{"id":858410,"date":"2025-06-09T07:48:05","date_gmt":"2025-06-09T11:48:05","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\/"},"modified":"2025-06-09T07:48:05","modified_gmt":"2025-06-09T11:48:05","slug":"biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\/","title":{"rendered":"BioRestorative to Present Major Update on Promising Preliminary Phase 2 BRTX-100 Data at ISSCR 2025"},"content":{"rendered":"
\n

\n \u2013 New blinded safety and efficacy data from 30 patients in ongoing Phase 2 trial to be unveiled June 13, 2025 \u2013<\/em>\n <\/p>\n

\n \u2013 ISSCR 2025 is the premier global event for stem cell research, drawing nearly 4,000 leaders from academia, biotech, and pharma \u2013<\/em>\n <\/p>\n

\n \u2013 BioRestorative to release new clinical data to the public prior to market open on June 13th \u2013<\/em>\n <\/p>\n

MELVILLE, N.Y., June 09, 2025 (GLOBE NEWSWIRE) — BioRestorative Therapies, Inc.<\/em> (\u201cBioRestorative,\u201d \u201cBRTX\u201d or the \u201cCompany\u201d) (NASDAQ: BRTX), a clinical-stage regenerative medicine company developing stem cell-based therapies for serious musculoskeletal conditions, today announced that new preliminary, blinded clinical data from 30 patients enrolled in its ongoing Phase 2 trial of BRTX-100 for the treatment of chronic lumbar disc disease (cLDD) will be presented at the prestigious International Society for Stem Cell Research (ISSCR) 2025 Annual Meeting, held June 11\u201314, 2025, in Hong Kong.<\/p>\n

The highly anticipated presentation will be delivered by Francisco Silva, Vice President of Research and Development at BioRestorative, on Friday, June 13, at 5:00 p.m. HKT, as part of ISSCR 2025\u2019s clinical innovations track. The Company will issue a press release pre-market that day, detailing the newly reported data.<\/p>\n

\u201cThis represents a milestone moment for BioRestorative,\u201d said Lance Alstodt, Chief Executive Officer. \u201cWith preliminary data from twice as many patients as previously shared, we are seeing strong, consistent signals around both safety and functional improvement. We are eager to bring this update to the global scientific community at the world\u2019s most influential stem cell conference.\u201d<\/p>\n

BRTX-100 is BioRestorative\u2019s lead clinical candidate \u2014 a hypoxic-cultured, autologous mesenchymal stem cell therapy designed to target areas of the body with limited blood flow, such as damaged spinal discs. The ongoing Phase 2 study is a prospective, randomized, double-blinded, placebo-controlled trial evaluating BRTX-100 in patients with cLDD across up to 16 U.S. clinical sites. A total of 99 patients will be enrolled, randomized 2:1 to receive either BRTX-100 or placebo via a single intradiscal injection.<\/p>\n

The presentation, titled \u201cStem Cell Therapy for Chronic Lumbar Disc Disease: Phase 2 Clinical Safety and Feasibility Data of Intradiscal Injections of Hypoxic Cultured Mesenchymal Stem Cells,\u201d will highlight key preliminary outcomes focused on patient-reported pain and function metrics, as well as safety endpoints.<\/p>\n

\n About the ISSCR 2025 Annual Meeting<\/strong>\n <\/p>\n

ISSCR 2025 is the largest and most influential gathering of stem cell scientists and regenerative medicine experts globally, attracting nearly 4,000 participants from over 80 countries. It serves as a key venue for groundbreaking clinical and translational research, offering BioRestorative a high-profile platform to share its latest advancements.<\/p>\n

For more information on ISSCR 2025, visit www.isscr.org<\/u><\/a>.<\/p>\n

\n About BioRestorative Therapies, Inc.<\/strong>\n <\/p>\n

BioRestorative (NASDAQ: BRTX) is a clinical-stage biotechnology company developing cell-based therapies using adult stem cells to address unmet needs in musculoskeletal and metabolic diseases. The Company\u2019s pipeline includes BRTX-100, a novel therapy targeting chronic lumbar disc disease, and ThermoStem\u00ae<\/sup>, a platform focused on brown adipose (fat) biology for the treatment of obesity and metabolic disorders. The Company also operates a commercial BioCosmeceutical platform.<\/p>\n

For more information, please visit www.biorestorative.com<\/u><\/a>.<\/p>\n

\n Forward-Looking Statements<\/strong>\n <\/p>\n

This press release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events or results to differ materially from those projected in the forward-looking statements as a result of various factors and other risks, including, without limitation, those set forth in the Company’s latest Form 10-K, filed with the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements. The forward-looking statements in this release are made as of the date hereof and the Company undertakes no obligation to update such statements.<\/p>\n

\n Contact:<\/strong>
\n
Stephen Kilmer
Investor Relations
Direct: (646) 274-3580
Email: skilmer@biorestorative.com<\/a><\/p>\n

\"\"
\n
\n \"\"\n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

\u2013 New blinded safety and efficacy data from 30 patients in ongoing Phase 2 trial to be unveiled June 13, 2025 \u2013 \u2013 ISSCR 2025 is the premier global event for stem cell research, drawing nearly 4,000 leaders from academia, biotech, and pharma \u2013 \u2013 BioRestorative to release new clinical data to the public prior to market open on June 13th \u2013 MELVILLE, N.Y., June 09, 2025 (GLOBE NEWSWIRE) — BioRestorative Therapies, Inc. (\u201cBioRestorative,\u201d \u201cBRTX\u201d or the \u201cCompany\u201d) (NASDAQ: BRTX), a clinical-stage regenerative medicine company developing stem cell-based therapies for serious musculoskeletal conditions, today announced that new preliminary, blinded clinical data from 30 patients enrolled in its ongoing Phase 2 trial of BRTX-100 for the treatment of chronic lumbar disc … <\/p>\n

Continue reading “BioRestorative to Present Major Update on Promising Preliminary Phase 2 BRTX-100 Data at ISSCR 2025”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-858410","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nBioRestorative to Present Major Update on Promising Preliminary Phase 2 BRTX-100 Data at ISSCR 2025 - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BioRestorative to Present Major Update on Promising Preliminary Phase 2 BRTX-100 Data at ISSCR 2025 - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"\u2013 New blinded safety and efficacy data from 30 patients in ongoing Phase 2 trial to be unveiled June 13, 2025 \u2013 \u2013 ISSCR 2025 is the premier global event for stem cell research, drawing nearly 4,000 leaders from academia, biotech, and pharma \u2013 \u2013 BioRestorative to release new clinical data to the public prior to market open on June 13th \u2013 MELVILLE, N.Y., June 09, 2025 (GLOBE NEWSWIRE) — BioRestorative Therapies, Inc. (\u201cBioRestorative,\u201d \u201cBRTX\u201d or the \u201cCompany\u201d) (NASDAQ: BRTX), a clinical-stage regenerative medicine company developing stem cell-based therapies for serious musculoskeletal conditions, today announced that new preliminary, blinded clinical data from 30 patients enrolled in its ongoing Phase 2 trial of BRTX-100 for the treatment of chronic lumbar disc … Continue reading "BioRestorative to Present Major Update on Promising Preliminary Phase 2 BRTX-100 Data at ISSCR 2025"\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-06-09T11:48:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQ2NTI5NCM2OTgxNDU4IzUwMDA4MDA0MA==\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"BioRestorative to Present Major Update on Promising Preliminary Phase 2 BRTX-100 Data at ISSCR 2025\",\"datePublished\":\"2025-06-09T11:48:05+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\\\/\"},\"wordCount\":661,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTQ2NTI5NCM2OTgxNDU4IzUwMDA4MDA0MA==\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biorestorative-to-present-major-update-on-promising-preliminary-phase-2-brtx-100-data-at-isscr-2025\\\/\",\"name\":\"BioRestorative to Present Major Update on Promising Preliminary Phase 2 BRTX-100 Data at ISSCR 2025 - 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