{"id":850799,"date":"2025-05-14T07:06:13","date_gmt":"2025-05-14T11:06:13","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-awards-multiple-g-rex-grants-to-leading-investigators-at-the-university-of-southern-california-usc-and-the-childrens-hospital-of-los-angeles-chla\/"},"modified":"2025-05-14T07:06:13","modified_gmt":"2025-05-14T11:06:13","slug":"scaleready-awards-multiple-g-rex-grants-to-leading-investigators-at-the-university-of-southern-california-usc-and-the-childrens-hospital-of-los-angeles-chla","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-awards-multiple-g-rex-grants-to-leading-investigators-at-the-university-of-southern-california-usc-and-the-childrens-hospital-of-los-angeles-chla\/","title":{"rendered":"ScaleReady awards multiple G-Rex\u00ae Grants to leading investigators at the University of Southern California (USC) and the Children’s Hospital of Los Angeles (CHLA)"},"content":{"rendered":"
\n

PR Newswire<\/p>\n<\/p><\/div>\n

\n

\n
\n ST. PAUL, Minn.<\/span>
\n <\/span>, May 14, 2025<\/span><\/span> \/PRNewswire\/ — ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation (NASDAQ: TECH) and CellReady announced today three G-Rex Grants that have been awarded to faculty members at the University of Southern California<\/span> (USC<\/span>) and the Children’s Hospital of Los Angeles<\/span> (CHLA). The funding totaling $1,025,000<\/span> will support the translation of various cell and gene therapy initiatives into the clinic.<\/p>\n

Dr. Mohamed Abou<\/span>-el-Enein, Executive Director of the USC<\/span>\/CHLA Cell Therapy Program and Founding Director of the cGMP Facility, received a $300,000<\/span> G-Rex Grant to further support the development of a novel non-viral manufacturing platform for CAR-T cell therapies. Initially funded by the INFR5 Grant from the California Institute of Regenerative Medicine (CIRM), this additional support will help accelerate and enhance the platform’s progress.<\/p>\n

“After extensive evaluation, we’ve identified the G-Rex system as the platform of choice for establishing an efficient, scalable, and cost-effective CAR-T manufacturing process that supports both my lab and our clients within the GMP facility. The system enables high-yield cell expansion, robust scale-up, and impressive consistency within a compact footprint. By integrating this platform, we are advancing our mission as a center of excellence in CAR-T manufacturing and delivering practical solutions for teams bringing cell therapies to patients,” said Mohamed Abou<\/span>-el-Enein M.D., Ph.D.<\/p>\n

Dr. Saul Priceman<\/span>, Founding Director of the Keck School of Medicine of USC<\/span>\/ USC<\/span> Norris Comprehensive Cancer Center for Cancer Cellular Immunotherapy Research (CCCIR), received a $275,000<\/span> G-Rex Grant for the development of a G-Rex based CAR-T cell process to advance a novel clinically-active CAR-T cell therapy into a Phase 1\/2 clinical trial for the treatment of metastatic solid cancers. The laboratory is also investigating viral and non-viral engineering strategies that will be adapted using the G-Rex platform, which will address current cell manufacturing bottlenecks and help expand preclinical and clinical research efforts. “While our clinical experiences to date have used more conventional cell manufacturing platforms, we are excited about translating our new cellular immunotherapies using the G-Rex production system across the USC<\/span> and CHLA campuses,” said Saul Priceman<\/span>, Ph.D.\u00a0<\/p>\n

Dr. Shahab Asgharzadeh<\/span>, Director of the Neuroblastoma Basic and Translational Program at CHLA, received a $250,000<\/span> G-Rex Grant to support late-stage preclinical development of a novel Chimeric TGFB Signaling Receptor (CTSR) Enabled Anti-B7H3 CAR-T cell therapy in children and Adolescent and Young Adults (AYA) with Recurrent Solid Tumors.\u00a0 This program is supported by an existing CIRM CLIN1 Grant.<\/p>\n

Dr. Preet Chaudhary<\/span>, Professor of Medicine and Chief of the Nohl Division of Hematology and\u00a0Center for Blood Diseases in the Department of Medicine, received a $200,000<\/span> G-Rex Grant \u00a0for the process development and IND submission of a novel Synthetic Immune Receptor (SIR) engineered T cell therapy for the treatment of solid tumors. \u00a0This program is supported by a CIRM TRAN1 Grant.<\/p>\n

“USC<\/span> and CHLA have assembled a world-class team of innovators in the cell therapy field with the intent of making significant contributions to the cell and gene-modified cell therapy (CGT) field. We are impressed by the thoroughness of their CGT manufacturing selection process and having G-Rex selected as the platform to support their current and future clinical plans is an honor,” said John Wilson<\/span>, CEO of Wilson Wolf<\/span> and co-inventor of G-Rex.<\/p>\n

ScaleReady’s G-Rex Grant Program is advancing the state of CGT development and manufacturing by awarding individual Grant Awards worth up to $300,000<\/span>.\u00a0 With nearly 200 grant awards already made and over 50 new applications in queue, the G-Rex Grant Program has been extended with millions of dollars in additional funding. G-Rex Grant Recipients also gain access to exclusive support from ScaleReady’s growing consortium of G-Rex Grant Partners who bring best-in-class tools and technologies as well as unparalleled knowledge and expertise in the areas of cGMP manufacturing, quality and regulatory affairs, CGT business operations, and more.<\/p>\n

\n For more information about the G-Rex\u00ae Grant Program, please contact <\/b>
\n
\n info@scaleready.com<\/a>
\n <\/b>
\n .<\/b>\n <\/p>\n

\n About ScaleReady
<\/b>ScaleReady provides the field of cell and gene-modified cell therapy (CGT) with a G-Rex centric manufacturing platform that enables the world’s most practical, flexible, scalable, and affordable CGT drug product development and manufacturing.<\/p>\n

The G-Rex manufacturing platform is currently used by a rapidly growing list of over 800 organizations and is producing drug products for approximately 50% of CGT clinical trials as well as 5 commercially approved CGT drugs.<\/p>\n

CGT entities relying on the breadth and scope of ScaleReady’s expertise can expect to save years of time and millions of dollars on the path to CGT commercialization.<\/p>\n

For more information about the ScaleReady G-Rex\u00ae Grant Program, please contact info@scaleready.com<\/a>.<\/p>\n

\n About Wilson Wolf Manufacturing
<\/b>
\n Wilson Wolf<\/span> (www.wilsonwolf.com<\/a>) is dedicated to simplifying cell and gene-modified cell (CGT) therapy research, process development, and manufacturing.\u00a0 This is being accomplished through its scalable G-Rex technology, which is used throughout the world in CGT applications ranging from basic research to commercial drug production.<\/p>\n

\n Wilson Wolf’s<\/span> mission is to create hope for cancer patients, one G-Rex\u00ae device at a time.<\/p>\n

\n About Bio-Techne Corporation
<\/b>Bio-Techne Corporation (NASDAQ: TECH) is a global life sciences company providing innovative tools and bioactive reagents for the research and clinical diagnostic communities. Bio-Techne, in partnership with Wilson Wolf<\/span>, is creating products such as media and cytokines that are specifically tailored to G-Rex\u00ae Bioreactors, including right-sized reagent quantities in containers that are tailored to high throughput closed-system manufacturing. For more information on Bio-Techne and its brands, please visit https:\/\/www.bio-techne.com<\/a> or follow the Company on social media at: Facebook, LinkedIn, Twitter or YouTube.<\/p>\n

Contact: David Clair<\/span>, Vice President, Investor Relations & Corporate Development
david.clair@bio-techne.com<\/a>
612-656-4416\u00a0<\/p>\n

\n About CellReady LLC
<\/b>CellReady is the world’s first and only G-Rex centric contract development and manufacturing organization (CDMO) specializing in G-Rex based cell and gene-modified cell therapy development and manufacturing. The company offers a wide range of services to support the development and commercialization of these therapies.<\/p>\n

CellReady’s mission is to create hope for cancer patients, one G-Rex\u00ae process at a time.<\/p>\n

\n

\n
\n \"ScaleReady
\n <\/a>\n <\/p>\n<\/p><\/div>\n

<\/div>\n

\n \"Cision\" View original content to download multimedia:https:\/\/www.prnewswire.com\/news-releases\/scaleready-awards-multiple-g-rex-grants-to-leading-investigators-at-the-university-of-southern-california-usc-and-the-childrens-hospital-of-los-angeles-chla-302437128.html<\/a><\/p>\n

SOURCE Bio-Techne Corporation<\/p>\n<\/p><\/div>\n

\"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

PR Newswire ST. PAUL, Minn. , May 14, 2025 \/PRNewswire\/ — ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation (NASDAQ: TECH) and CellReady announced today three G-Rex Grants that have been awarded to faculty members at the University of Southern California (USC) and the Children’s Hospital of Los Angeles (CHLA). The funding totaling $1,025,000 will support the translation of various cell and gene therapy initiatives into the clinic. Dr. Mohamed Abou-el-Enein, Executive Director of the USC\/CHLA Cell Therapy Program and Founding Director of the cGMP Facility, received a $300,000 G-Rex Grant to further support the development of a novel non-viral manufacturing platform for CAR-T cell therapies. Initially funded by the INFR5 Grant from the California Institute of Regenerative Medicine … <\/p>\n

Continue reading “ScaleReady awards multiple G-Rex\u00ae Grants to leading investigators at the University of Southern California (USC) and the Children’s Hospital of Los Angeles (CHLA)”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-850799","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nScaleReady awards multiple G-Rex\u00ae Grants to leading investigators at the University of Southern California (USC) and the Children's Hospital of Los Angeles (CHLA) - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-awards-multiple-g-rex-grants-to-leading-investigators-at-the-university-of-southern-california-usc-and-the-childrens-hospital-of-los-angeles-chla\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ScaleReady awards multiple G-Rex\u00ae Grants to leading investigators at the University of Southern California (USC) and the Children's Hospital of Los Angeles (CHLA) - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"PR Newswire ST. PAUL, Minn. , May 14, 2025 \/PRNewswire\/ — ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation (NASDAQ: TECH) and CellReady announced today three G-Rex Grants that have been awarded to faculty members at the University of Southern California (USC) and the Children’s Hospital of Los Angeles (CHLA). The funding totaling $1,025,000 will support the translation of various cell and gene therapy initiatives into the clinic. Dr. Mohamed Abou-el-Enein, Executive Director of the USC\/CHLA Cell Therapy Program and Founding Director of the cGMP Facility, received a $300,000 G-Rex Grant to further support the development of a novel non-viral manufacturing platform for CAR-T cell therapies. 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PAUL, Minn. , May 14, 2025 \/PRNewswire\/ — ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation (NASDAQ: TECH) and CellReady announced today three G-Rex Grants that have been awarded to faculty members at the University of Southern California (USC) and the Children’s Hospital of Los Angeles (CHLA). The funding totaling $1,025,000 will support the translation of various cell and gene therapy initiatives into the clinic. Dr. Mohamed Abou-el-Enein, Executive Director of the USC\/CHLA Cell Therapy Program and Founding Director of the cGMP Facility, received a $300,000 G-Rex Grant to further support the development of a novel non-viral manufacturing platform for CAR-T cell therapies. 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