society of Clinical Oncology (ASCO) 2026 Annual Meeting, taking place May 29\u2013June 2 in Chicago.<\/p>\n<p><b>Presentation Details:<\/b><\/p>\n<p><b>Title<\/b>: Interim analysis results from Duravelo-2: Zelenectide pevedotin (zele; BT8009) + pembrolizumab in patients (pts) with previously untreated locally advanced\/metastatic urothelial carcinoma (la\/mUC)<br \/>\n<br \/><b>Type<\/b>: Rapid Oral Abstract Session<br \/>\n<br \/><b>Session:<\/b> Genitourinary Cancer \u2013 Kidney and Bladder<br \/>\n<br \/><b>Date and Time<\/b>: Monday, June 1, 8:30-8:36 a.m. CT<br \/>\n<br \/><b>Abstract Number<\/b>: 4516<br \/>\n<br \/><b>Lead Author<\/b>: Yohann Loriot, M.D., Institute Gustave Roussy<\/p>\n<p><b>Title<\/b>: Interim analysis results from Duravelo-2: zelenectide pevedotin (zele; BT8009) in patients (pts) with previously treated locally advanced\/metastatic urothelial carcinoma (la\/mUC)<br \/>\n<br \/><b>Type<\/b>: Poster Session<br \/>\n<br \/><b>Session: <\/b>Genitourinary Cancer \u2013 Kidney and Bladder<br \/>\n<br \/><b>Date and Time<\/b>: Sunday, May 31, 9 a.m.-12 p.m. CT<br \/>\n<br \/><b>Abstract Number<\/b>: 4566<br \/>\n<br \/><b>Lead Author<\/b>: Dan Petrylak, M.D., Yale School of Medicine<\/p>\n<p><b>Title<\/b>: Zelenectide pevedotin (BT8009) monotherapy in previously treated metastatic urothelial carcinoma (mUC): Update on Duravelo-1<br \/>\n<br \/><b>Type<\/b>: Poster Session<br \/>\n<br \/><b>Session: <\/b>Genitourinary Cancer \u2013 Kidney and Bladder<br \/>\n<br \/><b>Date and Time<\/b>: Sunday, May 31, 9 a.m.-12 p.m. CT<br \/>\n<br \/><b>Abstract Number<\/b>: 4563<br \/>\n<br \/><b>Lead Author<\/b>: Oscar Reig Torras, M.D., Hospital Cl\u00ednic de Barcelona<\/p>\n<p><b>Title<\/b>: Zelenectide pevedotin (BT8009) plus pembrolizumab in 1L cisplatin-ineligible locally advanced\/metastatic urothelial carcinoma: Update on Duravelo-1 B7<br \/>\n<br \/><b>Type<\/b>: Poster Session<br \/>\n<br \/><b>Session: <\/b>Genitourinary Cancer \u2013 Kidney and Bladder<br \/>\n<br \/><b>Date and Time<\/b>: Sunday, May 31, 9 a.m.-12 p.m. CT<br \/>\n<br \/><b>Abstract Number<\/b>: 4564<br \/>\n<br \/><b>Lead Author<\/b>: Ignacio Duran, M.D., Hospital Universitario Marqu\u00e9s de Valdecilla<\/p>\n<p><b>Title<\/b>: Identify optimized dosage for zelenectide pevedotin in locally advanced\/metastatic urothelial carcinoma (la\/mUC) using quantitative analyses<br \/>\n<br \/><b>Type<\/b>: Poster Session<br \/>\n<br \/><b>Session: <\/b>Genitourinary Cancer \u2013 Kidney and Bladder<br \/>\n<br \/><b>Date and Time<\/b>: Sunday, May 31, 9 a.m.-12 p.m. CT<br \/>\n<br \/><b>Abstract Number<\/b>: 4567<br \/>\n<br \/><b>Lead Author<\/b>: Yasong Lu, Ph.D., Bicycle Therapeutics<\/p>\n<p>\nThe presentations will be made available in the Publications section of the Bicycle Therapeutics website on the morning of each session.<\/p>\n<p><b>About Bicycle Therapeutics<\/b><\/p>\n<p>\nBicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle<sup>\u00ae<\/sup> molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating nuzefatide pevedotin, formerly BT5528, a Bicycle<sup>\u00ae<\/sup> Drug Conjugate (BDC<sup>\u00ae<\/sup>) targeting EphA2, a historically undruggable target; a pipeline of other bicycle-based conjugate molecules, including Bicycle<sup>\u00ae<\/sup> Radioconjugates (BRC<sup>\u00ae<\/sup>) for radiopharmaceutical use; zelenectide pevedotin (formerly BT8009), a BDC<sup>\u00ae<\/sup> targeting Nectin-4, a well-validated tumor antigen; BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist<sup>\u00ae<\/sup> (Bicycle TICA<sup>\u00ae<\/sup>) targeting Nectin-4 and agonizing CD137; and, through various partnerships, is exploring the use of Bicycle<sup>\u00ae<\/sup> technology to develop therapies for diseases in additional therapeutic areas.<\/p>\n<p>\nBicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Lexington, Mass. For more information, visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fbicycletherapeutics.com%2F&amp;esheet=54519269&amp;newsitemid=20260420659430&amp;lan=en-US&amp;anchor=bicycletherapeutics.com&amp;index=1&amp;md5=407505d01516b0e138fa4eb9330959ac\">bicycletherapeutics.com<\/a>.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260420659430r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20260420659430\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20260420659430\/en\/<\/a><\/span><\/p>\n<p><b>Investors:<br \/>\n<\/b><br \/>Matthew DeYoung<br \/>\n<br \/>Argot Partners<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:ir@bicycletx.com\">ir@bicycletx.com<br \/>\n<\/a><br \/>212-600-1902<\/p>\n<p><b>Media:<br \/>\n<\/b><br \/>Argot Partners<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:media@bicycletx.com\">media@bicycletx.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> Illinois Massachusetts Europe United States United Kingdom North America<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Biotechnology Health Pharmaceutical Clinical Trials Oncology<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\" \/>\n","protected":false},"excerpt":{"rendered":"<p>Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting CAMBRIDGE, England &amp; BOSTON&#8211;(BUSINESS WIRE)&#8211; Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle\u00ae) technology, today announced an oral presentation and multiple poster presentations across five abstracts at the American Society of Clinical Oncology (ASCO) 2026 Annual Meeting, taking place May 29\u2013June 2 in Chicago. Presentation Details: Title: Interim analysis results from Duravelo-2: Zelenectide pevedotin (zele; BT8009) + pembrolizumab in patients (pts) with previously untreated locally advanced\/metastatic urothelial carcinoma (la\/mUC) Type: Rapid Oral Abstract Session Session: Genitourinary Cancer \u2013 Kidney and Bladder Date and Time: Monday, June 1, 8:30-8:36 a.m. CT Abstract Number: &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-953422","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting CAMBRIDGE, England &amp; BOSTON&#8211;(BUSINESS WIRE)&#8211; Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle\u00ae) technology, today announced an oral presentation and multiple poster presentations across five abstracts at the American Society of Clinical Oncology (ASCO) 2026 Annual Meeting, taking place May 29\u2013June 2 in Chicago. Presentation Details: Title: Interim analysis results from Duravelo-2: Zelenectide pevedotin (zele; BT8009) + pembrolizumab in patients (pts) with previously untreated locally advanced\/metastatic urothelial carcinoma (la\/mUC) Type: Rapid Oral Abstract Session Session: Genitourinary Cancer \u2013 Kidney and Bladder Date and Time: Monday, June 1, 8:30-8:36 a.m. CT Abstract Number: &hellip; Continue reading &quot;Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-04-21T14:34:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260420659430r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting\",\"datePublished\":\"2026-04-21T14:34:09+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\\\/\"},\"wordCount\":587,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20260420659430r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\\\/\",\"name\":\"Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting - 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Presentation Details: Title: Interim analysis results from Duravelo-2: Zelenectide pevedotin (zele; BT8009) + pembrolizumab in patients (pts) with previously untreated locally advanced\/metastatic urothelial carcinoma (la\/mUC) Type: Rapid Oral Abstract Session Session: Genitourinary Cancer \u2013 Kidney and Bladder Date and Time: Monday, June 1, 8:30-8:36 a.m. CT Abstract Number: &hellip; Continue reading \"Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/","og_site_name":"Market Newsdesk","article_published_time":"2026-04-21T14:34:09+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260420659430r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting","datePublished":"2026-04-21T14:34:09+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/"},"wordCount":587,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260420659430r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/bicycle-therapeutics-announces-oral-and-poster-presentations-at-the-2026-asco-annual-meeting\/","name":"Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting - 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