{"id":951713,"date":"2026-04-15T10:12:21","date_gmt":"2026-04-15T14:12:21","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/nexalin-advances-fda-alzheimers-strategy-following-landmark-leadership-meetings-in-the-u-s-and-china\/"},"modified":"2026-04-15T10:12:21","modified_gmt":"2026-04-15T14:12:21","slug":"nexalin-advances-fda-alzheimers-strategy-following-landmark-leadership-meetings-in-the-u-s-and-china","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/nexalin-advances-fda-alzheimers-strategy-following-landmark-leadership-meetings-in-the-u-s-and-china\/","title":{"rendered":"Nexalin Advances FDA Alzheimer\u2019s Strategy Following Landmark Leadership Meetings in the U.S. and China"},"content":{"rendered":"<h2>\nCompany Designing FDA Application Amendments and U.S. Clinical Strategy Leveraging Extensive Real-World Neurostimulation Data Sets Reflecting Broad Clinical Experiences<br \/>\n<\/h2>\n<div class=\"mw_release\">\n<p>HOUSTON, TX, April  15, 2026  (GLOBE NEWSWIRE) &#8212; <b>Nexalin Technology, Inc. (Nasdaq: NXL)<\/b> (the \u201cCompany\u201d or \u201cNexalin\u201d), the leader in non-invasive Deep Intracranial Frequency Stimulation (DIFS\u2122) of the brain, announced the successful completion of a series of high-level meetings in the United States and China focused on advancing the Company\u2019s global clinical strategy for the treatment of Alzheimer\u2019s disease and dementia related cognitive decline. These meetings, including a productive Q-Submission interaction with the U.S. Food and Drug Administration (FDA), represent key milestones in the preparation of Nexalin\u2019s De Novo application with the FDA for the treatment of Alzheimer\u2019s disease. The FDA provided clinical guidance on the proposed Alzheimer\u2019s symptom reduction FDA clinical trial and regulatory pathway. The Nexalin clinical and research teams are currently finalizing the clinical design that will provide primary and secondary endpoints to follow FDA guidance on clinical relevance and treatment response in the Alzheimer\u2019s patient population. The Company plans to submit an amended FDA Q-Submission application based on these strategy meetings in Q2 2026.<\/p>\n<p>The high-level meetings brought together Nexalin leadership, American-based academic research teams and members of the international Alzheimer\u2019s clinical community. Insights gained from these discussions are directly informing Nexalin\u2019s FDA strategy and shaping the final design of its upcoming FDA clinical trial focused on Alzheimer\u2019s disease and age-related cognitive vulnerability.<\/p>\n<p>\u201cThese meetings marked a critical step in aligning our global clinical experience with a disciplined U.S. regulatory and clinical strategy,\u201d said Mark White, President and Chief Executive Officer of Nexalin Technology. \u201cThe meeting insights and observations are directly informing our planned FDA application amendments and design of our FDA Alzheimer\u2019s clinical trial. We believe this regulatory strategy will position Nexalin to become the leader in drug-free, non-invasive treatment focused on the core mechanisms of cognitive decline and the reduction of Alzheimer\u2019s-related symptoms.\u201d<\/p>\n<p>\n        <strong>China Collaboration Highlights Scale of Real-World Clinical Experience<\/strong>\n      <\/p>\n<p>As part of the initiative, Nexalin\u2019s China team continues to meet and collaborate with Professor Yi Tang M.D., PhD, a globally recognized expert in Alzheimer\u2019s disease and geriatric neurology. Professor Tang serves as Vice Chairman of Xuanwu Hospital at Capital Medical University and holds leadership roles at China\u2019s National Neuroscience and Research Center for Geriatric Diseases.<\/p>\n<p>Professor Yi Tang M.D., PhD, brings extensive real-world clinical experience from ongoing studies using Nexalin\u2019s medical device on Alzheimer\u2019s patients in China, representing one of the largest single-center bodies of data involving Nexalin\u2019s non-invasive neurostimulation in aging and dementia-related populations.<\/p>\n<p>\n        <strong>Focus on Core Disease Mechanisms<\/strong>\n      <\/p>\n<p>According to Nexalin leadership, the central theme of Nexalin\u2019s clinical strategy is the importance of addressing disrupted brain networks and thereby reducing the symptoms in Alzheimer\u2019s disease and age-related cognitive decline. Nexalin will continue to focus on resetting and stabilizing disrupted brain networks associated with mental and cognitive impairment. The clinical design and regulatory strategy is built around providing relief to both the Alzheimer\u2019s patient and caretaker. Ultimately, Nexalin intends to provide evidence that Nexalin can slow and possibly delay the need for admission to hospitals and memory care centers for the patient.<\/p>\n<p>Unlike current neurostimulator technologies, Nexalin\u2019s proprietary DIFS technology enables direct stimulation of neurons across the entire brain, delivering targeted intervention for disrupted brain network connectivity. It modulates and encourages the brain\u2019s neural plasticity to restore connectivity and physiological stability. Nexalin\u2019s frequency-based treatment mitigates pathological changes associated with age-related cognitive decline, including Alzheimer\u2019s disease.<\/p>\n<p>\n        <strong>Positioning for Future Clinical and Regulatory Catalysts<\/strong>\n      <\/p>\n<p>Nexalin believes its growing international clinical experience and ongoing research efforts provide a strong foundation for advancing its Alzheimer\u2019s disease strategy in the United States and major global markets. The Company\u2019s approach focuses on restoring disrupted brain networks and improving cognitive stability associated with Alzheimer\u2019s disease using a safe, non-invasive, drug-free neurostimulation medical device.<\/p>\n<p>Nexalin remains committed to advancing brain health in the United States and around the world through rigorous clinical research and education on the Nexalin DIFS non-invasive neurostimulation technology, while adhering to the highest scientific, ethical, and regulatory standards.<\/p>\n<p>\n        <b>About Nexalin Technology, Inc.<\/b>\n      <\/p>\n<p>Nexalin designs and develops innovative neurostimulation products to uniquely help combat the ongoing global mental health epidemic. Nexalin&#8217;s medical devices are non-invasive and undetectable to the human body.\u00a0 Nexalin products are developed to provide relief to those afflicted with mental health issues using bioelectronic medical technology. Nexalin believes its neurostimulation medical devices can penetrate structures deep in the mid-brain that are associated with mental health disorders. Nexalin believes the deeper-penetrating waveform in its next-generation devices will generate enhanced patient response without any adverse side effects. The Nexalin Gen-2 15 milliamp neurostimulation device has been approved in China, Brazil, Oman and Israel. Additional information about the Company is available at: <u><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=ONGRz5pf5QXZfERyqinLk1FA8E7GBktjGeSUS_OWJWUQkJTjAUaIabfas5UFULAdg6thtS_I6QsNLFfHCP5wJBON1uptWgZeMMH1w0qNZUk=\" rel=\"nofollow\" target=\"_blank\">https:\/\/nexalin.com\/<\/a><\/u>.<\/p>\n<p>\n        <b>FORWARD-LOOKING STATEMENTS<\/b>\n      <\/p>\n<p>This press release contains statements that constitute &#8220;forward-looking statements,&#8221; These statements relate to future events or Nexalin\u2019s future financial performance. Any statements that refer to expectations, projections or other characterizations of future events or circumstances or that are not statements of historical fact (including without limitation statements to the effect that Nexalin or its management \u201cbelieves\u201d, \u201cexpects\u201d, \u201canticipates\u201d, \u201cplans\u201d, \u201cintends\u201d and similar expressions) should be considered forward looking statements that involve risks and uncertainties which could cause actual events or Nexalin\u2019s actual results to differ materially from those indicated by the forward-looking statements. Forward-looking statements are subject to numerous conditions, many of which are beyond the control of the Company, including those set forth in the Risk Factors section of the Company&#8217;s Report on Form 10-K for the year ended December 31, 2024 and other filings as filed with the Securities and Exchange Commission. Copies of such filings are available on the SEC&#8217;s website, <u><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=GMQpO5P8N7SDYZyDMg5U4vHsCr3ku-W-5uquFt08aCTt8RLqKbsjabED5AtS4wFAVMNqiEV0RRpEBlvxDR4deQ==\" rel=\"nofollow\" target=\"_blank\">www.sec.gov<\/a><\/u>. Such forward-looking statements are made as of the date hereof and may become outdated over time. The Company undertakes no obligation to update these statements for revisions or changes after the date of this release, except as required by law.<\/p>\n<p>\n        <b>Contact:<\/b>\n      <\/p>\n<p>Crescendo Communications, LLC<br \/>Tel: (212) 671-1020<br \/>Email: NXL@crescendo-ir.com<\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTY5MDQwNiM3NTM3MjI0IzUwMDEwOTExMw==\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/ZDI1NjkxYWItZTA1OC00ZmIyLWFhOWEtN2M3MTE5OTc1ZGVkLTUwMDEwOTExMy0yMDI2LTA0LTE1LWVu\/tiny\/Nexalin-Technology-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Company Designing FDA Application Amendments and U.S. Clinical Strategy Leveraging Extensive Real-World Neurostimulation Data Sets Reflecting Broad Clinical Experiences HOUSTON, TX, April 15, 2026 (GLOBE NEWSWIRE) &#8212; Nexalin Technology, Inc. (Nasdaq: NXL) (the \u201cCompany\u201d or \u201cNexalin\u201d), the leader in non-invasive Deep Intracranial Frequency Stimulation (DIFS\u2122) of the brain, announced the successful completion of a series of high-level meetings in the United States and China focused on advancing the Company\u2019s global clinical strategy for the treatment of Alzheimer\u2019s disease and dementia related cognitive decline. These meetings, including a productive Q-Submission interaction with the U.S. Food and Drug Administration (FDA), represent key milestones in the preparation of Nexalin\u2019s De Novo application with the FDA for the treatment of Alzheimer\u2019s disease. The FDA &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/nexalin-advances-fda-alzheimers-strategy-following-landmark-leadership-meetings-in-the-u-s-and-china\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Nexalin Advances FDA Alzheimer\u2019s Strategy Following Landmark Leadership Meetings in the U.S. and China&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-951713","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nexalin Advances FDA Alzheimer\u2019s Strategy Following Landmark Leadership Meetings in the U.S. and China - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/nexalin-advances-fda-alzheimers-strategy-following-landmark-leadership-meetings-in-the-u-s-and-china\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nexalin Advances FDA Alzheimer\u2019s Strategy Following Landmark Leadership Meetings in the U.S. and China - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Company Designing FDA Application Amendments and U.S. Clinical Strategy Leveraging Extensive Real-World Neurostimulation Data Sets Reflecting Broad Clinical Experiences HOUSTON, TX, April 15, 2026 (GLOBE NEWSWIRE) &#8212; Nexalin Technology, Inc. (Nasdaq: NXL) (the \u201cCompany\u201d or \u201cNexalin\u201d), the leader in non-invasive Deep Intracranial Frequency Stimulation (DIFS\u2122) of the brain, announced the successful completion of a series of high-level meetings in the United States and China focused on advancing the Company\u2019s global clinical strategy for the treatment of Alzheimer\u2019s disease and dementia related cognitive decline. These meetings, including a productive Q-Submission interaction with the U.S. Food and Drug Administration (FDA), represent key milestones in the preparation of Nexalin\u2019s De Novo application with the FDA for the treatment of Alzheimer\u2019s disease. 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(Nasdaq: NXL) (the \u201cCompany\u201d or \u201cNexalin\u201d), the leader in non-invasive Deep Intracranial Frequency Stimulation (DIFS\u2122) of the brain, announced the successful completion of a series of high-level meetings in the United States and China focused on advancing the Company\u2019s global clinical strategy for the treatment of Alzheimer\u2019s disease and dementia related cognitive decline. These meetings, including a productive Q-Submission interaction with the U.S. Food and Drug Administration (FDA), represent key milestones in the preparation of Nexalin\u2019s De Novo application with the FDA for the treatment of Alzheimer\u2019s disease. 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