{"id":847060,"date":"2025-05-06T07:24:23","date_gmt":"2025-05-06T11:24:23","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\/"},"modified":"2025-05-06T07:24:23","modified_gmt":"2025-05-06T11:24:23","slug":"scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\/","title":{"rendered":"ScaleReady awards a $300,000 G-Rex\u00ae Grant to A2 Biotherapeutics, Inc."},"content":{"rendered":"
\n

PR Newswire<\/p>\n<\/p><\/div>\n

\n

\n
\n ST. PAUL, Minn.<\/span>
\n <\/span>, May 6, 2025<\/span><\/span> \/PRNewswire\/ — ScaleReady, in collaboration with Wilson Wolf<\/span>, Bio-Techne Corporation and CellReady, today announced that A2 Biotherapeutics, Inc. (“A2”) has been awarded a $300,000<\/span> G-Rex\u00ae Grant.\u00a0 A2’s G-Rex\u00ae Grant will enable expeditious process development and qualification of a G-Rex-based production system and will enable A2 to evaluate G-Rex for manufacturing cell therapies.<\/p>\n

“We are very impressed by the simplicity and scalability of the G-Rex platform and look forward to exploring its applications in our clinical development programs.” says Dr. Agi Hamburger<\/span>, Chief Operating Officer at A2. “As an early-stage company, the G-Rex Grant provides valuable resources to support the process development and comparability studies.”<\/p>\n

“We appreciate the opportunity to help A2 Biotherapeutics explore an alternative manufacturing pathway that is distinct from the ‘all-in-one’ bioreactor approach.\u00a0 We believe a modular and flexible closed approach is necessary for cell therapy developers to set the basis for LEAN manufacturing while establishing phase appropriate production. This is the best way to generate drug product supply that is commensurate with their total patient demand,” says John Wilson<\/span>, CEO of Wilson Wolf<\/span> and co-inventor of G-Rex.<\/p>\n

As part of the G-Rex Grant, A2 will evaluate the G-CART process, a standardized workflow for assembling CAR-T drug product, currently in development at Cell Ready, the world’s first and only G-Rex centric contract development and manufacturing organization (CDMO). The G-CART process is designed for high-throughput manufacturing in centralized or point of care models and will be readily adaptable to full end-to-end robotic automation for commercial scale production.\u00a0 The G-CART process will make creative use of novel sub-assemblies to streamline the flow of the drug substance through the final assembly line, including the new GMP ProPak cytokines from Bio-Techne.\u00a0 ProPaks are GMP grade, liquid formulated, process-sized cytokines filled in sterile-weldable bags tailormade for use with the G-Rex device.\u00a0 Various interleukins, including IL-2, IL-7, and IL-15 are available in ProPak form.<\/p>\n

A2’s CAR-T cell pipeline is based on their proprietary Tmod\u2122 platform. The Tmod platform is a dual-signal integrator system for cancer cell therapy that consists of an activating receptor and an inhibitory receptor (blocker module). It utilizes tumor loss of heterozygosity to clearly distinguish normal cells containing both the activator and blocker antigens from tumor cells expressing the activator antigen, but which have irreversibly lost the blocker antigen.\u00a0 A2’s current clinical pipeline consists of CAR-T cell therapies targeting various solid tumor indications including colorectal, lung, pancreatic, and ovarian cancers.<\/p>\n

ScaleReady’s G-Rex Grant Program is advancing the state of cell and gene-modified cell therapy (CGT) development and manufacturing by awarding individual Grant Awards worth up to $300,000<\/span>.\u00a0 With nearly 200 grant awards awarded and over 50 new applications in queue, the G-Rex Grant Program has been extended with millions of dollars in additional funding. G-Rex Grant Recipients also gain access to exclusive support from ScaleReady’s growing consortium of G-Rex Grant Partners who bring best-in-class tools and technologies as well as unparalleled knowledge and expertise in the areas of cGMP manufacturing, quality and regulatory affairs, CGT business operations, and more.<\/p>\n

\n For more information about the G-Rex\u00ae Grant Program, please contact <\/b>
\n
\n info@scaleready.com<\/a>
\n <\/b>
\n .<\/b>\n <\/p>\n

\n About ScaleReady
<\/b>ScaleReady provides the field of cell and gene-modified cell therapy (CGT) with a G-Rex centric manufacturing platform that enables the world’s most practical, flexible, scalable, and affordable CGT drug product development and manufacturing.<\/p>\n

The G-Rex manufacturing platform is currently used by a rapidly growing list of over 800 organizations and is producing drug products for approximately 50% of CGT clinical trials as well as 5 commercially approved CGT drugs.<\/p>\n

CGT entities relying on the breadth and scope of ScaleReady’s expertise can expect to save years of time and millions of dollars on the path to CGT commercialization.<\/p>\n

For more information about the ScaleReady G-Rex\u00ae Grant Program, please contact info@scaleready.com<\/a>.<\/p>\n

\n About Wilson Wolf Manufacturing
<\/b>
\n Wilson Wolf<\/span> (www.wilsonwolf.com<\/a>) is dedicated to simplifying cell and gene-modified cell (CGT) therapy research, process development, and manufacturing.\u00a0 This is being accomplished through its scalable G-Rex technology, which is used throughout the world in CGT applications ranging from basic research to commercial drug production.<\/p>\n

\n Wilson Wolf’s<\/span> mission is to create hope for cancer patients, one G-Rex\u00ae device at a time.<\/p>\n

\n About Bio-Techne Corporation
<\/b>Bio-Techne Corporation (NASDAQ: TECH) is a global life sciences company providing innovative tools and bioactive reagents for the research and clinical diagnostic communities. Bio-Techne, in partnership with Wilson Wolf<\/span>, is creating products such as media and cytokines that are specifically tailored to G-Rex\u00ae Bioreactors, including right-sized reagent quantities in containers that are tailored to high throughput closed-system manufacturing. For more information on Bio-Techne and its brands, please visit https:\/\/www.bio-techne.com<\/a> or follow the Company on social media at: Facebook, LinkedIn, Twitter or YouTube.<\/p>\n

Contact: David Clair<\/span>, Vice President, Investor Relations & Corporate Development
david.clair@bio-techne.com<\/a>
612-656-4416<\/p>\n

\n About CellReady LLC
<\/b>CellReady is the world’s first and only G-Rex centric contract development and manufacturing organization (CDMO) specializing in G-Rex based cell and gene-modified cell therapy development and manufacturing. The company offers a wide range of services to support the development and commercialization of these therapies.<\/p>\n

CellReady’s mission is to create hope for cancer patients, one G-Rex\u00ae process at a time.<\/p>\n

\n

\n
\n \"ScaleReady
\n <\/a>\n <\/p>\n<\/p><\/div>\n

\u00a0<\/p>\n

<\/div>\n

\n \"Cision\" View original content to download multimedia:https:\/\/www.prnewswire.com\/news-releases\/scaleready-awards-a-300-000-g-rex-grant-to-a2-biotherapeutics-inc-302435901.html<\/a><\/p>\n

SOURCE Bio-Techne Corporation<\/p>\n<\/p><\/div>\n

\"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

PR Newswire ST. PAUL, Minn. , May 6, 2025 \/PRNewswire\/ — ScaleReady, in collaboration with Wilson Wolf, Bio-Techne Corporation and CellReady, today announced that A2 Biotherapeutics, Inc. (“A2”) has been awarded a $300,000 G-Rex\u00ae Grant.\u00a0 A2’s G-Rex\u00ae Grant will enable expeditious process development and qualification of a G-Rex-based production system and will enable A2 to evaluate G-Rex for manufacturing cell therapies. “We are very impressed by the simplicity and scalability of the G-Rex platform and look forward to exploring its applications in our clinical development programs.” says Dr. Agi Hamburger, Chief Operating Officer at A2. “As an early-stage company, the G-Rex Grant provides valuable resources to support the process development and comparability studies.” “We appreciate the opportunity to help A2 … <\/p>\n

Continue reading “ScaleReady awards a $300,000 G-Rex\u00ae Grant to A2 Biotherapeutics, Inc.”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-847060","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nScaleReady awards a $300,000 G-Rex\u00ae Grant to A2 Biotherapeutics, Inc. - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ScaleReady awards a $300,000 G-Rex\u00ae Grant to A2 Biotherapeutics, Inc. - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"PR Newswire ST. PAUL, Minn. , May 6, 2025 \/PRNewswire\/ — ScaleReady, in collaboration with Wilson Wolf, Bio-Techne Corporation and CellReady, today announced that A2 Biotherapeutics, Inc. (“A2”) has been awarded a $300,000 G-Rex\u00ae Grant.\u00a0 A2’s G-Rex\u00ae Grant will enable expeditious process development and qualification of a G-Rex-based production system and will enable A2 to evaluate G-Rex for manufacturing cell therapies. “We are very impressed by the simplicity and scalability of the G-Rex platform and look forward to exploring its applications in our clinical development programs.” says Dr. Agi Hamburger, Chief Operating Officer at A2. “As an early-stage company, the G-Rex Grant provides valuable resources to support the process development and comparability studies.” “We appreciate the opportunity to help A2 … Continue reading "ScaleReady awards a $300,000 G-Rex\u00ae Grant to A2 Biotherapeutics, Inc."\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-05-06T11:24:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mma.prnewswire.com\/media\/2541888\/ScaleReady_Logo_RGB__2___002.jpg\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"ScaleReady awards a $300,000 G-Rex\u00ae Grant to A2 Biotherapeutics, Inc.\",\"datePublished\":\"2025-05-06T11:24:23+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\\\/\"},\"wordCount\":886,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mma.prnewswire.com\\\/media\\\/2541888\\\/ScaleReady_Logo_RGB__2___002.jpg\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/scaleready-awards-a-300000-g-rex-grant-to-a2-biotherapeutics-inc\\\/\",\"name\":\"ScaleReady awards a $300,000 G-Rex\u00ae Grant to A2 Biotherapeutics, Inc. - 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