{"id":827478,"date":"2025-03-19T08:34:00","date_gmt":"2025-03-19T12:34:00","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/"},"modified":"2025-03-19T08:34:00","modified_gmt":"2025-03-19T12:34:00","slug":"tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/","title":{"rendered":"Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session"},"content":{"rendered":"<h2>\nLate Breaker Oral Presentation to Include New Data from Cohort 1 of the MyPEAK\u2122-1 Phase 1b\/2 Clinical Trial of TN-201<br \/>\n<\/h2>\n<div class=\"mw_release\">\n<p align=\"justify\">SOUTH SAN FRANCISCO, Calif., March  19, 2025  (GLOBE NEWSWIRE) &#8212; Tenaya Therapeutics, Inc. (NASDAQ: TNYA), a clinical-stage biotechnology company with a mission to discover, develop and deliver potentially curative therapies that address the underlying causes of heart disease, today announced that new clinical and disease burden data pertaining to the company\u2019s <em>MYBPC3<\/em>-associated hypertrophic cardiomyopathy (HCM) program will be presented at the upcoming American College of Cardiology\u2019s Annual Scientific Session being held March 29-31, 2025 in Chicago, IL.<\/p>\n<p align=\"justify\">Tenaya is advancing TN-201, an AAV9-based gene therapy for the potential treatment of <em>MYBPC3<\/em>-associated HCM, a condition caused by insufficient levels of myosin-binding protein C (MyBP-C). As part of the late-breaking Clinical and Investigative Horizons session on Monday, March 31, data from the first cohort of adult patients enrolled in the MyPEAK-1 Phase 1b\/2 clinical trial will be featured. Building on early encouraging data shared in December 2024, the presentation at ACC will include results from one-year assessments of the first two patients to receive TN-201 gene therapy, and baseline biopsy and six-month assessments from the third patient in the 3E13 vg\/kg cohort. These data will be presented by Milind Desai, M.D., M.B.A, Haslam Family Endowed Chair in Cardiovascular Medicine, Vice Chair, Heart Vascular Thoracic Institute, Director of the Hypertrophic Cardiomyopathy Center at the Cleveland Clinic, and an investigator for the MyPEAK-1 Phase 1b\/2 clinical trial.<\/p>\n<p align=\"justify\">A poster presentation on Sunday, March 30, will detail findings from SHaRe (Sarcomeric Human Cardiomyopathy Registry), describing differences in disease burden among adults with HCM caused by <em>MYBPC3<\/em> mutations.<\/p>\n<p>Details of the presentations are as follows:<\/p>\n<p>\n        <em>Sunday, March 30, 2025<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li>\n          <strong>Poster:<\/strong> Differences in Patient Characteristics and Burden of Disease in Adults with MYBPC3-Associated HCM (#129)<\/li>\n<li>\n          <strong>Presenting author:<\/strong> Whit Tingley, M.D., Ph.D., Tenaya Therapeutics<\/li>\n<li>\n          <strong>Session 1152:<\/strong> Heart Failure and Cardiomyopathies<\/li>\n<li>\n          <strong>Time and location:<\/strong> 10:30 am \u2013 11:30 am CT; South Hall<\/li>\n<\/ul>\n<p>\n        <em>Monday, March 31, 2025 &#8211; <\/em><br \/>\n        <strong>ACC Late-breaking presentation <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li>\n          <strong>Presentation: <\/strong>First Report of Phase Ib\/2a Study Evaluating Safety and Early Efficacy of TN-201, an Adeno-Associated Virus Serotype 9 Gene Replacement Therapy, in Adults with <em>MYBPC3<\/em>-Associated Hypertrophic Cardiomyopathy (abstract ##)<\/li>\n<li>\n          <strong>Presenting author:<\/strong> Dr. Milind Desai, M.D., M.B.A., Cleveland Clinic<\/li>\n<li>\n          <strong>Session 402:<\/strong> Heart Failure and Cardiomyopathies<\/li>\n<li>\n          <strong>Time and location:<\/strong> 9:00 am \u2013 10:00 am CT; S100B<\/li>\n<\/ul>\n<p align=\"justify\">To view full event programming, please visit the ACC.25 <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=3QWoM8G3KPiLntB_j5gppE-VXyxIgKUKgWwpw0Z9uWvkhjbCHEG4oR0gz8mvsktVyAhObNwR2eLIIV7sN7oi0oVvXjsq0WUEWgssu0MRJzU=\" rel=\"nofollow\" target=\"_blank\">website<\/a>. Following the conference, Tenaya\u2019s presentations will be available in the \u201cOur Science\u201d section of the company\u2019s <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=3QWoM8G3KPiLntB_j5gppM56XwyGnsqz9xlyOX4wpLB-DLyxDqbj6xAjt109QhKVOPv_YbUZApz1NBRKDhFYZtxz8XhrL8ex-SlhmpZ5EoSoAMXSQXVSdmOnXvZMz9Ak\" rel=\"nofollow\" target=\"_blank\">website<\/a>.<\/p>\n<p align=\"justify\">\n        <strong>About\u00a0Tenaya Therapeutics<\/strong><br \/>\n        <br \/>Tenaya Therapeutics is a clinical-stage biotechnology company committed to a bold mission: to discover, develop and deliver potentially curative therapies that address the underlying drivers of heart disease. Leveraging integrated proprietary core capabilities enabling target identification and validation, design of AAV-based genetic medicines and in-house manufacturing the company is advancing a pipeline of novel therapies with diverse treatment modalities for rare genetic cardiovascular disorders and more prevalent heart conditions. Tenaya\u2019s most advanced candidates include TN-201, a gene therapy for\u00a0<em>MYBPC3<\/em>-associated hypertrophic cardiomyopathy (HCM), TN-401, a gene therapy for\u00a0<em>PKP2<\/em>-associated arrhythmogenic right ventricular cardiomyopathy (ARVC), and TN-301, a small molecule HDAC6 inhibitor being initially developed for heart failure with preserved ejection fraction (HFpEF). Tenaya also has multiple early-stage programs progressing through preclinical development. For more information, visit\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=YcoeXyOZKGIBpH25v7l_aSTtWwsfAsrtMsvwRNDvXw9fgT8RxqPK4bALh8nQMyu3MUFewqONWxDyn3XLaJGxI4zxOkJRzrIawJEWOj0aKWGdEyGJj7XH6S967GaWzOzs5As023A7AKNRh8aKlV0Ar9uq0OoONVktr9-w-YB1rh-I2XiHuItNkhlqqplrqf5GU8HTaoF5SkACDVs0Di9UbZ9U4Nnr_DgVJKcmA5w1tKMwsmYCZHUUkAAIM5UZiLOyfCavpyYFDKspskMP3lWrRStw2pcSeDoBqLCthXWGYwU=\" rel=\"nofollow\" target=\"_blank\">www.tenayatherapeutics.com<\/a>.<\/p>\n<p>\n        <strong>Contact <\/strong><br \/>\n        <br \/>Michelle Corral<br \/>VP, Corporate Communications and Investor Relations<br \/>Tenaya Therapeutics<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=pe1HZFnBhk5TvJLG7OicAQUQekfT-gELQ33U-6SV9bHI140jHctP36ysegeh7KDVrhncxqj85fl9yFUo-Dt6_fjSwVFk97zCaIIrB5yn0I0=\" rel=\"nofollow\" target=\"_blank\">IR@TenayaThera.com<\/a><\/p>\n<p>\n        <strong>Investors<\/strong><br \/>\n        <br \/>AnneMarie Fields<br \/>Stern IR <br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=4xcLn5TMZbpz-yBhRYKUBZb7XH9tQlkfGHq_MXFBFck1kq9ZrQeV0oTi5lMYGdpYpPCjV55ZL5Hey0TBJ-lsQg6zp0MQHFOKIhRBOT0ezHcGxGMlqIi9aSuzSm_WAKF8\" rel=\"nofollow\" target=\"_blank\">AnneMarie.Fields@SternIR.com<\/a><\/p>\n<p>\n        <strong>Media<\/strong><br \/>\n        <br \/>Wendy Ryan<br \/>Ten\u00a0Bridge Communications<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=OFfPOtQFGbFB94Japts-wOCipWRMyC2q_14CgCLHwR8mSq9LwEcYNGESFkWC4c46yVtXqJiQ7eqX3i7vpjMye0Q_jrw_Z7iu1GaCOJoRIFLjf_DoplUlLDYgyTm3L2TwBak77eA2sobvF3UzqRHzZA==\" rel=\"nofollow\" target=\"_blank\">wendy@tenbridgecommunications.com<\/a><\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTM5Njc4OCM2ODEyNzY3IzIyMDk0NDY=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/OWExYTVmOWUtMWQ0MC00NzMxLWI1MjYtNzMyOTMxZmZiNzU0LTEyMjA5OTktMjAyNS0wMy0xOS1lbg==\/tiny\/Tenaya-Therapeutics-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Late Breaker Oral Presentation to Include New Data from Cohort 1 of the MyPEAK\u2122-1 Phase 1b\/2 Clinical Trial of TN-201 SOUTH SAN FRANCISCO, Calif., March 19, 2025 (GLOBE NEWSWIRE) &#8212; Tenaya Therapeutics, Inc. (NASDAQ: TNYA), a clinical-stage biotechnology company with a mission to discover, develop and deliver potentially curative therapies that address the underlying causes of heart disease, today announced that new clinical and disease burden data pertaining to the company\u2019s MYBPC3-associated hypertrophic cardiomyopathy (HCM) program will be presented at the upcoming American College of Cardiology\u2019s Annual Scientific Session being held March 29-31, 2025 in Chicago, IL. Tenaya is advancing TN-201, an AAV9-based gene therapy for the potential treatment of MYBPC3-associated HCM, a condition caused by insufficient levels of myosin-binding &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-827478","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Late Breaker Oral Presentation to Include New Data from Cohort 1 of the MyPEAK\u2122-1 Phase 1b\/2 Clinical Trial of TN-201 SOUTH SAN FRANCISCO, Calif., March 19, 2025 (GLOBE NEWSWIRE) &#8212; Tenaya Therapeutics, Inc. (NASDAQ: TNYA), a clinical-stage biotechnology company with a mission to discover, develop and deliver potentially curative therapies that address the underlying causes of heart disease, today announced that new clinical and disease burden data pertaining to the company\u2019s MYBPC3-associated hypertrophic cardiomyopathy (HCM) program will be presented at the upcoming American College of Cardiology\u2019s Annual Scientific Session being held March 29-31, 2025 in Chicago, IL. Tenaya is advancing TN-201, an AAV9-based gene therapy for the potential treatment of MYBPC3-associated HCM, a condition caused by insufficient levels of myosin-binding &hellip; Continue reading &quot;Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-03-19T12:34:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTM5Njc4OCM2ODEyNzY3IzIyMDk0NDY=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session\",\"datePublished\":\"2025-03-19T12:34:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\\\/\"},\"wordCount\":594,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTM5Njc4OCM2ODEyNzY3IzIyMDk0NDY=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\\\/\",\"name\":\"Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/","og_locale":"en_US","og_type":"article","og_title":"Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session - Market Newsdesk","og_description":"Late Breaker Oral Presentation to Include New Data from Cohort 1 of the MyPEAK\u2122-1 Phase 1b\/2 Clinical Trial of TN-201 SOUTH SAN FRANCISCO, Calif., March 19, 2025 (GLOBE NEWSWIRE) &#8212; Tenaya Therapeutics, Inc. (NASDAQ: TNYA), a clinical-stage biotechnology company with a mission to discover, develop and deliver potentially curative therapies that address the underlying causes of heart disease, today announced that new clinical and disease burden data pertaining to the company\u2019s MYBPC3-associated hypertrophic cardiomyopathy (HCM) program will be presented at the upcoming American College of Cardiology\u2019s Annual Scientific Session being held March 29-31, 2025 in Chicago, IL. Tenaya is advancing TN-201, an AAV9-based gene therapy for the potential treatment of MYBPC3-associated HCM, a condition caused by insufficient levels of myosin-binding &hellip; Continue reading \"Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/","og_site_name":"Market Newsdesk","article_published_time":"2025-03-19T12:34:00+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTM5Njc4OCM2ODEyNzY3IzIyMDk0NDY=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session","datePublished":"2025-03-19T12:34:00+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/"},"wordCount":594,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTM5Njc4OCM2ODEyNzY3IzIyMDk0NDY=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/tenaya-therapeutics-announces-late-breaker-and-new-data-presentations-at-the-american-college-of-cardiologys-annual-scientific-session\/","name":"Tenaya Therapeutics Announces Late Breaker and New Data Presentations at the American College of Cardiology\u2019s Annual Scientific Session - 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