{"id":828795,"date":"2025-03-24T07:12:15","date_gmt":"2025-03-24T11:12:15","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/"},"modified":"2025-03-24T07:12:15","modified_gmt":"2025-03-24T11:12:15","slug":"entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/","title":{"rendered":"Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"center\">\n        <em>\u2013 Company on track to initiate ELEVATE-45-201 study in Q3 2025 \u2013<\/em>\n      <\/p>\n<p align=\"center\">\n        <em>\u2013 ELEVATE-45 regulatory filings submitted in the EU, with regulatory review ongoing \u2013<\/em>\n      <\/p>\n<p align=\"center\">\n        <em>\u00a0\u2013 ELEVATE-45 is the second of three novel exon skipping Duchenne programs the Company expects to progress into global clinical development in 2025 \u2013<\/em>\n      <\/p>\n<p>BOSTON, March  24, 2025  (GLOBE NEWSWIRE) &#8212; Entrada Therapeutics, Inc. (Nasdaq: TRDA) today announced it has received authorization from the United Kingdom\u2019s Medicines and Healthcare Products Regulatory Agency (MHRA) and Research Ethics Committee to initiate ELEVATE-45-201. ELEVATE-45-201 is a Phase 1\/2 multiple ascending dose (MAD) clinical study to evaluate Entrada\u2019s investigational medicinal product ENTR-601-45 for the potential treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation in the <em>DMD<\/em> gene amenable to exon 45 skipping.<\/p>\n<p>\u201cWe are pleased to receive U.K. clearance for the second clinical program in our growing Duchenne franchise. Building on the momentum of our ELEVATE-44 program, this authorization brings us closer to having three Duchenne programs in clinical development by the end of this year,\u201d said Dipal Doshi, Chief Executive Officer of Entrada Therapeutics. \u201cFor people living with progressive diseases, every moment counts. To meet this urgency in Duchenne, we will continue our strategy of initiating and running studies in the U.K. and EU before sharing these study results with the FDA to potentially enable registrational studies in the U.S.&#8221;<\/p>\n<p>ELEVATE-45-201 is a global, two-part, randomized, double-blind placebo-controlled Phase 1\/2 study evaluating the safety, tolerability and effectiveness of ENTR-601-45 in ambulatory patients with Duchenne who are exon 45 skipping amenable. Part A is a multiple ascending dose study designed to evaluate the safety, pharmacokinetics and pharmacodynamics, including exon skipping and dystrophin production in approximately 24 patients. Dosing will be administered every six weeks, with the planned doses across three cohorts anticipated to range from 5 mg\/kg up to 15 mg\/kg. Part B of the study is designed to further evaluate the optimal dose established in Part A for safety and efficacy, including functional outcomes and patient reported quality of life measures. Study participants may be eligible to enter an open label extension study (OLE), in which the safety, efficacy and tolerability of ENTR-601-45 will be evaluated over a longer period of time. The Company is on track to initiate ELEVATE-45-201 in Q3 2025.<\/p>\n<p>\n        <strong>About ENTR-601-45<\/strong><br \/>\n        <br \/>ENTR-601-45, a proprietary Endosomal Escape Vehicle (EEV\u2122)-conjugated phosphorodiamidate morpholino oligomer (PMO), is the second product candidate within Entrada\u2019s Duchenne muscular dystrophy franchise from its growing pipeline of EEV-therapeutics. Each EEV-PMO therapeutic candidate has an oligonucleotide sequence designed and optimized for the specific subpopulation of interest. ENTR-601-45 is designed to address the underlying cause of Duchenne due to mutated or missing exons in the <em>DMD<\/em> gene. ENTR-601-45, an investigational therapy for the potential treatment of people living with Duchenne who are exon 45 skipping amenable, is being evaluated for its potential to restore the mRNA reading frame and allow for the translation of dystrophin protein that is slightly shortened but still functional.<\/p>\n<p>\n        <strong>About Duchenne Muscular Dystrophy (DMD)<\/strong><br \/>\n        <br \/>Duchenne muscular dystrophy (DMD) is a rare disease caused by mutations in the\u00a0<em>DMD<\/em>\u00a0gene, which encodes for the dystrophin protein. These mutations lead to inadequate dystrophin production. Dystrophin is essential to maintaining the structural integrity and function of muscle cells. Lack of functional dystrophin leads to progressive loss of muscle strength, impacting mobility and causing heart or respiratory complications that contribute to high mortality rates. An estimated 41,000 people in the U.S. and Europe have Duchenne.<\/p>\n<p>\n        <strong>About Entrada Therapeutics<\/strong><br \/>\n        <br \/>Entrada Therapeutics is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. The Company\u2019s Endosomal Escape Vehicle (EEV\u2122)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others. The Company\u2019s lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.<\/p>\n<p>For more information about Entrada, please visit our website, <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=ZeTP7_1FLb5jTebV-lSAwzGXs21m_z0k3cDlOPXK56fVCquM9aBzqUA4jIqIaJp0dzvy2H2YbShM1GqlrYFGBNHaXKhTchRJVb47Z-LQqxs=\" rel=\"nofollow\" target=\"_blank\">www.entradatx.com<\/a>, and follow us on <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=xgPDXLhx9A875lrjgSnr_5bkA2lmZCyuYT5VusKwkhQOpt-UNC6VYi5LsTSVeY10EmzUTIMoNNpsQ-bR0xr52GvJAT3NGzVXUtKHgO8MpUg=\" rel=\"nofollow\" target=\"_blank\">LinkedIn<\/a>.<\/p>\n<p>\n        <strong>Forward-Looking Statements<\/strong><br \/>\n        <br \/>This press release contains express and implied forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, contained in this press release, including statements regarding Entrada\u2019s strategy, future operations, prospects and plans, objectives of management, the validation and differentiation of Entrada\u2019s approach and EEV platform and its ability to provide a potential treatment for patients, expectations regarding Entrada\u2019s planned Phase 1\/2 MAD clinical study of ENTR-601-45, including its initiation in the United Kingdom in Q3 2025, the expectations about the planned dosing levels of the planned Phase 1\/2 trial for ENTR-601-45 and their efficacy, the ability to recruit for and complete a global Phase 1\/2 trial for ENTR-601-45 and the anticipated number of patients to be enrolled, the potential of Entrada\u2019s EEV product candidates, including the potential for ENTR-601-45 to be a transformative treatment option, and the continued development and advancement of ENTR-601-45 for the potential treatment of DMD, constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. The words \u201canticipate,\u201d \u201cbelieve,\u201d \u201ccontinue,\u201d \u201ccould,\u201d \u201cestimate,\u201d \u201cexpect,\u201d \u201cintend,\u201d \u201cmay,\u201d \u201cmight,\u201d \u201cobjective,\u201d \u201congoing,\u201d \u201cplan,\u201d \u201cpredict,\u201d \u201cproject,\u201d \u201cpotential,\u201d \u201cshould,\u201d or \u201cwould,\u201d or the negative of these terms, or other comparable terminology are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Entrada may not actually achieve the plans, intentions or expectations disclosed in these forward-looking statements, and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various important factors, including: uncertainties inherent in the identification and development of product candidates, including the conduct of research activities and the initiation and completion of preclinical studies and clinical trials; uncertainties as to the availability and timing of results from preclinical and clinical studies; the timing of and Entrada\u2019s ability to submit and obtain regulatory clearance and initiate clinical trials; whether results from preclinical studies or clinical trials will be predictive of the results of later preclinical studies and clinical trials; whether Entrada\u2019s cash resources will be sufficient to fund the Company\u2019s foreseeable and unforeseeable operating expenses and capital expenditure requirements; as well as the risks and uncertainties identified in Entrada\u2019s filings with the Securities and Exchange Commission (SEC), including the Company\u2019s Annual Report on Form 10-K for the fiscal year and quarter ended December 31, 2024 and in subsequent filings Entrada may make with the SEC. In addition, the forward-looking statements included in this press release represent Entrada\u2019s views as of the date of this press release. Entrada anticipates that subsequent events and developments will cause its views to change. However, while Entrada may elect to update these forward-looking statements at some point in the future, it specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Entrada\u2019s views as of any date subsequent to the date of this press release.<\/p>\n<p>\n        <strong>Investor and Media Contact<\/strong><br \/>\n        <br \/>Caileigh Dougherty<br \/>Head of Investor Relations &amp; Corporate Communications<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=RSIj2Lh56OBrBUXpVaKHtnxclJU9HfVIuGTD06jsm875rzL7xKNcUX7O0UaOa8lhoCuxBuXA7reqv6YnkD2BPz5_wZnLOCMbYNdiG9SL-mO3syuq_dE23zVbuJWTWpFw\" rel=\"nofollow\" target=\"_blank\">cdougherty@entradatx.com<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTM5OTAzMSM2ODE5MDE1IzIyMDA1MzI=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/NTg2ZGM0M2YtZTI3Ni00NzI1LWIyZWItNDE3MzIyYTEzNjMxLTEyMTIwODUtMjAyNS0wMy0yNC1lbg==\/tiny\/Entrada-Therapeutics-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u2013 Company on track to initiate ELEVATE-45-201 study in Q3 2025 \u2013 \u2013 ELEVATE-45 regulatory filings submitted in the EU, with regulatory review ongoing \u2013 \u00a0\u2013 ELEVATE-45 is the second of three novel exon skipping Duchenne programs the Company expects to progress into global clinical development in 2025 \u2013 BOSTON, March 24, 2025 (GLOBE NEWSWIRE) &#8212; Entrada Therapeutics, Inc. (Nasdaq: TRDA) today announced it has received authorization from the United Kingdom\u2019s Medicines and Healthcare Products Regulatory Agency (MHRA) and Research Ethics Committee to initiate ELEVATE-45-201. ELEVATE-45-201 is a Phase 1\/2 multiple ascending dose (MAD) clinical study to evaluate Entrada\u2019s investigational medicinal product ENTR-601-45 for the potential treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation in the &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-828795","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"\u2013 Company on track to initiate ELEVATE-45-201 study in Q3 2025 \u2013 \u2013 ELEVATE-45 regulatory filings submitted in the EU, with regulatory review ongoing \u2013 \u00a0\u2013 ELEVATE-45 is the second of three novel exon skipping Duchenne programs the Company expects to progress into global clinical development in 2025 \u2013 BOSTON, March 24, 2025 (GLOBE NEWSWIRE) &#8212; Entrada Therapeutics, Inc. (Nasdaq: TRDA) today announced it has received authorization from the United Kingdom\u2019s Medicines and Healthcare Products Regulatory Agency (MHRA) and Research Ethics Committee to initiate ELEVATE-45-201. ELEVATE-45-201 is a Phase 1\/2 multiple ascending dose (MAD) clinical study to evaluate Entrada\u2019s investigational medicinal product ENTR-601-45 for the potential treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation in the &hellip; Continue reading &quot;Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-03-24T11:12:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTM5OTAzMSM2ODE5MDE1IzIyMDA1MzI=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\\\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping\",\"datePublished\":\"2025-03-24T11:12:15+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\\\/\"},\"wordCount\":1284,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTM5OTAzMSM2ODE5MDE1IzIyMDA1MzI=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\\\/\",\"name\":\"Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\\\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/","og_locale":"en_US","og_type":"article","og_title":"Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping - Market Newsdesk","og_description":"\u2013 Company on track to initiate ELEVATE-45-201 study in Q3 2025 \u2013 \u2013 ELEVATE-45 regulatory filings submitted in the EU, with regulatory review ongoing \u2013 \u00a0\u2013 ELEVATE-45 is the second of three novel exon skipping Duchenne programs the Company expects to progress into global clinical development in 2025 \u2013 BOSTON, March 24, 2025 (GLOBE NEWSWIRE) &#8212; Entrada Therapeutics, Inc. (Nasdaq: TRDA) today announced it has received authorization from the United Kingdom\u2019s Medicines and Healthcare Products Regulatory Agency (MHRA) and Research Ethics Committee to initiate ELEVATE-45-201. ELEVATE-45-201 is a Phase 1\/2 multiple ascending dose (MAD) clinical study to evaluate Entrada\u2019s investigational medicinal product ENTR-601-45 for the potential treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation in the &hellip; Continue reading \"Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/","og_site_name":"Market Newsdesk","article_published_time":"2025-03-24T11:12:15+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTM5OTAzMSM2ODE5MDE1IzIyMDA1MzI=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping","datePublished":"2025-03-24T11:12:15+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/"},"wordCount":1284,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTM5OTAzMSM2ODE5MDE1IzIyMDA1MzI=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/entrada-therapeutics-receives-authorization-in-the-united-kingdom-to-initiate-elevate-45-201-a-phase-1-2-multiple-ascending-dose-clinical-study-of-entr-601-45-in-people-living-with-duchenne-muscular\/","name":"Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate ELEVATE-45-201, a Phase 1\/2 Multiple Ascending Dose Clinical Study of ENTR-601-45 in People Living with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping - 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