{"id":813009,"date":"2025-02-13T16:08:51","date_gmt":"2025-02-13T21:08:51","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/virpax-confirms-positive-results-with-us-army-with-probudur-for-combat-care-study\/"},"modified":"2025-02-13T16:08:51","modified_gmt":"2025-02-13T21:08:51","slug":"virpax-confirms-positive-results-with-us-army-with-probudur-for-combat-care-study","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/virpax-confirms-positive-results-with-us-army-with-probudur-for-combat-care-study\/","title":{"rendered":"Virpax Confirms Positive Results with US Army with Probudur\u2122 for Combat Care Study"},"content":{"rendered":"

<\/p>\n

Virpax Confirms Positive Results with US Army with Probudur<\/b>\u2122<\/b><\/sup> for Combat Care Study<\/b><\/p>\n

BERWYN, Pa.–(BUSINESS WIRE<\/a>)–Virpax Pharmaceuticals, Inc. (Nasdaq: VRPX) (\u201cVirpax\u201d or the \u201cCompany\u201d)<\/b>, a company specializing in developing non-addictive products for pain management, post-traumatic stress disorder, central nervous system (CNS) disorders and anti-viral barrier indications, today announced the completion of the full study that followed the initial Probudur\u2122 pilot study performed by the U.S. Army Institute of Surgical Research (USAISR) under an existing Cooperative Research and Development Agreement (CRADA).<\/p>\n

\nThe USAISR is the U.S. Department of Defense\u2019s premier research organization for developing solutions for trauma and critical care challenges in combat casualties. This study was designed to determine if Probudur reduces pain behaviors in a rat model of incisional pain. The surgical procedures and assessments were identical to those in the pilot study. The study compared Probudur with free bupivacaine and EXPAREL\u00ae.<\/p>\n

\nVarious concentrations of Probudur were injected into the tissue around the incision site as well as a saline solution for the control group. The doses of Probudur showed reduction in incision-induced pain behaviors. \u201cThese positive results are consistent with what we at Virpax have previously observed and we are encouraged by these findings,\u201d commented Jatinder Dhaliwal, Chief Executive Officer of Virpax.<\/p>\n

\nProbudur is being developed to achieve the overall goal of safe and effective pain control during the perioperative period and to significantly reduce or eliminate the need for opioids after surgery in approved indications. Probudur is a local anesthetic that binds to the sodium channels, preventing pain signals from reaching the brain. In preclinical studies, Probudur has shown long duration pain control for at least 96 hours, with a rat incisional model demonstrating analgesia for up to five days and in vitro studies demonstrating a slow release of bupivacaine that lasted for up to six (6) days.<\/p>\n

About Virpax Pharmaceuticals, Inc.
\n
<\/b>Virpax is developing branded, non-addictive pain management products candidates using its proprietary technologies to optimize and target drug delivery. Virpax is initially seeking the U.S. Food and Drug Administration (FDA) approval for two prescription drug candidates that employ two different patented drug delivery platforms. Probudur\u2122 is a single injection liposomal bupivacaine formulation being developed to manage post-operative pain and Envelta\u2122 is an intranasal molecular envelope enkephalin formulation being developed to manage acute and chronic pain, including pain associated with cancer. Virpax is also using its intranasal Molecular Envelope Technology (MET) to develop one other prescription product candidate, NobrXiol\u2122, which is being developed for the nasal delivery of a pharmaceutical-grade cannabidiol (CBD) for the management of rare pediatric epilepsy. Virpax has competitive cooperative research and development agreements (CRADAs) for two of its prescription drug candidates, one with the National Institutes of Health (NIH) and one with the Department of Defense (DOD). Virpax is also seeking partners for two nonprescription product candidates: AnQlar, which is being developed to inhibit viral replication caused by influenza or SARS-CoV-2, and Epoladerm\u2122, which is a topical diclofenac spray film formulation being developed to manage pain associated with osteoarthritis. For more information, please visit https:\/\/www.virpaxpharma.com<\/a>.and follow us on Twitter, LinkedIn and YouTube.<\/p>\n

Forward-Looking Statements<\/i><\/b><\/p>\n

This press release contains certain forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995, as amended, including those described below. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management\u2019s current beliefs and assumptions.<\/i><\/p>\n

These statements may be identified by the use of forward-looking expressions, including, but not limited to, \u201cexpect,\u201d \u201canticipate,\u201d \u201cintend,\u201d \u201cplan,\u201d \u201cbelieve,\u201d \u201cestimate,\u201d \u201cpotential,\u201d \u201cpredict,\u201d \u201cproject,\u201d \u201cshould,\u201d \u201cwould\u201d and similar expressions and the negatives of those terms. These statements relate to future events and involve known and unknown risks, uncertainties, and other factors, including the additional capital which will be necessary to complete studies and clinical trials that the Company plans to initiate and other factors listed under \u201cRisk Factors\u201d in the Company\u2019s Annual Report on Form 10-K and Quarterly Reports on Form 10-Q that the Company has filed with the U.S. Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.<\/i><\/p>\n

\"\"<\/p>\n

View source version on businesswire.com: <\/span>https:\/\/www.businesswire.com\/news\/home\/20250213717392\/en\/<\/a><\/span><\/p>\n

Investor:
\n<\/b>
info@virpaxpharma.com<\/a><\/p>\n

KEYWORDS:<\/b> United States North America Pennsylvania<\/p>\n

INDUSTRY KEYWORDS:<\/b> FDA Health Surgery Clinical Trials General Health Pharmaceutical<\/p>\n

MEDIA:<\/b><\/p>\n\n","protected":false},"excerpt":{"rendered":"

Virpax Confirms Positive Results with US Army with Probudur\u2122 for Combat Care Study BERWYN, Pa.–(BUSINESS WIRE)–Virpax Pharmaceuticals, Inc. (Nasdaq: VRPX) (\u201cVirpax\u201d or the \u201cCompany\u201d), a company specializing in developing non-addictive products for pain management, post-traumatic stress disorder, central nervous system (CNS) disorders and anti-viral barrier indications, today announced the completion of the full study that followed the initial Probudur\u2122 pilot study performed by the U.S. Army Institute of Surgical Research (USAISR) under an existing Cooperative Research and Development Agreement (CRADA). The USAISR is the U.S. Department of Defense\u2019s premier research organization for developing solutions for trauma and critical care challenges in combat casualties. This study was designed to determine if Probudur reduces pain behaviors in a rat model of incisional … <\/p>\n

Continue reading “Virpax Confirms Positive Results with US Army with Probudur\u2122 for Combat Care Study”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-813009","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nVirpax Confirms Positive Results with US Army with Probudur\u2122 for Combat Care Study - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/virpax-confirms-positive-results-with-us-army-with-probudur-for-combat-care-study\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Virpax Confirms Positive Results with US Army with Probudur\u2122 for Combat Care Study - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Virpax Confirms Positive Results with US Army with Probudur\u2122 for Combat Care Study BERWYN, Pa.–(BUSINESS WIRE)–Virpax Pharmaceuticals, Inc. (Nasdaq: VRPX) (\u201cVirpax\u201d or the \u201cCompany\u201d), a company specializing in developing non-addictive products for pain management, post-traumatic stress disorder, central nervous system (CNS) disorders and anti-viral barrier indications, today announced the completion of the full study that followed the initial Probudur\u2122 pilot study performed by the U.S. Army Institute of Surgical Research (USAISR) under an existing Cooperative Research and Development Agreement (CRADA). The USAISR is the U.S. Department of Defense\u2019s premier research organization for developing solutions for trauma and critical care challenges in combat casualties. 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