{"id":929169,"date":"2026-01-21T08:06:30","date_gmt":"2026-01-21T13:06:30","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/acacia-clinics-and-vagus-nerve-society-conduct-study-using-electrocores-gammacore-sapphire-for-adjunctive-treatment-of-symptoms-associated-with-post-traumatic-stress-disorder-ptsd\/"},"modified":"2026-01-21T08:06:30","modified_gmt":"2026-01-21T13:06:30","slug":"acacia-clinics-and-vagus-nerve-society-conduct-study-using-electrocores-gammacore-sapphire-for-adjunctive-treatment-of-symptoms-associated-with-post-traumatic-stress-disorder-ptsd","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/acacia-clinics-and-vagus-nerve-society-conduct-study-using-electrocores-gammacore-sapphire-for-adjunctive-treatment-of-symptoms-associated-with-post-traumatic-stress-disorder-ptsd\/","title":{"rendered":"Acacia Clinics and Vagus Nerve Society Conduct Study Using electroCore\u2019s gammaCore Sapphire for Adjunctive Treatment of Symptoms Associated with Post-Traumatic Stress Disorder (\u201cPTSD\u201d)"},"content":{"rendered":"
\n

ROCKAWAY, N.J., Jan. 21, 2026 (GLOBE NEWSWIRE) — electroCore, Inc. (Nasdaq: ECOR) (\u201celectroCore\u201d or the \u201cCompany\u201d), a bioelectronic technology company, today announced that Acacia Clinics and the Vagus Nerve Society have launched a new research initiative to explore the extent to which gammaCore\u2122 Sapphire, electroCore\u2019s non-invasive vagus nerve stimulator (nVNS), can be used as an adjunctive treatment of symptoms associated with PTSD.<\/p>\n

The study entitled \u201cNon-Invasive Vagus Nerve Stimulation (nVNS) for Adjunctive Treatment of Symptoms Associated with Post-Traumatic Stress Disorder,<\/em>\u201d will be led by Danielle DeSouza MSc, PhD, VP of Research at Acacia Clinics (\u201cthe Investigator\u201d). The study will collect data on the safety and effectiveness of gammaCore Sapphire as an adjunctive treatment for the symptoms of PTSD. The primary safety measure for this study is the incidence and occurrence of significant adverse events (SAEs) related to nVNS treatment, while the primary efficacy outcome is the difference from baseline in the Clinician-Administered PTSD Scale (CAPS-5) total score at the 12-week treatment period (versus baseline\/4-week run-in period). The CAPS-5 is a semi-structured clinical interview administered by the Investigator and is used to assess index history of DSM-5 defined traumatic event exposure, including the most distressing event, time since exposure, and total number of exposures, as well as frequency and severity of post-traumatic stress symptoms, as evidenced by CAPS-5 total score. The CAPS-5 provides diagnostic status (presence versus absence) of PTSD as well as PTSD symptom severity. A secondary efficacy outcome will include the difference in the PTSD Checklist (PCL-5) score, a 20-item self-report questionnaire in which respondents indicate the presence and severity of PTSD symptoms derived from the DSM-5 symptoms of PTSD, and clinical improvement with the Clinical Global Index (CGI) at the 12-week treatment period (versus baseline).<\/p>\n

\u201cPost-traumatic stress disorder affects 6% of the population at some time in their lives, with only one third of those suffering from PTSD able to achieve full remission with current standard of care,\u201d commented Danielle DeSouza MSc, PhD. \u201cThe vagus nerve represents a unique window between central functions of the brain and peripheral organ function that may be a promising target for treatment interventions for PTSD, and we are excited to collaborate with the Vagus Nerve Society and electroCore in understanding how nVNS may be used to treat symptoms of PTSD.\u201d<\/p>\n

The study will enroll up to 40 subjects aged between 18 \u2013 70 diagnosed with PTSD and is anticipated to run over 10 months. The study is sponsored by the Vagus Nerve Society and electroCore will be providing an educational grant and gammaCore Sapphire devices.\u00a0\u00a0<\/p>\n

\n About Acacia Clinics<\/strong>\n <\/p>\n

Acacia Clinics is a recognized leader in precision neuromodulation and advanced mental health services, drawing on nearly a decade of experience in fMRI-guided TMS. Founded in 2018 by Dr. David Carreon and Dr. Nathan Meng, Acacia is led by an experienced executive team that also includes David Ling, Dr. Noah DeGaetano, and Dr. Danielle DeSouza. Acacia integrates patient-focused care, rigorous clinical research, and industry-leading partnerships to deliver exceptional, evidence-based treatment.<\/p>\n

\n About electroCore, Inc.<\/strong>\n <\/p>\n

electroCore, Inc. is a bioelectronic technology company whose mission is to improve health and quality of life through innovative non-invasive bioelectronic technologies. The Company\u2019s two leading prescription products, gammaCore\u00ae non-invasive vagus nerve stimulation (nVNS) and Quell\u00ae neurostimulator, treat chronic pain syndromes through non-invasive neuromodulation technology. Additionally, the company commercializes its handheld, and personal use Truvaga\u2122 and TAC-STIM\u2122 nVNS products utilizing bioelectronic technologies to promote general wellness and human performance.<\/p>\n

For more information, visit www.electrocore.com.<\/p>\n

\n Forward-Looking Statements<\/strong>\n <\/p>\n

This press release and other written and oral statements made by representatives of electroCore may contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include, but are not limited to, statements about the anticipated results from the study using gammaCore-Sapphire for adjunctive treatment of symptoms associated with PTSD, the Company\u2019s relationship with the Vagus Nerve Society and Acacia Clinics, the Company\u2019s future business strategies, growth opportunities, prospects, product development, and market expansion, and other statements that are not historical in nature, particularly those that utilize terminology such as \u201canticipates,\u201d \u201cwill,\u201d \u201cexpects,\u201d \u201cbelieves,\u201d \u201cintends,\u201d and other words of similar meaning, derivations of such words and the use of future dates. Actual results could differ from those projected in any forward-looking statements due to numerous factors. Such factors include, among others, the ability to use strategic partnerships to provide more accessibility to those looking to purchase our consumer devices, the inherent uncertainties associated with developing new products or technologies, the ability to commercialize its products, electroCore\u2019s results of operations and financial performance, inflation and currency fluctuations, and any expectations electroCore may have with respect thereto, competition in the industry in which electroCore operates and overall economic and market conditions. Any forward-looking statements are made as of the date of this press release, and electroCore assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in the forward-looking statements, except as required by law. Investors should consult all of the information set forth herein and should also refer to the risk factor disclosure set forth in the reports and other documents electroCore files with the SEC available at www.sec.gov<\/a>.<\/p>\n

\n Contact:<\/strong>\n <\/p>\n

ECOR Investor Relations
(973) 302-9253
investors@electrocore.com<\/p>\n

\"\"
\n
\n \"\"\n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

ROCKAWAY, N.J., Jan. 21, 2026 (GLOBE NEWSWIRE) — electroCore, Inc. (Nasdaq: ECOR) (\u201celectroCore\u201d or the \u201cCompany\u201d), a bioelectronic technology company, today announced that Acacia Clinics and the Vagus Nerve Society have launched a new research initiative to explore the extent to which gammaCore\u2122 Sapphire, electroCore\u2019s non-invasive vagus nerve stimulator (nVNS), can be used as an adjunctive treatment of symptoms associated with PTSD. The study entitled \u201cNon-Invasive Vagus Nerve Stimulation (nVNS) for Adjunctive Treatment of Symptoms Associated with Post-Traumatic Stress Disorder,\u201d will be led by Danielle DeSouza MSc, PhD, VP of Research at Acacia Clinics (\u201cthe Investigator\u201d). The study will collect data on the safety and effectiveness of gammaCore Sapphire as an adjunctive treatment for the symptoms of PTSD. The primary … <\/p>\n

Continue reading “Acacia Clinics and Vagus Nerve Society Conduct Study Using electroCore\u2019s gammaCore Sapphire for Adjunctive Treatment of Symptoms Associated with Post-Traumatic Stress Disorder (\u201cPTSD\u201d)”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-929169","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nAcacia Clinics and Vagus Nerve Society Conduct Study Using electroCore\u2019s gammaCore Sapphire for Adjunctive Treatment of Symptoms Associated with Post-Traumatic Stress Disorder (\u201cPTSD\u201d) - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/acacia-clinics-and-vagus-nerve-society-conduct-study-using-electrocores-gammacore-sapphire-for-adjunctive-treatment-of-symptoms-associated-with-post-traumatic-stress-disorder-ptsd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Acacia Clinics and Vagus Nerve Society Conduct Study Using electroCore\u2019s gammaCore Sapphire for Adjunctive Treatment of Symptoms Associated with Post-Traumatic Stress Disorder (\u201cPTSD\u201d) - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"ROCKAWAY, N.J., Jan. 21, 2026 (GLOBE NEWSWIRE) — electroCore, Inc. (Nasdaq: ECOR) (\u201celectroCore\u201d or the \u201cCompany\u201d), a bioelectronic technology company, today announced that Acacia Clinics and the Vagus Nerve Society have launched a new research initiative to explore the extent to which gammaCore\u2122 Sapphire, electroCore\u2019s non-invasive vagus nerve stimulator (nVNS), can be used as an adjunctive treatment of symptoms associated with PTSD. The study entitled \u201cNon-Invasive Vagus Nerve Stimulation (nVNS) for Adjunctive Treatment of Symptoms Associated with Post-Traumatic Stress Disorder,\u201d will be led by Danielle DeSouza MSc, PhD, VP of Research at Acacia Clinics (\u201cthe Investigator\u201d). The study will collect data on the safety and effectiveness of gammaCore Sapphire as an adjunctive treatment for the symptoms of PTSD. 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(Nasdaq: ECOR) (\u201celectroCore\u201d or the \u201cCompany\u201d), a bioelectronic technology company, today announced that Acacia Clinics and the Vagus Nerve Society have launched a new research initiative to explore the extent to which gammaCore\u2122 Sapphire, electroCore\u2019s non-invasive vagus nerve stimulator (nVNS), can be used as an adjunctive treatment of symptoms associated with PTSD. The study entitled \u201cNon-Invasive Vagus Nerve Stimulation (nVNS) for Adjunctive Treatment of Symptoms Associated with Post-Traumatic Stress Disorder,\u201d will be led by Danielle DeSouza MSc, PhD, VP of Research at Acacia Clinics (\u201cthe Investigator\u201d). The study will collect data on the safety and effectiveness of gammaCore Sapphire as an adjunctive treatment for the symptoms of PTSD. 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