{"id":953006,"date":"2026-04-20T16:09:18","date_gmt":"2026-04-20T20:09:18","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/"},"modified":"2026-04-20T16:09:18","modified_gmt":"2026-04-20T20:09:18","slug":"spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/","title":{"rendered":"Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants"},"content":{"rendered":"<p>        <!--body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p><b>Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants<\/b><\/p>\n<p>SOUTH SAN FRANCISCO, Calif.&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nSpruce Biosciences, Inc. (\u201cSpruce Biosciences\u201d) (NASDAQ: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders with significant unmet medical need, today announced that it has commenced an underwritten public offering of shares of its common stock or pre-funded warrants to purchase shares of its common stock in lieu thereof. All of the securities are being offered by Spruce Biosciences. In addition, Spruce Biosciences expects to grant the underwriters a 30-day option to purchase additional shares of its common stock in an amount of up to 15% of the aggregate number of shares sold in the offering at the public offering price, less underwriting discounts and commissions. The proposed offering is subject to market and other conditions, and there can be no assurance as to whether or when the proposed offering may be completed, or as to the actual size or terms of the proposed offering.<\/p>\n<p>\nLeerink Partners, Guggenheim Securities, and Oppenheimer &amp; Co. are acting as joint book-running managers and Jones and Craig-Hallum are acting as co-managers for the proposed offering.<\/p>\n<p>\nThe shares of common stock and pre-funded warrants are being offered by Spruce Biosciences pursuant to a shelf registration statement on Form S-3, including a base prospectus, that was filed with the Securities and Exchange Commission (the \u201cSEC\u201d) on October 29, 2025 and subsequently declared effective by the SEC on November 26, 2025. The proposed offering is being made only by means of a prospectus supplement and the accompanying prospectus that will form a part of the registration statement. A preliminary prospectus supplement and the accompanying prospectus relating to the proposed offering will be filed with the SEC and will be available on the SEC\u2019s website at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.sec.gov&amp;esheet=54518989&amp;newsitemid=20260420930919&amp;lan=en-US&amp;anchor=www.sec.gov&amp;index=1&amp;md5=2c06015e3a9a62ef9ec4ce4f9a82c463\">www.sec.gov<\/a>. Copies of the preliminary prospectus supplement and the accompanying prospectus, when available, may also be obtained from: Leerink Partners LLC, Attention: Syndicate Department, 53 State Street, 40<sup>th<\/sup> Floor, Boston, MA 02109, by telephone at (800) 808-7525, ext. 6105 or by email at <a rel=\"nofollow\" href=\"mailto:syndicate@leerink.com\">syndicate@leerink.com<\/a>; Guggenheim Securities, LLC, Attention: Equity Syndicate Department, 330 Madison Avenue, 8<sup>th<\/sup> Floor, New York, NY 10017, by telephone at (212) 518-9544 or by email at <a rel=\"nofollow\" href=\"mailto:GSEquityProspectusDelivery@guggenheimpartners.com\">GSEquityProspectusDelivery@guggenheimpartners.com<\/a>; or Oppenheimer &amp; Co. Inc., Attention: Syndicate Prospectus Department, 85 Broad Street, 26<sup>th<\/sup> Floor, New York, NY 10004, or by telephone at (212) 667-8055 or by email at <a rel=\"nofollow\" href=\"mailto:EquityProspectus@opco.com\">EquityProspectus@opco.com<\/a>. The final terms of the proposed offering will be disclosed in a final prospectus supplement to be filed with the SEC.<\/p>\n<p>\nThis press release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of these securities in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.<\/p>\n<p><b>About Spruce Biosciences<\/b><\/p>\n<p>\nSpruce Biosciences, Inc. (Nasdaq: SPRB) is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders with significant unmet medical need.<\/p>\n<p><b>Forward-Looking Statements<\/b><\/p>\n<p>\nThis press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. In some cases, you can identify forward-looking statements by terminology such as \u201caim,\u201d \u201canticipate,\u201d \u201cassume,\u201d \u201cbelieve,\u201d \u201ccontemplate,\u201d \u201ccontinue,\u201d \u201ccould,\u201d \u201cdesign,\u201d \u201cdue,\u201d \u201cestimate,\u201d \u201cexpect,\u201d \u201cgoal,\u201d \u201cintend,\u201d \u201cmay,\u201d \u201cobjective,\u201d \u201cplan,\u201d \u201cpositioned,\u201d \u201cpotential,\u201d \u201cpredict,\u201d \u201cproposed,\u201d \u201cseek,\u201d \u201cshould,\u201d \u201csuggest,\u201d \u201ctarget,\u201d \u201con track,\u201d \u201cwill,\u201d \u201cwould\u201d and other similar expressions that are predictions of or indicate future events and future trends, or the negative of these terms or other comparable terminology. All statements other than statements of historical facts contained in this press release are forward-looking statements. These forward-looking statements include, but are not limited to, statements about Spruce Biosciences\u2019 proposed public offering and Spruce Biosciences\u2019 intention to grant the underwriters an option to purchase additional shares. Forward-looking statements are not guarantees of future performance and are subject to risks and uncertainties that could cause actual results and events to differ materially from those anticipated, including, but not limited to, risks and uncertainties related to, among other things, market conditions and the demand for Spruce Biosciences\u2019 securities. These and other risks are described in greater detail under the section titled \u201cRisk Factors\u201d contained in the preliminary prospectus supplement and the accompanying prospectus, the company\u2019s Annual Report on Form 10-K for the year ended December 31, 2025 and the company\u2019s other filings with the SEC. Any forward-looking statements that the company makes in this press release are made pursuant to the Private Securities Litigation Reform Act of 1995, as amended, and speak only as of the date of this press release. Except as required by law, the company undertakes no obligation to publicly update any forward-looking statements, whether as a result of new information, future events or otherwise.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260420930919r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20260420930919\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20260420930919\/en\/<\/a><\/span><\/p>\n<p><b>Investor Contact:<\/b><\/p>\n<p>\nMonique Kosse<br \/>\n<br \/>Gilmartin Group<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:Monique@GilmartinIR.com\">Monique@GilmartinIR.com<br \/>\n<\/a><br \/><a rel=\"nofollow\" href=\"mailto:investors@sprucebio.com\">investors@sprucebio.com<\/a><\/p>\n<p><b>Media Contact:<\/b><\/p>\n<p>\nCarolyn Hawley<br \/>\n<br \/>Inizio Evoke Comms<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:Carolyn.Hawley@inizioevoke.com\">Carolyn.Hawley@inizioevoke.com<br \/>\n<\/a><br \/><a rel=\"nofollow\" href=\"mailto:media@sprucebio.com\">media@sprucebio.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> California United States North America<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Biotechnology Pharmaceutical Health<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20260420930919\/en\/2685951\/3\/SB_Logo_Short_Color_Large.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants SOUTH SAN FRANCISCO, Calif.&#8211;(BUSINESS WIRE)&#8211; Spruce Biosciences, Inc. (\u201cSpruce Biosciences\u201d) (NASDAQ: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders with significant unmet medical need, today announced that it has commenced an underwritten public offering of shares of its common stock or pre-funded warrants to purchase shares of its common stock in lieu thereof. All of the securities are being offered by Spruce Biosciences. In addition, Spruce Biosciences expects to grant the underwriters a 30-day option to purchase additional shares of its common stock in an amount of up to 15% of the aggregate number of shares sold in the offering at &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-953006","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants SOUTH SAN FRANCISCO, Calif.&#8211;(BUSINESS WIRE)&#8211; Spruce Biosciences, Inc. (\u201cSpruce Biosciences\u201d) (NASDAQ: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders with significant unmet medical need, today announced that it has commenced an underwritten public offering of shares of its common stock or pre-funded warrants to purchase shares of its common stock in lieu thereof. All of the securities are being offered by Spruce Biosciences. In addition, Spruce Biosciences expects to grant the underwriters a 30-day option to purchase additional shares of its common stock in an amount of up to 15% of the aggregate number of shares sold in the offering at &hellip; Continue reading &quot;Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-04-20T20:09:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260420930919r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants\",\"datePublished\":\"2026-04-20T20:09:18+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\\\/\"},\"wordCount\":870,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20260420930919r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\\\/\",\"name\":\"Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants - 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(\u201cSpruce Biosciences\u201d) (NASDAQ: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders with significant unmet medical need, today announced that it has commenced an underwritten public offering of shares of its common stock or pre-funded warrants to purchase shares of its common stock in lieu thereof. All of the securities are being offered by Spruce Biosciences. In addition, Spruce Biosciences expects to grant the underwriters a 30-day option to purchase additional shares of its common stock in an amount of up to 15% of the aggregate number of shares sold in the offering at &hellip; Continue reading \"Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/","og_site_name":"Market Newsdesk","article_published_time":"2026-04-20T20:09:18+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260420930919r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants","datePublished":"2026-04-20T20:09:18+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/"},"wordCount":870,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20260420930919r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/spruce-biosciences-announces-proposed-public-offering-of-common-stock-and-pre-funded-warrants\/","name":"Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants - 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