{"id":892264,"date":"2025-10-03T09:18:24","date_gmt":"2025-10-03T13:18:24","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/"},"modified":"2025-10-03T09:18:24","modified_gmt":"2025-10-03T13:18:24","slug":"xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/","title":{"rendered":"Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"justify\">WALTHAM, Mass., Oct.  03, 2025  (GLOBE NEWSWIRE) &#8212; Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced multiple upcoming poster presentations at the Society for Immunotherapy of Cancer (SITC) 40<sup>th<\/sup> Annual Meeting, taking place from November 6-9, 2025 at the Gaylord National Convention Center in National Harbor, Maryland.<\/p>\n<p align=\"justify\">Xilio plans to present clinical data for vilastobart, a tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4, and efarindodekin alfa (XTX301), a tumor-activated IL-12, and plans to present preclinical data highlighting the company\u2019s masked T cell engager programs.<\/p>\n<p align=\"justify\">Poster presentation details, as follows:<\/p>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Title:<\/strong> ctDNA as a Potential Surrogate Biomarker for Response to Combination Vilastobart and Atezolizumab in Heavily Pretreated Microsatellite Stable (MSS) Metastatic Colorectal Cancer (mCRC)<br \/><strong>Abstract Number:<\/strong> 541<br \/><strong>Presentation Date: <\/strong>Friday, Nov. 7, 2025<br \/><strong>Poster Hall Hours:<\/strong> 9:00 a.m.-7:00 p.m. EST<br \/><strong>Location: <\/strong>Gaylord Exhibit Halls A &amp; B1<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Title: <\/strong>XTX301, a Tumor-Activated Interleukin-12 (IL-12), Demonstrated IL-12 Pharmacology in Patients with Advanced Solid Tumors: Pharmacodynamic Data from First-in-Human Phase 1 Study<br \/><strong>Abstract Number: <\/strong>567<br \/><strong>Presentation Date: <\/strong>Friday, Nov. 7, 2025<br \/><strong>Poster Hall Hours: <\/strong>9:00 a.m.-7:00 p.m. EST<br \/><strong>Location: <\/strong>Gaylord Exhibit Halls A &amp; B1<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Title:<\/strong> Masked T Cell Engagers Designed to Drive Potent Synthetic Anti-Tumor Immunity with Favorable Tolerability<br \/><strong>Abstract Number: <\/strong>972<br \/><strong>Presentation Date: <\/strong>Saturday, Nov. 8, 2025<br \/><strong>Poster Hall Hours: <\/strong>9:00 a.m.-8:40 p.m. EST<br \/><strong>Location: <\/strong>Gaylord Exhibit Halls A &amp; B1<\/li>\n<\/ul>\n<p>\n        <strong>About Xilio Therapeutics <\/strong><br \/>\n        \n      <\/p>\n<p align=\"justify\">Xilio Therapeutics is a clinical-stage biotechnology company discovering and developing tumor-activated, or masked, immuno-oncology (I-O) therapies with the goal of significantly improving outcomes for people living with cancer without the systemic side effects of current I-O treatments. The company is leveraging its proprietary platform to advance a pipeline of novel, tumor-activated I-O molecules that are designed to optimize the therapeutic index by localizing anti-tumor activity within the tumor microenvironment. Learn more by visiting\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=KmH09ZDZm9Fa8Dur2ZmAqQ1cGkK0MKZ-jGS47crx22dWL484KwSoubQezy6jPzvkhAkDZFABsutrCwMqzd_mL7x_QgLtAcoNUW4WGCsLgB6snvWtgalosQHBhPRhnFqkWpuAsNkvg0wuWJu_esV9FKW7sJsv1WQBwWfY4Ho7uVGVDJv_jQzBo8UjL2oXU4Jl_yjE9NsvhNK3rdVyzcC_ccPscvQ7Ra53qKCmsqn4N50=\" rel=\"nofollow\" target=\"_blank\"><u>www.xiliotx.com<\/u><\/a>\u00a0and follow us on LinkedIn (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=cGdeNiGMQxavzc_8aztIIHfbVaE5tXurt8VJ1r_n-jkWjt9lIrbzBAL_5meFyVs6Tn0Cj1V9oVRJYt1Q8lMkW31haKHtMcupj9DACGvBaGaHeyqAg3EH0XFflAWy0ta7OJ5fMFFNWyPJMX60f5aRB-tKtpYzdP_yvRkzJD-AwByBfdyqFiAOWsjh5qCiFfSoVy0HLZ8k7aV91BFkdnOZPR9WFsxnRIJ3bLC36oqsva7qnIxjgoQSUxY1zYH7DrN-mC39K4LSugukCOr4HShvv25x1omn2Go39V4FE-3lB2nJC3CIsNnCxnlgHdhbCEittb42S2efht0WgdLUUGWZ0g==\" rel=\"nofollow\" target=\"_blank\"><u>Xilio Therapeutics, Inc<\/u><\/a><u>.<\/u>).<\/p>\n<p>\n        <strong>Cautionary Note\u00a0Regarding Forward-Looking Statements<\/strong>\n      <\/p>\n<p align=\"justify\">This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, statements regarding plans to present data related to Xilio\u2019s clinical programs for vilastobart and efarindodekin alfa and preclinical programs for masked T cell engagers; and Xilio\u2019s strategy, goals and anticipated financial performance, milestones, business plans and focus. The words \u201caim,\u201d \u201cmay,\u201d \u201cwill,\u201d \u201ccould,\u201d \u201cwould,\u201d \u201cshould,\u201d \u201cexpect,\u201d \u201cplan,\u201d \u201canticipate,\u201d \u201cintend,\u201d \u201cbelieve,\u201d \u201cestimate,\u201d \u201cpredict,\u201d \u201cproject,\u201d \u201cpotential,\u201d \u201ccontinue,\u201d \u201cseek,\u201d \u201ctarget\u201d and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements in this press release are based on management\u2019s current expectations and beliefs and are subject to a number of important risks, uncertainties and other factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking statements contained in this press release, including, without limitation, risks related to general market conditions and geopolitical uncertainties; risks and uncertainties related to ongoing and planned research and development activities, including initiating, conducting or completing preclinical studies and clinical trials and the timing and results of such preclinical studies or clinical trials; the delay of any current or planned preclinical studies or clinical trials or the development of Xilio\u2019s current or future product candidates; Xilio\u2019s ability to obtain and maintain sufficient preclinical and clinical supply of current or future product candidates; Xilio\u2019s ability to advance multiple early stage masked T cell engager programs; initial, preliminary or interim preclinical or clinical data or results may not be replicated in or predictive of future preclinical or clinical data or results; Xilio\u2019s ability to successfully demonstrate the safety and efficacy of its product candidates and gain approval of its product candidates on a timely basis, if at all; results from preclinical studies or clinical trials for Xilio\u2019s product candidates may not support further development of such product candidates; actions of regulatory agencies may affect the initiation, timing and progress of current or future clinical trials; Xilio\u2019s ability to obtain, maintain and enforce patent and other intellectual property protection for current or future product candidates; Xilio\u2019s need to obtain additional cash resources to advance its pipeline of tumor-activated I-O molecules; the impact of international trade policies on Xilio\u2019s business, including U.S. and China trade policies; and Xilio\u2019s ability to maintain its collaboration or partnership agreements with AbbVie, Gilead and Roche. These and other risks and uncertainties are described in greater detail in the sections entitled \u201cRisk Factor Summary\u201d and \u201cRisk Factors\u201d in Xilio\u2019s filings with the U.S. Securities and Exchange Commission (\u201cSEC\u201d), including Xilio\u2019s most recent Quarterly Report on Form 10-Q and any other filings that Xilio has made or may make with the SEC in the future. Any forward-looking statements contained in this press release represent Xilio\u2019s views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date. Except as required by law, Xilio explicitly disclaims any obligation to update any forward-looking statements.<\/p>\n<p align=\"justify\">This press release contains hyperlinks to information that is not deemed to be incorporated by reference in this press release.<\/p>\n<p>TECENTRIQ is a registered trademark of Genentech USA, Inc., a member of the Roche Group.<\/p>\n<p>\n        <strong>Investor Contact\u202f\u00a0<\/strong><br \/>\n        <br \/>\n        <u><br \/>\n          <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=ygmoQen4bVAhtv8XCrWXpbsbi6wUx4LmGR1uRl4upILOSsgnXHHZbZCD5JphFbdCWDU8Olgjj0ZvGyE_IVbTccKfj9NX7ov0mNvx3kNuK_w=\" rel=\"nofollow\" target=\"_blank\">investors@xiliotx.com<\/a><br \/>\n        <\/u>\n      <\/p>\n<p>\n        <strong>Media Contact\u202f\u00a0<\/strong><br \/>\n        <br \/>Josie Butler, 1AB<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=GWPoneqIwu5km4MvrkV3uffQzJ7dHiQ64JcDxRpuaUTBTiHlEcAV_EQRnfjHtGnOGfGpu_S5MLZTgDEyPBiY86KyaoMNM9Bh450SBncFcKI=\" rel=\"nofollow\" target=\"_blank\"><u>josie@1abmedia.com<\/u><\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTUzOTM0NSM3MTc3MzQ0IzIyMDk4MDQ=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/NTcyNDczOTYtMTBlZS00ZmFlLTliYzYtMzZmZmNmYjc3NzRkLTEyMjEzNTctMjAyNS0xMC0wMy1lbg==\/tiny\/Xilio-Therapeutics-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>WALTHAM, Mass., Oct. 03, 2025 (GLOBE NEWSWIRE) &#8212; Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced multiple upcoming poster presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting, taking place from November 6-9, 2025 at the Gaylord National Convention Center in National Harbor, Maryland. Xilio plans to present clinical data for vilastobart, a tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4, and efarindodekin alfa (XTX301), a tumor-activated IL-12, and plans to present preclinical data highlighting the company\u2019s masked T cell engager programs. Poster presentation details, as follows: Title: ctDNA as a Potential Surrogate Biomarker for Response to Combination Vilastobart and Atezolizumab in Heavily Pretreated Microsatellite &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-892264","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"WALTHAM, Mass., Oct. 03, 2025 (GLOBE NEWSWIRE) &#8212; Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced multiple upcoming poster presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting, taking place from November 6-9, 2025 at the Gaylord National Convention Center in National Harbor, Maryland. Xilio plans to present clinical data for vilastobart, a tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4, and efarindodekin alfa (XTX301), a tumor-activated IL-12, and plans to present preclinical data highlighting the company\u2019s masked T cell engager programs. Poster presentation details, as follows: Title: ctDNA as a Potential Surrogate Biomarker for Response to Combination Vilastobart and Atezolizumab in Heavily Pretreated Microsatellite &hellip; Continue reading &quot;Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-03T13:18:24+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTUzOTM0NSM3MTc3MzQ0IzIyMDk4MDQ=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting\",\"datePublished\":\"2025-10-03T13:18:24+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\\\/\"},\"wordCount\":903,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTUzOTM0NSM3MTc3MzQ0IzIyMDk4MDQ=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\\\/\",\"name\":\"Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting - 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(Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced multiple upcoming poster presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting, taking place from November 6-9, 2025 at the Gaylord National Convention Center in National Harbor, Maryland. Xilio plans to present clinical data for vilastobart, a tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4, and efarindodekin alfa (XTX301), a tumor-activated IL-12, and plans to present preclinical data highlighting the company\u2019s masked T cell engager programs. Poster presentation details, as follows: Title: ctDNA as a Potential Surrogate Biomarker for Response to Combination Vilastobart and Atezolizumab in Heavily Pretreated Microsatellite &hellip; Continue reading \"Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/","og_site_name":"Market Newsdesk","article_published_time":"2025-10-03T13:18:24+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTUzOTM0NSM3MTc3MzQ0IzIyMDk4MDQ=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting","datePublished":"2025-10-03T13:18:24+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/"},"wordCount":903,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTUzOTM0NSM3MTc3MzQ0IzIyMDk4MDQ=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/xilio-therapeutics-announces-upcoming-presentations-at-the-society-for-immunotherapy-of-cancer-sitc-40th-annual-meeting\/","name":"Xilio Therapeutics Announces Upcoming Presentations at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting - 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