{"id":888449,"date":"2025-09-22T14:33:02","date_gmt":"2025-09-22T18:33:02","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/"},"modified":"2025-09-22T14:33:02","modified_gmt":"2025-09-22T18:33:02","slug":"corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/","title":{"rendered":"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwlistdisc { list-style-type: disc }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025<\/b><\/p>\n<p>REDWOOD CITY, Calif.&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nCorcept Therapeutics Incorporated (NASDAQ: CORT), a commercial-stage company engaged in the discovery and development of medications to treat severe endocrinologic, oncologic, metabolic and neurologic disorders by modulating the effects of the hormone cortisol, will present new data from its pivotal <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fir.corcept.com%2Fnews-releases%2Fnews-release-details%2Fcorcept-presents-pivotal-clinical-data-asco-late-breaker&amp;esheet=54327815&amp;newsitemid=20250922541539&amp;lan=en-US&amp;anchor=Phase+3+ROSELLA+trial&amp;index=1&amp;md5=a2e1cbec67e9a195fe6a571873cacd49\">Phase 3 ROSELLA trial<\/a> of relacorilant plus nab-paclitaxel in patients with platinum-resistant ovarian cancer at the 2025 European Society for Medical Oncology (ESMO) Annual Meeting. The data, which will be presented in a late-breaking oral presentation on Sunday, October 19, 2025, focuses on trial participants who were previously treated with a PARP inhibitor, a patient population with particularly poor prognosis.<\/p>\n<p>\nThe ROSELLA trial is being conducted in collaboration with The GOG Foundation, Inc. (GOG-F), the European Network of Gynaecological Oncological Trial groups (ENGOT), the Asia-Pacific Gynecologic Oncology Trials Group (APGOT), the Latin American Cooperative Oncology Group (LACOG) and the Australia New Zealand Gynaecological Oncology Group (ANZGOG).<\/p>\n<p><b>Presentation Details<\/b><\/p>\n<p><b>LBA45 &#8211; ROSELLA (GOG3073, ENGOTov72, APGOT-OV10): Relacorilant + Nab-paclitaxel in the Subgroup of Patients With Platinum-Resistant Ovarian Cancer (PROC) Previously Exposed to a PARP Inhibitor<\/b><\/p>\n<ul class=\"bwlistdisc\">\n<li>\nMini Oral session: Gynaecological cancers<\/p>\n<\/li>\n<li>\nOctober 19, 2025, 10:15 AM \u2013 11:45 AM CEST<\/p>\n<\/li>\n<\/ul>\n<p><b>About Relacorilant<\/b><\/p>\n<p>\nRelacorilant, an oral therapy, is a selective glucocorticoid receptor (GR) antagonist that modulates cortisol activity by binding to the GR but not to the body&#8217;s other hormone receptors. Corcept is developing relacorilant in ovarian cancer and a variety of other serious disorders, including endogenous hypercortisolism and prostate cancer. Relacorilant is proprietary to Corcept and is protected by composition of matter, method of use and other patents. It has been designated an orphan drug by the FDA and the European Commission (EC) for the treatment of hypercortisolism and by the EC for the treatment of ovarian cancer. The FDA has assigned a Prescription Drug User Fee Act (PDUFA) date of December 30, 2025 for relacorilant as a treatment for patients with hypercortisolism, and a PDUFA date of July 11, 2026 for relacorilant as a treatment for patients with platinum-resistant ovarian cancer.<\/p>\n<p><b>About Cortisol\u2019s Role in Oncology<\/b><\/p>\n<p>\nCortisol plays a role in tumor growth through several mechanisms. It helps solid tumors resist chemotherapy by inhibiting cellular apoptosis \u2014 the tumor-killing effect chemotherapy is meant to stimulate. In some cancers, cortisol promotes tumor growth by activating oncogenes in the cells to which it binds. Cortisol also suppresses the body\u2019s immune response, which weakens its ability to fight all diseases, including cancer.<\/p>\n<p><b>About Platinum-Resistant Ovarian Cancer<\/b><\/p>\n<p>\nOvarian cancer is the fifth most common cause of cancer death in women. Patients whose disease returns less than six months after receiving platinum-containing therapy have \u201cplatinum-resistant\u201d disease. There are few treatment options for these women. Median overall survival following recurrence is approximately 12 months with single-agent chemotherapy. Approximately 20,000 women with platinum-resistant disease are candidates to start a new therapy each year in the United States, with at least an equal number in Europe.<\/p>\n<p><b>About Corcept Therapeutics<\/b><\/p>\n<p>\nFor over 25 years, Corcept has focused on cortisol modulation and its potential to treat patients with a wide variety of serious disorders, leading to the discovery of more than 1,000 proprietary selective cortisol modulators and glucocorticoid receptor antagonists. Corcept is conducting advanced clinical trials in patients with hypercortisolism, solid tumors, ALS and liver disease. In February 2012, the company introduced Korlym\u00ae, the first medication approved by the U.S. Food and Drug Administration for the treatment of patients with endogenous hypercortisolism. Corcept is headquartered in Redwood City, California. For more information, visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fcorcept.com%2F&amp;esheet=54327815&amp;newsitemid=20250922541539&amp;lan=en-US&amp;anchor=Corcept.com&amp;index=2&amp;md5=e7b054d0e1748c04af5c3fa7600a7362\">Corcept.com<\/a>.<\/p>\n<p><b>Forward-Looking Statements<\/b><\/p>\n<p>\nStatements in this press release, other than statements of historical fact, are forward-looking statements based on our current plans and expectations and are subject to risks and uncertainties that might cause our actual results to differ materially from those such statements express or imply. These risks and uncertainties are set forth in our SEC filings, which are available at our website and the SEC\u2019s website.<\/p>\n<p>\nIn this press release, forward-looking statements include statements concerning the potential of relacorilant combined with nab-paclitaxel to benefit patients, as well as the timing and content of Corcept\u2019s presentation at ESMO. We disclaim any intention or duty to update forward-looking statements made in this press release.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20250922541539r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20250922541539\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20250922541539\/en\/<\/a><\/span><\/p>\n<p>\nInvestor inquiries:<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:ir@corcept.com\">ir@corcept.com<br \/>\n<\/a><br \/>Media inquiries:<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:communications@corcept.com\">communications@corcept.com<br \/>\n<\/a><br \/><a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.corcept.com%2F&amp;esheet=54327815&amp;newsitemid=20250922541539&amp;lan=en-US&amp;anchor=www.corcept.com&amp;index=3&amp;md5=6ce8a3d5ee8c64001b86d43b5e408919\">www.corcept.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> Europe United States North America California<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Research Genetics Clinical Trials Biotechnology Health Pharmaceutical General Health Science Oncology<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20250922541539\/en\/2330117\/3\/Corcept_logo_new_black.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025 REDWOOD CITY, Calif.&#8211;(BUSINESS WIRE)&#8211; Corcept Therapeutics Incorporated (NASDAQ: CORT), a commercial-stage company engaged in the discovery and development of medications to treat severe endocrinologic, oncologic, metabolic and neurologic disorders by modulating the effects of the hormone cortisol, will present new data from its pivotal Phase 3 ROSELLA trial of relacorilant plus nab-paclitaxel in patients with platinum-resistant ovarian cancer at the 2025 European Society for Medical Oncology (ESMO) Annual Meeting. The data, which will be presented in a late-breaking oral presentation on Sunday, October 19, 2025, focuses on trial participants who were previously treated with a PARP inhibitor, a patient population with &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-888449","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025 - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025 - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025 REDWOOD CITY, Calif.&#8211;(BUSINESS WIRE)&#8211; Corcept Therapeutics Incorporated (NASDAQ: CORT), a commercial-stage company engaged in the discovery and development of medications to treat severe endocrinologic, oncologic, metabolic and neurologic disorders by modulating the effects of the hormone cortisol, will present new data from its pivotal Phase 3 ROSELLA trial of relacorilant plus nab-paclitaxel in patients with platinum-resistant ovarian cancer at the 2025 European Society for Medical Oncology (ESMO) Annual Meeting. The data, which will be presented in a late-breaking oral presentation on Sunday, October 19, 2025, focuses on trial participants who were previously treated with a PARP inhibitor, a patient population with &hellip; Continue reading &quot;Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-22T18:33:02+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20250922541539r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025\",\"datePublished\":\"2025-09-22T18:33:02+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\\\/\"},\"wordCount\":762,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20250922541539r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\\\/\",\"name\":\"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025 - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/","og_locale":"en_US","og_type":"article","og_title":"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025 - Market Newsdesk","og_description":"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025 REDWOOD CITY, Calif.&#8211;(BUSINESS WIRE)&#8211; Corcept Therapeutics Incorporated (NASDAQ: CORT), a commercial-stage company engaged in the discovery and development of medications to treat severe endocrinologic, oncologic, metabolic and neurologic disorders by modulating the effects of the hormone cortisol, will present new data from its pivotal Phase 3 ROSELLA trial of relacorilant plus nab-paclitaxel in patients with platinum-resistant ovarian cancer at the 2025 European Society for Medical Oncology (ESMO) Annual Meeting. The data, which will be presented in a late-breaking oral presentation on Sunday, October 19, 2025, focuses on trial participants who were previously treated with a PARP inhibitor, a patient population with &hellip; Continue reading \"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/","og_site_name":"Market Newsdesk","article_published_time":"2025-09-22T18:33:02+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20250922541539r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025","datePublished":"2025-09-22T18:33:02+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/"},"wordCount":762,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20250922541539r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/corcept-to-present-new-late-breaking-data-from-pivotal-rosella-trial-of-relacorilant-in-platinum-resistant-ovarian-cancer-at-esmo-2025\/","name":"Corcept to Present New Late-Breaking Data From Pivotal ROSELLA Trial of Relacorilant in Platinum-Resistant Ovarian Cancer at ESMO 2025 - 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