{"id":843512,"date":"2025-04-29T10:44:03","date_gmt":"2025-04-29T14:44:03","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/"},"modified":"2025-04-29T10:44:03","modified_gmt":"2025-04-29T14:44:03","slug":"fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/","title":{"rendered":"Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting"},"content":{"rendered":"<h2>\nUpdated clinical and preclinical data showcase iPSC-derived off-the-shelf CAR T-cell therapy products for conditioning chemotherapy-free treatment across autoimmune and cancer indications<br \/>\n<\/h2>\n<div class=\"mw_release\">\n<p align=\"justify\">SAN DIEGO, April  29, 2025  (GLOBE NEWSWIRE) &#8212; Fate Therapeutics, Inc. (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients, today announced that five presentations of clinical and preclinical data from the Company\u2019s induced pluripotent stem cell (iPSC) product platform will be featured at the American Society of Gene and Cell Therapy (ASGCT) 28<sup>th<\/sup> Annual Meeting, being held in\u00a0New Orleans, Louisiana\u00a0on\u00a0May 13-17, 2025.<\/p>\n<p align=\"justify\">The Company has been selected to deliver an oral presentation on the translational data from its Phase 1 clinical trial of FT522, an off-the-shelf, CD19-targeted CAR NK cell product candidate, in patients with relapsed \/ refractory B-cell lymphoma (BCL) (NCT05950334). FT522 is the first product candidate to incorporate Alloimmune Defense Receptor (ADR) technology, which is designed to reduce or eliminate the need for administration of conditioning chemotherapy to patients receiving cell therapies. In addition, the Company will highlight preclinical data from its off-the-shelf, iPSC-derived, CAR T-cell product platform across autoimmune disease, hematological malignancy and solid tumor indications.<\/p>\n<p align=\"justify\">Accepted abstracts are available on the\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=VMX-UW7Frl8QlWzfP8dLQBD5R0ICnXJJHa6JaUPtAOji6UFQpFrA_HE7W0_OfxganglPBvHRq8tJHjtChmhDrsJPCxpXmhI6ozhOVwDQquX8QqlulmoJBh9eK9x-tZmT\" rel=\"nofollow\" target=\"_blank\">ASGCT Annual Meeting\u00a0website<\/a>. Presentation details are as follows:<\/p>\n<p>\n        <strong><br \/>\n          <u>Oral Presentation<\/u><br \/>\n        <\/strong>\n      <\/p>\n<p>\n        <strong>Phase 1 Translational Assessment of an Off-The-Shelf CAR NK Cell Armed with Alloimmune Defense Technology for Conditioning-free Therapy<\/strong>\n      <\/p>\n<p>Session: Innovation in Alternative Cell Therapy Sources<br \/>Location: Room 391-392<br \/>Presentation Date \/ Time: Saturday, May 17, 2025, 11:00 AM CT<\/p>\n<p>\n        <strong><br \/>\n          <u>Poster Presentations<\/u><br \/>\n        <\/strong>\n      <\/p>\n<p>\n        <strong>Alloimmune Defense Receptor Combined with Genetic Ablation of Adhesion Ligand CD58 is a Comprehensive Approach to Promote Functional Persistence of Allogeneic Cell Therapies without Conditioning Chemotherapy<\/strong>\n      <\/p>\n<p>Poster Number: 758<br \/>Presentation Date \/ Time: Tuesday, May 13, 2025, 6:00 PM CT<\/p>\n<p>\n        <strong>Targeting UPAR With Multiplexed-Engineered iPSC-Derived CAR T Cells to Reverse Age- and Insult-Related Fibrotic Disease<\/strong>\n      <\/p>\n<p>Poster Number: 789<br \/>Presentation Date \/ Time: Tuesday, May 13, 2025, 6:00 PM CT<\/p>\n<p>\n        <strong>Next-Generation Off-the-Shelf CAR T-Cell Therapies for Conditioning-Free Treatment of a Broad Spectrum of Autoimmune Diseases and Hematologic Malignancies<\/strong>\n      <\/p>\n<p>Poster Number: 1259<br \/>Presentation Date \/ Time: Wednesday, May 14, 2025, 5:30 PM CT<\/p>\n<p>\n        <strong>FT836, a Novel MICA\/B-targeting CAR T-cell Therapy Engineered to Eliminate the Need for Conditioning Chemotherapy with Broad Activity Across Solid Tumor Indications<\/strong>\n      <\/p>\n<p>Poster Number: 1229<br \/>Presentation Date \/ Time: Wednesday, May 14, 2025, 5:30 PM CT<\/p>\n<p>\n        <strong>About Fate Therapeutics\u2019 iPSC Product Platform<\/strong><br \/>\n        <br \/>Human induced pluripotent stem cells (iPSCs) possess the unique dual properties of unlimited self-renewal and differentiation potential into all cell types of the body. The Company\u2019s proprietary iPSC product platform combines multiplexed-engineering of human iPSCs with single-cell selection to create clonal master iPSC lines. Analogous to master cell lines used to mass produce biopharmaceutical drug products such as monoclonal antibodies, the Company utilizes its clonal master iPSC lines as a starting cell source to manufacture engineered cell products which are well-defined and uniform in composition, can be stored in inventory for off-the-shelf availability, can be administered in combination with other therapies, and can potentially reach a broad patient population. As a result, the Company\u2019s platform is uniquely designed to overcome numerous limitations associated with patient- and donor-sourced cell therapies. Fate Therapeutics\u2019 iPSC product platform is supported by an intellectual property portfolio of over 500 issued patents and 500 pending patent applications.<\/p>\n<p>\n        <strong>About Fate Therapeutics, Inc.<\/strong><br \/>\n        <br \/>Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune diseases. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered master iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company\u2019s pipeline includes iPSC-derived natural killer (NK) cell and T-cell product candidates, which are selectively designed, incorporate novel synthetic controls of cell function, and are intended to deliver multiple therapeutic mechanisms to patients. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=zzAvauN4KW-qzwh_vqhRJm0Je1s12jSO6PT8jGanY_FUtKe_KKoXJbPPGKP0UMWs1GmD9QsOrMNt9l2YJv79gVNAQcb_H1N86Rq5o7V9d_KQ0Sa_zrvmle81cqIH1koS\" rel=\"nofollow\" target=\"_blank\">www.fatetherapeutics.com<\/a>.<\/p>\n<p>\n        <strong>Forward-Looking Statements<\/strong><br \/>\n        <br \/>This release contains &#8220;forward-looking statements&#8221; within the meaning of the Private Securities Litigation Reform Act of 1995 including statements regarding the advancement of and plans related to the Company&#8217;s product candidates, clinical studies and preclinical research and development programs, the Company\u2019s progress, plans and timelines for the clinical investigation of its product candidates, including the initiation and continuation of enrollment in the Company\u2019s clinical trials, the timing and availability of data from the Company\u2019s clinical trials, the therapeutic and market potential of the Company\u2019s research and development programs and product candidates, and the potential capabilities and benefits of the Company\u2019s iPSC product platform. These and any other forward-looking statements in this release are based on management&#8217;s current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include, but are not limited to, the risk that the Company\u2019s research and development programs and product candidates, including those product candidates in clinical investigation, may not demonstrate the requisite safety, efficacy, or other attributes to warrant further development or to achieve regulatory approval, the risk that results observed in prior studies of the Company\u2019s product candidates, including preclinical studies and clinical trials, will not be observed in ongoing or future studies involving these product candidates, the risk of a delay or difficulties in the manufacturing of the Company\u2019s product candidates or in the initiation and conduct of, or enrollment of patients in, any clinical trials, the risk that the Company may cease or delay preclinical or clinical development of any of its product candidates for a variety of reasons (including requirements that may be imposed by regulatory authorities on the initiation or conduct of clinical trials, changes in the therapeutic, regulatory, or competitive landscape for which the Company\u2019s product candidates are being developed, the amount and type of data to be generated or otherwise to support regulatory approval, difficulties or delays in patient enrollment and continuation in the Company\u2019s ongoing and planned clinical trials, difficulties in manufacturing or supplying the Company\u2019s product candidates for clinical testing, failure to demonstrate that a product candidate has the requisite safety, efficacy, or other attributes to warrant further development, and any adverse events or other negative results that may be observed during preclinical or clinical development), and the risk that its product candidates may not produce therapeutic benefits or may cause other unanticipated adverse effects. For a discussion of other risks and uncertainties, and other important factors, any of which could cause the Company\u2019s actual results to differ from those contained in the forward-looking statements, see the risks and uncertainties detailed in the Company\u2019s periodic filings with the Securities and Exchange Commission, including but not limited to the Company\u2019s most recently filed periodic report, and from time to time in the Company\u2019s press releases and other investor communications. Fate Therapeutics is providing the information in this release as of this date and does not undertake any obligation to update any forward-looking statements contained in this release as a result of new information, future events or otherwise.<\/p>\n<p>\n        <strong>Contact:<\/strong><br \/>\n        <br \/>Christina Tartaglia<br \/>Precision AQ<br \/>212.362.1200<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=MIvPjbZtTO-z50Y_IpbkWYyOlrXzFpsUlmlK8xInP55tduBl9VBFTeSiO3LYewTNGWCx_v2NHMeAnzMtuVLyS4fLkqA8EE_nnYRCOThjh2cZvqej9IuHknyAKE5DK9Uc0Rf046PF3UWamA2MBMBlmg==\" rel=\"nofollow\" target=\"_blank\">christina.tartaglia@precisionaq.com<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQ0MDk2NiM2OTExMTMxIzIwMDQyMDE=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/NDdkNzNhYzMtZWE5ZS00ZGY0LWE3NDMtYWZlYjdiNmU0ZGY0LTEwMTU3NzQtMjAyNS0wNC0yOS1lbg==\/tiny\/Fate-Therapeutics-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Updated clinical and preclinical data showcase iPSC-derived off-the-shelf CAR T-cell therapy products for conditioning chemotherapy-free treatment across autoimmune and cancer indications SAN DIEGO, April 29, 2025 (GLOBE NEWSWIRE) &#8212; Fate Therapeutics, Inc. (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients, today announced that five presentations of clinical and preclinical data from the Company\u2019s induced pluripotent stem cell (iPSC) product platform will be featured at the American Society of Gene and Cell Therapy (ASGCT) 28th Annual Meeting, being held in\u00a0New Orleans, Louisiana\u00a0on\u00a0May 13-17, 2025. The Company has been selected to deliver an oral presentation on the translational data from its Phase 1 clinical trial of FT522, an &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-843512","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Updated clinical and preclinical data showcase iPSC-derived off-the-shelf CAR T-cell therapy products for conditioning chemotherapy-free treatment across autoimmune and cancer indications SAN DIEGO, April 29, 2025 (GLOBE NEWSWIRE) &#8212; Fate Therapeutics, Inc. (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients, today announced that five presentations of clinical and preclinical data from the Company\u2019s induced pluripotent stem cell (iPSC) product platform will be featured at the American Society of Gene and Cell Therapy (ASGCT) 28th Annual Meeting, being held in\u00a0New Orleans, Louisiana\u00a0on\u00a0May 13-17, 2025. The Company has been selected to deliver an oral presentation on the translational data from its Phase 1 clinical trial of FT522, an &hellip; Continue reading &quot;Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-04-29T14:44:03+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQ0MDk2NiM2OTExMTMxIzIwMDQyMDE=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting\",\"datePublished\":\"2025-04-29T14:44:03+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\\\/\"},\"wordCount\":1205,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTQ0MDk2NiM2OTExMTMxIzIwMDQyMDE=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\\\/\",\"name\":\"Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting - 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(NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients, today announced that five presentations of clinical and preclinical data from the Company\u2019s induced pluripotent stem cell (iPSC) product platform will be featured at the American Society of Gene and Cell Therapy (ASGCT) 28th Annual Meeting, being held in\u00a0New Orleans, Louisiana\u00a0on\u00a0May 13-17, 2025. The Company has been selected to deliver an oral presentation on the translational data from its Phase 1 clinical trial of FT522, an &hellip; Continue reading \"Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/","og_site_name":"Market Newsdesk","article_published_time":"2025-04-29T14:44:03+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQ0MDk2NiM2OTExMTMxIzIwMDQyMDE=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting","datePublished":"2025-04-29T14:44:03+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/"},"wordCount":1205,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQ0MDk2NiM2OTExMTMxIzIwMDQyMDE=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/fate-therapeutics-announces-five-presentations-on-off-the-shelf-car-t-cell-product-platform-at-asgct-annual-meeting\/","name":"Fate Therapeutics Announces Five Presentations on Off-the-Shelf CAR T-cell Product Platform at ASGCT Annual Meeting - 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