{"id":863593,"date":"2025-06-25T08:56:55","date_gmt":"2025-06-25T12:56:55","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/"},"modified":"2025-06-25T08:56:55","modified_gmt":"2025-06-25T12:56:55","slug":"evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/","title":{"rendered":"Evaxion expands R&amp;D pipeline with new vaccine program targeting Group A Streptococcus"},"content":{"rendered":"<div class=\"mw_release\">\n<ul>\n<li>\n          <b>Initial computational analysis demonstrated that Evaxion\u2019s AI-Immunology\u2122 platform can identify novel vaccine targets to combat<\/b><br \/>\n          <b>Group A <\/b><br \/>\n          <b><br \/>\n            <i>Streptococcus<\/i><br \/>\n          <\/b><br \/>\n          <b> (GAS)<\/b>\n        <\/li>\n<li style=\"text-align:justify\">\n          <b>New vaccine program is added to Evaxion\u2019s pipeline under the name EVX-B4<\/b>\n        <\/li>\n<li style=\"text-align:justify\">\n          <b>Urgent need for preventive measures against GAS underscores the significant medical and commercial potential of EVX-B4<\/b>\n        <\/li>\n<li style=\"text-align:justify\">\n          <b>Addition of a novel infectious disease candidate to the pipeline is in line with Evaxion\u2019s partnership strategy<\/b>\n        <\/li>\n<\/ul>\n<p align=\"justify\">COPENHAGEN, Denmark, June 25, 2025 &#8211; Evaxion A\/S (NASDAQ: EVAX) (\u201cEvaxion\u201d), a clinical-stage TechBio company specializing in developing AI-Immunology\u2122 powered vaccines, initiates work to develop a new preventive vaccine against Group A <i>Streptococcus<\/i> (GAS), a bacteria causing hundreds of millions of infections globally each year. Infection carries the risk of several complications including life threatening conditions like rheumatic heart disease and necrotizing fasciitis (\u201cflesh eating bacteria\u201d) and less severe yet serious diseases like strep throat and scarlet fever.<\/p>\n<p align=\"justify\">The new vaccine program, named EVX-B4, has been added to Evaxion\u2019s research &amp; development (R&amp;D) pipeline of cancer and infectious disease vaccine candidates. Initial computational analysis demonstrated that AI-Immunology\u2122 can identify novel vaccine targets to combat GAS, which could pave the way for a new approach to fight the bacteria. Deploying AI-Immunology\u2122 allows for fast and effective target discovery, design and validation, accelerating preclinical development of EVX-B4. This work will create a comprehensive preclinical data package to facilitate partnership discussions.<\/p>\n<p align=\"justify\">\u201cWe are excited to add EVX-B4 to our R&amp;D pipeline following an extensive evaluation of numerous bacterial pathogens causing severe medical complications, and for which no preventive vaccine exists. With guidance from a panel of world-renowned experts, we prioritized GAS as a key target where our AI-Immunology\u2122 platform could provide substantial benefit. The urgent need for options to prevent GAS infections is huge, underscoring the significant medical and commercial potential of EVX-B4 as well as multiple partnering options,\u201d says Birgitte R\u00f8n\u00f8, CSO of Evaxion.<\/p>\n<p align=\"justify\">Adding EVX-B4 to the pipeline achieves another of Evaxion\u2019s milestones for 2025. Evaxion\u2019s R&amp;D pipeline now comprises five specified vaccine candidates for infectious diseases and three for cancer. The build-up of the pipeline supports Evaxion\u2019s partnership strategy as we increase the number of assets for out-licensing.<\/p>\n<p align=\"justify\">\n        <b>About GAS<\/b><br \/>\n        <br \/>Group A <i>Streptococcus<\/i> (GAS) can cause a wide range of conditions ranging from life-threatening to mild depending on the severity of infection. Invasive GAS infections can cause diseases like sepsis, toxic shock, rheumatic heart disease and necrotizing fasciitis (\u201cflesh eating bacteria\u201d), all of which can be fatal if not treated immediately.<\/p>\n<p align=\"justify\">The U.S. rates of invasive GAS disease began increasing in 2014. The increase was largest among adults aged 18 through 64 years, but the rate also increased among older adults. Annually, 20,000 to 27,000 cases and 1,800 to 2,400 deaths are estimated in the US.<\/p>\n<p align=\"justify\">Worldwide, rheumatic heart disease remains a significant cause of cardiovascular disease and death. The World Health Organization estimates 470,000 new cases of acute rheumatic fever and 282,000 new cases of rheumatic heart disease each year. In 2015, there was an estimated 33.4 million cases of rheumatic heart disease. In addition, over 300,000 people die each year from rheumatic heart disease or its complications.<\/p>\n<p align=\"justify\">The number of non-invasive GAS infections, which can cause diseases like strep throat (pharyngitis), scarlet fever and impetigo, are estimated to be much higher. The World Health Organization estimates that each year over 100 million children worldwide have impetigo and over 600 million have pharyngitis due to GAS. (Source: <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=fxDG0CSaJtgZipZjXYnZzdgo6hJhI4fa04vVk1Pd4Y1V8QBf8QcK1PPRWzoSBSV_VJF5IXFGwUqTDYAb0UCup6RMPuoQmmwoTHh4zoRS_mItusgzK7gCYZM8mlOKjA02I9EX49Ui85yzpdlVQ59N_LGZ0QAuU86K4xYyv2Ar7MLxKBfxEy6Z7yQ-fZom8LWB\" rel=\"nofollow\" target=\"_blank\">The US Centers for Disease Control and Prevention<\/a>).<\/p>\n<p align=\"justify\">\n        <b>Contact information<\/b>\u00a0<br \/>Evaxion A\/S<br \/>Mads Kronborg<br \/>Vice President, Investor Relations &amp; Communication<br \/>+45 53 54 82 96 <br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=8lxs7TP4mOVE_yGbnSo95N2LRTRAxQdg8SQwoBt4dWhnuzpENJyRPUkfuh0fjBh1TE8md-qy0y8lOzSFbEULbA==\" rel=\"nofollow\" target=\"_blank\">mak@evaxion.ai<\/a><\/p>\n<p align=\"justify\">\n        <b>About Evaxion<\/b><br \/>\n        <br \/>Evaxion is a pioneering TechBio company based upon its AI platform, AI-Immunology\u2122. Evaxion\u2019s proprietary and scalable AI prediction models harness the power of artificial intelligence to decode the human immune system and develop novel immunotherapies for cancer, bacterial diseases, and viral infections. Based upon AI-Immunology\u2122, Evaxion has developed a clinical-stage oncology pipeline of novel personalized vaccines and a preclinical infectious disease pipeline in bacterial and viral diseases with high unmet medical needs. Evaxion is committed to transforming patients\u2019 lives by providing innovative and targeted treatment options. For more information about Evaxion and its groundbreaking AI-Immunology\u2122 platform and vaccine pipeline, please <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=NZFiWLtZ7-5HCipzxG31dsZHkywbC5vxy6F8q53omq1W8qtO3vnlK6c0iFoX7PfeOQCJXBKVTL-UzYtIdBnn-RDdPhPrM3XZs1DdFZzoJjA=\" rel=\"nofollow\" target=\"_blank\">visit our website<\/a>.<\/p>\n<p align=\"justify\">\n        <b>Forward-looking statement<\/b>\u00a0<br \/>This\u00a0announcement contains forward-looking statements\u00a0within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended.\u00a0The words\u00a0\u201ctarget,\u201d \u201cbelieve,\u201d \u201cexpect,\u201d \u201chope,\u201d \u201caim,\u201d \u201cintend,\u201d \u201cmay,\u201d \u201cmight,\u201d \u201canticipate,\u201d \u201ccontemplate,\u201d \u201ccontinue,\u201d \u201cestimate,\u201d \u201cplan,\u201d \u201cpotential,\u201d \u201cpredict,\u201d \u201cproject,\u201d \u201cwill,\u201d \u201ccan have,\u201d \u201clikely,\u201d \u201cshould,\u201d \u201cwould,\u201d \u201ccould,\u201d and other words and terms of similar meaning\u00a0identify forward-looking statements.\u00a0Actual results may differ materially from those indicated by such forward-looking statements as a result of various factors, including, but not limited to, risks related to: our financial condition and need for additional capital; our development work; cost and success of our product development activities and preclinical and clinical trials; commercializing any approved pharmaceutical product developed using our AI platform technology, including the rate and degree of market acceptance of our product candidates; our dependence on third parties including for conduct of clinical testing and product manufacture; our inability to enter into partnerships; government regulation; protection of our intellectual property rights; employee matters and managing growth; our ADSs and ordinary shares,\u00a0the impact of international economic, political, legal, compliance, social and business factors, including inflation, and the effects on our\u00a0business from other significant geopolitical and macro-economic events;\u00a0and other uncertainties affecting our business operations and financial condition.\u00a0For a further discussion of these risks, please refer to the risk factors included in our most recent Annual Report on Form 20-F\u00a0and other filings\u00a0with the US Securities and Exchange Commission (SEC), which are available at\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=2T0iUbKv_8zuMLsQO9a5p6JLFOYKEVnnXkCcHl6w0jMgDAjoYvhf_WhMqdQF84Vl3D9-jJY_SFxIFtcNU1jwhS4R8mKfAAZotiVOtjeuUMsPIADWPc_0O_pgrEzKLcWIVZqhPS8plGimyw4YLivYrZ1RTLc26PwTCeFRTTGyGQY3SOfks1b01fGlK7nWfgle6gbXeiKKH4Inn3feIFY19Va_QxcmtY6THFOPwVSeRJE=\" rel=\"nofollow\" target=\"_blank\"><b>www.sec.gov<\/b><\/a>.\u00a0We do not assume any obligation to update any forward-looking statements except as required by law.\u00a0<\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=MTAwMTExNDY1MCM0MDIxNzQxODMjMjI1MjA4Nw==\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml-eu.globenewswire.com\/media\/YjE1YmEzYmEtNWFmYS00YTJiLWE3ODktY2M3NWEwNWIzYWQ3LTEyNjM2NDAtMjAyNS0wNi0yNS1lbg==\/tiny\/Evaxion-Biotech.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Initial computational analysis demonstrated that Evaxion\u2019s AI-Immunology\u2122 platform can identify novel vaccine targets to combat Group A Streptococcus (GAS) New vaccine program is added to Evaxion\u2019s pipeline under the name EVX-B4 Urgent need for preventive measures against GAS underscores the significant medical and commercial potential of EVX-B4 Addition of a novel infectious disease candidate to the pipeline is in line with Evaxion\u2019s partnership strategy COPENHAGEN, Denmark, June 25, 2025 &#8211; Evaxion A\/S (NASDAQ: EVAX) (\u201cEvaxion\u201d), a clinical-stage TechBio company specializing in developing AI-Immunology\u2122 powered vaccines, initiates work to develop a new preventive vaccine against Group A Streptococcus (GAS), a bacteria causing hundreds of millions of infections globally each year. Infection carries the risk of several complications including life threatening conditions &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Evaxion expands R&amp;D pipeline with new vaccine program targeting Group A Streptococcus&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-863593","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Evaxion expands R&amp;D pipeline with new vaccine program targeting Group A Streptococcus - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Evaxion expands R&amp;D pipeline with new vaccine program targeting Group A Streptococcus - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Initial computational analysis demonstrated that Evaxion\u2019s AI-Immunology\u2122 platform can identify novel vaccine targets to combat Group A Streptococcus (GAS) New vaccine program is added to Evaxion\u2019s pipeline under the name EVX-B4 Urgent need for preventive measures against GAS underscores the significant medical and commercial potential of EVX-B4 Addition of a novel infectious disease candidate to the pipeline is in line with Evaxion\u2019s partnership strategy COPENHAGEN, Denmark, June 25, 2025 &#8211; Evaxion A\/S (NASDAQ: EVAX) (\u201cEvaxion\u201d), a clinical-stage TechBio company specializing in developing AI-Immunology\u2122 powered vaccines, initiates work to develop a new preventive vaccine against Group A Streptococcus (GAS), a bacteria causing hundreds of millions of infections globally each year. 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/","og_locale":"en_US","og_type":"article","og_title":"Evaxion expands R&amp;D pipeline with new vaccine program targeting Group A Streptococcus - Market Newsdesk","og_description":"Initial computational analysis demonstrated that Evaxion\u2019s AI-Immunology\u2122 platform can identify novel vaccine targets to combat Group A Streptococcus (GAS) New vaccine program is added to Evaxion\u2019s pipeline under the name EVX-B4 Urgent need for preventive measures against GAS underscores the significant medical and commercial potential of EVX-B4 Addition of a novel infectious disease candidate to the pipeline is in line with Evaxion\u2019s partnership strategy COPENHAGEN, Denmark, June 25, 2025 &#8211; Evaxion A\/S (NASDAQ: EVAX) (\u201cEvaxion\u201d), a clinical-stage TechBio company specializing in developing AI-Immunology\u2122 powered vaccines, initiates work to develop a new preventive vaccine against Group A Streptococcus (GAS), a bacteria causing hundreds of millions of infections globally each year. Infection carries the risk of several complications including life threatening conditions &hellip; Continue reading \"Evaxion expands R&amp;D pipeline with new vaccine program targeting Group A Streptococcus\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/","og_site_name":"Market Newsdesk","article_published_time":"2025-06-25T12:56:55+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=MTAwMTExNDY1MCM0MDIxNzQxODMjMjI1MjA4Nw==","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Evaxion expands R&amp;D pipeline with new vaccine program targeting Group A Streptococcus","datePublished":"2025-06-25T12:56:55+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/"},"wordCount":975,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=MTAwMTExNDY1MCM0MDIxNzQxODMjMjI1MjA4Nw==","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/evaxion-expands-rd-pipeline-with-new-vaccine-program-targeting-group-a-streptococcus\/","name":"Evaxion expands R&amp;D pipeline with new vaccine program targeting Group A Streptococcus - 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