{"id":821122,"date":"2025-03-04T07:08:37","date_gmt":"2025-03-04T12:08:37","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki-crrt-conference\/"},"modified":"2025-03-04T07:08:37","modified_gmt":"2025-03-04T12:08:37","slug":"calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki-crrt-conference","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki-crrt-conference\/","title":{"rendered":"CalciMedica Presents AKI Data from a Post-Hoc Analysis of the Phase 2 CARDEA trial of Auxora\u2122 in Severe COVID-19 Pneumonia at the 30th International AKI &amp; CRRT Conference"},"content":{"rendered":"<div class=\"xn-newslines\">\n<p class=\"xn-distributor\">PR Newswire<\/p>\n<\/p><\/div>\n<div class=\"xn-content\">\n<p class=\"prntac\">\n        <i>62.7% relative reduction in mortality at day 30, which persisted through day 60, for patients treated with Auxora versus placebo in subset of patients in CARDEA with AKI<\/i>\n      <\/p>\n<p>\n        <span class=\"legendSpanClass\"><br \/>\n          <span class=\"xn-location\">LA JOLLA, Calif.<\/span><br \/>\n        <\/span>, <span class=\"legendSpanClass\"><span class=\"xn-chron\">March 4, 2025<\/span><\/span> \/PRNewswire\/ &#8212; CalciMedica Inc. (&#8220;CalciMedica&#8221; or the &#8220;Company&#8221;) (Nasdaq: CALC), a clinical-stage biopharmaceutical company focused on developing novel calcium release-activated calcium (CRAC) channel inhibition therapies for acute and chronic inflammatory and immunologic illnesses, today announced\u00a0that <span class=\"xn-person\">Sudarshan Hebbar<\/span>, M.D., Chief Medical Officer of CalciMedica, delivered a plenary presentation at the 30<sup>th<\/sup> International Acute Kidney Injury and Continuous Renal Replacement Therapy Conference (AKI &amp; CRRT) on <span class=\"xn-chron\">March 3, 2025<\/span> in <span class=\"xn-location\">San Diego, CA.<\/span> The presentation outlined the role of CRAC channels in acute kidney injury (AKI) pathophysiology and included new data highlighting the potential of CalciMedica&#8217;s lead product candidate, Auxora\u2122, in AKI. CalciMedica is currently conducting a Phase 2 trial of Auxora in patients with Stage 2 or Stage 3 AKI and acute hypoxemic respiratory failure, which is expected to read out in 2025.<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<p>\n          <a href=\"https:\/\/mma.prnewswire.com\/media\/685404\/calcimedica_v3.html\" target=\"_blank\" rel=\"nofollow\"><br \/>\n            <img decoding=\"async\" src=\"https:\/\/mma.prnewswire.com\/media\/685404\/calcimedica_v3.jpg\" title=\"CalciMedica Logo (PRNewsfoto\/CalciMedica, Inc.)\" alt=\"CalciMedica Logo (PRNewsfoto\/CalciMedica, Inc.)\" \/><br \/>\n          <\/a>\n        <\/p>\n<\/p><\/div>\n<p>The new data presented were based on a post-hoc analysis from the previously completed Phase 2 CARDEA trial of Auxora in severe COVID-19 pneumonia. The study included 38 patients who enrolled with AKI, defined as an estimated glomerular filtration rate (eGFR) \u2264 60 ml\/min\/1.73 m\u00b2, in addition to moderate or severe respiratory failure, which was an inclusion criterion. Within this subset:<\/p>\n<ul type=\"disc\">\n<li>Patients treated with Auxora showed a 62.7% relative reduction versus placebo in mortality at day 30 which persisted through day 60.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<ul type=\"circle\">\n<li>7 out of 15 (46.7%) patients on placebo died by day 30 and day 60 as compared to 4 out of 23 (17.4%) patients on Auxora.<\/li>\n<li>Auxora exhibited an absolute reduction in mortality of 29.3%.<\/li>\n<\/ul>\n<\/ul>\n<p>This reduction in mortality in the patient subset with AKI exceeded that of the entire study population. In the entire population (n = 261), a 56.3% (p = 0.017) relative reduction versus placebo in mortality at day 30 was observed, with an absolute reduction of 9.9% versus placebo.<\/p>\n<p>In his presentation, Dr. Hebbar also summarized previously disclosed data supporting the role of CRAC channel inhibition as a potential therapeutic mechanism in AKI. Key data include:<\/p>\n<ul type=\"disc\">\n<li>In preclinical biomarker studies, rats with AKI following ischemic reperfusion injury had decreased Th17 cells in their kidneys when receiving a CRAC inhibitor versus control, highlighting immunomodulatory effects.\n<\/li>\n<li>In in-vitro experiments, CRAC channel inhibition ameliorated injury to podocyte cells (kidney cells involved in filtration) caused by high glucose or angiotensin II, highlighting tissue-protective effects.\n<\/li>\n<li>In preclinical outcome studies, GFRs recovered more quickly and mortality was reduced in rats with severe or moderately severe AKI that received Auxora versus placebo.\n<\/li>\n<li>In clinical trial biomarker studies, CARDEA patients who received Auxora versus placebo had changes in cardiorenal biomarkers\u2014increases in angiopoietin-1 and decreases in angiopoietin-2 and D-dimers\u2014which have been linked to the prevention of endothelial damage in prior studies and were correlated with improved outcomes in CARDEA.\n<\/li>\n<li>At doses used experimentally and clinically, Auxora potentially provides a therapeutic window to treat acute critical illnesses without increasing risk of infection.<\/li>\n<\/ul>\n<p>&#8220;As illustrated by these data, the biological rationale for CRAC channel inhibition as a potential therapeutic mechanism for AKI is compelling,&#8221; said <span class=\"xn-person\">Sudarshan Hebbar<\/span>, M.D., Chief Medical Officer of CalciMedica. &#8220;The post-hoc analysis from CARDEA is especially relevant given that the 62.7% relative reduction in mortality was observed in patients with both kidney failure and respiratory failure, which mirrors the intended patient population for our ongoing Phase 2 KOURAGE study.&#8221;<\/p>\n<p>The presentation is now available on the Medical Events &amp; Presentations section of CalciMedica&#8217;s IR website at <a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=4374570-1&amp;h=2608611678&amp;u=https%3A%2F%2Fir.calcimedica.com%2Fnews-events%2Fmedical-events-publications&amp;a=https%3A%2F%2Fir.calcimedica.com%2Fnews-events%2Fmedical-events-publications\" target=\"_blank\" rel=\"nofollow\">https:\/\/ir.calcimedica.com\/news-events\/medical-events-publications<\/a>.<\/p>\n<p>\n        <b>About CalciMedica<br \/><\/b>CalciMedica\u00a0is a clinical-stage biopharmaceutical company focused on developing novel CRAC channel inhibition therapies for inflammatory and immunologic diseases.\u00a0CalciMedica&#8217;s\u00a0proprietary technology targets the inhibition of CRAC channels to modulate the immune response and protect against tissue cell injury, with the potential to provide therapeutic benefits in life-threatening inflammatory and immunologic diseases for which there are currently no approved therapies.\u00a0CalciMedica&#8217;s\u00a0lead product candidate\u00a0Auxora\u2122 has demonstrated positive and consistent clinical results in multiple completed efficacy clinical trials. CalciMedica\u00a0has announced data for a Phase <span class=\"xn-money\">2b<\/span> trial (called CARPO \u2013\u00a0<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=4374570-1&amp;h=3600201267&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4354022-1%26h%3D507515521%26u%3Dhttps%253A%252F%252Fc212.net%252Fc%252Flink%252F%253Ft%253D0%2526l%253Den%2526o%253D4339678-1%2526h%253D2357721873%2526u%253Dhttps%25253A%25252F%25252Fc212.net%25252Fc%25252Flink%25252F%25253Ft%25253D0%252526l%25253Den%252526o%25253D4243427-1%252526h%25253D2669185696%252526u%25253Dhttps%2525253A%2525252F%2525252Fc212.net%2525252Fc%2525252Flink%2525252F%2525253Ft%2525253D0%25252526l%2525253Den%25252526o%2525253D4231092-1%25252526h%2525253D1699697110%25252526u%2525253Dhttps%252525253A%252525252F%252525252Fclinicaltrials.gov%252525252Fstudy%252525252FNCT04681066%252525253Fterm%252525253DNCT04681066%2525252526rank%252525253D1%25252526a%2525253DNCT04681066%252526a%25253DNCT04681066%2526a%253DNCT04681066%26a%3DNCT04681066&amp;a=NCT04681066\" target=\"_blank\" rel=\"nofollow\">NCT04681066<\/a>) in patients with acute pancreatitis (AP) and accompanying systemic inflammatory response syndrome (SIRS). The Company has also completed a Phase 2 trial (called CARDEA \u2013\u00a0<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=4374570-1&amp;h=687292991&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4354022-1%26h%3D1581608759%26u%3Dhttps%253A%252F%252Fc212.net%252Fc%252Flink%252F%253Ft%253D0%2526l%253Den%2526o%253D4339678-1%2526h%253D2705666193%2526u%253Dhttps%25253A%25252F%25252Fc212.net%25252Fc%25252Flink%25252F%25253Ft%25253D0%252526l%25253Den%252526o%25253D4243427-1%252526h%25253D3152801644%252526u%25253Dhttps%2525253A%2525252F%2525252Fc212.net%2525252Fc%2525252Flink%2525252F%2525253Ft%2525253D0%25252526l%2525253Den%25252526o%2525253D4231092-1%25252526h%2525253D1827566996%25252526u%2525253Dhttps%252525253A%252525252F%252525252Fc212.net%252525252Fc%252525252Flink%252525252F%252525253Ft%252525253D0%2525252526l%252525253Den%2525252526o%252525253D4206849-1%2525252526h%252525253D575802973%2525252526u%252525253Dhttps%25252525253A%25252525252F%25252525252Fclinicaltrials.gov%25252525252Fstudy%25252525252FNCT04345614%2525252526a%252525253DNCT04345614%25252526a%2525253DNCT04345614%252526a%25253DNCT04345614%2526a%253DNCT04345614%26a%3DNCT04345614&amp;a=NCT04345614\" target=\"_blank\" rel=\"nofollow\">NCT04345614<\/a>) in patients with COVID pneumonia. The Company is currently conducting a Phase 2 trial (called KOURAGE \u2013\u00a0<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=4374570-1&amp;h=2262471863&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4354022-1%26h%3D1219378198%26u%3Dhttps%253A%252F%252Fc212.net%252Fc%252Flink%252F%253Ft%253D0%2526l%253Den%2526o%253D4339678-1%2526h%253D3911003323%2526u%253Dhttps%25253A%25252F%25252Fc212.net%25252Fc%25252Flink%25252F%25253Ft%25253D0%252526l%25253Den%252526o%25253D4243427-1%252526h%25253D2144183414%252526u%25253Dhttps%2525253A%2525252F%2525252Fc212.net%2525252Fc%2525252Flink%2525252F%2525253Ft%2525253D0%25252526l%2525253Den%25252526o%2525253D4231092-1%25252526h%2525253D78069076%25252526u%2525253Dhttps%252525253A%252525252F%252525252Fclinicaltrials.gov%252525252Fstudy%252525252FNCT06374797%252525253Fterm%252525253DKOURAGE%2525252526rank%252525253D1%25252526a%2525253DNCT06374797%252526a%25253DNCT06374797%2526a%253DNCT06374797%26a%3DNCT06374797&amp;a=NCT06374797\" target=\"_blank\" rel=\"nofollow\">NCT06374797<\/a>) in patients with acute kidney injury (AKI) with associated acute hypoxemic respiratory failure (AHRF) with data expected in 2025 and continuing to support the ongoing Phase 1\/2 trial (called CRSPA \u2013\u00a0<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=4374570-1&amp;h=3509584099&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4354022-1%26h%3D3221819043%26u%3Dhttps%253A%252F%252Fc212.net%252Fc%252Flink%252F%253Ft%253D0%2526l%253Den%2526o%253D4339678-1%2526h%253D3395865876%2526u%253Dhttps%25253A%25252F%25252Fc212.net%25252Fc%25252Flink%25252F%25253Ft%25253D0%252526l%25253Den%252526o%25253D4243427-1%252526h%25253D1916833438%252526u%25253Dhttps%2525253A%2525252F%2525252Fc212.net%2525252Fc%2525252Flink%2525252F%2525253Ft%2525253D0%25252526l%2525253Den%25252526o%2525253D4231092-1%25252526h%2525253D2087960553%25252526u%2525253Dhttps%252525253A%252525252F%252525252Fc212.net%252525252Fc%252525252Flink%252525252F%252525253Ft%252525253D0%2525252526l%252525253Den%2525252526o%252525253D4206849-1%2525252526h%252525253D3497808046%2525252526u%252525253Dhttps%25252525253A%25252525252F%25252525252Fclinicaltrials.gov%25252525252Fstudy%25252525252FNCT04195347%25252525253Fterm%25252525253DNCT04195347%252525252526rank%25252525253D1%2525252526a%252525253DNCT04195347%25252526a%2525253DNCT04195347%252526a%25253DNCT04195347%2526a%253DNCT04195347%26a%3DNCT04195347&amp;a=NCT04195347\" target=\"_blank\" rel=\"nofollow\">NCT04195347<\/a>) in pediatric patients with asparaginase-induced pancreatic toxicity (AIPT) with data expected in 2025.\u00a0CalciMedica\u00a0was founded by scientists from Torrey Pines Therapeutics and the\u00a0Harvard CBR Institute for Biomedical Research, and is headquartered in\u00a0La Jolla, CA.\u00a0For more information, please visit\u00a0<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=4374570-1&amp;h=344873490&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4354022-1%26h%3D1665326854%26u%3Dhttps%253A%252F%252Fcalcimedica.com%252F%26a%3Dwww.calcimedica.com&amp;a=www.calcimedica.com\" target=\"_blank\" rel=\"nofollow\">www.calcimedica.com<\/a>.<\/p>\n<p>\n        <b>Forward-Looking Statements<br \/><\/b>This communication contains forward-looking statements which include, but are not limited to, results of post-hoc analyses from the previously completed Phase 2 CARDEA trial of Auxora and\u00a0\u00a0CalciMedica&#8217;s\u00a0ongoing and planned clinical trials and the timing and design thereof, and the expected timing for the release of data from those trials, including its ongoing Phase 1\/2 CRSPA trial of Auxora in pediatric patients with AIPT and its ongoing Phase 2 KOURAGE trial of Auxora in AKI with associated AHRF; the potential benefits of Auxora for the treatment of AP, AKI and AIPT; and the potential of\u00a0CalciMedica&#8217;s\u00a0proprietary technology to provide therapeutic benefits in life-threatening inflammatory and immunologic diseases. These forward-looking statements are subject to the safe harbor provisions under the Private Securities Litigation Reform Act of 1995.\u00a0CalciMedica&#8217;s\u00a0expectations and beliefs regarding these matters may not materialize. Actual outcomes and results may differ materially from those contemplated by these forward-looking statements as a result of uncertainties, risks, and changes in circumstances. Risks and uncertainties that could cause actual outcomes and results to differ materially from those contemplated by the forward-looking statements are included under the caption &#8220;Risk Factors&#8221; in\u00a0CalciMedica&#8217;s\u00a0Quarterly Report on Form 10-Q for the quarter ended\u00a0September 30, 2024, filed with the\u00a0U.S. Securities and Exchange Commission\u00a0(SEC) on\u00a0November 13, 2024, and elsewhere in\u00a0CalciMedica&#8217;s\u00a0subsequent reports on Form 10-K, Form 10-Q or Form 8-K filed with the\u00a0SEC\u00a0from time to time and available at\u00a0<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=4374570-1&amp;h=1755358833&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4339678-1%26h%3D2349260596%26u%3Dhttps%253A%252F%252Fwww.sec.gov%252F%26a%3Dwww.sec.gov&amp;a=www.sec.gov\" target=\"_blank\" rel=\"nofollow\">www.sec.gov<\/a>. These documents can be accessed on\u00a0CalciMedica&#8217;s\u00a0web page at\u00a0<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=4374570-1&amp;h=3844639872&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D4339678-1%26h%3D859834820%26u%3Dhttps%253A%252F%252Fir.calcimedica.com%252Ffinancials-filings%252Fsec-filings%26a%3Dir.calcimedica.com%252Ffinancials-filings%252Fsec-filings&amp;a=ir.calcimedica.com%2Ffinancials-filings%2Fsec-filings\" target=\"_blank\" rel=\"nofollow\">ir.calcimedica.com\/financials-filings\/sec-filings<\/a>. The forward-looking statements contained herein are made as of the date hereof, and\u00a0CalciMedica\u00a0undertakes no obligation to update them after this date, except as required by law.<\/p>\n<p>\n        <b>Contact Information<br \/><\/b>Argot Partners<br \/><span class=\"xn-person\">Sarah Sutton<\/span>\/<span class=\"xn-person\">Kevin Murphy<\/span><br \/><a href=\"mailto:calcimedica@argotpartners.com\" target=\"_blank\" rel=\"nofollow\">calcimedica@argotpartners.com<\/a><br \/>(212) 600-1902<\/p>\n<p id=\"PURL\">\n        <img loading=\"lazy\" decoding=\"async\" title=\"Cision\" width=\"12\" height=\"12\" alt=\"Cision\" src=\"https:\/\/c212.net\/c\/img\/favicon.png?sn=LA31976&amp;sd=2025-03-04\" \/> View original content to download multimedia:<a id=\"PRNURL\" rel=\"nofollow\" href=\"https:\/\/www.prnewswire.com\/news-releases\/calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki--crrt-conference-302390747.html\" target=\"_blank\">https:\/\/www.prnewswire.com\/news-releases\/calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki&#8211;crrt-conference-302390747.html<\/a><\/p>\n<p>SOURCE  CalciMedica, Inc.<\/p>\n<\/p><\/div>\n<p>    <img decoding=\"async\" alt=\"\" src=\"https:\/\/rt.prnewswire.com\/rt.gif?NewsItemId=LA31976&amp;Transmission_Id=202503040700PR_NEWS_USPR_____LA31976&amp;DateId=20250304\" style=\"border:0px;width:1px;height:1px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>PR Newswire 62.7% relative reduction in mortality at day 30, which persisted through day 60, for patients treated with Auxora versus placebo in subset of patients in CARDEA with AKI LA JOLLA, Calif. , March 4, 2025 \/PRNewswire\/ &#8212; CalciMedica Inc. (&#8220;CalciMedica&#8221; or the &#8220;Company&#8221;) (Nasdaq: CALC), a clinical-stage biopharmaceutical company focused on developing novel calcium release-activated calcium (CRAC) channel inhibition therapies for acute and chronic inflammatory and immunologic illnesses, today announced\u00a0that Sudarshan Hebbar, M.D., Chief Medical Officer of CalciMedica, delivered a plenary presentation at the 30th International Acute Kidney Injury and Continuous Renal Replacement Therapy Conference (AKI &amp; CRRT) on March 3, 2025 in San Diego, CA. The presentation outlined the role of CRAC channels in acute kidney injury &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki-crrt-conference\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;CalciMedica Presents AKI Data from a Post-Hoc Analysis of the Phase 2 CARDEA trial of Auxora\u2122 in Severe COVID-19 Pneumonia at the 30th International AKI &amp; CRRT Conference&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-821122","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>CalciMedica Presents AKI Data from a Post-Hoc Analysis of the Phase 2 CARDEA trial of Auxora\u2122 in Severe COVID-19 Pneumonia at the 30th International AKI &amp; CRRT Conference - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki-crrt-conference\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CalciMedica Presents AKI Data from a Post-Hoc Analysis of the Phase 2 CARDEA trial of Auxora\u2122 in Severe COVID-19 Pneumonia at the 30th International AKI &amp; CRRT Conference - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"PR Newswire 62.7% relative reduction in mortality at day 30, which persisted through day 60, for patients treated with Auxora versus placebo in subset of patients in CARDEA with AKI LA JOLLA, Calif. , March 4, 2025 \/PRNewswire\/ &#8212; CalciMedica Inc. (&#8220;CalciMedica&#8221; or the &#8220;Company&#8221;) (Nasdaq: CALC), a clinical-stage biopharmaceutical company focused on developing novel calcium release-activated calcium (CRAC) channel inhibition therapies for acute and chronic inflammatory and immunologic illnesses, today announced\u00a0that Sudarshan Hebbar, M.D., Chief Medical Officer of CalciMedica, delivered a plenary presentation at the 30th International Acute Kidney Injury and Continuous Renal Replacement Therapy Conference (AKI &amp; CRRT) on March 3, 2025 in San Diego, CA. The presentation outlined the role of CRAC channels in acute kidney injury &hellip; Continue reading &quot;CalciMedica Presents AKI Data from a Post-Hoc Analysis of the Phase 2 CARDEA trial of Auxora\u2122 in Severe COVID-19 Pneumonia at the 30th International AKI &amp; CRRT Conference&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki-crrt-conference\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-03-04T12:08:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mma.prnewswire.com\/media\/685404\/calcimedica_v3.jpg\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki-crrt-conference\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/calcimedica-presents-aki-data-from-a-post-hoc-analysis-of-the-phase-2-cardea-trial-of-auxora-in-severe-covid-19-pneumonia-at-the-30th-international-aki-crrt-conference\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"CalciMedica Presents AKI Data from a Post-Hoc Analysis of the Phase 2 CARDEA trial of Auxora\u2122 in Severe COVID-19 Pneumonia at the 30th International AKI &amp; 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