{"id":921548,"date":"2025-12-19T11:07:41","date_gmt":"2025-12-19T16:07:41","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/"},"modified":"2025-12-19T11:07:41","modified_gmt":"2025-12-19T16:07:41","slug":"tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/","title":{"rendered":"Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"left\">BOSTON, Dec.  19, 2025  (GLOBE NEWSWIRE) &#8212; Tiziana Life Sciences, Ltd. (Nasdaq:\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=xMRvvfCW38_-eP_gUv06S8hlczyrGJTRgdi0T8dYwzQIrVcRDq9LL0WsQJKUchG-k929taxRd2CYnBdy7msSPF8c_ZAyjbfokyaOg47B1R6DwejsNmYJzWlirlugcZLH\" rel=\"nofollow\" target=\"_blank\">TLSA<\/a>) (\u201cTiziana\u201d or the \u201cCompany\u201d), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announces that its Executive Chairman and Founder, Mr. Gabriele Cerrone, has purchased 97,687 common shares, bringing his total holding to 43,374,830 common shares, which is 36.08% of issued share capital.<\/p>\n<p align=\"left\">\n        <strong>About Foralumab<\/strong>\n      <\/p>\n<p align=\"left\">Foralumab, a fully human anti-CD3 monoclonal antibody, is a biological drug candidate that has been shown to stimulate T regulatory cells when dosed intranasally. At present, 14 patients with Non-Active Secondary Progressive Multiple Sclerosis (na-SPMS) have been dosed in an open-label intermediate sized Expanded Access (EA) Program (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=RXlO8fGdlX08qSxjee6wcVhWCbkaI2EBXL4Hua_FDNCp-Wc3zpQ_9qaLLxBNq38biLDLGFNIt6DlYg93y8NiIs8HUvcoA8kHXupq-toqvjrpgCgwEK9ZJ7bn-5nnr4q6\" rel=\"nofollow\" target=\"_blank\">NCT06802328<\/a>) with either an improvement or stability of disease seen within 6 months in all patients. In addition, intranasal foralumab is currently being studied in a Phase 2a, randomized, double-blind, placebo-controlled, multicenter, dose-ranging trial in patients with non-active secondary progressive multiple sclerosis (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=RXlO8fGdlX08qSxjee6wcSUIkpVEPYVVASUx_4uvb8k29W8wJAHl76CYVSnOUQB7SaBs5UL_qhW8dWeFsxST5qZprq8JflBiIO1ybTAz5B0z5B6zXCw8A1PR6IZ3RPD-\" rel=\"nofollow\" target=\"_blank\">NCT06292923<\/a>).<\/p>\n<p align=\"left\">Foralumab is the only fully human anti-CD3 monoclonal antibody (mAb) currently in clinical development. Immunomodulation by intranasal foralumab represents a novel avenue for the treatment of neuroinflammatory and neurodegenerative human diseases.<sup>[1],[2]<\/sup><\/p>\n<p align=\"left\">\n        <strong>About Tiziana Life Sciences<\/strong>\n      <\/p>\n<p align=\"left\">Tiziana Life Sciences is a clinical-stage biopharmaceutical company developing breakthrough therapies using transformational drug delivery technologies to enable alternative routes of immunotherapy. Tiziana\u2019s innovative intranasal approach has the potential to provide an improvement in efficacy as well as safety and tolerability compared to intravenous (IV) delivery. Tiziana\u2019s lead candidate, intranasal foralumab, which is the only fully human anti-CD3 mAb currently in clinical development, has demonstrated a favorable safety profile and clinical response in patients in studies to date. Tiziana\u2019s technology for alternative routes of immunotherapy has been patented with several applications pending and is expected to allow for broad pipeline applications.<\/p>\n<p align=\"left\">For more information about Tiziana Life Sciences and its innovative pipeline of therapies, please visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=9xXFs1AXW2kEIR_uX6k0zkiO7ilpVTyhyitmh-FURBVrww8ZFLnwCUmByX6wqCLnqDik_oAEeiABHuLhJvPSazFAPgZoaPgF160P825zMxyoA57Et2IvgDin6TfYrmcW\" rel=\"nofollow\" target=\"_blank\">www.tizianalifesciences.com<\/a>.<\/p>\n<p align=\"left\">\n        <strong>For further inquiries:<\/strong>\n      <\/p>\n<p align=\"left\">\n        <strong>Tiziana Life Sciences Ltd<\/strong><br \/>\n        <br \/>Paul Spencer, Business Development, and Investor Relations<br \/>+44 (0) 207 495 2379<br \/>email:\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=QuRpryj1omjNrwj3gNNBT51xI7IFvkkFVHDnoIaKwinR5Pfaz0tr0V1M7D8vbzXTpINSkxsbXEVRk19eN274-Nhra-jgeLrCNp_0tkrO_pTgAYyfDZ_rXeaba4tglfO8\" rel=\"nofollow\" target=\"_blank\">info@tizianalifesciences.com<\/a><\/p>\n<p align=\"left\">___________________<br \/>[1] <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=yYQsuMKejI2iAJuowAunAVOn8u9PoeGl7M5KDGTuByQmoc-DqFeq1vYWnuYBe1Bao_XS0xqnKWKKfZ4gquT_7Z8Pg8ZmJbEwTlUNI2T3SZlzln5Ep3SuBh5iA5LwNJ81nWFtDWDS4-AaUCvn3Bo7KghDuUrwnn_do9Qm3ZqJcvg=\" rel=\"nofollow\" target=\"_blank\">https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2220272120<\/a><br \/>[2]\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=yYQsuMKejI2iAJuowAunAVOn8u9PoeGl7M5KDGTuByQmoc-DqFeq1vYWnuYBe1BaWCFiOgEqWrcYS43Tc3svzBQztPS6XYaG7cCJOv8QNK_8Uz42cHT1lFGBNpP9fY6IlCRXE0eCvJ-V6bSGsRMClPT4n3DfrugTwMQ_E-uk6IE=\" rel=\"nofollow\" target=\"_blank\">https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2309221120<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTYwNTIxMSM3MzMwODUzIzIxMjM4ODU=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/YzBkNmIwYjctMDFlOC00ZTM4LTlkMTQtOTRiMDg2MzQ3ODg4LTExMzU0NTYtMjAyNS0xMi0xOS1lbg==\/tiny\/Tiziana-Life-Sciences-Plc.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>BOSTON, Dec. 19, 2025 (GLOBE NEWSWIRE) &#8212; Tiziana Life Sciences, Ltd. (Nasdaq:\u00a0TLSA) (\u201cTiziana\u201d or the \u201cCompany\u201d), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announces that its Executive Chairman and Founder, Mr. Gabriele Cerrone, has purchased 97,687 common shares, bringing his total holding to 43,374,830 common shares, which is 36.08% of issued share capital. About Foralumab Foralumab, a fully human anti-CD3 monoclonal antibody, is a biological drug candidate that has been shown to stimulate T regulatory cells when dosed intranasally. At present, 14 patients with Non-Active Secondary Progressive Multiple Sclerosis (na-SPMS) have been dosed in an open-label intermediate sized Expanded Access (EA) Program (NCT06802328) with either an &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-921548","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"BOSTON, Dec. 19, 2025 (GLOBE NEWSWIRE) &#8212; Tiziana Life Sciences, Ltd. (Nasdaq:\u00a0TLSA) (\u201cTiziana\u201d or the \u201cCompany\u201d), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announces that its Executive Chairman and Founder, Mr. Gabriele Cerrone, has purchased 97,687 common shares, bringing his total holding to 43,374,830 common shares, which is 36.08% of issued share capital. About Foralumab Foralumab, a fully human anti-CD3 monoclonal antibody, is a biological drug candidate that has been shown to stimulate T regulatory cells when dosed intranasally. At present, 14 patients with Non-Active Secondary Progressive Multiple Sclerosis (na-SPMS) have been dosed in an open-label intermediate sized Expanded Access (EA) Program (NCT06802328) with either an &hellip; Continue reading &quot;Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-12-19T16:07:41+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTYwNTIxMSM3MzMwODUzIzIxMjM4ODU=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman\",\"datePublished\":\"2025-12-19T16:07:41+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\\\/\"},\"wordCount\":350,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTYwNTIxMSM3MzMwODUzIzIxMjM4ODU=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\\\/\",\"name\":\"Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman - 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(Nasdaq:\u00a0TLSA) (\u201cTiziana\u201d or the \u201cCompany\u201d), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announces that its Executive Chairman and Founder, Mr. Gabriele Cerrone, has purchased 97,687 common shares, bringing his total holding to 43,374,830 common shares, which is 36.08% of issued share capital. About Foralumab Foralumab, a fully human anti-CD3 monoclonal antibody, is a biological drug candidate that has been shown to stimulate T regulatory cells when dosed intranasally. At present, 14 patients with Non-Active Secondary Progressive Multiple Sclerosis (na-SPMS) have been dosed in an open-label intermediate sized Expanded Access (EA) Program (NCT06802328) with either an &hellip; Continue reading \"Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/","og_site_name":"Market Newsdesk","article_published_time":"2025-12-19T16:07:41+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTYwNTIxMSM3MzMwODUzIzIxMjM4ODU=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman","datePublished":"2025-12-19T16:07:41+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/"},"wordCount":350,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTYwNTIxMSM3MzMwODUzIzIxMjM4ODU=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-acquisition-of-shares-by-executive-chairman\/","name":"Tiziana Life Sciences Announces Acquisition of Shares by Executive Chairman - 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