{"id":842247,"date":"2025-04-25T13:03:00","date_gmt":"2025-04-25T17:03:00","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/repare-therapeutics-announces-six-abstracts-accepted-for-presentation-at-aacr-annual-meeting-2025\/"},"modified":"2025-04-25T13:03:00","modified_gmt":"2025-04-25T17:03:00","slug":"repare-therapeutics-announces-six-abstracts-accepted-for-presentation-at-aacr-annual-meeting-2025","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/repare-therapeutics-announces-six-abstracts-accepted-for-presentation-at-aacr-annual-meeting-2025\/","title":{"rendered":"Repare Therapeutics Announces Six Abstracts Accepted for Presentation at AACR Annual Meeting 2025"},"content":{"rendered":"

<\/p>\n

Repare Therapeutics Announces Six Abstracts Accepted for Presentation at AACR Annual Meeting 2025<\/b><\/p>\n

CAMBRIDGE, Mass. & MONTREAL–(BUSINESS WIRE<\/a>)–
\nRepare Therapeutics Inc. (\u201cRepare\u201d or the \u201cCompany\u201d) (Nasdaq: RPTX), a leading clinical-stage precision oncology company, today announced the acceptance of two abstracts for mini-oral presentation and the acceptance of four abstracts for poster presentation at the American Association for Cancer Research (AACR) Annual Meeting, taking place April 25-30, 2025, in Chicago, Illinois.\n<\/p>\n

Mini-Oral Presentation Details:
\n
<\/b>Title:<\/b> Efficacy and safety of the combination PKMYT1-inhibitor lunresertib and ATR-inhibitor camonsertib in patients with ovarian and endometrial cancers: Phase I MYTHIC study (NCT04855656)
\n
Presenter: <\/b>Alison M. Schram, MD, Memorial Sloan Kettering Cancer Center
\n
Session: <\/b>Innovative Approaches to Key Molecular Targets
\n
Session Date and Time: <\/b>Tuesday,April 29 from 2:30-4:30 p.m. CT
\n
Location:<\/b> Room S406 (Vista Ballroom)
\n
Abstract Number:<\/b> CT262\n<\/p>\n

Title:<\/b> The PLK4 inhibitor RP-1664 drives centriole modulation and single agent tumor regressions in preclinical neuroblastoma models
\n
Presenter: <\/b>John M. Maris, MD, Children\u2019s Hospital of Philadelphia
\n
Session: <\/b>Advancing the Science of Childhood Cancers: From Bench to Bedside
\n
Session Date and Time: <\/b>Sunday,April 27 from 3:00-5:00 p.m. CT
\n
Location: <\/b>Room E353 C
\n
Abstract Number:<\/b> 1201\n<\/p>\n

Poster Presentation Details:<\/b><\/p>\n

Title:<\/b> A dual mechanism of sensitivity to PLK4 inhibition by RP-1664 in neuroblastoma
\n
Presenter: <\/b>Michal Zimmermann, PhD, Repare Therapeutics
\n
Session: <\/b>Cell Cycle Effects of Anticancer Drugs
\n
Session Date and Time: <\/b>Sunday,April 27 from 2:00-5:00 p.m. CT
\n
Location:<\/b> Poster Section 17
\n
Poster Number:<\/b> 9
\n
Abstract Number:<\/b> 365\n<\/p>\n

Title:<\/b> RP-1664: A potent and selective PLK4 inhibitor causing tumor regressions in TRIM37-high xenograft models of solid tumors
\n
Presenter: <\/b>Anne Roulston, PhD, Repare Therapeutics
\n
Session: <\/b>Kinase and Phosphatase Inhibitors 1
\n
Session Date and Time: <\/b>Monday,April 28 from 9:00 a.m-12:00 p.m. CT
\n
Location:<\/b> Poster Section 21
\n
Poster Number:<\/b> 9
\n
Abstract Number:<\/b> 1734\n<\/p>\n

Title:<\/b> Pan-cancer analysis of TRIM37<\/i> copy-number and development of fit-for-screening in situ hybridization tools
\n
Presenter: <\/b>Isabel Soria-Bretones, PhD, Repare Therapeutics
\n
Session: <\/b>Diagnostic Biomarkers 2
\n
Session Date and Time: <\/b>Sunday,April 27 from 2:00-5:00 p.m. CT
\n
Location:<\/b> Poster Section 31
\n
Poster Number:<\/b> 2
\n
Abstract Number:<\/b> 717\n<\/p>\n

Title:<\/b> Targeting CCNE1<\/i> amplification in gastric cancer
\n
Presenter: <\/b>Sung Joo Jang, Columbia University Irving Medical Center
\n
Session: <\/b>Protein Kinases and Phosphatases as Targets for Therapy
\n
Session Date and Time: <\/b>Wednesday,April 30 from 9:00 a.m.-12:00 p.m. CT
\n
Location:<\/b> Poster Section 24
\n
Poster Number:<\/b> 4
\n
Abstract Number:<\/b> 6942\n<\/p>\n

\nA copy of each poster presentation is available on the Scientific Resources<\/a> page of the Repare Therapeutics website and a copy of each mini-oral presentation will be available on the Scientific Resources<\/a> page of the Repare Therapeutics website at the start of each mini-oral session.\n<\/p>\n

About Repare Therapeutics Inc.<\/b><\/p>\n

\nRepare Therapeutics is a clinical-stage precision oncology company enabled by its proprietary synthetic lethality approach to the discovery and development of novel therapeutics. The Company utilizes its genome-wide, CRISPR-enabled SNIPRx\u00ae<\/sup> platform to systematically discover and develop highly targeted cancer therapies focused on genomic instability, including DNA damage repair. The Company\u2019s clinical-stage pipeline includes RP-1664, a Phase 1 PLK4 inhibitor; RP-3467, a Phase 1 Pol\u03b8 ATPase inhibitor; and lunresertib, a PKMYT1 inhibitor. For more information, please visit www.reparerx.com<\/a> and follow @Reparerx on X (formerly Twitter) and LinkedIn.\n<\/p>\n

\"\"<\/p>\n

View source version on businesswire.com: <\/span>https:\/\/www.businesswire.com\/news\/home\/20250425074570\/en\/<\/a><\/span><\/p>\n

Investor Relations & Media Contact:
\n<\/b>
Matthew DeYoung
\n
Investor Relations and Media
\n
Argot Partners
\n
investors@reparerx.com<\/a><\/p>\n

KEYWORDS:<\/b> United States North America Canada Massachusetts<\/p>\n

INDUSTRY KEYWORDS:<\/b> Biotechnology Technology Health Pharmaceutical Biometrics Oncology Research Software Genetics Science Clinical Trials<\/p>\n

MEDIA:<\/b><\/p>\n\n","protected":false},"excerpt":{"rendered":"

Repare Therapeutics Announces Six Abstracts Accepted for Presentation at AACR Annual Meeting 2025 CAMBRIDGE, Mass. & MONTREAL–(BUSINESS WIRE)– Repare Therapeutics Inc. (\u201cRepare\u201d or the \u201cCompany\u201d) (Nasdaq: RPTX), a leading clinical-stage precision oncology company, today announced the acceptance of two abstracts for mini-oral presentation and the acceptance of four abstracts for poster presentation at the American Association for Cancer Research (AACR) Annual Meeting, taking place April 25-30, 2025, in Chicago, Illinois. Mini-Oral Presentation Details: Title: Efficacy and safety of the combination PKMYT1-inhibitor lunresertib and ATR-inhibitor camonsertib in patients with ovarian and endometrial cancers: Phase I MYTHIC study (NCT04855656) Presenter: Alison M. Schram, MD, Memorial Sloan Kettering Cancer Center Session: Innovative Approaches to Key Molecular Targets Session Date and Time: Tuesday,April 29 … <\/p>\n

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(\u201cRepare\u201d or the \u201cCompany\u201d) (Nasdaq: RPTX), a leading clinical-stage precision oncology company, today announced the acceptance of two abstracts for mini-oral presentation and the acceptance of four abstracts for poster presentation at the American Association for Cancer Research (AACR) Annual Meeting, taking place April 25-30, 2025, in Chicago, Illinois. Mini-Oral Presentation Details: Title: Efficacy and safety of the combination PKMYT1-inhibitor lunresertib and ATR-inhibitor camonsertib in patients with ovarian and endometrial cancers: Phase I MYTHIC study (NCT04855656) Presenter: Alison M. 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