{"id":892503,"date":"2025-10-06T07:32:59","date_gmt":"2025-10-06T11:32:59","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/"},"modified":"2025-10-06T07:32:59","modified_gmt":"2025-10-06T11:32:59","slug":"maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/","title":{"rendered":"Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors"},"content":{"rendered":"<h2>\nMr. Hoppenot, a seasoned biotech leader who has driven transformative therapies to market, joins Maze to fuel its evolution into a leading clinical-stage biotech<br \/>\n<\/h2>\n<div class=\"mw_release\">\n<p align=\"left\">SOUTH SAN FRANCISCO, Calif., Oct.  06, 2025  (GLOBE NEWSWIRE) &#8212; Maze Therapeutics, Inc. (Nasdaq: MAZE), a clinical-stage biopharmaceutical company developing small molecule precision medicines for patients with kidney and metabolic diseases, today announced the appointment of Herv\u00e9 Hoppenot as Chairman of its Board of Directors, succeeding Charles Homcy, M.D., who will continue to serve on the Board.<\/p>\n<p align=\"left\">\u201cI am honored to assume the role of Chairman of the Board at this pivotal moment for Maze Therapeutics,\u201d said Mr. Hoppenot. \u201cWith encouraging first-in-human data for MZE782, an\u00a0oversubscribed $150 million private placement, and important clinical milestones ahead, including the advancement of MZE829 targeting APOL1-mediated kidney disease, Maze is well-positioned to deliver meaningful progress. The team has consistently demonstrated strong execution, and I look forward to working with them to advance therapies that can transform the lives of patients with kidney and metabolic diseases.\u201d<\/p>\n<p align=\"left\">Mr. Hoppenot brings over three decades of experience in therapeutic development and commercial leadership to the Board. He most recently served as Chief Executive Officer of Incyte Corporation from 2014 to 2025 and as Chairman of Incyte from 2015 to 2025, following his appointment to the Board of Directors in 2014. Prior to Incyte, he held senior positions at Novartis, including President of Novartis Oncology, Chief Commercial Officer, and Head of Global Product Strategy &amp; Scientific Development, as well as Senior Vice President and Head of Global Marketing for Novartis Oncology. Earlier in his career, Mr. Hoppenot advanced through a series of leadership roles at Aventis (formerly Rh\u00f4ne-Poulenc), including Vice President of U.S. Oncology. He currently serves on the boards of Incyte, Laboratoires Pierre Fabre, N-Power Medicine and Bicycle Therapeutics, and holds a degree from ESSEC Business School in France.<\/p>\n<p align=\"left\">\u201cHerv\u00e9 is a proven company builder, having transformed Incyte from a single-product company into a diversified biotech leader and driving its growth from $350 million to more than $4 billion in revenue as CEO,\u201d said Jason Coloma, Ph.D., chief executive officer of Maze. \u201cWe are honored to welcome him as Chairman as we accelerate Maze\u2019s progress toward several key milestones in 2026, including initiating Phase 2 trials in PKU and CKD for MZE782 and an initial topline Phase 2 data readout for MZE829 in APOL1-mediated kidney disease. Herv\u00e9\u2019s leadership will be invaluable as we advance transformative therapies for patients with kidney and metabolic diseases. We are also deeply grateful to Charles, a Maze co-founder, for his outstanding service as Chairman. His guidance has been instrumental in shaping our scientific foundation and clinical progress, and we are delighted he will continue to contribute as a member of our Board and R&amp;D Committee.\u201d<\/p>\n<p align=\"left\">\n        <strong>About Maze Therapeutics<\/strong><br \/>\n        <br \/>Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel small molecule precision medicines for patients with kidney and metabolic diseases. Guided by its Compass\u2122\u00a0platform, Maze pursues genetically validated targets by integrating variant discovery and functionalization to discover and advance small molecule programs with first- or best-in-class potential. Maze\u2019s pipeline is led by MZE829, a dual-mechanism APOL1 inhibitor in Phase 2 development for APOL1-mediated kidney disease (AMKD), and MZE782, a SLC6A19 inhibitor advancing to Phase 2 with the potential to treat both phenylketonuria (PKU) and chronic kidney disease (CKD). Maze is headquartered in South San Francisco. For more information, please visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=9YepZr3PN2ucmw3irwBHQswrnHUXjKYfp9FpFR1UoH-y3uh9qYcTFZYCaFUuzTdopC80iPHfEawKgSfa45QX9Z7r9U81M7mBcxlrirckz3wJU694JEG89i2z5sGOTx5xHRIbaqbGmSwYWZHGxSjQkp-1nKctPf3zdzPAxj5iKZRZ3_HcsL1Y6o71QuDgbwU728pzseZ5pc00Y7bvzsyGXOLWUXjc25CUTWPSpLH3hWQ=\" rel=\"nofollow\" target=\"_blank\"><u>mazetx.com<\/u><\/a>, or follow the company on <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=s8rCLHNgTQ0BaBHO0Xxk7fw8Iks14BwlFmSKzLHt0rSB-OeFdlr63ECQYJtRm7zZevTpjYA7-EHEuxRHrGyTj18utnQvyjwgkgSFlTX5_zJVxpsjJBsvR3TTlfHa5SHv7QWaFSE1hfyEeYnlang-hKJrCkkQ08ISO2-SgD9W_3eJ3UmEQz4v42KzYHf3gmDC_0HAsB5073CdSRTybrl9z50tpQ4b38rp2c3e-Nj7EnwyKfT7biX0rRkLM79wI0dC\" rel=\"nofollow\" target=\"_blank\"><u>LinkedIn<\/u><\/a> and <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=JJUWGDXlx3lS74wysidTfgfR0fqIh5CYL9qRFX5_j38xwDC2Y3IM-AVfcIJDxxtvFekSQX7TF8rn7AMGsMW6MDrkUs2aB8THK8I67kcv--mUZ9kaz-ASbWLwBKxXQ3RK79IVFesSU7mFPMr2DGyls8utVCfFeIUiJBbBGOwCAF-j05hrWoXXpDF233beulu6phfHIWVkdG2EXdQfgXPV1A==\" rel=\"nofollow\" target=\"_blank\"><u>X<\/u><\/a>.<\/p>\n<p align=\"left\">\n        <strong>Forward Looking Statements<\/strong><br \/>\n        <br \/>This press release contains forward-looking statements within the meaning of the \u201csafe harbor\u201d provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements reflect the current beliefs and expectations of management. All statements other than statements of historical fact are statements that could be deemed forward-looking statements, including, without limitation, statements concerning the company\u2019s future plans and prospects, any expectations regarding the safety or efficacy of MZE829, MZE782 and other candidates under development, the ability of MZE829 to treat AMKD or other indications, the ability of MZE782 to treat CKD, PKU or other indications, the planned timing of the company\u2019s clinical trials, data results and further development of MZE829, MZE782 and other therapeutic candidates, the use of proceeds from the private placement, and the ability to drive financial results and stockholder value. In addition, when or if used in this press release, the words \u201cmay,\u201d \u201ccould,\u201d \u201cshould,\u201d \u201canticipate,\u201d \u201cbelieve,\u201d \u201cestimate,\u201d \u201cexpect,\u201d \u201cintend,\u201d \u201cplan,\u201d \u201cpredict\u201d and similar expressions and their variants, as they relate to the company may identify forward-looking statements. Forward-looking statements are neither historical facts nor assurances of future performance. Although the company believes the expectations reflected in such forward-looking statements are reasonable, the company can give no assurance that such expectations will prove to be correct. Readers are cautioned that actual results, levels of activity, safety, performance or events and circumstances could differ materially from those expressed or implied in the company\u2019s forward-looking statements due to a variety of factors, including risks and uncertainties related to the company\u2019s ability to advance MZE829, MZE782 and its other therapeutic candidates, obtain regulatory approval of and ultimately commercialize the company\u2019s therapeutic candidates, the timing and results of preclinical studies and clinical trials, the company\u2019s ability to fund development activities and achieve development goals, its ability to protect its intellectual property, general business and economic conditions, and risks related to the impact on its business of macroeconomic conditions, including inflation, volatile interest rates, tariffs, instability in the global banking sector, and public health crises. Further information on potential risk factors that could affect the company\u2019s business and its financial results are detailed under the heading \u201cRisk Factors\u201d included in the documents the company files from time to time with the U.S. Securities and Exchange Commission, including the company\u2019s Annual Report on Form 10-K and Quarterly Reports on Form 10-Q. Accordingly, readers are cautioned not to place undue reliance on these forward-looking statements. These forward-looking statements speak only as of the date of this press release and the company undertakes no obligation to revise or update any forward-looking statements to reflect events or circumstances after the date hereof.<\/p>\n<p align=\"left\">\n        <strong>For further information, please contact:<\/strong><br \/>\n        <br \/>\n        <strong>IR\/Corporate Contact:<\/strong><br \/>\n        <br \/>Amy Bachrodt, Maze Therapeutics<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=24SGSo5oaKUM7TQHLsZgvYPHZYu6If4ODjFX42FVtk_vlUdQu3sORKdcNFbQF98s2fldFrU3tO7GmtxBDBYPOgFtUEtReYlAHdVcnaOrVpk=\" rel=\"nofollow\" target=\"_blank\"><u>abachrodt@mazetx.com<\/u><\/a><\/p>\n<p align=\"left\">\n        <strong>Media Contact:<\/strong><br \/>\n        <br \/>Amanda Lazaro, 1AB Media<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=gJFAZx7iRkoMvFCXXlJP0r64x2I4pO6UnEn8puWr71A1CCIatzjNQHG5altlKf_cG62i6dNB5DI78HV0WEApS1ekgEQvMJUjXpiLo6fAOWI=\" rel=\"nofollow\" target=\"_blank\"><u>Amanda@1ABMedia.com<\/u><\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTU0MDM4NiM3MTgwNDY1IzIyOTA3MzM=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/MjNjMGYzZmYtZGQyOS00YzNhLTkyYWQtODgzZWY2ZmZmODk2LTEzMDIyODMtMjAyNS0xMC0wNi1lbg==\/tiny\/Maze-Therapeutics-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Mr. Hoppenot, a seasoned biotech leader who has driven transformative therapies to market, joins Maze to fuel its evolution into a leading clinical-stage biotech SOUTH SAN FRANCISCO, Calif., Oct. 06, 2025 (GLOBE NEWSWIRE) &#8212; Maze Therapeutics, Inc. (Nasdaq: MAZE), a clinical-stage biopharmaceutical company developing small molecule precision medicines for patients with kidney and metabolic diseases, today announced the appointment of Herv\u00e9 Hoppenot as Chairman of its Board of Directors, succeeding Charles Homcy, M.D., who will continue to serve on the Board. \u201cI am honored to assume the role of Chairman of the Board at this pivotal moment for Maze Therapeutics,\u201d said Mr. Hoppenot. \u201cWith encouraging first-in-human data for MZE782, an\u00a0oversubscribed $150 million private placement, and important clinical milestones ahead, including &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-892503","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Mr. Hoppenot, a seasoned biotech leader who has driven transformative therapies to market, joins Maze to fuel its evolution into a leading clinical-stage biotech SOUTH SAN FRANCISCO, Calif., Oct. 06, 2025 (GLOBE NEWSWIRE) &#8212; Maze Therapeutics, Inc. (Nasdaq: MAZE), a clinical-stage biopharmaceutical company developing small molecule precision medicines for patients with kidney and metabolic diseases, today announced the appointment of Herv\u00e9 Hoppenot as Chairman of its Board of Directors, succeeding Charles Homcy, M.D., who will continue to serve on the Board. \u201cI am honored to assume the role of Chairman of the Board at this pivotal moment for Maze Therapeutics,\u201d said Mr. Hoppenot. \u201cWith encouraging first-in-human data for MZE782, an\u00a0oversubscribed $150 million private placement, and important clinical milestones ahead, including &hellip; Continue reading &quot;Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-06T11:32:59+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTU0MDM4NiM3MTgwNDY1IzIyOTA3MzM=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors\",\"datePublished\":\"2025-10-06T11:32:59+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\\\/\"},\"wordCount\":1063,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTU0MDM4NiM3MTgwNDY1IzIyOTA3MzM=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\\\/\",\"name\":\"Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/","og_locale":"en_US","og_type":"article","og_title":"Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors - Market Newsdesk","og_description":"Mr. Hoppenot, a seasoned biotech leader who has driven transformative therapies to market, joins Maze to fuel its evolution into a leading clinical-stage biotech SOUTH SAN FRANCISCO, Calif., Oct. 06, 2025 (GLOBE NEWSWIRE) &#8212; Maze Therapeutics, Inc. (Nasdaq: MAZE), a clinical-stage biopharmaceutical company developing small molecule precision medicines for patients with kidney and metabolic diseases, today announced the appointment of Herv\u00e9 Hoppenot as Chairman of its Board of Directors, succeeding Charles Homcy, M.D., who will continue to serve on the Board. \u201cI am honored to assume the role of Chairman of the Board at this pivotal moment for Maze Therapeutics,\u201d said Mr. Hoppenot. \u201cWith encouraging first-in-human data for MZE782, an\u00a0oversubscribed $150 million private placement, and important clinical milestones ahead, including &hellip; Continue reading \"Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/","og_site_name":"Market Newsdesk","article_published_time":"2025-10-06T11:32:59+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTU0MDM4NiM3MTgwNDY1IzIyOTA3MzM=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors","datePublished":"2025-10-06T11:32:59+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/"},"wordCount":1063,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTU0MDM4NiM3MTgwNDY1IzIyOTA3MzM=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/maze-therapeutics-appoints-industry-veteran-herve-hoppenot-as-chairman-of-the-board-of-directors\/","name":"Maze Therapeutics Appoints Industry Veteran Herv\u00e9 Hoppenot as Chairman of the Board of Directors - 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