{"id":881435,"date":"2025-09-03T09:09:09","date_gmt":"2025-09-03T13:09:09","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-enhances-cell-therapy-flex-platform-through-collaboration-with-akadeum-life-sciences\/"},"modified":"2025-09-03T09:09:09","modified_gmt":"2025-09-03T13:09:09","slug":"charles-river-enhances-cell-therapy-flex-platform-through-collaboration-with-akadeum-life-sciences","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-enhances-cell-therapy-flex-platform-through-collaboration-with-akadeum-life-sciences\/","title":{"rendered":"Charles River Enhances Cell Therapy Flex Platform through Collaboration with Akadeum Life Sciences"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwmarginl1 { margin-left: 30px }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Charles River Enhances Cell Therapy Flex Platform through Collaboration with Akadeum Life Sciences<\/b><\/p>\n<p class=\"bwalignc\"><i>Partnership aimed at improving cell separation and increasing cell viability<\/i><\/p>\n<p>WILMINGTON, Mass.&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nCharles River Laboratories International, Inc. (NYSE: CRL) and Akadeum Life Sciences, a leader in advanced cell separation technologies, announced today the integration of Akadeum\u2019s GMP-grade Human T Cell Leukopak Isolation Kit into Charles River\u2019s Cell Therapy Flex Program.<\/p>\n<p>\nCharles River\u2019s <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fbit.ly%2F4f2gkJY&amp;esheet=54317265&amp;newsitemid=20250903202682&amp;lan=en-US&amp;anchor=Cell+Therapy+Flex+Platform&amp;index=1&amp;md5=d5c131db3b81580a4729b2cbf470367b\">Cell Therapy Flex Platform <\/a>originated as an off-the-shelf solution for Cell Therapy Process Development, providing ready-to-use platforms and protocols validated for autologous CAR-T and TCR-T cell therapies to minimize risk, lower costs, and accelerate development timelines. Automated platforms with closed systems include protocols from cell selection and expansion to electroporation and viral vector methods, wash\/concentration, and fill and finish.<\/p>\n<p>\n\u201cAkadeum\u2019s Microbubble technology provides an innovative solution for cell separation, utilizing gravity to isolate T cells. This method is scalable and GMP, ensuring efficiency and quicker delivery to patients,\u201d said Kerstin Dolph, Corporate Senior Vice President, Global Manufacturing, Charles River.<\/p>\n<p>\nAkadeum\u2019s Human T Cell Leukopak Isolation Kit-GMP presents a significant advancement in cell separation with its patented Microbubble technology. Leveraging buoyancy, microbubbles effectively float unwanted cells to the surface, enhancing cell viability. The kit can be used without the need for capital investment in new equipment or extra laboratory space. Procedures can be performed directly in the apheresis bag provided within the kit, making the process simple and easy to use.<\/p>\n<p>\n\u201cCell therapy is transforming medicine, but the economics of manufacturing remain a major barrier. Our work with Charles River and the Flex platform allows us to tackle these challenges head-on, delivering healthier cells, faster processing times, and scalable separations that reduce complexity,\u201d said Brandon McNaughton, CEO of Akadeum.<\/p>\n<p><b>Cell and Gene Therapy CDMO Solutions<\/b><\/p>\n<p>\nCharles River\u2019s Cell Therapy Flex Platform continues to evolve. Earlier this year, Charles River announced the integration of Akron Bio\u2019s Closed System Solutions (CSS)\u2122 line of liquid cytokines, produced under current good manufacturing practices (CGMP), into the platform. This addition further streamlines operations, reduces risk, and enhances process robustness. Additionally, Charles River now incorporates an extra cell separation capability to boost cell viability for future drug products.<\/p>\n<p class=\"bwmarginl1\"><i>Charles River and Akadeum Life Sciences recently hosted a webinar on the evolution of Charles River\u2019s cell therapy workflow, now including Akadeum\u2019s Microbubble technology in CAR-T therapies to boost efficiency, reduce complexity, and improve outcomes while using existing resources. View the recording here: <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fbit.ly%2F4n8Slxt&amp;esheet=54317265&amp;newsitemid=20250903202682&amp;lan=en-US&amp;anchor=https%3A%2F%2Fbit.ly%2F4n8Slxt&amp;index=2&amp;md5=0af7f59daa38dfcde462bee0ef692cc3\">https:\/\/bit.ly\/4n8Slxt<\/a><\/i><\/p>\n<p><b>About Charles River<br \/>\n<br \/><\/b>Charles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. To learn more about our unique portfolio and breadth of services, visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.criver.com&amp;esheet=54317265&amp;newsitemid=20250903202682&amp;lan=en-US&amp;anchor=www.criver.com&amp;index=3&amp;md5=2a146b23c12181b1872adea41ad3663f\">www.criver.com<\/a>.<\/p>\n<p><b>About Akadeum Life Sciences<br \/>\n<br \/><\/b>Akadeum Life Sciences is dedicated to advancing cell separation technology through its unique buoyant microbubble platform, enabling researchers and manufacturers to achieve higher yields, better purity, and improved process simplicity across a range of life science applications. Our mission is to create separation technologies to advance human health. We envision a world where innovative separations empower researchers and clinicians to unlock breakthroughs in diagnostics, therapeutics, and basic research. For more information, visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.akadeum.com%2F&amp;esheet=54317265&amp;newsitemid=20250903202682&amp;lan=en-US&amp;anchor=www.akadeum.com&amp;index=4&amp;md5=51180304172d7267ae85fdd46ae67d2b\">www.akadeum.com<\/a>.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20250903202682r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20250903202682\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20250903202682\/en\/<\/a><\/span><\/p>\n<p><b>Charles River Investor Contact:<br \/>\n<\/b><br \/>Todd Spencer<br \/>\n<br \/>Corporate Vice President,<br \/>\n<br \/>Investor Relations<br \/>\n<br \/>781.222.6455<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:todd.spencer@crl.com\">todd.spencer@crl.com<br \/>\n<\/a><\/p>\n<p><b>Charles River Media Contact:<br \/>\n<\/b><br \/>Amy Cianciaruso<br \/>\n<br \/>Corporate Vice President,<br \/>\n<br \/>Chief Communications Officer<br \/>\n<br \/>781.222.6168<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:amy.cianciaruso@crl.com\">amy.cianciaruso@crl.com<br \/>\n<\/a><\/p>\n<p><b>Akadeum Life Sciences Contact:<br \/>\n<\/b><br \/>Brandon McNaughton, PhD<br \/>\n<br \/>Chief Executive Officer<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:info@akadeum.com\">info@akadeum.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> United States North America Massachusetts<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Science Biotechnology Research Pharmaceutical General Health Health Medical Devices Health Technology<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20250903202682\/en\/836653\/3\/charles_river_logo.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Charles River Enhances Cell Therapy Flex Platform through Collaboration with Akadeum Life Sciences Partnership aimed at improving cell separation and increasing cell viability WILMINGTON, Mass.&#8211;(BUSINESS WIRE)&#8211; Charles River Laboratories International, Inc. (NYSE: CRL) and Akadeum Life Sciences, a leader in advanced cell separation technologies, announced today the integration of Akadeum\u2019s GMP-grade Human T Cell Leukopak Isolation Kit into Charles River\u2019s Cell Therapy Flex Program. Charles River\u2019s Cell Therapy Flex Platform originated as an off-the-shelf solution for Cell Therapy Process Development, providing ready-to-use platforms and protocols validated for autologous CAR-T and TCR-T cell therapies to minimize risk, lower costs, and accelerate development timelines. Automated platforms with closed systems include protocols from cell selection and expansion to electroporation and viral vector methods, &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-enhances-cell-therapy-flex-platform-through-collaboration-with-akadeum-life-sciences\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Charles River Enhances Cell Therapy Flex Platform through Collaboration with Akadeum Life Sciences&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-881435","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Charles River Enhances Cell Therapy Flex Platform through Collaboration with Akadeum Life Sciences - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/charles-river-enhances-cell-therapy-flex-platform-through-collaboration-with-akadeum-life-sciences\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Charles River Enhances Cell Therapy Flex Platform through Collaboration with Akadeum Life Sciences - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Charles River Enhances Cell Therapy Flex Platform through Collaboration with Akadeum Life Sciences Partnership aimed at improving cell separation and increasing cell viability WILMINGTON, Mass.&#8211;(BUSINESS WIRE)&#8211; Charles River Laboratories International, Inc. (NYSE: CRL) and Akadeum Life Sciences, a leader in advanced cell separation technologies, announced today the integration of Akadeum\u2019s GMP-grade Human T Cell Leukopak Isolation Kit into Charles River\u2019s Cell Therapy Flex Program. Charles River\u2019s Cell Therapy Flex Platform originated as an off-the-shelf solution for Cell Therapy Process Development, providing ready-to-use platforms and protocols validated for autologous CAR-T and TCR-T cell therapies to minimize risk, lower costs, and accelerate development timelines. 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(NYSE: CRL) and Akadeum Life Sciences, a leader in advanced cell separation technologies, announced today the integration of Akadeum\u2019s GMP-grade Human T Cell Leukopak Isolation Kit into Charles River\u2019s Cell Therapy Flex Program. Charles River\u2019s Cell Therapy Flex Platform originated as an off-the-shelf solution for Cell Therapy Process Development, providing ready-to-use platforms and protocols validated for autologous CAR-T and TCR-T cell therapies to minimize risk, lower costs, and accelerate development timelines. 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