{"id":902590,"date":"2025-10-30T03:13:33","date_gmt":"2025-10-30T07:13:33","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/takeda-reports-first-half-fy2025-results-with-business-fundamentals-tracking-as-planned-updates-full-year-outlook-to-reflect-fx-impact-and-pipeline-impairment-on-track-for-multiple-regulatory-filin\/"},"modified":"2025-10-30T03:13:33","modified_gmt":"2025-10-30T07:13:33","slug":"takeda-reports-first-half-fy2025-results-with-business-fundamentals-tracking-as-planned-updates-full-year-outlook-to-reflect-fx-impact-and-pipeline-impairment-on-track-for-multiple-regulatory-filin","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/takeda-reports-first-half-fy2025-results-with-business-fundamentals-tracking-as-planned-updates-full-year-outlook-to-reflect-fx-impact-and-pipeline-impairment-on-track-for-multiple-regulatory-filin\/","title":{"rendered":"Takeda Reports First Half FY2025 Results, with Business Fundamentals Tracking as Planned. Updates Full Year Outlook to Reflect FX Impact and Pipeline Impairment. On Track for Multiple Regulatory Filings This Fiscal Year"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwalignl { text-align: left }\n.bwblockalignl { margin-left: 0px; margin-right: auto }\n.bwcellpmargin { margin-bottom: 0px; margin-top: 0px }\n.bwleftsingle { border-left: solid black 1pt }\n.bwlistdisc { list-style-type: disc }\n.bwpadb3 { padding-bottom: 4px }\n.bwpadl0 { padding-left: 0px }\n.bwpadl2 { padding-left: 10px }\n.bwpadr0 { padding-right: 0px }\n.bwrightsingle { border-right: solid black 1pt }\n.bwsinglebottom { border-bottom: solid black 1pt }\n.bwtablemarginb { margin-bottom: 10px }\n.bwvertalignm { vertical-align: middle }\n.bwwidth100 { width: 100% }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Takeda Reports First Half FY2025 Results, with Business Fundamentals Tracking as Planned. Updates Full Year Outlook to Reflect FX Impact and Pipeline Impairment. <\/b><b>On Track for Multiple Regulatory Filings This Fiscal Year<\/b><\/p>\n<ul class=\"bwlistdisc\">\n<li><b><i>First Half Revenue Declined 3.9% at Constant Exchange Rate (CER), -6.9% at<\/i><\/b><b><i>Actual Exchange Rates (AER),<\/i><\/b><b><i>Impacted by Generic Erosion of VYVANSE\u00ae and FX Headwind<\/i><\/b><\/li>\n<li><b><i>Core Operating Profit Declined 8.8% at CER in the First Half, Reflecting Revenue Performance and Product Mix; Impact Partially Offset by Operational Efficiencies<\/i><\/b><\/li>\n<li><b><i>First Half Reported Operating Profit (-27.7% at AER) Impacted by Impairment Losses Incurred in Q2<\/i><\/b><\/li>\n<\/ul>\n<p>\n\u00a0<\/p>\n<p>OSAKA, Japan&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nTakeda (<a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fstock-information%2F&amp;esheet=54345580&amp;newsitemid=20251029831616&amp;lan=en-US&amp;anchor=TOKYO%3A4502%2FNYSE%3ATAK&amp;index=1&amp;md5=44dbaef1daa26d3c26903ce7071da8d7\">TOKYO:4502\/NYSE:TAK<\/a>) today announced earnings results for the first half of fiscal year 2025 (six months ended Sep 30, 2025) and updated its full-year outlook.<\/p>\n<p><b>Takeda chief executive officer, Christophe Weber, commented:<br \/>\n<br \/><\/b>\u201cTakeda\u2019s fiscal year 2025 first half results are consistent with our expectations for core business progress in this year of transition to a new phase focusing on new product launches. Our updated full-year outlook reflects impairment charges associated with strategic pipeline decisions taken in Q2, as well as transactional FX.<\/p>\n<p>\n\u201cLooking ahead, our current Growth and Launch Products portfolio will continue to generate moderate growth, which will accelerate in the future with new launches. We see FY2025 as a pivotal year for Takeda with regulatory filings for rusfertide and oveporexton expected in the second half of the year, as well as Phase 3 results for zasocitinib. We continue to expand our external partnerships to enhance the depth and breadth of our R&amp;D pipeline and recently announced a global strategic partnership with Innovent Biologics to further strengthen our position in oncology.<\/p>\n<p>\n\u201cWith this momentum in our pipeline, we\u2019re confident in Takeda\u2019s ability to deliver life-transforming treatments and long-term value for patients and shareholders, and we\u2019re excited for the future.\u201d<\/p>\n<p><b>Takeda chief financial officer, Milano Furuta, commented:<br \/>\n<br \/><\/b>\u201cOur financial results for the first half of FY2025 were driven by year-over-year impact from generic erosion of VYVANSE, as anticipated. In the second half, we expect this generic erosion impact to moderate and Growth and Launch Product growth to increase. Our updated outlook for the full year reflects the effects of transactional FX fluctuations and impairment losses on intangible assets associated with the gamma delta T-cell therapy platform\u2014with strong OPEX management offsetting changes in product mix.<\/p>\n<p>\n\u201cWe are confident in our business fundamentals as we look to the second half of this transitional year for Takeda.\u201d<\/p>\n<p><b>FINANCIAL HIGHLIGHTS for FY2025 H1 Ended September 30, 2025<\/b><\/p>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl\">\n<tr>\n<td colspan=\"4\" class=\"bwpadl0 bwsinglebottom\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n(Billion yen, except percentages and per share amounts)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>FY2025 H1<\/b><\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>FY2024 H1<\/b><\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>vs. PRIOR YEAR<\/b><\/p>\n<p class=\"bwalignc bwcellpmargin\">\n(Actual % change)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nRevenue<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n2,219.5<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n2,384.0<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-6.9%<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nOperating Profit<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n253.6<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n350.6<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-27.7%<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nNet Profit<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n112.4<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n187.3<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-40.0%<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nEPS (Yen)<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n72<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n119<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-39.8%<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nOperating Cash Flow<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n593.7<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n451.3<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n+31.6%<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nAdjusted Free Cash Flow (Non-IFRS)<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n525.4<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n247.5<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n+112.3%<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwpadl0\" colspan=\"5\" rowspan=\"1\">\n<p class=\"bwcellpmargin\"><b>Core (Non-IFRS)<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td colspan=\"5\" class=\"bwpadl0 bwsinglebottom\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n(Billion yen, except percentages and per share amounts)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>FY2025 H1<\/b><\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>FY2024 H1<\/b><\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>vs. PRIOR YEAR<\/b><\/p>\n<p class=\"bwalignc bwcellpmargin\">\n(Actual % change)<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>vs. PRIOR YEAR<\/b><\/p>\n<p class=\"bwalignc bwcellpmargin\">\n(CER % change)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nRevenue<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n2,219.5<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n2,384.0<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-6.9%<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-3.9%<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nOperating Profit<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n639.2<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n719.9<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-11.2 %<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-8.8%<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl2\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\"><i>Margin<\/i><\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\"><i>28.8%<\/i><\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\"><i>30.2%<\/i><\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><i>-1.4 pp<\/i><\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n\u2015<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nNet Profit<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n438.6<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n489.1<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-10.3%<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-11.1%<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwsinglebottom bwleftsingle bwrightsingle bwpadl0\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignl bwcellpmargin\">\nEPS (Yen)<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n279<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n310<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-10.0%<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwpadb3 bwalignc bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n-10.8%<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<table cellspacing=\"0\" class=\"bwwidth100 bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwpadl0\" colspan=\"3\" rowspan=\"1\">\n<p class=\"bwcellpmargin\"><b>FY2025 Outlook<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"3\" rowspan=\"1\">\n<p class=\"bwcellpmargin\"><b>Updating Full Year Management Guidance, and Reported and Core Forecasts<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0\" colspan=\"3\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nTakeda has updated its full year outlook to reflect foreign exchange impacts and impairment charges related to the cell therapy platform.<\/p>\n<p class=\"bwcellpmargin\">\n\u00a0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\" class=\"bwpadl0 bwsinglebottom\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nFY2025 Management Guidance Core Change at CER (Non-IFRS)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom\" rowspan=\"1\" colspan=\"1\" \/>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>FY2025 ORIGINAL MANAGEMENT GUIDANCE<br \/>\n<\/b><br \/><b>(May 2025)<\/b><\/p>\n<\/td>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>FY2025 REVISED MANAGEMENT GUIDANCE<br \/>\n<\/b><br \/><b>(October 2025)<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nCore Revenue<\/p>\n<\/td>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\nBroadly flat<\/p>\n<\/td>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\nBroadly flat<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nCore Operating Profit<\/p>\n<\/td>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\nBroadly flat<\/p>\n<\/td>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\nLow-single-digit % decline<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwsinglebottom bwrightsingle\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nCore EPS (Yen)<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwpadl0 bwrightsingle\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\nBroadly flat<\/p>\n<\/td>\n<td class=\"bwsinglebottom bwpadl0 bwrightsingle\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\nLow-single-digit % decline<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<table cellspacing=\"0\" class=\"bwwidth100 bwtablemarginb bwblockalignl\">\n<tr>\n<td class=\"bwpadl0\" colspan=\"3\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\nFY2025 Reported and Core Forecasts<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\" class=\"bwpadl0 bwsinglebottom\" rowspan=\"1\">\n<p class=\"bwcellpmargin\">\n(Billion yen, except percentages and per share amounts)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom bwvertalignm\" rowspan=\"1\" colspan=\"1\" \/>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>FY2025<br \/>\n<\/b><br \/><b>ORIGINAL FORECAST<\/b><\/p>\n<p class=\"bwalignc bwcellpmargin\"><b>(May 2025)<\/b><\/p>\n<\/td>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\"><b>FY2025<\/b><\/p>\n<p class=\"bwalignc bwcellpmargin\"><b>REVISED FORECAST<\/b><\/p>\n<p class=\"bwalignc bwcellpmargin\"><b>(October 2025)<\/b><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nRevenue<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n4,530.0<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n4,500.0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nCore Revenue (Non-IFRS)<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n4,530.0<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n4,500.0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nOperating Profit<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n475.0<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n400.0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nCore Operating Profit (Non-IFRS)<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n1,140.0<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n1,130.0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nNet Profit<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n228.0<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n153.0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nEPS (Yen)<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n145<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n97<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nCore EPS (Yen) (Non-IFRS)<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n485<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwpadb3 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n479<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwrightsingle bwsinglebottom bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nAdjusted Free Cash Flow (Non-IFRS)<\/p>\n<\/td>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n750.0-850.0<\/p>\n<\/td>\n<td class=\"bwpadl0 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwalignc bwcellpmargin\">\n600.0-700.0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"bwpadl0 bwleftsingle bwsinglebottom bwrightsingle bwvertalignm\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin\">\nAnnual Dividend per Share (Yen)<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwsinglebottom bwrightsingle bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n200<\/p>\n<\/td>\n<td class=\"bwpadl0 bwpadr0 bwpadb3 bwrightsingle bwsinglebottom bwvertalignm bwalignc\" rowspan=\"1\" colspan=\"1\">\n<p class=\"bwcellpmargin bwalignc\">\n200<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p><b>Additional Information About Takeda\u2019s FY2025 H1 Results<br \/>\n<br \/><\/b>For more details about Takeda\u2019s FY2025 H1 results, commercial progress, pipeline updates and other financial information, including key assumptions in the FY2025 forecast and management guidance as well as definitions of non-IFRS measures, please refer to Takeda\u2019s FY2025 H1 investor presentation (available at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Ffinancial-results%2Fquarterly-results%2F&amp;esheet=54345580&amp;newsitemid=20251029831616&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Ffinancial-results%2Fquarterly-results%2F&amp;index=2&amp;md5=d962b3e9702006c5d567a04572d47848\">https:\/\/www.takeda.com\/investors\/financial-results\/quarterly-results\/<\/a>).<\/p>\n<p><b>About Takeda<br \/>\n<br \/><\/b>Takeda is focused on creating better health for people and a brighter future for the world. We aim to discover and deliver life-transforming treatments in our core therapeutic and business areas, including gastrointestinal and inflammation, rare diseases, plasma-derived therapies, oncology, neuroscience and vaccines. Together with our partners, we aim to improve the patient experience and advance a new frontier of treatment options through our dynamic and diverse pipeline. As a leading values-based, R&amp;D-driven biopharmaceutical company headquartered in Japan, we are guided by our commitment to patients, our people and the planet. Our employees in approximately 80 countries and regions are driven by our purpose and are grounded in the values that have defined us for more than two centuries. For more information, visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.takeda.com&amp;esheet=54345580&amp;newsitemid=20251029831616&amp;lan=en-US&amp;anchor=www.takeda.com&amp;index=3&amp;md5=f3d2cfda6a62b934a4b03aa9737d4b2a\">www.takeda.com<\/a>.<\/p>\n<p><b>Important Notice<br \/>\n<br \/><\/b>For the purposes of this notice, \u201cpress release\u201d means this document, any oral presentation, any question and answer session and any written or oral material discussed or distributed by Takeda Pharmaceutical Company Limited (\u201cTakeda\u201d) regarding this press release. This press release (including any oral briefing and any question-and-answer in connection with it) is not intended to, and does not constitute, represent or form part of any offer, invitation or solicitation of any offer to purchase, otherwise acquire, subscribe for, exchange, sell or otherwise dispose of, any securities or the solicitation of any vote or approval in any jurisdiction. No shares or other securities are being offered to the public by means of this press release. No offering of securities shall be made in the United States except pursuant to registration under the U.S. Securities Act of 1933, as amended, or an exemption therefrom. This press release is being given (together with any further information which may be provided to the recipient) on the condition that it is for use by the recipient for information purposes only (and not for the evaluation of any investment, acquisition, disposal or any other transaction). Any failure to comply with these restrictions may constitute a violation of applicable securities laws.<\/p>\n<p>\nThe companies in which Takeda directly and indirectly owns investments are separate entities. In this press release, \u201cTakeda\u201d is sometimes used for convenience where references are made to Takeda and its subsidiaries in general. Likewise, the words \u201cwe\u201d, \u201cus\u201d and \u201cour\u201d are also used to refer to subsidiaries in general or to those who work for them. These expressions are also used where no useful purpose is served by identifying the particular company or companies.<\/p>\n<p>\nThe product names appearing in this document are trademarks or registered trademarks owned by Takeda, or their respective owners.<\/p>\n<p><b>Forward-Looking Statements<br \/>\n<br \/><\/b>This press release and any materials distributed in connection with this press release may contain forward-looking statements, beliefs or opinions regarding Takeda\u2019s future business, future position and results of operations, including estimates, forecasts, targets and plans for Takeda. Without limitation, forward-looking statements often include words such as \u201ctargets\u201d, \u201cplans\u201d, \u201cbelieves\u201d, \u201chopes\u201d, \u201ccontinues\u201d, \u201cexpects\u201d, \u201caims\u201d, \u201cintends\u201d, \u201censures\u201d, \u201cwill\u201d, \u201cmay\u201d, \u201cshould\u201d, \u201cwould\u201d, \u201ccould\u201d, \u201canticipates\u201d, \u201cestimates\u201d, \u201cprojects\u201d, \u201cforecasts\u201d, \u201coutlook\u201d or similar expressions or the negative thereof. These forward-looking statements are based on assumptions about many important factors, including the following, which could cause actual results to differ materially from those expressed or implied by the forward-looking statements: the economic circumstances surrounding Takeda\u2019s global business, including general economic conditions in Japan and the United States and with respect to international trade relations; competitive pressures and developments; changes to applicable laws and regulations, including tax, tariff and other trade-related rules; challenges inherent in new product development, including uncertainty of clinical success and decisions of regulatory authorities and the timing thereof; uncertainty of commercial success for new and existing products; manufacturing difficulties or delays; fluctuations in interest and currency exchange rates; claims or concerns regarding the safety or efficacy of marketed products or product candidates; the impact of health crises, like the novel coronavirus pandemic; the success of our environmental sustainability efforts, in enabling us to reduce our greenhouse gas emissions or meet our other environmental goals; the extent to which our efforts to increase efficiency, productivity or cost-savings, such as the integration of digital technologies, including artificial intelligence, in our business or other initiatives to restructure our operations will lead to the expected benefits; and other factors identified in Takeda\u2019s most recent Annual Report on Form 20-F and Takeda\u2019s other reports filed with the U.S. Securities and Exchange Commission, available on Takeda\u2019s website at: <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fsec-filings-and-security-reports%2F&amp;esheet=54345580&amp;newsitemid=20251029831616&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Fsec-filings-and-security-reports%2F&amp;index=4&amp;md5=3def4e0c162780e8a08f12da9fa716d9\">https:\/\/www.takeda.com\/investors\/sec-filings-and-security-reports\/<\/a>or at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.sec.gov&amp;esheet=54345580&amp;newsitemid=20251029831616&amp;lan=en-US&amp;anchor=www.sec.gov&amp;index=5&amp;md5=08f35a100a78e47571ae67a049a93afb\">www.sec.gov<\/a>.Takeda does not undertake to update any of the forward-looking statements contained in this press release or any other forward-looking statements it may make, except as required by law or stock exchange rule. Past performance is not an indicator of future results and the results or statements of Takeda in this press release may not be indicative of, and are not an estimate, forecast, guarantee or projection of Takeda\u2019s future results.<\/p>\n<p><b>Financial information and Non-IFRS Measures<br \/>\n<br \/><\/b>Takeda\u2019s financial statements are prepared in accordance with International Financial Reporting Standards (\u201cIFRS\u201d).<\/p>\n<p>\nThis press release and materials distributed in connection with this press release include certain financial measures not presented in accordance with IFRS, such as Core Revenue, Core Operating Profit, Core Net Profit for the year attributable to owners of the Company, Core EPS, Constant Exchange Rate (\u201cCER\u201d) change, Net Debt, Adjusted Net Debt, EBITDA, Adjusted EBITDA, Free Cash Flow and Adjusted Free Cash Flow. Takeda\u2019s management evaluates results and makes operating and investment decisions using both IFRS and non-IFRS measures included in this press release. These non-IFRS measures exclude certain income, cost and cash flow items which are included in, or are calculated differently from, the most closely comparable measures presented in accordance with IFRS. Takeda\u2019s non-IFRS measures are not prepared in accordance with IFRS and such non-IFRS measures should be considered a supplement to, and not a substitute for, measures prepared in accordance with IFRS (which we sometimes refer to as \u201creported\u201d measures). Investors are encouraged to review the definitions and reconciliations of non-IFRS measures to their most directly comparable IFRS measures, which are in the Financial Appendix appearing at the end of our FY2025 H1 investor presentation (available at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.takeda.com%2Finvestors&amp;esheet=54345580&amp;newsitemid=20251029831616&amp;lan=en-US&amp;anchor=www.takeda.com%2Finvestors&amp;index=6&amp;md5=f17d2a93d0871644bd344a5ec0427d50\">www.takeda.com\/investors<\/a>).<\/p>\n<p><b>Medical information<br \/>\n<br \/><\/b>This press release contains information about products that may not be available in all countries, or may be available under different trademarks, for different indications, in different dosages, or in different strengths. Nothing contained herein should be considered a solicitation, promotion or advertisement for any prescription drugs including the ones under development.<\/p>\n<p>\nPlease refer to slide 7 of Takeda\u2019s FY2025 H1 investor presentation (available at\u3000<a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Ffinancial-results%2Fquarterly-results%2F&amp;esheet=54345580&amp;newsitemid=20251029831616&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.takeda.com%2Finvestors%2Ffinancial-results%2Fquarterly-results%2F&amp;index=7&amp;md5=d038ee8f643671730a23340d09a3fe8e\">https:\/\/www.takeda.com\/investors\/financial-results\/quarterly-results\/<\/a>) for the definition of Growth &amp; Launch Products.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20251029831616r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20251029831616\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20251029831616\/en\/<\/a><\/span><\/p>\n<p><b>Investor Relations<br \/>\n<\/b><br \/>Christopher O\u2019Reilly<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:christopher.oreilly@takeda.com\">Christopher.oreilly@takeda.com<br \/>\n<\/a><br \/>+81 (0) 90-6481-3412<\/p>\n<p><b>Media Relations<br \/>\n<\/b><br \/><a rel=\"nofollow\" href=\"mailto:Media_relations@takeda.com\">Media_Relations@takeda.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> United States Japan North America Asia Pacific Massachusetts<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Biotechnology Pharmaceutical Health Oncology<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20251029831616\/en\/791321\/3\/logo.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Takeda Reports First Half FY2025 Results, with Business Fundamentals Tracking as Planned. Updates Full Year Outlook to Reflect FX Impact and Pipeline Impairment. On Track for Multiple Regulatory Filings This Fiscal Year First Half Revenue Declined 3.9% at Constant Exchange Rate (CER), -6.9% atActual Exchange Rates (AER),Impacted by Generic Erosion of VYVANSE\u00ae and FX Headwind Core Operating Profit Declined 8.8% at CER in the First Half, Reflecting Revenue Performance and Product Mix; Impact Partially Offset by Operational Efficiencies First Half Reported Operating Profit (-27.7% at AER) Impacted by Impairment Losses Incurred in Q2 \u00a0 OSAKA, Japan&#8211;(BUSINESS WIRE)&#8211; Takeda (TOKYO:4502\/NYSE:TAK) today announced earnings results for the first half of fiscal year 2025 (six months ended Sep 30, 2025) and updated its &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/takeda-reports-first-half-fy2025-results-with-business-fundamentals-tracking-as-planned-updates-full-year-outlook-to-reflect-fx-impact-and-pipeline-impairment-on-track-for-multiple-regulatory-filin\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Takeda Reports First Half FY2025 Results, with Business Fundamentals Tracking as Planned. Updates Full Year Outlook to Reflect FX Impact and Pipeline Impairment. On Track for Multiple Regulatory Filings This Fiscal Year&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-902590","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Takeda Reports First Half FY2025 Results, with Business Fundamentals Tracking as Planned. Updates Full Year Outlook to Reflect FX Impact and Pipeline Impairment. On Track for Multiple Regulatory Filings This Fiscal Year - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/takeda-reports-first-half-fy2025-results-with-business-fundamentals-tracking-as-planned-updates-full-year-outlook-to-reflect-fx-impact-and-pipeline-impairment-on-track-for-multiple-regulatory-filin\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Takeda Reports First Half FY2025 Results, with Business Fundamentals Tracking as Planned. Updates Full Year Outlook to Reflect FX Impact and Pipeline Impairment. 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On Track for Multiple Regulatory Filings This Fiscal Year First Half Revenue Declined 3.9% at Constant Exchange Rate (CER), -6.9% atActual Exchange Rates (AER),Impacted by Generic Erosion of VYVANSE\u00ae and FX Headwind Core Operating Profit Declined 8.8% at CER in the First Half, Reflecting Revenue Performance and Product Mix; Impact Partially Offset by Operational Efficiencies First Half Reported Operating Profit (-27.7% at AER) Impacted by Impairment Losses Incurred in Q2 \u00a0 OSAKA, Japan&#8211;(BUSINESS WIRE)&#8211; Takeda (TOKYO:4502\/NYSE:TAK) today announced earnings results for the first half of fiscal year 2025 (six months ended Sep 30, 2025) and updated its &hellip; Continue reading &quot;Takeda Reports First Half FY2025 Results, with Business Fundamentals Tracking as Planned. Updates Full Year Outlook to Reflect FX Impact and Pipeline Impairment. 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