{"id":906091,"date":"2025-11-05T15:55:11","date_gmt":"2025-11-05T20:55:11","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\/"},"modified":"2025-11-05T15:55:11","modified_gmt":"2025-11-05T20:55:11","slug":"tempest-reports-third-quarter-2025-financial-results-and-provides-business-update","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\/","title":{"rendered":"Tempest Reports Third Quarter 2025 Financial Results and Provides Business Update"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"justify\">BRISBANE, Calif., Nov.  05, 2025  (GLOBE NEWSWIRE) &#8212; Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company with a pipeline of first-in-class<sup>1<\/sup> targeted and immune-mediated therapeutics to fight cancer, today reported financial results for the quarter ended September 30, 2025 and provided a corporate update.<\/p>\n<p align=\"justify\">\u201cWe are continuing our strategic alternatives process with the goal of maximizing value for stockholders,\u201d said Stephen Brady, president and chief executive officer of Tempest. \u201cIn addition, we look forward to the start of the TPST-1495 Phase 2 in collaboration with the NCI and the Cancer Prevention Clinical Trials Network and remain confident in the potential of amezalpat to transform the treatment of first-line HCC and bring meaningful benefit to patients and their families.\u201d<\/p>\n<p align=\"justify\">\u2014\u2014\u2014\u2014\u2014\u2014\u00a0 <br \/><sup>1<\/sup> If approved by the U.S. Food and Drug Administration (FDA).<\/p>\n<p>\n        <strong>Financial Results<\/strong>\n      <\/p>\n<p align=\"justify\">\n        <em>Third Quarter 2025<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-bottom:6pt;text-align:justify\">Tempest ended the quarter with $7.5 million in cash and cash equivalents, compared to $30.3 million on December 31, 2024. The decrease was primarily due to cash used in operating activities, offset by $4.1 million in net proceeds from the June 2025 registered direct offering, as well as $2.8 million in net proceeds from the company\u2019s at-the-market offering program.<\/li>\n<li style=\"margin-bottom:6pt;text-align:justify\">Net loss and net loss per share for the quarter were $3.5 million and $0.79, respectively, compared to $10.6 million and $5.32, respectively, for the same period in 2024.<\/li>\n<li style=\"margin-bottom:6pt;text-align:justify\">Research and development expenses for the quarter were $0.6 million, compared to $7.6 million for the same period in 2024. The $7.0 million decrease was primarily due to a decrease in costs incurred as a result of re-prioritizing efforts towards exploring strategic alternatives.<\/li>\n<li style=\"margin-bottom:6pt;text-align:justify\">General and administrative expenses for the quarter were $3.0 million, compared to $3.0 million for the same period in 2024, and were primarily related to consulting and professional services.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <em>Year-to-Date<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-bottom:6pt;text-align:justify\">Cash used in operating activities for the nine months ended September 30, 2025 was $23.2 million.<\/li>\n<li style=\"margin-bottom:6pt;text-align:justify\">Net loss and net loss per share for the nine months ended September 30, 2025 were $22.2 million and $5.71, respectively, compared to $28.0 million and $15.48, respectively, for the same period in 2024.<\/li>\n<li style=\"margin-bottom:6pt;text-align:justify\">Research and development expenses for the nine months ended September 30, 2025 were $12.1 million, compared to $17.7 million for the same period in 2024. The $5.6 million decrease was primarily due to a decrease in costs incurred as a result of re-prioritizing efforts towards exploring strategic alternatives.<\/li>\n<li style=\"text-align:justify\">General and administrative expenses for the nine months ended September 30, 2025 were $10.4 million, compared to $10.4 million for the same period in 2024, and were primarily related to employee compensation costs, inclusive of one-time separation costs for employees terminated during the nine months ended September 30, 2025, as well as consulting and professional services.<\/li>\n<\/ul>\n<p>\n        <strong>About Tempest Therapeutics<\/strong>\n      <\/p>\n<p align=\"justify\">Tempest Therapeutics is a clinical-stage biotechnology company advancing a diverse portfolio of small molecule product candidates containing tumor-targeted and\/or immune-mediated mechanisms with the potential to treat a wide range of tumors. Tempest is headquartered in Brisbane, California. More information about Tempest can be found on the company\u2019s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=E8aD1Wh50W6IELBPb5GbD1ZagufoWoumCub-ql9kQcpdkkeFgnpn1-48PmMUPqwGBu-J7FYHrC6mWCqsBoBo_tUl6XQ4MTt-vlC-95-qb3g=\" rel=\"nofollow\" target=\"_blank\"><u>www.tempesttx.com<\/u><\/a>.<\/p>\n<p>\n        <strong>Forward-Looking Statements <\/strong>\n      <\/p>\n<p align=\"justify\">This press release contains forward-looking statements (including within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended (the \u201cSecurities Act\u201d)) concerning Tempest Therapeutics, Inc. These statements may discuss goals, intentions, and expectations as to future plans, trends, events, results of operations or financial condition, or otherwise, based on current beliefs of the management of Tempest Therapeutics, as well as assumptions made by, and information currently available to, management of Tempest Therapeutics. Forward-looking statements contained in this press release include but are not limited to statements relating to Tempest Therapeutics\u2019 evaluation of strategic alternatives available to the company to maximize value for stockholders and patients and anticipated therapeutic benefit and regulatory development of Tempest Therapeutics\u2019 product candidates. Any forward-looking statements in this press release are based on Tempest Therapeutics\u2019 current expectations, estimates and projections about its industry as well as management\u2019s current beliefs and expectations of future events only as of today and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include, but are not limited to, risks relating to volatility and uncertainty in the capital markets for biotechnology companies; Tempest Therapeutics\u2019 ability to continue to operate as a going concern; availability of suitable third parties with which to conduct contemplated strategic transactions; whether we will be able to pursue a strategic transaction, or whether any transaction, if pursued, will be completed on attractive terms or at all; unexpected safety or efficacy data observed during preclinical or clinical trials; clinical trial site activation or enrollment rates that are lower than expected; changes in expected or existing competition; changes in the regulatory environment; and unexpected litigation or other disputes. These and other factors that may cause actual results to differ from those expressed or implied are discussed in greater detail in the \u201cRisk Factors\u201d section of the Company\u2019s Quarterly Report on Form 10-Q for the quarter ended September 30, 2025 and other documents filed by the Company from time to time with the Securities and Exchange Commission. Except as required by applicable law, Tempest Therapeutics undertakes no obligation to revise or update any forward-looking statement, or to make any other forward-looking statements, whether as a result of new information, future events or otherwise. These forward-looking statements should not be relied upon as representing Tempest Therapeutics\u2019 views as of any date subsequent to the date of this press release and should not be relied upon as prediction of future events. In light of the foregoing, investors are urged not to rely on any forward-looking statement in reaching any conclusion or making any investment decision about any securities of Tempest Therapeutics.<\/p>\n<p align=\"justify\">\n        \n      <\/p>\n<table align=\"center\" style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td colspan=\"8\" style=\"width:99.9104%;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>TEMPEST THERAPEUTICS, INC.<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"8\" style=\"width:99.9104%;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Consolidated Balance Sheets<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"8\" style=\"width:99.9104%;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>(in thousands)<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>September 30, 2025<\/strong>\n          <\/td>\n<td style=\"width:0.985663%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>December 31, 2024<\/strong>\n          <\/td>\n<td style=\"width:0.985663%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Assets<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">Current assets<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:67%;width:66.8459%;min-width:67%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Cash and cash equivalents<\/td>\n<td style=\"max-width:1%;width:1.07527%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:14%;width:13.9785%;min-width:14%;text-align: right;vertical-align: middle;vertical-align: bottom\">7,514<\/td>\n<td style=\"max-width:1%;width:0.985663%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:0.985663%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1.07527%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:14%;width:13.9785%;min-width:14%;text-align: right;vertical-align: middle;vertical-align: bottom\">30,268<\/td>\n<td style=\"max-width:1%;width:0.985663%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Prepaid expenses and other current assets<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">590<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">1,206<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total current assets<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">8,104<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">31,474<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">Property and equipment, net<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">681<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">886<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">Operating lease right-of-use assets<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">7,825<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">8,643<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">Other noncurrent assets<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">519<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">485<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total assets<\/td>\n<td style=\"width:1.07527%;border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"width:13.9785%;border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">17,129<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"width:13.9785%;border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">41,488<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: double black 3pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: double black 3pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Liabilities and Stockholders&#8217; Equity<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">Current liabilities<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Accounts payable<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">$<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">922<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">$<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">2,450<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Accrued expenses<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">1,353<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">2,726<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Current loan payable, net<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">&#8211;<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">6,354<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Current operating lease liabilities<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">1,147<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">869<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Accrued compensation<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">103<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">1,762<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Interest payable<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">&#8211;<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">59<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total current liabilities<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">3,525<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">14,220<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">Operating lease liabilities<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">7,258<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">8,142<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total liabilities<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">10,783<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">22,362<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: bottom\">Stockholders&#8217; equity<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"width:15.0538%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Common stock<sup>(1)<\/sup><\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">4<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">3<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Additional paid-in capital<sup>(1)<\/sup><\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">235,689<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;text-align: right;vertical-align: middle;vertical-align: bottom\">226,229<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Accumulated deficit<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(229,347<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">)<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(207,106<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total stockholders&#8217; equity<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">6,346<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">19,126<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%;vertical-align: middle;text-align: left;padding-left: 30.0px;vertical-align: bottom\">Total liabilities and stockholders&#8217; equity<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">17,129<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"width:1.07527%;border-top: solid black 1pt;border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"width:13.9785%;border-top: solid black 1pt;border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">41,488<\/td>\n<td style=\"width:0.985663%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"width:66.8459%\">\u00a0<\/td>\n<td style=\"width:1.07527%\">\u00a0<\/td>\n<td style=\"width:13.9785%\">\u00a0<\/td>\n<td style=\"width:0.985663%\">\u00a0<\/td>\n<td style=\"width:0.985663%\">\u00a0<\/td>\n<td style=\"width:1.07527%\">\u00a0<\/td>\n<td style=\"width:13.9785%\">\u00a0<\/td>\n<td style=\"width:0.985663%\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td colspan=\"8\" style=\"width:99.9104%\">\n            <sup>(1)<\/sup> Results have been adjusted to reflect the one-for-thirteen reverse stock split effected in April 2025.<\/td>\n<\/tr>\n<\/table>\n<p>\n        \n      <\/p>\n<p>\n        \n      <\/p>\n<table align=\"center\" style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td colspan=\"16\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>TEMPEST THERAPEUTICS, INC.<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"16\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Consolidated Statements of Operations<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"16\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>(in thousands, except per share amounts)<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Three months ended<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Three months ended<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Nine months ended<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Nine months ended<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>September 30, 2025<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>September 30, 2024<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>September 30, 2025<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>September 30, 2024<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Expenses:<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:33%;width:33%;min-width:33%;vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Research and development<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:14%;width:14%;min-width:14%;text-align: right;vertical-align: middle;vertical-align: bottom\">570<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:14%;width:14%;min-width:14%;text-align: right;vertical-align: middle;vertical-align: bottom\">7,557<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:14%;width:14%;min-width:14%;text-align: right;vertical-align: middle;vertical-align: bottom\">12,067<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:14%;width:14%;min-width:14%;text-align: right;vertical-align: middle;vertical-align: bottom\">17,734<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">General and administrative<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">3,027<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">2,994<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">10,431<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">10,374<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Operating loss<\/strong>\n          <\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(3,597<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(10,551<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(22,498<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(28,108<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Other income (expense), net:<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Interest expense<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">&#8211;<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">(329<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">(207<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">(1,069<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Interest and other income, net<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">86<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">324<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">464<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">1,147<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Net loss<\/strong>\n          <\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(3,511<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(10,556<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(22,241<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(28,030<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Net loss per share<\/strong><br \/>\n            <sup><br \/>\n              <strong>(1)<\/strong><br \/>\n            <\/sup>\n          <\/td>\n<td style=\"border-top: double black 3pt;border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-top: double black 3pt;border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(0.79<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: double black 3pt;border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-top: double black 3pt;border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(5.32<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: double black 3pt;border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-top: double black 3pt;border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(5.71<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: double black 3pt;border-bottom: double black 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-top: double black 3pt;border-bottom: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">(15.48<\/td>\n<td style=\"vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td colspan=\"16\" style=\"vertical-align: bottom\">\n            <sup>(1)<\/sup>Results have been adjusted to reflect the one-for-thirteen reverse stock split effected in April 2025.<strong><br \/><\/strong><\/td>\n<\/tr>\n<\/table>\n<p>\n        \n      <\/p>\n<p>\n        <strong>Investor Contacts:<\/strong>\n      <\/p>\n<p>Sylvia Wheeler<br \/>Wheelhouse Life Science Advisors<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Kl_I7SvaHss_4vkoEXkxZWqeqbDHDkky7po_52j3c1XNpJkaDpeFDQJEH3JVeO9X6SsejnHTVLdju-BJLrClOpuI-ctIV9vta100tJRniBtoJ0Mv_NW_nv4qknwM3qBJ\" rel=\"nofollow\" target=\"_blank\">swheeler@wheelhouselsa.com<\/a>\u00a0<\/p>\n<p>Aljanae Reynolds <br \/>Wheelhouse Life Science Advisors<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=MqrwClmAOcHju9OZz5-Hq0yyoxrjJCs41W4g5_tI8p6-mdZY5fFvuoOcMScToRVNm4u_IwJMPIYSLaJJuFUaRa9vc9Klo0PEFT1MMFgCRKuGvU8oF41doQPIV8QntdEU\" rel=\"nofollow\" target=\"_blank\">areynolds@wheelhouselsa.com<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTU2ODk5MSM3MjQ1MDgzIzIxODk5MzQ=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/MzdlOTMxZDItOWNlMi00ZjRhLWI3NjItMmZhMWI4OTg2MmJhLTEyMDE0ODctMjAyNS0xMS0wNS1lbg==\/tiny\/Tempest-Therapeutics.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>BRISBANE, Calif., Nov. 05, 2025 (GLOBE NEWSWIRE) &#8212; Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company with a pipeline of first-in-class1 targeted and immune-mediated therapeutics to fight cancer, today reported financial results for the quarter ended September 30, 2025 and provided a corporate update. \u201cWe are continuing our strategic alternatives process with the goal of maximizing value for stockholders,\u201d said Stephen Brady, president and chief executive officer of Tempest. \u201cIn addition, we look forward to the start of the TPST-1495 Phase 2 in collaboration with the NCI and the Cancer Prevention Clinical Trials Network and remain confident in the potential of amezalpat to transform the treatment of first-line HCC and bring meaningful benefit to patients and their families.\u201d \u2014\u2014\u2014\u2014\u2014\u2014\u00a0 &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Tempest Reports Third Quarter 2025 Financial Results and Provides Business Update&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-906091","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Tempest Reports Third Quarter 2025 Financial Results and Provides Business Update - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tempest Reports Third Quarter 2025 Financial Results and Provides Business Update - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"BRISBANE, Calif., Nov. 05, 2025 (GLOBE NEWSWIRE) &#8212; Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company with a pipeline of first-in-class1 targeted and immune-mediated therapeutics to fight cancer, today reported financial results for the quarter ended September 30, 2025 and provided a corporate update. \u201cWe are continuing our strategic alternatives process with the goal of maximizing value for stockholders,\u201d said Stephen Brady, president and chief executive officer of Tempest. \u201cIn addition, we look forward to the start of the TPST-1495 Phase 2 in collaboration with the NCI and the Cancer Prevention Clinical Trials Network and remain confident in the potential of amezalpat to transform the treatment of first-line HCC and bring meaningful benefit to patients and their families.\u201d \u2014\u2014\u2014\u2014\u2014\u2014\u00a0 &hellip; Continue reading &quot;Tempest Reports Third Quarter 2025 Financial Results and Provides Business Update&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-11-05T20:55:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTU2ODk5MSM3MjQ1MDgzIzIxODk5MzQ=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Tempest Reports Third Quarter 2025 Financial Results and Provides Business Update\",\"datePublished\":\"2025-11-05T20:55:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\\\/\"},\"wordCount\":1130,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTU2ODk5MSM3MjQ1MDgzIzIxODk5MzQ=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tempest-reports-third-quarter-2025-financial-results-and-provides-business-update\\\/\",\"name\":\"Tempest Reports Third Quarter 2025 Financial Results and Provides Business Update - 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