{"id":859382,"date":"2025-06-11T07:03:33","date_gmt":"2025-06-11T11:03:33","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/"},"modified":"2025-06-11T07:03:33","modified_gmt":"2025-06-11T11:03:33","slug":"axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/","title":{"rendered":"Axsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025"},"content":{"rendered":"
\n

NEW YORK, June 11, 2025 (GLOBE NEWSWIRE) — Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today announced seven presentations, including two featured oral plenary sessions, on AXS-12 and solriamfetol, at SLEEP 2025, the 39th annual meeting of the\u00a0Associated Professional Sleep Societies (APSS), being held\u00a0June 8-11, 2025, in\u00a0Seattle, Washington.<\/p>\n

Details for the presentations are as follows:<\/p>\n

\n
\n AXS-12<\/em>
\n <\/strong>\n <\/p>\n

\n Title<\/strong>: ENCORE: Topline Results of a Phase 3 Open-Label Extension and Randomized-Withdrawal Trial of AXS-12 in Narcolepsy
Lead Author: <\/strong>Richard Bogan, MD, FCCP, FAASM, Associate Clinical Professor at the University of South Carolina School of Medicine in Columbia, SC
Poster Presentation Date and Time: <\/strong>Wednesday, June 11, 10 – 11:45 a.m. PT
Poster Session:<\/strong> P-51\u00a0 \u00a0 \u00a0 \u00a0\u00a0
Poster Number: <\/strong>405<\/p>\n

\n Title:<\/strong>\u00a0Impact of AXS-12 on Symptom Severity and Functional Impairment in Narcolepsy: Results from the Phase 3 SYMPHONY Trial\u00a0
Lead Author: <\/strong>Michael Thorpy, MD, Director of the Sleep-Wake Disorders Center at the Montefiore Medical Center and Professor of Neurology at Albert Einstein College of Medicine, New York, NY
Oral Presentation Date and Time:<\/strong> Wednesday, June 11, 3:45 – 4 p.m. PT
Oral Session: <\/strong>O-24
Poster Presentation Date and Time: <\/strong>Wednesday, June 11, 10 – 11:45 a.m. PT
Poster Session:<\/strong> P-51\u00a0 \u00a0 \u00a0 \u00a0\u00a0
Poster Number: <\/strong>390<\/p>\n

\n Title:<\/strong>\u00a0Residual Symptom Burden in Patients with Narcolepsy Satisfied with Treatment: Subgroup Analysis from the CRESCENDO Survey
Lead Author: <\/strong>Michael Thorpy, MD, Director of the Sleep-Wake Disorders Center at the Montefiore Medical Center and Professor of Neurology at Albert Einstein College of Medicine, New York, NY
Oral Presentation Date and Time:<\/strong> Wednesday, June 11, 4 – 4:15 p.m. PT
Oral Session: <\/strong>O-24
Poster Presentation Date and Time: <\/strong>Wednesday, June 11, 10 – 11:45 a.m. PT
Poster Session:<\/strong> P-51\u00a0 \u00a0 \u00a0 \u00a0\u00a0
Poster Number: <\/strong>391<\/p>\n

\n
\n Solriamfetol<\/em>
\n <\/strong>\n <\/p>\n

\n Title<\/strong>: Effects of Solriamfetol on Neuropsychological Outcomes in Patients with Obstructive Sleep Apnea in the Real-World SURWEY Study
Lead Author: <\/strong>Yaroslav Winter, MD, Mainz Comprehensive Epilepsy and Sleep Medicine Center,\u00a0Department of Neurology, Johannes Gutenberg-University, Mainz,\u00a0Germany
Poster Presentation Date and Time: <\/strong>Wednesday, June 11, 10 – 11:45 a.m. PT
Poster Session:<\/strong> P-50\u00a0 \u00a0 \u00a0 \u00a0\u00a0
Poster Number: <\/strong>366<\/p>\n

\n Title<\/strong>: Real-World Use of Solriamfetol for Excessive Daytime Sleepiness in Patients with Obstructive Sleep Apnea in the US
Lead Author: <\/strong>Yang Zhao, PhD, Axsome Therapeutics
Poster Presentation Date and Time: <\/strong>Wednesday, June 11, 10 – 11:45 a.m. PT
Poster Session:<\/strong> P-50\u00a0 \u00a0 \u00a0 \u00a0\u00a0
Poster Number: <\/strong>369<\/p>\n

\n About AXS-12<\/strong>\n <\/p>\n

AXS-12 (reboxetine) is a highly selective and potent norepinephrine reuptake inhibitor and cortical dopamine modulator under development for the treatment of narcolepsy. AXS-12 is thought to modulate noradrenergic activity to promote maintain tone during wakefulness, and noradrenergic and cortical dopamine signaling to promote wakefulness and enhance cognition. AXS-12 has been granted U.S. Food and Drug Administration (FDA) Orphan Drug Designation for the treatment of narcolepsy. AXS-12 is covered by issued patents providing protection to at least 2039. AXS-12 is an investigational drug product not approved by the FDA.<\/p>\n

\n About Solriamfetol<\/strong>\n <\/p>\n

Solriamfetol is a dopamine and norepinephrine reuptake inhibitor (DNRI), TAAR1 agonist, and 5-HT1A<\/sub> agonist being developed for the treatment of attention deficit hyperactivity disorder (ADHD), major depressive disorder (MDD), binge eating disorder (BED), and excessive sleepiness associated with shift work disorder (SWD).<\/p>\n

\n About Axsome Therapeutics<\/strong>\n <\/p>\n

Axsome Therapeutics\u00a0is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in\u00a0the United States. Together, we are on a mission to solve some of the brain\u2019s biggest problems so patients and their loved ones can flourish. For more information, please visit us at\u00a0www.axsome.com<\/strong><\/a>\u00a0and follow us on\u00a0LinkedIn<\/strong><\/a>\u00a0and\u00a0X<\/strong><\/a>.<\/p>\n

\n Forward Looking Statements<\/strong>\n <\/p>\n

Certain matters discussed in this press release are \u201cforward-looking statements\u201d. The Company may, in some cases, use terms such as \u201cpredicts,\u201d \u201cbelieves,\u201d \u201cpotential,\u201d \u201ccontinue,\u201d \u201cestimates,\u201d \u201canticipates,\u201d \u201cexpects,\u201d \u201cplans,\u201d \u201cintends,\u201d \u201cmay,\u201d \u201ccould,\u201d \u201cmight,\u201d \u201cwill,\u201d \u201cshould\u201d or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. In particular, the Company\u2019s statements regarding trends and potential future results are examples of such forward-looking statements. The forward-looking statements include risks and uncertainties, including, but not limited to, the commercial success of the Company\u2019s SUNOSI\u00ae<\/sup>, AUVELITY\u00ae<\/sup>, and SYMBRAVO\u00ae<\/sup> products and the success of the Company\u2019s efforts to obtain any additional indication(s) with respect to solriamfetol and\/or AXS-05; the Company\u2019s ability to maintain and expand payer coverage; the success, timing and cost of the Company\u2019s ongoing clinical trials and anticipated clinical trials for the Company\u2019s current product candidates, including statements regarding the timing of initiation, pace of enrollment and completion of the trials (including the Company\u2019s ability to fully fund the Company\u2019s disclosed clinical trials, which assumes no material changes to the Company\u2019s currently projected revenues or expenses), futility analyses and receipt of interim results, which are not necessarily indicative of the final results of the Company\u2019s ongoing clinical trials, and\/or data readouts, and the number or type of studies or nature of results necessary to support the filing of a new drug application (\u201cNDA\u201d) for any of the Company\u2019s current product candidates; the Company\u2019s ability to fund additional clinical trials to continue the advancement of the Company\u2019s product candidates; the timing of and the Company\u2019s ability to obtain and maintain U.S. Food and Drug Administration (\u201cFDA\u201d) or other regulatory authority approval of, or other action with respect to, the Company\u2019s product candidates, including statements regarding the timing of any NDA submission; the Company\u2019s ability to successfully defend its intellectual property or obtain the necessary licenses at a cost acceptable to the Company, if at all; the Company\u2019s ability to successfully resolve any intellectual property litigation, and even if such disputes are settled, whether the applicable federal agencies will approve of such settlements; the successful implementation of the Company\u2019s research and development programs and collaborations; the success of the Company\u2019s license agreements; the acceptance by the market of the Company\u2019s products and product candidates, if approved; the Company\u2019s anticipated capital requirements, including the amount of capital required for the commercialization of SUNOSI, AUVELITY, and SYMBRAVO and for the Company\u2019s commercial launch of its other product candidates, if approved, and the potential impact on the Company\u2019s anticipated cash runway; the Company\u2019s ability to convert sales to recognized revenue and maintain a favorable gross to net sales; unforeseen circumstances or other disruptions to normal business operations arising from or related to domestic political climate, geo-political conflicts or a global pandemic and other factors, including general economic conditions and regulatory developments, not within the Company\u2019s control. The factors discussed herein could cause actual results and developments to be materially different from those expressed in or implied by such statements. The forward-looking statements are made only as of the date of this press release and the Company undertakes no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances.<\/p>\n

\n Investors:<\/strong>
\n
Mark Jacobson
Chief Operating Officer
(212) 332-3243
mjacobson@axsome.com<\/a><\/p>\n

\n Media:<\/strong>
\n
Darren Opland
Director, Corporate Communications
(929) 837-1065
dopland@axsome.com<\/a><\/p>\n

\"\"
\n
\n \"\"\n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

NEW YORK, June 11, 2025 (GLOBE NEWSWIRE) — Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today announced seven presentations, including two featured oral plenary sessions, on AXS-12 and solriamfetol, at SLEEP 2025, the 39th annual meeting of the\u00a0Associated Professional Sleep Societies (APSS), being held\u00a0June 8-11, 2025, in\u00a0Seattle, Washington. Details for the presentations are as follows: AXS-12 Title: ENCORE: Topline Results of a Phase 3 Open-Label Extension and Randomized-Withdrawal Trial of AXS-12 in NarcolepsyLead Author: Richard Bogan, MD, FCCP, FAASM, Associate Clinical Professor at the University of South Carolina School of Medicine in Columbia, SC Poster Presentation Date and Time: Wednesday, June 11, 10 – 11:45 a.m. … <\/p>\n

Continue reading “Axsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-859382","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nAxsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025 - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Axsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025 - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"NEW YORK, June 11, 2025 (GLOBE NEWSWIRE) — Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today announced seven presentations, including two featured oral plenary sessions, on AXS-12 and solriamfetol, at SLEEP 2025, the 39th annual meeting of the\u00a0Associated Professional Sleep Societies (APSS), being held\u00a0June 8-11, 2025, in\u00a0Seattle, Washington. 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(NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today announced seven presentations, including two featured oral plenary sessions, on AXS-12 and solriamfetol, at SLEEP 2025, the 39th annual meeting of the\u00a0Associated Professional Sleep Societies (APSS), being held\u00a0June 8-11, 2025, in\u00a0Seattle, Washington. Details for the presentations are as follows: AXS-12 Title: ENCORE: Topline Results of a Phase 3 Open-Label Extension and Randomized-Withdrawal Trial of AXS-12 in NarcolepsyLead Author: Richard Bogan, MD, FCCP, FAASM, Associate Clinical Professor at the University of South Carolina School of Medicine in Columbia, SC Poster Presentation Date and Time: Wednesday, June 11, 10 – 11:45 a.m. … Continue reading \"Axsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/","og_site_name":"Market Newsdesk","article_published_time":"2025-06-11T11:03:33+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQ2NjQ5MSM2OTg0ODQ2IzIwMTg1NTg=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Axsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025","datePublished":"2025-06-11T11:03:33+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/"},"wordCount":1238,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQ2NjQ5MSM2OTg0ODQ2IzIwMTg1NTg=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/axsome-therapeutics-showcases-innovation-in-sleep-medicine-with-multiple-presentations-for-axs-12-and-solriamfetol-at-sleep-2025\/","name":"Axsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025 - 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