{"id":899991,"date":"2025-10-24T07:15:54","date_gmt":"2025-10-24T11:15:54","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/pulse-biosciences-announces-first-enrollment-in-the-nanoclamp-af-study\/"},"modified":"2025-10-24T07:15:54","modified_gmt":"2025-10-24T11:15:54","slug":"pulse-biosciences-announces-first-enrollment-in-the-nanoclamp-af-study","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/pulse-biosciences-announces-first-enrollment-in-the-nanoclamp-af-study\/","title":{"rendered":"Pulse Biosciences Announces First Enrollment in the NANOCLAMP AF Study"},"content":{"rendered":"

<\/p>\n

Pulse Biosciences Announces First Enrollment in the NANOCLAMP AF Study<\/b><\/p>\n

First U.S. Surgical Treatments with PFA Clamp for Patients with Atrial Fibrillation During Concomitant Surgical Procedure<\/i><\/p>\n

HAYWARD, Calif.–(BUSINESS WIRE<\/a>)–
\nPulse Biosciences, Inc. (Nasdaq: PLSE), a company leveraging its novel nPulse\u2122 technology using its proprietary Nanosecond Pulsed Field Ablation\u2122 (nanosecond PFA or nsPFA\u2122) energy, today announced the enrollment of the first patient in its NANOCLAMP AF Study for the treatment of atrial fibrillation (AF). The successful first procedure was completed at St. Helena Hospital in St. Helena, California, with the nPulse\u2122 Cardiac Surgical Systemfollowing its recent FDA IDE approval.<\/p>\n

\nNANOCLAMP AF is a single-arm, prospective multicenter study designed to demonstrate the safety and effectiveness of the nPulse Cardiac Surgical System for the treatment of AF in concomitant surgical procedures. Multiple sites, including two outside the United States, are planned for patient enrollment.<\/p>\n

\n\u201cAfter years of development, it is an honor to perform the first NANOCLAMP AF surgical procedure in the U.S. for the treatment of AF using nanosecond PFA with Dr. Aaron Kime and the team here at Adventist Health,\u201d said Dr. Gan Dunnington, Cardiothoracic Surgeon for Adventist Health. \u201cI\u2019m excited for my fellow surgeon colleagues to experience this technology as we aim to bring faster, safer, and more effective treatment options to patients suffering from AF. While I have seen this technology used in the European clinical experience, my team was impressed by the nPulse Cardiac Clamp\u2019s ease of use, and the speed of treatment exceeded their expectations.\u201d<\/p>\n

\n\u201cThis trial marks a pivotal moment in our journey to transform patient care. nPulse technology has the potential to revolutionize how we approach concomitant ablation procedures. This device offers an improved safety profile as a result of the nonthermal mechanism of action while enabling consistent, precise, contiguous and durable full-thickness lesions in a fraction of the time compared to existing technology. This should ultimately translate to improved outcomes for our patients and expand treatment to more people in need,\u201d said Dr. Matthew Romano, National Principal Investigator and Professor of Cardiac Surgery at the University of Michigan.<\/p>\n

\nThe nPulse\u2122 Cardiac Surgical System is a next-generation, bipolar surgical device engineered to create continuous, full-thickness ablation lines during concomitant cardiac procedures. The system utilizes a nonthermal energy modality which is expected to provide significant safety and procedural advantages over conventional thermal ablation methods. The nsPFA Cardiac Surgical System was granted FDA Breakthrough Device Designation in July 2024 and is enrolled in the FDA\u2019s Total Product Life Cycle (TPLC) Advisory Program (TAP).<\/p>\n

\n\u201cTreating our first patient so quickly following the IDE approval demonstrates the excitement about nanosecond PFA among cardiovascular surgeons,\u201d said Dr. Niv Ad, Chief Scientific Officer, Cardiac Surgery at Pulse Biosciences. \u201cProving the benefits of nsPFA in this study could drive significant future adoption of surgical cardiac ablation. We are grateful to all the clinicians who continue to support our clinical work. Together we are poised to advance the standard of care for AF and increase the number of patients being treated.\u201d<\/p>\n

About Pulse Biosciences<\/b>\u00ae<\/sup><\/p>\n

\nPulse Biosciences is a novel bioelectric medicine company committed to health innovation that has the intention as well as the potential to improve the quality of life for patients. The Company\u2019s proprietary nPulse\u2122 technology delivers nanosecond pulses of electrical energy to non-thermally clear cells while sparing adjacent noncellular tissue. The Company is actively pursuing the development of its nPulse technology for use in the treatment of atrial fibrillation and in a select few other markets where it could have a profound positive impact on healthcare for both patients and providers, such as surgical soft tissue ablation.<\/p>\n

\nPulse Biosciences, nPulse, Vybrance, CellFX, Nano-Pulse Stimulation, NPS, nsPFA, CellFX nsPFA, nanosecond PFA and the stylized logos are among the trademarks and\/or registered trademarks of Pulse Biosciences, Inc. in the United States and other countries.<\/p>\n

Forward-Looking Statements<\/b><\/p>\n

\nAll statements in this press release that are not historical are forward-looking statements, including, among other things, statements relating to whether the nPulse\u2122 Cardiac Surgical System can create continuous, full-thickness ablation lines during concomitant cardiac procedures or whether it can provide important safety and procedural advantages over conventional thermal ablation methods for treating atrial fibrillation, statements concerning the effectiveness of the Company\u2019s nPulse technology to non-thermally clear cells while sparing adjacent noncellular tissue, statements concerning the potential market opportunities for the use of nsPFA to treat AF and whether the market might grow in the future; statements concerning early clinical successes and whether they are predictive of the safety and effectiveness of any medical device, such as the nPulse Cardiac Surgical System and statements concerning the Company\u2019s future clinical and regulatory initiatives anywhere in the world, and other future events. These statements are not historical facts but rather are based on Pulse Biosciences\u2019 current expectations, estimates, and projections regarding Pulse Biosciences\u2019 business, operations and other similar or related factors. Words such as \u201cmay,\u201d \u201cwill,\u201d \u201ccould,\u201d \u201cwould,\u201d \u201cshould,\u201d \u201canticipate,\u201d \u201cpredict,\u201d \u201cpotential,\u201d \u201ccontinue,\u201d \u201cexpects,\u201d \u201cintends,\u201d \u201cplans,\u201d \u201cprojects,\u201d \u201cbelieves,\u201d \u201cestimates,\u201d and other similar or related expressions are used to identify these forward-looking statements, although not all forward-looking statements contain these words. You should not place undue reliance on forward-looking statements because they involve known and unknown risks, uncertainties, and assumptions that are difficult or impossible to predict and, in some cases, beyond Pulse Biosciences\u2019 control. Actual results may differ materially from those in the forward-looking statements as a result of a number of factors, including those described in Pulse Biosciences\u2019 filings with the Securities and Exchange Commission. Pulse Biosciences undertakes no obligation to revise or update information in this release to reflect events or circumstances in the future, even if new information becomes available.<\/p>\n

\"\"<\/p>\n

View source version on businesswire.com: <\/span>https:\/\/www.businesswire.com\/news\/home\/20251024181506\/en\/<\/a><\/span><\/p>\n

Investors:
\n<\/b>
Pulse Biosciences, Inc.
\n
Jon Skinner, CFO
\n
IR@pulsebiosciences.com<\/a><\/p>\n

Or
\n<\/b>
Gilmartin Group
\n
Philip Trip Taylor
\n
415.937.5406
\n
philip@gilmartinir.com<\/a><\/p>\n

KEYWORDS:<\/b> California United States North America<\/p>\n

INDUSTRY KEYWORDS:<\/b> Cardiology Biotechnology Other Health Health Health Technology Other Science Medical Devices Research Surgery Science Clinical Trials<\/p>\n

MEDIA:<\/b><\/p>\n\n\n\n\n
Logo<\/b><\/font><\/td>\n<\/tr>\n
\"Logo\"<\/td>\n<\/tr>\n
<\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Pulse Biosciences Announces First Enrollment in the NANOCLAMP AF Study First U.S. Surgical Treatments with PFA Clamp for Patients with Atrial Fibrillation During Concomitant Surgical Procedure HAYWARD, Calif.–(BUSINESS WIRE)– Pulse Biosciences, Inc. (Nasdaq: PLSE), a company leveraging its novel nPulse\u2122 technology using its proprietary Nanosecond Pulsed Field Ablation\u2122 (nanosecond PFA or nsPFA\u2122) energy, today announced the enrollment of the first patient in its NANOCLAMP AF Study for the treatment of atrial fibrillation (AF). The successful first procedure was completed at St. Helena Hospital in St. Helena, California, with the nPulse\u2122 Cardiac Surgical Systemfollowing its recent FDA IDE approval. NANOCLAMP AF is a single-arm, prospective multicenter study designed to demonstrate the safety and effectiveness of the nPulse Cardiac Surgical System for … <\/p>\n

Continue reading “Pulse Biosciences Announces First Enrollment in the NANOCLAMP AF Study”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-899991","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nPulse Biosciences Announces First Enrollment in the NANOCLAMP AF Study - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/pulse-biosciences-announces-first-enrollment-in-the-nanoclamp-af-study\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pulse Biosciences Announces First Enrollment in the NANOCLAMP AF Study - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Pulse Biosciences Announces First Enrollment in the NANOCLAMP AF Study First U.S. Surgical Treatments with PFA Clamp for Patients with Atrial Fibrillation During Concomitant Surgical Procedure HAYWARD, Calif.–(BUSINESS WIRE)– Pulse Biosciences, Inc. (Nasdaq: PLSE), a company leveraging its novel nPulse\u2122 technology using its proprietary Nanosecond Pulsed Field Ablation\u2122 (nanosecond PFA or nsPFA\u2122) energy, today announced the enrollment of the first patient in its NANOCLAMP AF Study for the treatment of atrial fibrillation (AF). The successful first procedure was completed at St. Helena Hospital in St. Helena, California, with the nPulse\u2122 Cardiac Surgical Systemfollowing its recent FDA IDE approval. 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