{"id":913369,"date":"2025-11-24T18:42:54","date_gmt":"2025-11-24T23:42:54","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/"},"modified":"2025-11-24T18:42:54","modified_gmt":"2025-11-24T23:42:54","slug":"mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/","title":{"rendered":"Mesoblast Trading Update at Annual General Meeting Highlights Continued Strong Growth in Ryoncil\u00ae Revenue"},"content":{"rendered":"
\n

NEW YORK, Nov. 24, 2025 (GLOBE NEWSWIRE) — Mesoblast Limited (Nasdaq:MESO; ASX:MSB), global leader in allogeneic cellular medicines for inflammatory diseases, today provided a trading update, together with a comprehensive operational overview, as part of the Chief Executive\u2019s Annual General Meeting (AGM) address.<\/p>\n

For the quarter ending December 31, 2025, management expects gross revenue of more than US$30.0 million from sales of Ryoncil\u00ae<\/sup> (remestemcel-L-rknd). This represents more than 37% increase on the US$21.9 million in gross revenue from Ryoncil\u00ae<\/sup> in the prior quarter ended September 30, 2025.<\/p>\n

\n About Mesoblast <\/strong>
\n
Mesoblast (the Company) is a world leader in developing allogeneic (off-the-shelf) cellular medicines for the treatment of severe and life-threatening inflammatory conditions. The therapies from the Company\u2019s proprietary mesenchymal lineage cell therapy technology platform respond to severe inflammation by releasing anti-inflammatory factors that counter and modulate multiple effector arms of the immune system, resulting in significant reduction of the damaging inflammatory process.<\/p>\n

Mesoblast\u2019s Ryoncil\u00ae<\/sup> (remestemcel-L-rknd) for the treatment of steroid-refractory acute graft versus host disease (SR-aGvHD) in pediatric patients 2 months and older is the first FDA-approved mesenchymal stromal cell (MSC) therapy. Please see the full Prescribing Information at www.ryoncil.com<\/a>.<\/p>\n

Mesoblast is committed to developing additional cell therapies for distinct indications based on its remestemcel-L and rexlemestrocel-L allogeneic stromal cell technology platforms. Ryoncil\u00ae<\/sup> is being developed for additional inflammatory diseases including SR-aGvHD in adults and biologic-resistant inflammatory bowel disease. Rexlemestrocel-L is being developed for heart failure and chronic low back pain. The Company has established commercial partnerships in Japan, Europe and China.<\/p>\n

\n About Mesoblast intellectual property: <\/strong>Mesoblast has a strong and extensive global intellectual property portfolio, with over 1,000 granted patents or patent applications covering mesenchymal stromal cell compositions of matter, methods of manufacturing and indications. These granted patents and patent applications provide commercial protection extending through to at least 2044 in all major markets.<\/p>\n

\n About Mesoblast manufacturing: <\/strong>The Company\u2019s proprietary manufacturing processes yield industrial-scale, cryopreserved, off-the-shelf, cellular medicines. These cell therapies, with defined pharmaceutical release criteria, are planned to be readily available to patients worldwide.<\/p>\n

Mesoblast has locations in Australia, the United States and Singapore and is listed on the Australian Securities Exchange (MSB) and on the Nasdaq (MESO). For more information, please see www.mesoblast.com<\/a>, LinkedIn: Mesoblast Limited and X: @Mesoblast<\/p>\n

\n Forward-Looking Statements<\/strong>
\n
This press release includes forward-looking statements and forecasts that relate to future events or our future financial performance and involve known and unknown risks, uncertainties and other factors that may cause our actual results, levels of activity, performance or achievements to differ materially from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. We make such forward-looking statements pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and other federal securities laws. Forward-looking statements should not be read as a guarantee of future performance or results, and actual results may differ from the results anticipated in these forward-looking statements, and the differences may be material and adverse. Forward-looking statements include, but are not limited to, statements about: the initiation, timing, progress and results of Mesoblast\u2019s preclinical and clinical studies, and Mesoblast\u2019s research and development programs; Mesoblast\u2019s ability to advance product candidates into, enroll and successfully complete, clinical studies, including multi-national clinical trials; Mesoblast\u2019s ability to advance its manufacturing capabilities; the timing or likelihood of regulatory filings and approvals, manufacturing activities and product marketing activities, if any; the commercialization of Mesoblast\u2019s RYONCIL for pediatric SR-aGVHD and any other product candidates, if approved; regulatory or public perceptions and market acceptance surrounding the use of stem-cell based therapies; the potential for Mesoblast\u2019s product candidates, if any are approved, to be withdrawn from the market due to patient adverse events or deaths; the potential benefits of strategic collaboration agreements and Mesoblast\u2019s ability to enter into and maintain established strategic collaborations; Mesoblast\u2019s ability to establish and maintain intellectual property on its product candidates and Mesoblast\u2019s ability to successfully defend these in cases of alleged infringement; the scope of protection Mesoblast is able to establish and maintain for intellectual property rights covering its product candidates and technology; estimates of Mesoblast\u2019s expenses, future revenues, capital requirements and its needs for additional financing; Mesoblast\u2019s financial performance; developments relating to Mesoblast\u2019s competitors and industry; and the pricing and reimbursement of Mesoblast\u2019s product candidates, if approved. You should read this press release together with our risk factors, in our most recently filed reports with the SEC or on our website. Uncertainties and risks that may cause Mesoblast\u2019s actual results, performance or achievements to be materially different from those which may be expressed or implied by such statements, and accordingly, you should not place undue reliance on these forward-looking statements. We do not undertake any obligations to publicly update or revise any forward-looking statements, whether as a result of new information, future developments or otherwise, except where required by law or the ASX Listing Rules. Past performance given in this announcement is given for illustrative purposes only and should not be relied on as (and is not) an indication of future performance.<\/p>\n

\n Not financial product advice<\/strong>\n <\/p>\n

This announcement does not constitute financial product advice or investment advice (nor tax, accounting or legal advice) and has been prepared without taking into account the objectives, financial situation or needs of individuals. Before making an investment decision, prospective investors should consider the appropriateness of the information having regard to their own objectives, financial situation and needs and seek appropriate professional advice.<\/p>\n

\n Disclaimer<\/strong>\n <\/p>\n

To the maximum extent permitted by law, Mesoblast and its directors, officers, employees, advisers and agents disclaim any obligation or undertaking to release any updates or revisions to the information to reflect any change in expectations or assumptions, and disclaim all responsibility and liability for these forward-looking statements (including, without limitation, any liability for negligence).<\/p>\n

Release authorizedby the Chief Executive.<\/p>\n

\n For more information, please contact:<\/em>\n <\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n
\n Corporate Communications \/ Investors<\/em>
\n <\/strong>\n <\/td>\n		\u00a0<\/td>\n<\/tr>\n
Paul Hughes<\/td>\n\u00a0<\/td>\n<\/tr>\n
T: +61 3 9639 6036<\/td>\n\u00a0<\/td>\n<\/tr>\n
\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n
\n
\n Media \u2013 Global <\/em>
\n <\/strong>\n <\/td>\n		\u00a0<\/td>\n<\/tr>\n
Allison Worldwide<\/td>\n\u00a0<\/td>\n<\/tr>\n
Emma Neal<\/td>\n\u00a0<\/td>\n<\/tr>\n
T: +1 603 545 4843<\/td>\n\u00a0<\/td>\n<\/tr>\n
E: emma.neal@allisonworldwide.com<\/a><\/td>\n\u00a0<\/td>\n<\/tr>\n
\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n
\n
\n Media \u2013 Australia<\/em>
\n <\/strong>\n <\/td>\n		\u00a0<\/td>\n<\/tr>\n
BlueDot Media<\/td>\n\u00a0<\/td>\n<\/tr>\n
Steve Dabkowski<\/td>\n\u00a0<\/td>\n<\/tr>\n
T: +61 419 880 486<\/td>\n\u00a0<\/td>\n<\/tr>\n
E: steve@bluedot.net.au<\/a><\/td>\n\u00a0<\/td>\n<\/tr>\n<\/table>\n

\n \n <\/p>\n

\"\"
\n
\n \"\"\n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

NEW YORK, Nov. 24, 2025 (GLOBE NEWSWIRE) — Mesoblast Limited (Nasdaq:MESO; ASX:MSB), global leader in allogeneic cellular medicines for inflammatory diseases, today provided a trading update, together with a comprehensive operational overview, as part of the Chief Executive\u2019s Annual General Meeting (AGM) address. For the quarter ending December 31, 2025, management expects gross revenue of more than US$30.0 million from sales of Ryoncil\u00ae (remestemcel-L-rknd). This represents more than 37% increase on the US$21.9 million in gross revenue from Ryoncil\u00ae in the prior quarter ended September 30, 2025. About Mesoblast Mesoblast (the Company) is a world leader in developing allogeneic (off-the-shelf) cellular medicines for the treatment of severe and life-threatening inflammatory conditions. The therapies from the Company\u2019s proprietary mesenchymal lineage cell … <\/p>\n

Continue reading “Mesoblast Trading Update at Annual General Meeting Highlights Continued Strong Growth in Ryoncil\u00ae Revenue”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-913369","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nMesoblast Trading Update at Annual General Meeting Highlights Continued Strong Growth in Ryoncil\u00ae Revenue - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mesoblast Trading Update at Annual General Meeting Highlights Continued Strong Growth in Ryoncil\u00ae Revenue - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"NEW YORK, Nov. 24, 2025 (GLOBE NEWSWIRE) — Mesoblast Limited (Nasdaq:MESO; ASX:MSB), global leader in allogeneic cellular medicines for inflammatory diseases, today provided a trading update, together with a comprehensive operational overview, as part of the Chief Executive\u2019s Annual General Meeting (AGM) address. For the quarter ending December 31, 2025, management expects gross revenue of more than US$30.0 million from sales of Ryoncil\u00ae (remestemcel-L-rknd). This represents more than 37% increase on the US$21.9 million in gross revenue from Ryoncil\u00ae in the prior quarter ended September 30, 2025. About Mesoblast Mesoblast (the Company) is a world leader in developing allogeneic (off-the-shelf) cellular medicines for the treatment of severe and life-threatening inflammatory conditions. 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For the quarter ending December 31, 2025, management expects gross revenue of more than US$30.0 million from sales of Ryoncil\u00ae (remestemcel-L-rknd). This represents more than 37% increase on the US$21.9 million in gross revenue from Ryoncil\u00ae in the prior quarter ended September 30, 2025. About Mesoblast Mesoblast (the Company) is a world leader in developing allogeneic (off-the-shelf) cellular medicines for the treatment of severe and life-threatening inflammatory conditions. The therapies from the Company\u2019s proprietary mesenchymal lineage cell … Continue reading \"Mesoblast Trading Update at Annual General Meeting Highlights Continued Strong Growth in Ryoncil\u00ae Revenue\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/","og_site_name":"Market Newsdesk","article_published_time":"2025-11-24T23:42:54+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTU5MTczNCM3MjkxMjA2IzIwMTc0MzI=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Mesoblast Trading Update at Annual General Meeting Highlights Continued Strong Growth in Ryoncil\u00ae Revenue","datePublished":"2025-11-24T23:42:54+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/"},"wordCount":1026,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTU5MTczNCM3MjkxMjA2IzIwMTc0MzI=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/mesoblast-trading-update-at-annual-general-meeting-highlights-continued-strong-growth-in-ryoncil-revenue\/","name":"Mesoblast Trading Update at Annual General Meeting Highlights Continued Strong Growth in Ryoncil\u00ae Revenue - 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