{"id":822537,"date":"2025-03-06T08:18:04","date_gmt":"2025-03-06T13:18:04","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/"},"modified":"2025-03-06T08:18:04","modified_gmt":"2025-03-06T13:18:04","slug":"tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/","title":{"rendered":"Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwlistdecimal { list-style-type: decimal }\n.bwlistdisc { list-style-type: disc }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Tivic Health and Feinstein Institute Present New Data Showing <\/b><b>Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System<\/b><\/p>\n<p class=\"bwalignc\">\nAdvances Tivic\u2019s Development of Non-Invasive VNS Devices Aimed at Treating Inflammatory, Cardiac and Neurologic Disorders\n<\/p>\n<p>FREMONT, Calif.&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.tivichealth.com%2F&amp;esheet=54220167&amp;newsitemid=20250306669640&amp;lan=en-US&amp;anchor=Tivic+Health%26%23174%3B+Systems%2C+Inc.&amp;index=1&amp;md5=1966c6b12c49c9f0774d1e7cda697693\">Tivic Health<sup>\u00ae<\/sup> Systems, Inc.<\/a> (Nasdaq: TIVC), a diversified therapeutics company, announced today new data that shows personalizing its non-invasive vagus nerve stimulation (ncVNS) method optimized the stimulation\u2019s impact on autonomic nervous system activity. Tivic Health believes these findings strongly support its strategy to develop highly personalized neuromodulation devices that can better address inflammatory, cardiac and neurologic disorders compared to current, more invasive treatment options.\n<\/p>\n<p>\nThe data were presented in a poster presentation, titled, \u201c<i>Autonomic, Cardiac, and Neural Effects from Non-Invasive Cervical Vagus Nerve Stimulation,<\/i>\u201d at the Sixth Bioelectronic Medicine Summit, March 4 &amp; 5. The findings were based on Tivic\u2019s collaboration with The Feinstein Institute of Medicine, one of the global scientific leaders in bioelectronic medicine.\n<\/p>\n<p>\n\u201cThese promising findings reinforce Tivic\u2019s premise that non-invasive bioelectronic devices can effectively treat inflammatory, cardiac and neurologic disorders without invasive surgeries or pharmaceuticals &#8211; both of which carry burdensome side effects,\u201d said Jennifer Ernst, CEO of Tivic Health. \u201cWith these new data secured with pending patents, we believe that we have demonstrated the potential for developing personalized, scalable bioelectronic therapies to treat patients in need.\u201d\n<\/p>\n<p>\nTivic Health\u2019s poster presentation, titled, \u201c<i>Autonomic, Cardiac, and Neural Effects from Non-Invasive Cervical Vagus Nerve Stimulation,<\/i>\u201d highlighted a novel ncVNS approach and its ability to modulate autonomic nervous system (ANS) function and brain activity. Key results included:\n<\/p>\n<ol class=\"bwlistdecimal\">\n<li>\nPersonalized stimulation approach for optimal autonomic modulation:<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nNo single stimulation frequency had a universally dominant effect on HRV, highlighting the need for\u00a0personalized neuromodulation strategies.\n<\/li>\n<li>\nChoosing the optimal ncVNS stimulation frequency for each study subject resulted in a meaningful increase in effect size of HRV change, paving the way for patient-specific therapy.\n<\/li>\n<\/ul>\n<\/li>\n<li>\nSignificant increase in heart rate variability (HRV), indicating enhanced parasympathetic activity:<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nIn\u00a060% of participants (responders),\u00a0raw HRV nearly doubled\u00a0on average following ncVNS stimulation.\n<\/li>\n<li>\nNormalized HRV increased 2.67x post-stimulation, suggesting a strong activation of vagal tone and improved autonomic balance.\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<p>\nThe data presented resulted from Tivic\u2019s ongoing collaboration with the Feinstein Institute of Bioelectronic Medicine to advance high-precision vagus nerve stimulation in a non-invasive form factor.\n<\/p>\n<p><b>About The Bioelectronic Medicine (BEM) Summit<\/b><\/p>\n<p>\nThe BEM Summit is a premier gathering of industry leaders, researchers, and clinicians exploring cutting-edge neurotechnologies and neuromodulation therapies. Hosted by the Feinstein Institutes for Medical Research, the event brings together experts in bioelectronic medicine, autonomic neuroscience, and inflammation research to discuss the latest advancements in the field.\n<\/p>\n<p><b>About Tivic Health Systems, Inc.<\/b><\/p>\n<p>\nTivic Health is a diversified therapeutics company harnessing the power of the immune and autonomic nervous systems to fight disease and restore health. Tivic Health\u2019s bioelectronic division is developing non-invasive medical devices that personalize key stimulation parameters for the vagus nerve to deliver meaningfully improved effects on measures of the autonomous nervous system compared to current treatments, which are often invasive, ineffective or both. Tivic Health\u2019s biopharma division\u2019s lead product candidate is the TLR5 agonist,<strong \/>Entolimod\u2122, which is in late-stage studies to treat acute radiation syndrome. The FDA has granted<strong \/>Fast Track and Orphan Drug designation to Entolimod\u2122.\n<\/p>\n<p>\nTivic Health already has an FDA-approved over-the-counter device, ClearUP\u2122 that treats sinus pain and pressure and is available through online retailers and commercial distributors. For more information about Tivic Health, visit: <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fir.tivichealth.com&amp;esheet=54220167&amp;newsitemid=20250306669640&amp;lan=en-US&amp;anchor=https%3A%2F%2Fir.tivichealth.com&amp;index=2&amp;md5=4769bd8c4d2cc1453f53a2f012f1e50f\">https:\/\/ir.tivichealth.com<\/a><\/p>\n<p><b>Forward-Looking Statements<\/b><\/p>\n<p><i>This press release may contain \u201cforward-looking statements\u201d that are subject to substantial risks and<\/i><i>uncertainties. All statements, other than statements of historical fact, contained in this press release are<\/i><i>forward-looking statements. Forward-looking statements contained in this press release may be<\/i><i>identified by the use of words such as \u201canticipate,\u201d \u201cbelieve,\u201d \u201ccontemplate,\u201d \u201ccould,\u201d \u201cestimate,\u201d \u201cexpect,\u201d \u201cintend,\u201d \u201cseek,\u201d \u201cmay,\u201d \u201cmight,\u201d \u201cplan,\u201d \u201cpotential,\u201d \u201cpredict,\u201d \u201cproject,\u201d \u201ctarget,\u201d \u201caim,\u201d<\/i><i>\u201cshould,\u201d \u201cwill\u201d \u201cwould,\u201d or the negative of these words or other similar expressions, although not all<\/i><i>forward-looking statements contain these words. Forward-looking statements are based on Tivic Health<\/i><i>Systems, Inc.\u2019s current expectations and are subject to inherent uncertainties, risks, and assumptions<\/i><i>that are difficult to predict. Further, certain forward-looking statements are based on assumptions as to<\/i><i>future events that may not prove to be accurate, including as a result of changes to the company\u2019s relationship with the Feinstein Institute, future development of the company\u2019s ncVNS treatment, changes to the company\u2019s business strategy, clinical trial and study results, consummation of any strategic transactions, the company\u2019s need for, and ability to secure when needed, additional working capital, and the company\u2019s ability to maintain its Nasdaq listing. Actual results could differ materially from those contained in any forward-looking statement as a result of various factors. Accordingly, you are cautioned not to place undue reliance on such forward-looking statements. For a discussion of risks and uncertainties relevant to the company, and other important factors, see Tivic Health\u2019s filings with the SEC, including, its Annual Report on Form 10-K for the year ended December 31, 2023, filed with the SEC on March 29, 2024, under the heading \u201cRisk Factors\u201d; as well as the company\u2019s subsequent filings with the SEC. Forward-looking statements contained in this press release are made as of this date, and Tivic Health Systems, Inc. undertakes no duty to update such information except as required by applicable law.<\/i><\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20250306669640r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20250306669640\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20250306669640\/en\/<\/a><\/span><\/p>\n<p><b>Investor Contact:<br \/>\n<\/b><br \/>Hanover International, Inc.<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:ir@tivichealth.com\">ir@tivichealth.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> United States North America California<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Biotechnology Neurology Health Science Research<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20250306669640\/en\/1936575\/3\/Tivic_logo.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System Advances Tivic\u2019s Development of Non-Invasive VNS Devices Aimed at Treating Inflammatory, Cardiac and Neurologic Disorders FREMONT, Calif.&#8211;(BUSINESS WIRE)&#8211;Tivic Health\u00ae Systems, Inc. (Nasdaq: TIVC), a diversified therapeutics company, announced today new data that shows personalizing its non-invasive vagus nerve stimulation (ncVNS) method optimized the stimulation\u2019s impact on autonomic nervous system activity. Tivic Health believes these findings strongly support its strategy to develop highly personalized neuromodulation devices that can better address inflammatory, cardiac and neurologic disorders compared to current, more invasive treatment options. The data were presented in a poster presentation, titled, \u201cAutonomic, Cardiac, and Neural Effects from Non-Invasive Cervical Vagus Nerve &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-822537","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System Advances Tivic\u2019s Development of Non-Invasive VNS Devices Aimed at Treating Inflammatory, Cardiac and Neurologic Disorders FREMONT, Calif.&#8211;(BUSINESS WIRE)&#8211;Tivic Health\u00ae Systems, Inc. (Nasdaq: TIVC), a diversified therapeutics company, announced today new data that shows personalizing its non-invasive vagus nerve stimulation (ncVNS) method optimized the stimulation\u2019s impact on autonomic nervous system activity. Tivic Health believes these findings strongly support its strategy to develop highly personalized neuromodulation devices that can better address inflammatory, cardiac and neurologic disorders compared to current, more invasive treatment options. The data were presented in a poster presentation, titled, \u201cAutonomic, Cardiac, and Neural Effects from Non-Invasive Cervical Vagus Nerve &hellip; Continue reading &quot;Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-03-06T13:18:04+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20250306669640r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System\",\"datePublished\":\"2025-03-06T13:18:04+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\\\/\"},\"wordCount\":945,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20250306669640r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\\\/\",\"name\":\"Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System - 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(Nasdaq: TIVC), a diversified therapeutics company, announced today new data that shows personalizing its non-invasive vagus nerve stimulation (ncVNS) method optimized the stimulation\u2019s impact on autonomic nervous system activity. Tivic Health believes these findings strongly support its strategy to develop highly personalized neuromodulation devices that can better address inflammatory, cardiac and neurologic disorders compared to current, more invasive treatment options. The data were presented in a poster presentation, titled, \u201cAutonomic, Cardiac, and Neural Effects from Non-Invasive Cervical Vagus Nerve &hellip; Continue reading \"Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/","og_site_name":"Market Newsdesk","article_published_time":"2025-03-06T13:18:04+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20250306669640r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System","datePublished":"2025-03-06T13:18:04+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/"},"wordCount":945,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20250306669640r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/tivic-health-and-feinstein-institute-present-new-data-showing-personalized-vagus-nerve-stimulation-method-optimizes-impact-on-autonomic-nervous-system\/","name":"Tivic Health and Feinstein Institute Present New Data Showing Personalized Vagus Nerve Stimulation Method Optimizes Impact on Autonomic Nervous System - 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