{"id":952822,"date":"2026-04-20T08:07:16","date_gmt":"2026-04-20T12:07:16","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\/"},"modified":"2026-04-20T08:07:16","modified_gmt":"2026-04-20T12:07:16","slug":"amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\/","title":{"rendered":"Amneal Announces Additional Positive Interim Phase 4 ELEVATE-PD Results with CREXONT\u00ae for Parkinson\u2019s Disease, Including Over 3 More Hours of Daily \u201cGood On\u201d Time When Switching from RYTARY\u00ae"},"content":{"rendered":"<div class=\"mw_release\">\n<ul>\n<li style=\"text-align:left\">Phase 4 ELEVATE-PD interim data (n=111) demonstrated clinically meaningful, consistent benefits of CREXONT across all prior treatment groups<\/li>\n<li style=\"text-align:left\">Demonstrated substantial increases in daily \u201cGood On\u201d time, reductions in \u201cOff\u201d time, and meaningful improvements in motor function after switching to CREXONT<sup>\u00ae<\/sup><\/li>\n<li style=\"text-align:left\">Patients switching to CREXONT<sup>\u00ae<\/sup> from RYTARY<sup>\u00ae<\/sup> gained 3.07 hours of additional daily \u201cGood On\u201d time and nearly doubled the duration of continuous \u201cGood On\u201d intervals, enabling longer, uninterrupted periods of effective symptom control\n<\/li>\n<\/ul>\n<p align=\"left\">BRIDGEWATER, N.J., April  20, 2026  (GLOBE NEWSWIRE) &#8212; Amneal Pharmaceuticals, Inc. (Nasdaq: AMRX) (\u201cAmneal\u201d or the \u201cCompany\u201d), today announced new positive interim results from its ongoing Phase 4 ELEVATE-PD study, presented at the 2026 American Academy of Neurology (AAN).<\/p>\n<p align=\"left\">The first 111 patients evaluated after six weeks of treatment demonstrated substantial clinical benefit after switching to CREXONT<sup>\u00ae<\/sup> (carbidopa and levodopa) extended-release capsules, regardless of whether patients switched from immediate-release carbidopa\/levodopa (IR CD\/LD), IR CD\/LD plus a COMT inhibitor, or RYTARY<sup>\u00ae<\/sup> (carbidopa and levodopa) extended-release capsules. These interim findings build on the established efficacy and safety profile of CREXONT demonstrated in the Phase 3 RISE-PD trial and reflected in the FDA-approved prescribing information.<\/p>\n<p align=\"left\">After patients switched from prior therapies, treatment with CREXONT delivered meaningful increases in \u201cGood On\u201d time, reductions in \u201cOff\u201d time, and improved motor symptom control. Patients switching from RYTARY achieved consistent gains in continuous \u201cGood On\u201d intervals \u2013 the length of uninterrupted time patients spend feeling their best. The most common adverse events (\u22653%) in the study were dizziness (9.0%), nausea (7.2%), falls (7.2%), dyskinesia\u00a0(4.5%), hallucination (3.6%), and headache (3.6%).\u00a0<\/p>\n<p align=\"left\">\u201cIn the absence of a cure for Parkinson\u2019s, our goal as clinicians is to help patients better manage their symptoms and preserve quality of life for as long as possible,\u201d said Dr. Robert Hauser, MD, a study investigator and Professor of Neurology at the Parkinson\u2019s Disease and Movement Disorders Center, University of South Florida. \u201cThese encouraging interim results underscore the real-world impact CREXONT can have in giving patients more \u2018Good On\u2019 time with fewer dosing interruptions throughout their day-to-day.\u201d<\/p>\n<p align=\"left\">\u201cWhen we assess what patients value most in their Parkinson\u2019s disease treatment, longer periods of \u2018Good On\u2019 time and less burdensome dosing schedules are among the most important priorities,\u201d said Dr. Avinash Desai, Senior Vice President and Chief Scientific Officer, Specialty, at Amneal. \u201cThese interim results confirm that CREXONT delivers on that need, giving patients more \u2018Good On\u2019 time, reducing motor fluctuations, and providing the kind of consistent, predictable symptom control that can make a real difference in daily life.\u201d<\/p>\n<p align=\"left\">\n        <strong>Overall Interim Findings (First 111 Patients, Six-Week Analysis)<\/strong><br \/>\n        <br \/>Among 111 patients who switched to CREXONT (mean age 67.3\u00b19.58 years):<\/p>\n<p align=\"left\">\n        <strong>Increased Daily \u201cGood On\u201d Time:<\/strong>\n      <\/p>\n<ul>\n<li>+3.40 hours when switching from IR CD\/LD (n=74)<\/li>\n<li>+2.91 hours when switching from IR CD\/LD + COMT inhibitor (n=9)<\/li>\n<li>+3.07 hours when switching from RYTARY (n=22)\n<\/li>\n<\/ul>\n<p align=\"left\">\n        <strong>Reduced Daily \u201cOff\u201d Time:<\/strong>\n      <\/p>\n<ul>\n<li>\u20133.18 hours when switching from IR CD\/LD<\/li>\n<li>\u20133.09 hours when switching from IR CD\/LD + COMT inhibitor<\/li>\n<li>\u20132.90 hours when switching from RYTARY\n<\/li>\n<\/ul>\n<p align=\"left\">\n        <strong>Improved MDS-UPDRS Total Scores<\/strong>\n      <\/p>\n<ul>\n<li>Improvements of \u201315.3, \u201310.0, and \u201310.3 points when switching from IR CD\/LD, IR CD\/LD + COMT inhibitor, and RYTARY, respectively \u2014 reductions of this magnitude reflect clinically meaningful gains in overall motor function\n<\/li>\n<\/ul>\n<p align=\"left\">\n        <strong>Subgroup Analysis: Additional Interim Findings in Patients Switching from RYTARY<sup>\u00ae<\/sup><\/strong><br \/>\n        <br \/>Among the 22 patients switching from RYTARY, CREXONT delivered particularly notable gains in symptom control:<\/p>\n<ul>\n<li>Mean duration of continuous \u201cGood On\u201d intervals nearly doubled, increasing from 3.45 hours at baseline to 6.58 hours at Week 6, a 3.09-hour gain in uninterrupted symptom control<\/li>\n<li>Mean daily motor fluctuations were meaningfully reduced, decreasing from 4.75 at baseline to 2.79 at Week 6, a 1.92 reduction in daily motor fluctuations\n<\/li>\n<\/ul>\n<p align=\"left\">\n        <strong>Safety: <\/strong>In the study, treatment-emergent adverse events (TEAEs) were generally mild to moderate and consistent with prior therapy. The most common (\u22653%) in the study were dizziness (9.0%), nausea (7.2%), falls (7.2%), dyskinesia\u00a0(4.5%), hallucination (3.6%), and headache (3.6%).\u00a0<\/p>\n<p align=\"left\">CREXONT should not be taken with antidepressant medications known as nonselective monoamine oxidase (MAO) inhibitors. CREXONT may cause falling asleep during activities of daily living, somnolence, or dizziness. Treatment with carbidopa\/levodopa, including CREXONT, may contribute to reduced vitamin B6 levels. Seizures associated with vitamin B6 deficiency have been reported. Evaluate vitamin B6 levels before and during treatment with carbidopa\/levodopa therapies.<\/p>\n<p align=\"left\">CREXONT is Amneal\u2019s next-generation extended-release carbidopa\/levodopa (CD\/LD) formulation that uses a novel mucoadhesive polymer designed to optimize levodopa delivery and absorption, providing the longest-lasting levodopa plasma levels of any oral CD\/LD therapy available today.<\/p>\n<p align=\"left\">As ELEVATE-PD continues to enroll, Amneal will present longer-term outcomes and patient-reported results throughout 2026, building a comprehensive body of evidence for CREXONT\u2019s impact on motor symptom control and functional independence for people living with Parkinson\u2019s disease.<\/p>\n<p align=\"left\">\n        <strong>About CREXONT<sup>\u00ae<\/sup><\/strong><br \/>\n        <br \/>CREXONT is an innovative formulation consisting of immediate-release granules with carbidopa and levodopa for rapid onset of action and extended-release pellets containing a mucoadhesive polymer technology with a levodopa core for long-lasting efficacy. CREXONT formulation and dosage strengths are different from <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=B_mDazisI1cDTVlq4T8HKX--Rv2y8v5Adt-nuCPwLlP6abulvZUpPImNCY8Of_H0oGynNTadQ5r7Vq3w_t2exfmgIlNy24rijJJ9c9MT40xfxrI83WQpOvDGlJxQrM8d\" rel=\"nofollow\" target=\"_blank\">RYTARY<sup>\u00ae<\/sup><\/a> (carbidopa and levodopa) extended-release capsules approved by the U.S. FDA in 2015. Learn more about CREXONT at\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=UpaYoWM04idd0ts406pyvwN8ha1LqcS12pKBm_s9geRm_xzvtmJJzyFxI6H6LOEpv6r78WMVNwup5-auspACS5dGrZDMneUMoH8QwoBJMpKaPOWxWUjfuto0zQG2Cza0HiIWLiEnrEYbusr4cWPIe8QB7m9OhHWlWmPpOxLgwNc3qu3yqobZc344wpU0o3o6WK8-tTiDpc7w4y9BI_yg8wifMXxyWIUOw2Eq2usvdyk2RnK56JKEv5_VUTKRmWxQQ9gcXLaiK4SGAE-vZqPaQVRDhy0j3n9b2DpR-zaOxMpO1rdnp9AjMtPDYKhsLSdvZwi63JvWkeYyeEKlrkNN2sD3v81XmqESYsYLejoByeC1WEMfL-rxN63zbSwWznsMAfXlcTe5vRpoge7bSzloEG55ed6S-Qqz7NX_4bdrI36IXqfmBEgasdNdSfLEU-5TA5q89eWLdxouTPP2wcQ_s5ePZd8HGrbavJi0gpkuKjnfuJ_PjLAMIO1tO_RUuYdG977piaHsiS-aDB5-OUpdYDIIJeqKOmplV3yrpI7B6IM=\" rel=\"nofollow\" target=\"_blank\">crexont.com<\/a>.<\/p>\n<p align=\"left\">\n        <strong>About ELEVATE-PD<\/strong><br \/>\n        <br \/>ELEVATE-PD is an open-label, Phase 4, multi-center clinical study designed to evaluate the real-world efficacy and safety of switching to CREXONT in adults with Parkinson\u2019s disease experiencing motor complications such as OFF periods and dyskinesia despite being on a stable dose of an oral levodopa-based regimen. The trial plans to enroll approximately 220 participants and will follow them for 13\u201314 months, consisting of 10 clinical visits.<\/p>\n<p align=\"left\">\n        <strong>INDICATION<\/strong><br \/>\n        <br \/>CREXONT (carbidopa and levodopa) extended-release capsules for oral use is indicated for the treatment of Parkinson\u2019s disease, post-encephalitic parkinsonism, and parkinsonism that may follow carbon monoxide intoxication or manganese intoxication in adults.<\/p>\n<p align=\"left\">\n        <strong>IMPORTANT SAFETY INFORMATION<\/strong>\n      <\/p>\n<ul>\n<li>Do not take CREXONT with antidepressant medications known as nonselective monoamine oxidase (MAO) inhibitors.<\/li>\n<li>Do not take CREXONT with other carbidopa-levodopa preparations without consulting your healthcare provider.<\/li>\n<li>CREXONT may cause falling asleep during activities of daily living, somnolence, or dizziness. Avoid activities that require alertness such as driving and operating machinery, until you know how CREXONT affects you.<\/li>\n<li>Your doctor should evaluate vitamin B6 levels before and during treatment with carbidopa\/levodopa therapies as seizures associated with low levels of vitamin B6 have been reported. Traditional anti-seizure medications were not effective, and seizures were only resolved after vitamin B6 administration.<\/li>\n<li>Other symptoms of vitamin B6 deficiency include depression, confusion, cracked corners of the mouth, swollen tongue, skin inflammation, low red blood cell count, and\/or numbness, tingling, or weakness in the extremities. Your doctor may advise you to take vitamin B6 as necessary.<\/li>\n<li>The most common side effects that may occur with CREXONT are nausea and anxiety.<\/li>\n<li>Avoid sudden discontinuation or rapid dose reduction with CREXONT. If you are discontinuing CREXONT, work with your healthcare provider to taper the dose over time to reduce the risk of fever or confusion.<\/li>\n<li>You may take CREXONT with or without food; but taking it with food may decrease or delay its effect. Consider taking the first dose of the day about 1 to 2 hours before eating.<\/li>\n<li>Swallow CREXONT whole. Do not chew, divide, or crush the capsules.<\/li>\n<li>Do not take CREXONT with alcohol.\n<\/li>\n<\/ul>\n<p align=\"left\">\n        <strong>Tell your healthcare provider if you:<\/strong>\n      <\/p>\n<ul>\n<li>Have any heart conditions, especially if you have had a heart attack or irregular heartbeats.<\/li>\n<li>Experience hallucinations or abnormal thoughts and behaviors.<\/li>\n<li>Have an inability to control urges to gamble, have increased sexual urges, or experience other intense urges.<\/li>\n<li>Have thoughts of suicide or have attempted suicide.<\/li>\n<li>Have abnormal involuntary movements that appear or get worse during treatment.<\/li>\n<li>Have ever had a peptic ulcer or glaucoma.<\/li>\n<li>Become or intend to become pregnant. Based on animal data, CREXONT may cause fetal harm.<\/li>\n<li>Are breastfeeding during therapy.<\/li>\n<li>Have side effects; your doctor can adjust your dose.\n<\/li>\n<\/ul>\n<p align=\"left\">\n        <strong>To report SUSPECTED ADVERSE REACTIONS, contact Amneal Specialty, a division of Amneal Pharmaceuticals LLC at 1-877-835-5472 or the FDA at 1-800-FDA-1088 or\u00a0<\/strong><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=6QwRfJrtwNM-AVt5fb8Azu91-QFTlzfdcEnKco3tfsHU3Xc-g3JLSAZaBwo2rF5ZMjRn7Ghhvz_EOw3SiGMORIedPFLtiLBAA9vaKE8r_oOff9gfTfEmFywHX9ssVwo9X1K3tH5a8QgnTndYQfRulaEBtEzRfBarzSSghJ29b5dpDxeFMpq4XOaRgiYesStNs4mLOpynz59dLrQMf1beOUSJ06xG49jEWqZN_AyQyd8TDIYT9-uZyJnuw_nX7WEr2KPRa89iTdBohG_jgpa3eglSGMG_RierkTB06H-urAJ0aFmXZiJASLFq9Gsbr9aR-swW954BBU-7r67SqblVyfKDfA2BWjobUq8zZ7JvoxLh4v_Ds1Sv_dsxixwDxultKrCKFmT4sr-uhL_ONx71GDOvDZKCgtkFp3donuc8z3JmrvegKITGHCDbahzfeV828OprtXarv6k-TxzxXYycOtyBf64beTUHcAtRGRlDlhVOSEgNIt6X2L37_7fJRY8fHC6Fxq-QgfhvbLun7yS4Lj6BqSCmqBtqEV_fRrVU_9KhRn4T5EecyoYoF73XS2UeNkJspVePYNLSQYAeM6BpdvUvmRaLchbeWD6xAdWzPtw=\" rel=\"nofollow\" target=\"_blank\"><br \/>\n          <strong>www.fda.gov\/medwatch<\/strong><br \/>\n        <\/a><br \/>\n        <strong>.<\/strong>\n      <\/p>\n<p align=\"left\">\n        <strong>Please read the\u00a0<\/strong><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=HT4GXYOwfx5AFzIOeZlHnFddNteomOYiwOIi5RczR80HAdk7Eg85lT3o_mumH9R1A_aGpqeGTJKrxpCvkPtvG6dwjgZylA0HxWlaPT_W4qwwqo-wLsoQuDFiZvGTaMAb-y4F-nR6ev6pvkyexC4XbxiDcnT6Bd4l-Sqq_OCxjc7cgTkwQdSdoO-CYrqqaPiXk5sbYD0DzIn-Kyg1ZwGDOcDs_yOduMHF-bXMcbtfWlvq-bUxW4vtMTsoKJxvfuWZJHzoPlFOFA6E2fgwFjbIbjSBbsnf4T_TU36wyEkTACgTCMaRxABVZbQ8WFQs88-unUxKEXHNhtMWA6LxEqysYWKY9WeB2h_LOvjy7nt47MoQnc3jlgmsuVO7HhMffwUUQc4YmwyPoooQ9yk3WUELSzqkoFOqeyXu9yvcZ3VzzIFCS2IaLneO1oAseoQkhJrBUF5IUpKTaQnIvtfHT0VlvKdKEtiQqrrO7Lb3MVLcC_z1PienAcBpirzY_jqYJNYwGWvENWBkI9BNcEuyFyKqp8ntdnK9jM6pqyi1S1JJfY54WiUDs1bETNb238as1gHWK6VF01L2y1gBe9feT5pTG37fX_rt1A1a5cg2nLKteehN0_5g14gKBGicj1QstL-SwN8RzMcGzroGdJygQqUD3A==\" rel=\"nofollow\" target=\"_blank\"><br \/>\n          <strong>full Prescribing Information<\/strong><br \/>\n        <\/a><br \/>\n        <strong>. For more information talk to your healthcare provider.<\/strong>\n      <\/p>\n<p align=\"left\">\n        <strong>About Parkinson\u2019s Disease<\/strong><br \/>\n        <br \/>Parkinson\u2019s disease (PD) has become the fastest growing neurological disorder worldwide, with approximately 1 million people diagnosed in the U.S.\u00a0It is a progressive disorder of the central nervous system (CNS) that affects dopamine-producing neurons in the brain that affect movement. PD is characterized by slowness of movement, stiffness, resting tremor and impaired balance.\u00a0While PD is not considered a fatal disease, it is associated with significant morbidity and disability.\u00a0The average age at diagnosis for people with PD is 60; as people live longer, the number of people living with PD is predicted to grow significantly over the coming decades.<\/p>\n<p align=\"left\">\n        <strong>About Amneal<\/strong><br \/>\n        <br \/>Amneal Pharmaceuticals, Inc. (Nasdaq: AMRX), headquartered in Bridgewater, New Jersey, is a diversified, global biopharmaceutical leader focused on expanding access to affordable and innovative medicines. Founded in 2002 by brothers and co-CEOs Chirag and Chintu Patel, Amneal was built on the belief that innovation only matters if it\u2019s accessible. Today, Amneal has a diverse and growing portfolio of approximately 300 complex, specialty and biosimilar medicines, delivering over 160 million prescriptions each year, primarily in the United States. Our Affordable Medicines segment spans retail, injectable, and biosimilar products. Our Specialty segment provides branded treatments in neurology, including Parkinson\u2019s disease and migraine, and endocrinology. Our AvKARE segment distributes pharmaceuticals and medical products to U.S. federal, retail, and institutional customers. For more information, visit\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=70PTolmDMOTp4B3rllLoQF1uRdqtPLF1dQxQSYee2dL-ZFVZ4zqxWjBVKW6N1-pM07IL8Ubi254Fqq3O02tlIA==\" rel=\"nofollow\" target=\"_blank\">www.amneal.com<\/a>\u00a0and follow us on LinkedIn.<\/p>\n<p align=\"left\">\n        <strong>Cautionary Statement on Forward-Looking Statements<\/strong><br \/>\n        <br \/>Certain statements contained herein, regarding matters that are not historical facts, may be forward-looking statements (as defined in the U.S. Private Securities Litigation Reform Act of 1995). Such forward-looking statements include statements regarding management\u2019s intentions, plans, beliefs, expectations, financial results, or forecasts for the future, including among other things: discussions of future operations; expected or estimated operating results and financial performance; and statements regarding our positioning, including our ability to drive sustainable long-term growth, and other non-historical statements. Words such as \u201cplans,\u201d \u201cexpects,\u201d \u201cwill,\u201d \u201canticipates,\u201d \u201cestimates,\u201d and similar words, or the negatives thereof, are intended to identify estimates and forward-looking statements. The forward-looking statements contained herein are also subject generally to other risks and uncertainties that are described from time to time in the Company\u2019s filings with the Securities and Exchange Commission, including under Item 1A, \u201cRisk Factors\u201d in the Company\u2019s most recent Annual Report on Form 10-K and in its subsequent reports on Forms 10-Q and 8-K. Forward-looking statements included herein speak only as of the date hereof and we undertake no obligation to revise or update such statements to reflect the occurrence of events or circumstances after the date hereof.<\/p>\n<p align=\"left\">\n        <strong>Investor Contact<\/strong><br \/>\n        <br \/>Anthony DiMeo<br \/>VP, Investor Relations<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=XmrMxJnB_cynryEbmmjnSzx3D4CqcWLcdEidCNvGIbYqQOSwwp64fLZY2P1aPggWIx22CeWBwdRd_SWZ5zMlMyYk2_imwLXYhWlWAvz6_ObGOA-GcOaidNiOS4y9BDa04EfDEESfN8GiOEXb2_hodAmaZU24lpb5ZM8_L2M5q87jHpBZlz-UrH_WROPxsGw5-H0XGblEH8o_fjJG-hXMmJVgJeSBhME_G_ngJVcUqJLPiUMT3pYILBM-6kiVil-YWqdFIv_xvXv3aD3vt77AyooknGyU9HXGoNDJEvsblPA=\" rel=\"nofollow\" target=\"_blank\">anthony.dimeo@amneal.com<\/a><\/p>\n<p align=\"left\">\n        <strong>Media Contact<\/strong><br \/>\n        <br \/>Brandon Skop<br \/>Sr. Director, Corporate Communications<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=10sAIJHh1KkKmHwHiv8t3sRuWxKlTpqC6hB6tXEElILobdwomt_Mpt2IljbWFgPuIuiOJtL8bwWXE3moe9fScK55lOT7aUKuBxs2ulyu2YgmireARStBxpiI3qw_0Trunm51LEDiw99O1wFGkXjR_luwsp78KHBv1d6Vt2iZt73mYm7lg-vUE8G6_YotQQxBjGDqni4ebhJqbUko_-xKsVuBEXsQU3PZfzF8QqOC5R1-egDCvp2HbatLYtuBHkqWsV-4NgKrjkZGNSC_50O1K1gxaX84uTyT_oh-S61hK6g=\" rel=\"nofollow\" target=\"_blank\">brandon.skop@amneal.com<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTY5MTU3MCM3NTQwMjY2IzIxOTA3Mzc=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/NGFkMTkzNTMtMWJkNi00MTQ1LTljYjAtZDE0NGQ0NWM4NjIzLTEyMDIyOTAtMjAyNi0wNC0yMC1lbg==\/tiny\/Amneal-Pharmaceuticals-LLC.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Phase 4 ELEVATE-PD interim data (n=111) demonstrated clinically meaningful, consistent benefits of CREXONT across all prior treatment groups Demonstrated substantial increases in daily \u201cGood On\u201d time, reductions in \u201cOff\u201d time, and meaningful improvements in motor function after switching to CREXONT\u00ae Patients switching to CREXONT\u00ae from RYTARY\u00ae gained 3.07 hours of additional daily \u201cGood On\u201d time and nearly doubled the duration of continuous \u201cGood On\u201d intervals, enabling longer, uninterrupted periods of effective symptom control BRIDGEWATER, N.J., April 20, 2026 (GLOBE NEWSWIRE) &#8212; Amneal Pharmaceuticals, Inc. (Nasdaq: AMRX) (\u201cAmneal\u201d or the \u201cCompany\u201d), today announced new positive interim results from its ongoing Phase 4 ELEVATE-PD study, presented at the 2026 American Academy of Neurology (AAN). The first 111 patients evaluated after six weeks &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Amneal Announces Additional Positive Interim Phase 4 ELEVATE-PD Results with CREXONT\u00ae for Parkinson\u2019s Disease, Including Over 3 More Hours of Daily \u201cGood On\u201d Time When Switching from RYTARY\u00ae&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-952822","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Amneal Announces Additional Positive Interim Phase 4 ELEVATE-PD Results with CREXONT\u00ae for Parkinson\u2019s Disease, Including Over 3 More Hours of Daily \u201cGood On\u201d Time When Switching from RYTARY\u00ae - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Amneal Announces Additional Positive Interim Phase 4 ELEVATE-PD Results with CREXONT\u00ae for Parkinson\u2019s Disease, Including Over 3 More Hours of Daily \u201cGood On\u201d Time When Switching from RYTARY\u00ae - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Phase 4 ELEVATE-PD interim data (n=111) demonstrated clinically meaningful, consistent benefits of CREXONT across all prior treatment groups Demonstrated substantial increases in daily \u201cGood On\u201d time, reductions in \u201cOff\u201d time, and meaningful improvements in motor function after switching to CREXONT\u00ae Patients switching to CREXONT\u00ae from RYTARY\u00ae gained 3.07 hours of additional daily \u201cGood On\u201d time and nearly doubled the duration of continuous \u201cGood On\u201d intervals, enabling longer, uninterrupted periods of effective symptom control BRIDGEWATER, N.J., April 20, 2026 (GLOBE NEWSWIRE) &#8212; Amneal Pharmaceuticals, Inc. (Nasdaq: AMRX) (\u201cAmneal\u201d or the \u201cCompany\u201d), today announced new positive interim results from its ongoing Phase 4 ELEVATE-PD study, presented at the 2026 American Academy of Neurology (AAN). The first 111 patients evaluated after six weeks &hellip; Continue reading &quot;Amneal Announces Additional Positive Interim Phase 4 ELEVATE-PD Results with CREXONT\u00ae for Parkinson\u2019s Disease, Including Over 3 More Hours of Daily \u201cGood On\u201d Time When Switching from RYTARY\u00ae&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-04-20T12:07:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTY5MTU3MCM3NTQwMjY2IzIxOTA3Mzc=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"9 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Amneal Announces Additional Positive Interim Phase 4 ELEVATE-PD Results with CREXONT\u00ae for Parkinson\u2019s Disease, Including Over 3 More Hours of Daily \u201cGood On\u201d Time When Switching from RYTARY\u00ae\",\"datePublished\":\"2026-04-20T12:07:16+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\\\/\"},\"wordCount\":1780,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTY5MTU3MCM3NTQwMjY2IzIxOTA3Mzc=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/amneal-announces-additional-positive-interim-phase-4-elevate-pd-results-with-crexont-for-parkinsons-disease-including-over-3-more-hours-of-daily-good-on-time-when-swi\\\/\",\"name\":\"Amneal Announces Additional Positive Interim Phase 4 ELEVATE-PD Results with CREXONT\u00ae for Parkinson\u2019s Disease, Including Over 3 More Hours of Daily \u201cGood On\u201d Time When Switching from RYTARY\u00ae - 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