{"id":839994,"date":"2025-04-22T08:57:04","date_gmt":"2025-04-22T12:57:04","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/"},"modified":"2025-04-22T08:57:04","modified_gmt":"2025-04-22T12:57:04","slug":"tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/","title":{"rendered":"Tarsus to Present Several Scientific Abstracts Highlighting the Global Prevalence of Demodex Blepharitis and the Clinical Impact of XDEMVY at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting"},"content":{"rendered":"
\n

IRVINE, Calif., April 22, 2025 (GLOBE NEWSWIRE) — Tarsus Pharmaceuticals, Inc. (NASDAQ: TARS) will present four distinct data sets highlighting the global prevalence and real-world patient burden of Demodex<\/em> blepharitis, as well as the impact of XDEMVY\u00ae<\/sup> (lotilaner ophthalmic solution) 0.25% in addressing objective measures of disease at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting, taking place April 25-28, 2025, in Los Angeles, Calif.<\/p>\n

\u201cFrom new prevalence data in Japan to real-world results in the US, the findings accepted for oral presentation at ASCRS reinforce the global burden of Demodex<\/em> blepharitis and the potential of XDEMVY to deliver significant improvements in patient outcomes across multiple subtypes, including those with concomitant meibomian gland disease,\u201d said Elizabeth Yeu, M.D., Chief Medical Officer of Tarsus. \u201cWe look forward to continuing to generate new evidence to advance the clinical understanding of XDEMVY and its potential impact on this highly prevalent eyelid disease and on the lives of patients.\u201d<\/p>\n

\n Accepted abstracts include:<\/strong>\n <\/p>\n

\n
\n Longitudinal Evaluation of Disease Burden and Treatment Efficacy in Patients with <\/strong>
\n
\n Demodex<\/em>
\n <\/strong>
\n blepharitis: Orion Registry Interim Results<\/strong>
\n <\/a>
\n
\n Date: Sunday, April 27, 2025, 10:42 \u2013 10:47 a.m. PT<\/strong>
\n
\n Location: Los Angeles Convention Center (LACC) \u2013 Level 2, 512<\/strong>
\n
\n Presenter: Kendall E. Donaldson, M.D., M.S., ABO<\/strong>
\n
A real-world, multi-center study characterizing the burden of Demodex<\/em> blepharitis, the current disease management landscape and key changes in patient outcomes after initiation of treatment with XDEMVY.<\/p>\n

\n
\n Assessment of the <\/strong>
\n
\n Demodex<\/em>
\n <\/strong>
\n Blepharitis Specific Symptoms: The Janus Study<\/strong>
\n <\/a>
\n
\n Date: Monday, April 28, 2025, 8:00 \u2013 8:05 a.m. PT<\/strong>
\n
\n Location: LACC \u2013 Level 2, 506<\/strong>
\n
\n Presenter: Nicole R. Fram, M.D., ABO<\/strong>
\n
A prospective, observational study that compared symptoms and clinical outcomes in patients with Demodex<\/em> blepharitis to patients without Demodex<\/em> blepharitis.<\/p>\n

\n
\n Lotilaner Ophthalmic Solution, 0.25% for the Treatment of <\/strong>
\n
\n Demodex<\/em>
\n <\/strong>
\n blepharitis Patients with Meibomian Gland Dysfunction<\/strong>
\n <\/a>
\n
\n Date: Monday, April 28, 2025, 8:33 \u2013 8:38 a.m. PT<\/strong>
\n
\n Location: LACC \u2013 Level 2, 506<\/strong>
\n
\n Presenter: Mitchell C. Schultz, M.D., ABO<\/strong>
\n
Two pooled studies that evaluated the safety and efficacy of XDEMVY in patients with Demodex<\/em> blepharitis and Meibomian Gland Disease.<\/p>\n

\n
\n Prevalence of <\/strong>
\n
\n Demodex<\/em>
\n <\/strong>
\n blepharitis in Japan: The Elara Study<\/strong>
\n <\/a>
\n
\n Date: Monday, April 28, 2025, 10:30 \u2013 10:35 a.m. PT<\/strong>
\n
\n Location: LACC \u2013 Level 2, 504<\/strong>
\n
\n Presenter: Shizuka Koh, M.D., Ph.D.<\/strong>
\n
An observational, multicenter study highlighting the prevalence and symptomatology of Demodex<\/em> blepharitis in Japan.<\/p>\n

\n About <\/strong>
\n
\n Demodex<\/em>
\n <\/strong>
\n Blepharitis<\/strong>
\n
Blepharitis is a common lid margin disease that is characterized by eyelid margin inflammation, redness and ocular irritation.\u00a0Demodex<\/em>\u00a0blepharitis is caused by an infestation of\u00a0Demodex<\/em>\u00a0mites, the most common ectoparasite found on humans, and accounts for over two-thirds of all blepharitis cases.\u00a0Demodex<\/em>\u00a0blepharitis may affect as many as 25 million Americans based on an extrapolation from the Titan study indicating 58% of patients presenting to U.S. eye care clinics have collarettes, a pathognomonic sign of\u00a0Demodex<\/em>\u00a0mite infestation, and that at least 45 million people annually visit an eye care clinic.\u00a0Demodex\u00a0<\/em>blepharitis can have a significant clinical burden and negative impact on patients\u2019 daily lives.<\/p>\n

\n About XDEMVY<\/strong>
\n
\n \u00ae<\/strong>
\n <\/sup>
\n
XDEMVY (lotilaner ophthalmic solution) 0.25%, formerly known as TP-03, is a novel prescription eye drop designed to treat\u00a0Demodex<\/em>\u00a0blepharitis by targeting and eradicating the root cause of the disease \u2013\u00a0Demodex<\/em>\u00a0mite infestation. XDEMVY was evaluated in two pivotal trials collectively involving more than 800 patients. Both trials met the primary endpoint and all secondary endpoints, with statistical significance and no serious treatment-related adverse events. Most patients found the XDEMVY eye drop to be neutral to very comfortable. The most common ocular adverse reactions observed in the studies were instillation site stinging and burning which was reported in 10% of patients. Other ocular adverse reactions reported by less than 2% of patients were chalazion\/hordeolum (stye) and punctate keratitis.<\/p>\n

\n XDEMVY Indication and Important Safety Information<\/strong>\n <\/p>\n

\n Indications and Usage<\/strong>\n <\/p>\n

XDEMVY (lotilaner ophthalmic solution) 0.25% is indicated for the treatment of\u00a0Demodex\u00a0<\/em>blepharitis.<\/p>\n

\n Important Safety Information<\/strong>\n <\/p>\n

\n Most common side effects:<\/strong>\u00a0The most common side effect in clinical trials was stinging and burning in 10% of patients. Other side effects in less than 2% of patients were chalazion\/hordeolum and punctate keratitis.<\/p>\n

\n Handling the Container:<\/strong>\u00a0Avoid allowing the tip of the dispensing container to contact the eye, surrounding structures, fingers, or any other surface in order to minimize contamination of the solution. Serious damage to the eye and subsequent loss of vision may result from using contaminated solutions.<\/p>\n

\n When to Seek Physician Advice<\/strong>: Immediately seek a physician\u2019s advice concerning the continued use of XDEMVY if you develop an intercurrent ocular condition (e.g., trauma or infection), have ocular surgery, or develop any ocular reactions, particularly conjunctivitis and eyelid reactions.<\/p>\n

\n Use with Contact Lenses:<\/strong>\u00a0XDEMVY contains potassium sorbate, which may discolor soft contact lenses. Contact lenses should be removed prior to instillation of XDEMVY and may be reinserted 15 minutes following its administration.<\/p>\n

To report SUSPECTED ADVERSE REACTIONS, contact Tarsus Pharmaceuticals at 1-888-421-4002 or FDA at 1-800-FDA-1088 or\u00a0www.fda.gov\/medwatch<\/a>.<\/p>\n

For additional information please see\u00a0Full Prescribing Information<\/a>\u00a0available at:\u00a0www.xdemvy.com<\/a>.<\/p>\n

\n About Tarsus Pharmaceuticals, Inc.<\/strong>
\n
Tarsus Pharmaceuticals, Inc. applies proven science and new technology to revolutionize treatment for patients, starting with eye care. Tarsus is advancing its pipeline to address several diseases with high unmet need across a range of therapeutic categories, including eye care and infectious disease prevention.\u00a0XDEMVY\u2122 (lotilaner ophthalmic solution) 0.25%, is FDA approved in the United States for the treatment of Demodex blepharitis. Tarsus is also developing TP-04 for the potential treatment of Ocular Rosacea and TP-05 as an oral tablet for the potential prevention of Lyme disease.<\/p>\n

\n Forward-Looking Statements<\/strong>
\n
Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute \u201cforward-looking statements.\u201d These statements include statements regarding the timing, content, location, and presenters of scientific abstracts at an upcoming medical conference, our ability to continue to educate the market and generate data about\u00a0Demodex<\/em>\u00a0blepharitis, the potential market size of Demodex<\/em>\u00a0blepharitis globally, and the quotations of Tarsus\u2019 management.\u00a0The words, without limitation, \u201cbelieve,\u201d \u201ccontemplate,\u201d \u201ccontinue,\u201d \u201ccould,\u201d \u201cestimate,\u201d \u201cexpect,\u201d \u201cintend,\u201d \u201cmay,\u201d \u201cmight,\u201d \u201cplan,\u201d \u201cpotential,\u201d \u201cpredict,\u201d \u201cproject,\u201d \u201cshould,\u201d \u201ctarget,\u201d \u201cwill,\u201d or \u201cwould,\u201d or the negative of these terms or other similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these or similar identifying words. Further, there are other risks and uncertainties that could cause actual results to differ from those set forth in the forward-looking statement and they are detailed from time to time in the reports Tarsus files with the Securities and Exchange Commission, including Tarsus\u2019 Form 10-K for the year ended December 31, 2024, filed on February 25, 2025, with the SEC, copies of which are posted on its website and are available from Tarsus without charge. However, new risk factors and uncertainties may emerge from time to time, and it is not possible to predict all risk factors and uncertainties. Accordingly, readers are cautioned not to place undue reliance on these forward-looking statements. Any forward-looking statements contained in this press release are based on the current expectations of Tarsus\u2019 management team and speak only as of the date hereof, and Tarsus specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.<\/p>\n

\n Contacts:<\/strong>
\n
\n Media Contact:<\/u>
\n
Adrienne Kemp
Sr. Director, Corporate Communications
(949) 922-0801
akemp@tarsusrx.com<\/a><\/p>\n

\n Investor Contact:<\/u>
\n
David Nakasone
Head of Investor Relations
(949) 620-3223
DNakasone@tarsusrx.com<\/a><\/p>\n

\"\"
\n
\n \"\"\n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

IRVINE, Calif., April 22, 2025 (GLOBE NEWSWIRE) — Tarsus Pharmaceuticals, Inc. (NASDAQ: TARS) will present four distinct data sets highlighting the global prevalence and real-world patient burden of Demodex blepharitis, as well as the impact of XDEMVY\u00ae (lotilaner ophthalmic solution) 0.25% in addressing objective measures of disease at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting, taking place April 25-28, 2025, in Los Angeles, Calif. \u201cFrom new prevalence data in Japan to real-world results in the US, the findings accepted for oral presentation at ASCRS reinforce the global burden of Demodex blepharitis and the potential of XDEMVY to deliver significant improvements in patient outcomes across multiple subtypes, including those with concomitant meibomian gland disease,\u201d said Elizabeth … <\/p>\n

Continue reading “Tarsus to Present Several Scientific Abstracts Highlighting the Global Prevalence of Demodex Blepharitis and the Clinical Impact of XDEMVY at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-839994","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nTarsus to Present Several Scientific Abstracts Highlighting the Global Prevalence of Demodex Blepharitis and the Clinical Impact of XDEMVY at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tarsus to Present Several Scientific Abstracts Highlighting the Global Prevalence of Demodex Blepharitis and the Clinical Impact of XDEMVY at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"IRVINE, Calif., April 22, 2025 (GLOBE NEWSWIRE) — Tarsus Pharmaceuticals, Inc. 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(NASDAQ: TARS) will present four distinct data sets highlighting the global prevalence and real-world patient burden of Demodex blepharitis, as well as the impact of XDEMVY\u00ae (lotilaner ophthalmic solution) 0.25% in addressing objective measures of disease at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting, taking place April 25-28, 2025, in Los Angeles, Calif. \u201cFrom new prevalence data in Japan to real-world results in the US, the findings accepted for oral presentation at ASCRS reinforce the global burden of Demodex blepharitis and the potential of XDEMVY to deliver significant improvements in patient outcomes across multiple subtypes, including those with concomitant meibomian gland disease,\u201d said Elizabeth … Continue reading \"Tarsus to Present Several Scientific Abstracts Highlighting the Global Prevalence of Demodex Blepharitis and the Clinical Impact of XDEMVY at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/","og_site_name":"Market Newsdesk","article_published_time":"2025-04-22T12:57:04+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQzNjQyNiM2ODk2Mjc5IzIyMDM4NjQ=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Tarsus to Present Several Scientific Abstracts Highlighting the Global Prevalence of Demodex Blepharitis and the Clinical Impact of XDEMVY at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting","datePublished":"2025-04-22T12:57:04+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/"},"wordCount":1224,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTQzNjQyNiM2ODk2Mjc5IzIyMDM4NjQ=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/tarsus-to-present-several-scientific-abstracts-highlighting-the-global-prevalence-of-demodex-blepharitis-and-the-clinical-impact-of-xdemvy-at-the-american-society-of-cataract-and-refractive-surgery-a\/","name":"Tarsus to Present Several Scientific Abstracts Highlighting the Global Prevalence of Demodex Blepharitis and the Clinical Impact of XDEMVY at the American Society of Cataract and Refractive Surgery (ASCRS) 2025 Annual Meeting - 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