{"id":841370,"date":"2025-04-24T07:23:45","date_gmt":"2025-04-24T11:23:45","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/"},"modified":"2025-04-24T07:23:45","modified_gmt":"2025-04-24T11:23:45","slug":"pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/","title":{"rendered":"Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting"},"content":{"rendered":"<h2>\nPoster presentation on Monday, June 2, 2025 from 1:30 \u2013 4:30 PM CDT at the ASCO Annual Meeting<br \/>\n<\/h2>\n<div class=\"mw_release\">\n<p align=\"justify\">MIAMI, April  24, 2025  (GLOBE NEWSWIRE) &#8212; <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=8ZGTFF7VVD0OaWDqvIIvBrNyuVdAmIKvyT495kqD8MNPsHsurllPcJpRG6_xShserGsHQiPWXDgYoPw4Xbf-DWb3-1RzZ3RI_YSq-1ZMyCs=\" rel=\"nofollow\" target=\"_blank\"><u>Pasithea Therapeutics Corp.<\/u><\/a> (NASDAQ: KTTA) (\u201cPasithea\u201d or the \u201cCompany\u201d), a clinical-stage biotechnology company developing PAS-004, a next-generation macrocyclic MEK inhibitor, for the treatment of neurofibromatosis type 1 (NF1) and other MAPK pathway driven indications, today announced the acceptance of an abstract for a poster prenstation at the Annual Meeting of the American Society for Clinical Oncology (ASCO) taking place May 30 \u2013 June 3, 2025, in Chicago, Illinois.<\/p>\n<p align=\"justify\">The Company will present updated interim clinical data from its onging Phase 1 clinical trial of PAS-004 in patients with MAPK pathway driven advanced solid tumors.<\/p>\n<p align=\"justify\">\u201cWe are pleased to present interim clinical data of PAS-004 through cohort 4A and 4B, that to date has demonstrated clinical activity, target engagement, and a favorable safety profile,\u201d said Dr. Tiago Reis Marques, Chief Executive Officer of Pasithea. \u201cWe believe PAS-004\u2019s emerging profile may achieve the sweet spot between PK, PD and tolerability and may make PAS-004 an ideal candidate for the treatment of NF1 related cutaneous and plexiform neurofibromas as well as a potential candidate for treatment of various cancers and MAPK pathway driven diseases.\u201d<\/p>\n<p align=\"justify\">\n        <strong>Presentation and poster details<\/strong>\n      <\/p>\n<p>Title: Phase 1 dose-escalation study of the safety and pharmacokinetics of PAS-004, a macrocyclic MEK inhibitor, for the treatment of patients with MAPK pathway\u2013driven advanced solid tumors<br \/>Session: Poster Session \u2013 Developmental Therapeutics \u2013 Molecularly Targeted Agents and Tumor Biology <br \/>Poster Board: 440<br \/>Date and Time: 6\/2\/2025, 1:30 \u2013 4:30 PM CDT<\/p>\n<p align=\"justify\">The full abstract will be available on the <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=L6v9M6LzlncDqVtZUsQ1OLHd8rQpK0jaCfpJnesOZ3xMwC2Kg0kWycFfk1tRAtjtjChhlpJjcbj6Psa_N9V6lAl9HNwJ-8FNgeC9P77ytRVw0lN8vPG2KksEmdM6kEaV9NRIDeFjGYDqBT9ooYu_DA==\" rel=\"nofollow\" target=\"_blank\"><u>ASCO\u00ae\u00a0website<\/u><\/a>\u00a0on May 22, 2025, at 5:00 p.m. ET.<\/p>\n<p align=\"justify\">The ongoing Phase 1 clinical trial is a multi-center, open-label, dose escalation 3+3 study design to evaluate the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and preliminary efficacy of PAS-004 in patients with MAPK pathway driven advanced solid tumors with a documented RAS, NF1 or RAF mutation or patients who have failed BRAF\/MEK inhibition (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=BGS0wSUjJBuZMznXW0Q5Vj03vdH5LJmM6-GOCeNdTF_LWVnzG6H0FlYPJ_tLRSB1AiF3ObRIR1YOa5mr3tNNsefFvxJa5rG4tG_EihNOXIpkCK86HUe-C4GAEF2DMQr5\" rel=\"nofollow\" target=\"_blank\">NCT06299839<\/a>).<\/p>\n<p align=\"justify\">\n        <strong>About Pasithea Therapeutics Corp.<\/strong>\n      <\/p>\n<p align=\"justify\">Pasithea is a clinical-stage biotechnology company focused on the discovery, research and development of innovative treatments for central nervous system (CNS) disorders, RASopathies and MAPK pathway driven diseases.<\/p>\n<p align=\"justify\">\n        <strong>Forward-Looking Statements<\/strong>\n      <\/p>\n<p align=\"justify\">This press release contains statements that constitute \u201cforward-looking statements\u201d made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include statements regarding the Company\u2019s ongoing Phase 1 clinical trial of PAS-004 in advanced cancer patients, the Company\u2019s planned Phase 1\/1b clinical trial of PAS-004 in adult NF1 patients, and the safety, tolerability, pharmacokinetic (PK), pharmacodynamics (PD) and preliminary efficacy of PAS-004, as well as all other statements, other than statements of historical fact, regarding the Company\u2019s current views and assumptions with respect to future events regarding its business, as well as other statements with respect to the Company\u2019s plans, assumptions, expectations, beliefs and objectives, the success of the Company\u2019s current and future business strategies, product development, pre-clinical studies, clinical studies, clinical and regulatory timelines, market opportunity, competitive position, business strategies, potential growth opportunities and other statements that are predictive in nature. Forward-looking statements are subject to numerous conditions, many of which are beyond the control of the Company. While the Company believes these forward-looking statements are reasonable, undue reliance should not be placed on any such forward-looking statements, which are based on information available to the Company on the date of this release. These forward-looking statements are based upon current estimates and assumptions and are subject to various risks and uncertainties, including risks that future clinical trial results may not match results observed to date, may be negative or ambiguous, or may not reach the level of statistical significance required for regulatory approval, as well as other factors set forth in the Company\u2019s most recent Annual Report on Form 10-K, Quarterly Report on Form 10-Q and other filings made with the U.S. Securities and Exchange Commission (SEC). Thus, actual results could be materially different. The Company undertakes no obligation to update these statements whether as a result of new information, future events or otherwise, after the date of this release, except as required by law.<\/p>\n<p align=\"justify\">\n        <strong>Pasithea Therapeutics Contact<\/strong>\n      <\/p>\n<p>Patrick Gaynes<br \/>Corporate Communications<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=5RPpYpncAZhiDn0VilCgPc23EXN3jdFuUtDG1VKZEL9rS5myvnUiQ1aA50Vsd4VdXXs4-vS3ITm4_C4GfMxutGkMP0wPANhH52r2D2-4EGZkVVu8wbvm8axtyK2wEWzaZtNjyo3pB3xoseg9VuDBKDUTxzDcoFO6BrrrKpJ5wa3pQDyrF91h992NJJI2ZOB3z-HhTpVJoNuNkp3D1c9IANLTf8W0f7zrGYRWOa_bXWfkbc0JfN6vhsIT1zERrcQURSCiQvI0zhxFLnbHJjdp6A==\" rel=\"nofollow\" target=\"_blank\">pgaynes@pasithea.com<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQzODA2MiM2OTAyNzcwIzIyMDk2ODM=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/NjMzYTdkYTMtYTViYS00MmE2LWE5M2QtOGRmODA2MTM1NzZlLTEyMjEyMzYtMjAyNS0wNC0yNC1lbg==\/tiny\/Pasithea.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Poster presentation on Monday, June 2, 2025 from 1:30 \u2013 4:30 PM CDT at the ASCO Annual Meeting MIAMI, April 24, 2025 (GLOBE NEWSWIRE) &#8212; Pasithea Therapeutics Corp. (NASDAQ: KTTA) (\u201cPasithea\u201d or the \u201cCompany\u201d), a clinical-stage biotechnology company developing PAS-004, a next-generation macrocyclic MEK inhibitor, for the treatment of neurofibromatosis type 1 (NF1) and other MAPK pathway driven indications, today announced the acceptance of an abstract for a poster prenstation at the Annual Meeting of the American Society for Clinical Oncology (ASCO) taking place May 30 \u2013 June 3, 2025, in Chicago, Illinois. The Company will present updated interim clinical data from its onging Phase 1 clinical trial of PAS-004 in patients with MAPK pathway driven advanced solid tumors. \u201cWe &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-841370","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Poster presentation on Monday, June 2, 2025 from 1:30 \u2013 4:30 PM CDT at the ASCO Annual Meeting MIAMI, April 24, 2025 (GLOBE NEWSWIRE) &#8212; Pasithea Therapeutics Corp. (NASDAQ: KTTA) (\u201cPasithea\u201d or the \u201cCompany\u201d), a clinical-stage biotechnology company developing PAS-004, a next-generation macrocyclic MEK inhibitor, for the treatment of neurofibromatosis type 1 (NF1) and other MAPK pathway driven indications, today announced the acceptance of an abstract for a poster prenstation at the Annual Meeting of the American Society for Clinical Oncology (ASCO) taking place May 30 \u2013 June 3, 2025, in Chicago, Illinois. The Company will present updated interim clinical data from its onging Phase 1 clinical trial of PAS-004 in patients with MAPK pathway driven advanced solid tumors. \u201cWe &hellip; Continue reading &quot;Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-04-24T11:23:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQzODA2MiM2OTAyNzcwIzIyMDk2ODM=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting\",\"datePublished\":\"2025-04-24T11:23:45+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\\\/\"},\"wordCount\":704,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTQzODA2MiM2OTAyNzcwIzIyMDk2ODM=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\\\/\",\"name\":\"Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/","og_locale":"en_US","og_type":"article","og_title":"Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting - Market Newsdesk","og_description":"Poster presentation on Monday, June 2, 2025 from 1:30 \u2013 4:30 PM CDT at the ASCO Annual Meeting MIAMI, April 24, 2025 (GLOBE NEWSWIRE) &#8212; Pasithea Therapeutics Corp. (NASDAQ: KTTA) (\u201cPasithea\u201d or the \u201cCompany\u201d), a clinical-stage biotechnology company developing PAS-004, a next-generation macrocyclic MEK inhibitor, for the treatment of neurofibromatosis type 1 (NF1) and other MAPK pathway driven indications, today announced the acceptance of an abstract for a poster prenstation at the Annual Meeting of the American Society for Clinical Oncology (ASCO) taking place May 30 \u2013 June 3, 2025, in Chicago, Illinois. The Company will present updated interim clinical data from its onging Phase 1 clinical trial of PAS-004 in patients with MAPK pathway driven advanced solid tumors. \u201cWe &hellip; Continue reading \"Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/","og_site_name":"Market Newsdesk","article_published_time":"2025-04-24T11:23:45+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQzODA2MiM2OTAyNzcwIzIyMDk2ODM=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting","datePublished":"2025-04-24T11:23:45+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/"},"wordCount":704,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQzODA2MiM2OTAyNzcwIzIyMDk2ODM=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/pasithea-therapeutics-to-present-updated-data-from-ongoing-phase-1-trial-of-pas-004-in-advanced-cancer-patients-at-the-2025-asco-annual-meeting\/","name":"Pasithea Therapeutics to Present Updated Data from Ongoing Phase 1 Trial of PAS-004 in Advanced Cancer Patients at the 2025 ASCO Annual Meeting - 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