{"id":831830,"date":"2025-03-31T14:03:24","date_gmt":"2025-03-31T18:03:24","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/new-data-confirm-rapid-unpredictable-progression-of-severe-aortic-stenosis-and-need-for-urgent-referral-and-evaluation-of-patients\/"},"modified":"2025-03-31T14:03:24","modified_gmt":"2025-03-31T18:03:24","slug":"new-data-confirm-rapid-unpredictable-progression-of-severe-aortic-stenosis-and-need-for-urgent-referral-and-evaluation-of-patients","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/new-data-confirm-rapid-unpredictable-progression-of-severe-aortic-stenosis-and-need-for-urgent-referral-and-evaluation-of-patients\/","title":{"rendered":"New Data Confirm Rapid, Unpredictable Progression of Severe Aortic Stenosis and Need for Urgent Referral and Evaluation of Patients"},"content":{"rendered":"

<\/p>\n

New Data Confirm Rapid, Unpredictable Progression of Severe Aortic Stenosis and Need for Urgent Referral and Evaluation of Patients<\/b><\/p>\n

CHICAGO–(BUSINESS WIRE<\/a>)–
\nEdwards Lifesciences (NYSE: EW) today announced new scientific evidence presented and published during the American College of Cardiology\u2019s (ACC) Annual Scientific Session & Expo, addressing the critical needs of patients with structural heart disease.\n<\/p>\n

\nWithout treatment, 1 in 10 patients experiencing symptoms of severe aortic stenosis (AS) may die within five weeks. However, the symptoms of severe AS can be difficult to detect and may progress rapidly and unpredictably. New data presented at ACC underscore the importance of urgently referring patients to a heart team for evaluation once diagnosed.\n<\/p>\n

\nAmong the groundbreaking data were findings from the randomized, controlled DETECT AS study, the first to evaluate the impact of automatic electronic provider notifications (echo alerts) for patients with severe AS. In this trial involving 939 patients and 285 physicians, those who ordered an echo for severe AS were randomized to either receive an echo alert describing treatment guidelines or no notification. The findings revealed echo alerts increased aortic valve replacement (AVR) treatment rates by 11 percent for all patients with severe AS, and 14 percent for symptomatic severe AS patients. Echo alerts also significantly improved AVR treatment rates among older patients and women, thereby reducing age and gender disparities. The results were simultaneously published in Circulation<\/i>.\n<\/p>\n

\n\u201cThese data illuminate the persistent under-referral and under-treatment of severe AS patients and the significant impact a critical echo notification can have on improving treatment of this deadly disease,\u201d said Sammy Elmariah, M.D., Interventional Cardiology Medical Director, Cardiac Catheterization Laboratory, and associate professor at the University of California, San Francisco.\n<\/p>\n

\nAdditional insights from the EARLY TAVR trial were also presented at ACC. The EARLY TAVR trial was the first randomized, controlled FDA pivotal study designed to determine the best strategy for treating asymptomatic severe AS and the benefits of timely intervention with TAVR. The data were published in The<\/i>New England Journal of Medicine<\/i> and demonstrated that asymptomatic severe AS patients randomized to Edwards TAVR experienced superior outcomes compared with guideline-recommended clinical surveillance (watchful waiting), with no clinical penalty for timely intervention.\n<\/p>\n

\nThe new study presented at ACC evaluated outcomes of patients treated in the EARLY TAVR trial segmented by the severity of their signs and symptoms once they converted to AVR. These data reiterate that watchful waiting is not an effective strategy for the management of severe AS.\n<\/p>\n

\nIn addition, it was hypothesized that cardiac biomarkers may be predictive of the best time for severe AS patients to go from watchful waiting to receiving treatment. Another new study presented at ACC showed that biomarkers were not predictive, further underscoring the rapid and unpredictable progression of the disease and urgency to refer patients to a heart team for evaluation and treatment. Results of the biomarkers study were simultaneously published in Circulation<\/i>.\n<\/p>\n

\n\u201cThe data from these new studies confirm that severe aortic stenosis is a complex disease and reiterate the need for urgent referral and evaluation of treatment for patients with or without symptoms,\u201d said Larry Wood, Edwards\u2019 corporate vice president and group president, transcatheter aortic valve replacement and surgical structural heart. \u201cWe remain committed to advancing high-quality science and delivering life-saving structural heart therapies for patients with our leading SAPIEN valve platform, which has been used to treat more than 1 million patients worldwide.”\n<\/p>\n

About Edwards Lifesciences<\/b><\/p>\n

\nEdwards Lifesciences is the leading global structural heart innovation company, driven by a passion to improve patient lives. Through breakthrough technologies, world-class evidence and partnerships with clinicians and healthcare stakeholders, our employees are inspired by our patient-focused culture to deliver life-changing innovations to those who need them most. Discover more at www.edwards.com<\/a> and follow us on LinkedIn<\/a>, Facebook<\/a>, Instagram<\/a> and YouTube<\/a>.\n<\/p>\n

\nThis news release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. We intend the forward-looking statements contained in this release to be covered by the safe harbor provisions of such Acts. These forward-looking statements can sometimes be identified by the use of forward-looking words, such as \u201cmay,\u201d \u201cmight,\u201d \u201cbelieve,\u201d \u201cwill,\u201d \u201cexpect,\u201d \u201cproject,\u201d \u201cestimate,\u201d \u201cshould,\u201d \u201canticipate,\u201d \u201cplan,\u201d \u201cgoal,\u201d \u201ccontinue,\u201d \u201cseek,\u201d \u201cintend,\u201d \u201coptimistic,\u201d \u201caspire,\u201d \u201cconfident\u201d and other forms of these words and include, but are not limited to, statements made by Mr. Wood and Dr. Elmariah and statements regarding expected product benefits, including patient outcomes, objectives and expectations and other statements that are not historical facts. Forward-looking statements are based on estimates and assumptions made by management of the company and are believed to be reasonable, though they are inherently uncertain and difficult to predict. Our forward-looking statements speak only as of the date on which they are made, and we do not undertake any obligation to update any forward-looking statement to reflect events or circumstances after the date of the statement. Investors are cautioned not to unduly rely on such forward-looking statements.\n<\/p>\n

\nForward-looking statements involve risks and uncertainties that could cause results to differ materially from those expressed or implied by the forward-looking statements based on a number of factors as detailed in the company’s filings with the Securities and Exchange Commission. These filings, along with important safety information about our products, may be found at Edwards.com.\n<\/p>\n

\nEdwards, Edwards Lifesciences, the stylized E logo, and EARLY TAVR are trademarks of Edwards Lifesciences Corporation or its affiliates. All other trademarks are the property of their respective owners.\n<\/p>\n

\"\"<\/p>\n

View source version on businesswire.com: <\/span>https:\/\/www.businesswire.com\/news\/home\/20250331142473\/en\/<\/a><\/span><\/p>\n

\nMedia Contact: Heather Bukant, 949-250-2753
\n
Investor Contact: Mark Wilterding, 949-250-6826\n<\/p>\n

KEYWORDS:<\/b> United States North America Illinois<\/p>\n

INDUSTRY KEYWORDS:<\/b> Biotechnology Health Cardiology Medical Devices<\/p>\n

MEDIA:<\/b><\/p>\n\n\n\n\n
Logo<\/b><\/font><\/td>\n<\/tr>\n
\"Logo\"<\/td>\n<\/tr>\n
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New Data Confirm Rapid, Unpredictable Progression of Severe Aortic Stenosis and Need for Urgent Referral and Evaluation of Patients CHICAGO–(BUSINESS WIRE)– Edwards Lifesciences (NYSE: EW) today announced new scientific evidence presented and published during the American College of Cardiology\u2019s (ACC) Annual Scientific Session & Expo, addressing the critical needs of patients with structural heart disease. Without treatment, 1 in 10 patients experiencing symptoms of severe aortic stenosis (AS) may die within five weeks. However, the symptoms of severe AS can be difficult to detect and may progress rapidly and unpredictably. New data presented at ACC underscore the importance of urgently referring patients to a heart team for evaluation once diagnosed. Among the groundbreaking data were findings from the randomized, controlled … <\/p>\n

Continue reading “New Data Confirm Rapid, Unpredictable Progression of Severe Aortic Stenosis and Need for Urgent Referral and Evaluation of Patients”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-831830","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nNew Data Confirm Rapid, Unpredictable Progression of Severe Aortic Stenosis and Need for Urgent Referral and Evaluation of Patients - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/new-data-confirm-rapid-unpredictable-progression-of-severe-aortic-stenosis-and-need-for-urgent-referral-and-evaluation-of-patients\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Data Confirm Rapid, Unpredictable Progression of Severe Aortic Stenosis and Need for Urgent Referral and Evaluation of Patients - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"New Data Confirm Rapid, Unpredictable Progression of Severe Aortic Stenosis and Need for Urgent Referral and Evaluation of Patients CHICAGO–(BUSINESS WIRE)– Edwards Lifesciences (NYSE: EW) today announced new scientific evidence presented and published during the American College of Cardiology\u2019s (ACC) Annual Scientific Session & Expo, addressing the critical needs of patients with structural heart disease. Without treatment, 1 in 10 patients experiencing symptoms of severe aortic stenosis (AS) may die within five weeks. However, the symptoms of severe AS can be difficult to detect and may progress rapidly and unpredictably. New data presented at ACC underscore the importance of urgently referring patients to a heart team for evaluation once diagnosed. 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Without treatment, 1 in 10 patients experiencing symptoms of severe aortic stenosis (AS) may die within five weeks. However, the symptoms of severe AS can be difficult to detect and may progress rapidly and unpredictably. New data presented at ACC underscore the importance of urgently referring patients to a heart team for evaluation once diagnosed. 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