{"id":802500,"date":"2025-01-21T07:07:14","date_gmt":"2025-01-21T12:07:14","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-announces-a-g-rex-grant-has-been-awarded-to-brainchild-bio\/"},"modified":"2025-01-21T07:07:14","modified_gmt":"2025-01-21T12:07:14","slug":"scaleready-announces-a-g-rex-grant-has-been-awarded-to-brainchild-bio","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-announces-a-g-rex-grant-has-been-awarded-to-brainchild-bio\/","title":{"rendered":"ScaleReady Announces a G-Rex\u00ae Grant has been awarded to BrainChild Bio"},"content":{"rendered":"<div class=\"xn-newslines\">\n<p class=\"xn-distributor\">PR Newswire<\/p>\n<\/p><\/div>\n<div class=\"xn-content\">\n<p>\n        <span class=\"legendSpanClass\"><br \/>\n          <span class=\"xn-location\">ST. PAUL, Minn.<\/span><br \/>\n        <\/span>, <span class=\"legendSpanClass\"><span class=\"xn-chron\">Jan. 21, 2025<\/span><\/span> \/PRNewswire\/ &#8212; ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation and CellReady, today announced that BrainChild Bio has been awarded a <span class=\"xn-money\">$300,000<\/span> G-Rex\u00ae Grant. The G-Rex\u00ae Grant will support expeditious process development and commercial readiness of BCB-276, BrainChild Bio&#8217;s lead autologous CAR-T therapy for the treatment of diffuse intrinsic pontine glioma (DIPG), an incurable type of pediatric brain tumor. BrainChild Bio plans to advance BCB-276 into a multi-center Phase 2 pivotal clinical trial in 2025 for the treatment of children and young adults with DIPG.<\/p>\n<p>&#8220;G-Rex has been an essential element of our clinical CAR-T manufacturing program at Seattle Children&#8217;s dating back to 2012. We greatly appreciate the support of ScaleReady&#8217;s G-Rex Grant Program as well as the technical expertise offered to us by ScaleReady related to new advancements,&#8221; said Dr. <span class=\"xn-person\">Michael Jensen<\/span>, Chief Scientific Officer at BrainChild Bio.<\/p>\n<p>&#8220;We have a tremendous amount of respect for pioneering CAR-T therapies that Dr. Jensen and his team have advanced over the last 15 years. Their relentless pursuit of cancer cures is inspiring. It&#8217;s an honor for our team to be able to help accelerate BrainChild&#8217;s novel BCB-276 treatment for brain tumors to those in need and this program is perfectly aligned with our goal of bringing hope to cancer patients,&#8221; said <span class=\"xn-person\">John Wilson<\/span>, CEO of Wilson Wolf Manufacturing Corporation and co-inventor of G-Rex.<\/p>\n<p>As part of the G-Rex Grant, BrainChild\u00a0Bio will perform process development and optimization of their G-Rex based CAR-T cell manufacturing process in anticipation of a pivotal clinical trial. Through this G-Rex Grant, ScaleReady will help BrainChild quickly establish optimal process simplicity, consistency, and flexibility in their manufacturing approach for BCB-276. Additionally, BrainChild\u00a0Bio will have the option to evaluate CellReady&#8217;s standardized CAR-T cell process, a highly efficient 7-day manufacturing process. The CellReady CAR-T process is a fully closed end-to-end process that incorporates the use of closed system G-Rex bioreactors and Bio-Techne&#8217;s new closed system ProPak GMP cytokines in a manufacturing workflow capable of delivering high-throughput products to patients.<\/p>\n<p>ScaleReady&#8217;s G-Rex Grant Program is a <span class=\"xn-money\">$20M<\/span> initiative to advance the state of cell and gene-modified cell therapy (CGT) development and manufacturing by awarding individual Grant Awards worth up to <span class=\"xn-money\">$300,000<\/span>. G-Rex Grant Recipients also gain access to exclusive support from ScaleReady&#8217;s growing consortium of G-Rex Grant Partners who bring best-in-class tools and technologies as well as unparalleled knowledge and expertise in the areas of cGMP manufacturing, quality and regulatory affairs, CGT business operations, and more.<\/p>\n<p>\n        <b>For more information about the G-Rex\u00ae Grant Program, please contact <\/b><br \/>\n        <a href=\"mailto:info@scaleready.com\" target=\"_blank\" rel=\"nofollow\"><br \/>\n          <b>info@scaleready.com<\/b><br \/>\n        <\/a><br \/>\n        <b>.<\/b>\n      <\/p>\n<p>\n        <b>About ScaleReady<br \/><\/b>ScaleReady provides the field of cell and gene-modified cell therapy (CGT) with a G-Rex centric manufacturing platform that enables the world&#8217;s most practical, flexible, scalable, and affordable CGT drug product development and manufacturing.<\/p>\n<p>The G-Rex manufacturing platform is currently used by a rapidly growing list of over 800 organizations and is producing drug products for approximately 50% of CGT clinical trials as well as 5 commercially approved CGT drugs.<\/p>\n<p>CGT entities relying on the breadth and scope of ScaleReady&#8217;s expertise can expect to save years of time and millions of dollars on the path to CGT commercialization.<\/p>\n<p>For more information about the ScaleReady G-Rex\u00ae Grant Program, please contact <a href=\"mailto:info@scaleready.com\" rel=\"nofollow\">info@scaleready.com<\/a>.<\/p>\n<p>\n        <b>About Wilson Wolf Manufacturing<br \/><\/b><br \/>\n        <span class=\"xn-person\">Wilson Wolf<\/span> (<a href=\"http:\/\/www.wilsonwolf.com\" rel=\"nofollow\">www.wilsonwolf.com<\/a>) is dedicated to simplifying cell and gene-modified cell (CGT) therapy research, process development, and manufacturing. This is being accomplished through its scalable G-Rex technology, which is used throughout the world in CGT applications ranging from basic research to commercial drug production.<\/p>\n<p>\n        <span class=\"xn-person\">Wilson Wolf&#8217;s<\/span> mission is to create hope for cancer patients, one G-Rex\u00ae device at a time.<\/p>\n<p>\n        <b>About Bio-Techne Corporation<br \/><\/b>Bio-Techne Corporation (NASDAQ: TECH) is a global life sciences company providing innovative tools and bioactive reagents for the research and clinical diagnostic communities. Bio-Techne, in partnership with <span class=\"xn-person\">Wilson Wolf<\/span>, is creating products such as media and cytokines that are specifically tailored to G-Rex\u00ae Bioreactors, including right-sized reagent quantities in containers that are tailored to high throughput closed-system manufacturing. For more information on Bio-Techne and its brands, please visit <a href=\"https:\/\/www.bio-techne.com\" rel=\"nofollow\">https:\/\/www.bio-techne.com<\/a> or follow the Company on social media at: Facebook, LinkedIn, Twitter or YouTube.<\/p>\n<p>Contact: <span class=\"xn-person\">David Clair<\/span>, Vice President, Investor Relations &amp; Corporate Development<br \/><a href=\"mailto:david.clair@bio-techne.com\" target=\"_blank\" rel=\"nofollow\">david.clair@bio-techne.com<\/a><br \/>612-656-4416<\/p>\n<p>\n        <b>About CellReady LLC<br \/><\/b>CellReady is the world&#8217;s first and only G-Rex centric contract development and manufacturing organization (CDMO) specializing in G-Rex based cell and gene-modified cell therapy development and manufacturing. The company offers a wide range of services to support the development and commercialization of these therapies.<\/p>\n<p>CellReady&#8217;s mission is to create hope for cancer patients, one G-Rex\u00ae process at a time.<\/p>\n<p>\n        <b>About BrainChild Bio<br \/><\/b>BrainChild Bio, Inc., is a kids-first, clinical-stage biotechnology company harnessing the power of CAR T-cell technology to treat tumors in the central nervous system, prioritizing pediatric indications with plans to expand into adult CNS tumors, specifically Glioblastoma and Brain Metastasis. BrainChild Bio is advancing a next-generation CAR T-cell therapy platform for tumors of the CNS that weaves together synthetic technologies, including multiplex targeting and enhanced potency controls, to enable multiple targets in a single CAR T-cell therapy, novel transgenes to increase potency, delivery technology for durable efficacy, and streamlined CAR T-cell design and manufacturing. BrainChild Bio&#8217;s lead drug candidate is BCB-276, an autologous CAR T-cell therapy that targets the immune checkpoint B7-H3, that is advancing in clinical trials for the treatment of diffuse intrinsic pontine glioma (DIPG), a pediatric cancer that forms in the brainstem which currently has no approved treatments. More information is available at\u00a0<a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=4344244-1&amp;h=159220088&amp;u=https%3A%2F%2Fcts.businesswire.com%2Fct%2FCT%3Fid%3Dsmartlink%26url%3Dhttp%253A%252F%252Fwww.brainchildbio.com%26esheet%3D54174240%26newsitemid%3D20250106302628%26lan%3Den-US%26anchor%3Dwww.brainchildbio.com%26index%3D2%26md5%3D2133f4064cf8099dd8c9a0a23aa4da28&amp;a=www.brainchildbio.com\" target=\"_blank\" rel=\"nofollow\">www.brainchildbio.com<\/a><\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder2198\">\n<p>\n          <a href=\"https:\/\/mma.prnewswire.com\/media\/2541888\/ScaleReady_Logo_RGB__2___002.html\" target=\"_blank\" rel=\"nofollow\"><br \/>\n            <img decoding=\"async\" src=\"https:\/\/mma.prnewswire.com\/media\/2541888\/ScaleReady_Logo_RGB__2___002.jpg\" title=\"ScaleReady Logo (PRNewsfoto\/Bio-Techne Corporation)\" alt=\"ScaleReady Logo (PRNewsfoto\/Bio-Techne Corporation)\" \/><br \/>\n          <\/a>\n        <\/p>\n<\/p><\/div>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder0\"><\/div>\n<p id=\"PURL\">\n        <img loading=\"lazy\" decoding=\"async\" title=\"Cision\" width=\"12\" height=\"12\" alt=\"Cision\" src=\"https:\/\/c212.net\/c\/img\/favicon.png?sn=CG00168&amp;sd=2025-01-21\" \/> View original content to download multimedia:<a id=\"PRNURL\" rel=\"nofollow\" href=\"https:\/\/www.prnewswire.com\/news-releases\/scaleready-announces-a-g-rex-grant-has-been-awarded-to-brainchild-bio-302355642.html\" target=\"_blank\">https:\/\/www.prnewswire.com\/news-releases\/scaleready-announces-a-g-rex-grant-has-been-awarded-to-brainchild-bio-302355642.html<\/a><\/p>\n<p>SOURCE  Bio-Techne Corporation<\/p>\n<\/p><\/div>\n<p>    <img decoding=\"async\" alt=\"\" src=\"https:\/\/rt.prnewswire.com\/rt.gif?NewsItemId=CG00168&amp;Transmission_Id=202501210700PR_NEWS_USPR_____CG00168&amp;DateId=20250121\" style=\"border:0px;width:1px;height:1px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>PR Newswire ST. PAUL, Minn. , Jan. 21, 2025 \/PRNewswire\/ &#8212; ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation and CellReady, today announced that BrainChild Bio has been awarded a $300,000 G-Rex\u00ae Grant. The G-Rex\u00ae Grant will support expeditious process development and commercial readiness of BCB-276, BrainChild Bio&#8217;s lead autologous CAR-T therapy for the treatment of diffuse intrinsic pontine glioma (DIPG), an incurable type of pediatric brain tumor. BrainChild Bio plans to advance BCB-276 into a multi-center Phase 2 pivotal clinical trial in 2025 for the treatment of children and young adults with DIPG. &#8220;G-Rex has been an essential element of our clinical CAR-T manufacturing program at Seattle Children&#8217;s dating back to 2012. We greatly appreciate the support of &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-announces-a-g-rex-grant-has-been-awarded-to-brainchild-bio\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;ScaleReady Announces a G-Rex\u00ae Grant has been awarded to BrainChild Bio&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-802500","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ScaleReady Announces a G-Rex\u00ae Grant has been awarded to BrainChild Bio - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/scaleready-announces-a-g-rex-grant-has-been-awarded-to-brainchild-bio\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ScaleReady Announces a G-Rex\u00ae Grant has been awarded to BrainChild Bio - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"PR Newswire ST. PAUL, Minn. , Jan. 21, 2025 \/PRNewswire\/ &#8212; ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation and CellReady, today announced that BrainChild Bio has been awarded a $300,000 G-Rex\u00ae Grant. The G-Rex\u00ae Grant will support expeditious process development and commercial readiness of BCB-276, BrainChild Bio&#8217;s lead autologous CAR-T therapy for the treatment of diffuse intrinsic pontine glioma (DIPG), an incurable type of pediatric brain tumor. BrainChild Bio plans to advance BCB-276 into a multi-center Phase 2 pivotal clinical trial in 2025 for the treatment of children and young adults with DIPG. &#8220;G-Rex has been an essential element of our clinical CAR-T manufacturing program at Seattle Children&#8217;s dating back to 2012. 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PAUL, Minn. , Jan. 21, 2025 \/PRNewswire\/ &#8212; ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation and CellReady, today announced that BrainChild Bio has been awarded a $300,000 G-Rex\u00ae Grant. The G-Rex\u00ae Grant will support expeditious process development and commercial readiness of BCB-276, BrainChild Bio&#8217;s lead autologous CAR-T therapy for the treatment of diffuse intrinsic pontine glioma (DIPG), an incurable type of pediatric brain tumor. BrainChild Bio plans to advance BCB-276 into a multi-center Phase 2 pivotal clinical trial in 2025 for the treatment of children and young adults with DIPG. &#8220;G-Rex has been an essential element of our clinical CAR-T manufacturing program at Seattle Children&#8217;s dating back to 2012. 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