{"id":800078,"date":"2025-01-13T09:30:43","date_gmt":"2025-01-13T14:30:43","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\/"},"modified":"2025-01-13T09:30:43","modified_gmt":"2025-01-13T14:30:43","slug":"emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\/","title":{"rendered":"Emergent BioSolutions Receives Contract Option Valued at Approximately $16.7 Million to Continue Development Collaboration with BARDA on Ebanga\u2122 (ansuvimab-zykl) Treatment for Ebola"},"content":{"rendered":"<div class=\"mw_release\">\n<ul type=\"disc\">\n<li style=\"margin-bottom:8pt\">This option is part of Emergent\u2019s existing 10-year contract with BARDA for advanced development and procurement of Ebanga\u2122, with a maximum value of $704 million<\/li>\n<li style=\"margin-bottom:8pt\">Program progress and performance triggers $16.7 million contract option<\/li>\n<\/ul>\n<p>GAITHERSBURG, Md., Jan.  13, 2025  (GLOBE NEWSWIRE) &#8212; Emergent BioSolutions Inc.\u00a0(NYSE: EBS) announced today that the\u00a0Biomedical Advanced Research and Development Authority\u00a0(BARDA), part of the Administration for Strategic Preparedness and Response within the\u00a0U.S. Department of Health and Human Services, executed a contract modification for the second option period, valued at\u00a0approximately $16.7 million, for drug product process and analytical testing validation and long-term stability for Ebanga\u2122 (ansuvimab-zykl). Ebanga\u2122 is indicated for the treatment of infection caused by Zaire Ebola virus.<\/p>\n<p>\u201cWe are delighted our continued collaboration with BARDA is advancing Ebanga\u2122 development toward supplying treatment and ensuring communities are prepared against Ebola,\u201d said\u00a0Simon Lowry, M.D., chief medical officer, head of research and development, Emergent. \u201cEbola is a devastating infectious illness with limited treatment options. This important work reinforces Emergent\u2019s leadership in developing solutions to address priority public health threats.\u201d<\/p>\n<p>The existing\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=FRrGz5dnxh9TBZ2B-x8w-86BVtqJ4prJCb5ibd7jXvJylDL8tK-MkgQTmsMUtzHEWsi39gHjzVjWwj7f9kYJHeecGXw2bSdCjU9ZpctSczfyI565rUMddE1nlOfchk_39WNlatz33wzV3f_AUY5eVZVllKAYgjj9YzmV9U8-W9TNPxYqHioH8qwGuqXlgz5PCIaRXVEDzCqojAjKuTmC3ZVCMW6_Rn6bdBnpzspbYZmOim4gL0UAsvEtqLOT_0aLkOGhus_u5DIM0QnLzbzvwMMJPQDnZ-b99cK1nmoJU570ia7u7qmU9wUEZ-B3fi6uOmhl3zqZ3aoRKK9G8kW-4n-WHnishJ4LFO8AGYsPvqShtWiVyIK9E6yBxHZZdPUXRtWmsTsRkeyfX190zueOEwvIG0ONBK19YfylYd9z7hMC8beKhKTxr7xlWFA3fAZJTWGibzxh0FFbJ09rTBVb5A==\" rel=\"nofollow\" target=\"_blank\">10-year contract<\/a>\u00a0consists of a base period of performance with two option periods for advanced development valued at approximately\u00a0$118 million, and option periods for procurement of Ebanga\u2122 treatment over five years valued at up to\u00a0$583 million. Under the terms of the contract, Emergent will complete activities to advance the development of Ebanga\u2122 through post-licensure commitments. These activities include manufacturing scale-up, transferring manufacturing technology, and completing stability studies, as well as the submission of a supplemental Biologics License Application to the\u00a0U.S. Food and Drug Administration.<\/p>\n<p>This project has been funded in whole or in part with federal funds from the\u00a0Department of Health and Human Services; Administration for Strategic Preparedness and Response;\u00a0Biomedical Advanced Research and Development Authority\u00a0under contract 75A50123C00037.<\/p>\n<p>\n        <strong>About Ebanga\u2122<\/strong><br \/>\n        \n      <\/p>\n<p>\n        <strong>Indication<\/strong>\n      <\/p>\n<p>Ebanga\u2122 (ansuvimab-zykl) is a <em>Zaire ebolavirus <\/em>glycoprotein (EBOV GP)-directed human monoclonal antibody indicated for the treatment of infection caused by Zaire ebolavirus in adult and pediatric patients, including neonates born to a mother who is RT-PCR positive for <em>Zaire ebolavirus<\/em> infection.<\/p>\n<p>Limitations of Use:<\/p>\n<p>The efficacy of Ebanga\u2122 has not been established for other species of the <em>Ebolavirus<\/em> and <em>Marburgvirus<\/em> genera.<\/p>\n<p>\n        <em>Zaire ebolavirus<\/em> can change over time, and factors such as emergence of resistance or changes in viral virulence could diminish the clinical benefit of antiviral drugs. Consider available information on drug susceptibility patterns for circulating <em>Zaire ebolavirus<\/em> strains when deciding whether to use Ebanga\u2122.<\/p>\n<p>\n        <strong>Important Safety Information<\/strong>\n      <\/p>\n<p>\n        <strong>Hypersensitivity Reactions Including Infusion-Associated Events:<\/strong> Hypersensitivity reactions including infusion-associated events have been reported with Ebanga\u2122. These may include acute, life-threatening reactions during and after the infusion. Monitor all patients for signs and symptoms including, but not limited to, hypotension, chills and elevation of fever, during and following Ebanga\u2122 infusion. In the case of severe or life-threatening hypersensitivity reactions, discontinue the administration of Ebanga\u2122 immediately and administer appropriate emergency care.<\/p>\n<p>\n        <strong>Adverse reactions:<\/strong> The most frequently reported adverse events (\u2265 5%) after administration of Ebanga\u2122 were pyrexia (fever), tachycardia, diarrhea, vomiting, hypotension, tachypnea, and chills. The adverse event profile in adult and pediatric (birth to less than 18 years of age) subjects treated with Ebanga\u2122 was similar.<\/p>\n<p>\n        <strong>U.S. Prescribing Information<\/strong>\n      <\/p>\n<p>The full Prescribing Information for Ebanga<strong>\u2122<\/strong> vaccine can be found <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=szhgxnrlEiP9blYLJ9zd6_w0vH4Jw2u1nN3iwRq66Aidvoha73x5HJjfcHHNbhU6S4EpsZdtAOoweyL7PrkGmGqCLcjRJkpYV1bPqkb_9VjvZa2a5iUdTdMlmySLTEN77WZWIrLZfKfrdBXevOFJzUqcB6Jrk8hxMBe0SIAbsHo=\" rel=\"nofollow\" target=\"_blank\">here<\/a>.<\/p>\n<p>\n        <strong>About Ebola Virus Disease<\/strong><br \/>\n        <br \/>\n        <em>Orthoebolavirus zairense<\/em>, referred to as Ebola virus disease (EVD) is severe and often fatal with case fatality rates ranging from 25% to 90%, and is transmitted via bodily fluids, zoonotic transmission, or contact with contaminated surfaces. The\u00a0U.S. Department of Homeland Security\u00a0has determined that EVD poses a material threat to national health security. To augment the\u00a0U.S.\u00a0government\u2019s response capabilities, BARDA is pursuing advanced development, licensure, and procurement of therapeutics that can be deployed in outbreaks.<\/p>\n<p>\n        <strong>About\u00a0Emergent BioSolutions<\/strong><br \/>\n        <br \/>At Emergent, our mission is to protect and enhance life. For over 25 years, we\u2019ve been at work defending people from things we hope will never happen\u2014so we are prepared just in case they ever do. We provide solutions for complex and urgent public health threats through a portfolio of vaccines and therapeutics that we develop and manufacture for governments and consumers. We also offer a range of integrated contract development and manufacturing services for pharmaceutical and biotechnology customers. To learn more about how we plan to protect or enhance 1 billion lives by 2030, visit our\u202f<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=2E1xmOxFj-7Vh_Mv2hGgw8y6Hic0j0HS-feIh9lLvDWGsPhi2jh1JFPkyedmbmbI8qJeiBiGD18KQqueQGYtK-VbDCRRVUZX7NLMJdPOddk=\" rel=\"nofollow\" target=\"_blank\">website<\/a>\u202fand follow us on\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=143qm2VIf1K9PuxK58ooVgBIgvxjDzCOGKKHsG5NX_oBbkdNY2xL4ToMg7gANYbk9w170afk1RAWJEg8nrs8UBsENI5pgsRiMwaZ_8lc5RPZmuOFW46ASHAnQG-YMwPW\" rel=\"nofollow\" target=\"_blank\">LinkedIn<\/a>,\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=s5_LcbvmwS6mywHWIQKYiiUl-g1oS8G7DUnaKKqlwx_h4sarDti1q7Jolhr8NM8P39k6i_y_qzCIO8wkmjKoJQ==\" rel=\"nofollow\" target=\"_blank\">X<\/a>,\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=g2kZSzDkLumkRCHdWv4zZWZ0ncVn2qHLpr7duHxuS37waOxqDPAEJjteITJKgBWcf289dfgiiXo2EYl8eomdMQgOCW3bxQLMa0NvTFlMvgM=\" rel=\"nofollow\" target=\"_blank\">Instagram<\/a>,\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=fcrcPMMpRzbS9P28pyGFpmh3qmUckg007_SKTLmN8iAmkPJBdhY2TdNGy7IEyekwpnkj55dvioU_TOPuc5bFqJnPf8kRUn22uSolSnx1UgKoJlYu3666jSVibuQULfiEmu3PwIwwXzzWRCMv7lLPOg==\" rel=\"nofollow\" target=\"_blank\">Apple Podcasts<\/a>\u00a0and\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=RaylncuPC1xWQ5oHdnJtZFy4FgM9PVI8V_2Oj9Bf24C8M8DVAnAu14uO5Wc6CBjW8e-LrKW_00SfoxXM-3kbnX0fOckS-cRQbaYhCSotDz1dPjD_UTszc3xz-33v3s550R7po1O1qRx83xCauiahWKn6mz3417WG3RqJ4nE1eohmROdXstawf2hNWR94_yBK\" rel=\"nofollow\" target=\"_blank\">Spotify<\/a>.<\/p>\n<p>\n        <strong>Safe Harbor Statement<\/strong><br \/>\n        <br \/>This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical fact, including statements regarding the agreement with BARDA for the advanced development, manufacturing scale-up, and procurement of Ebanga\u2122 treatment, including the potential exercise of option periods and any payments in connection therewith, are forward-looking statements. We generally identify forward-looking statements by using words like \u201canticipate,\u201d \u201cbelieve,\u201d \u201ccontinue,\u201d \u201ccould,\u201d \u201cestimate,\u201d \u201cexpect,\u201d \u201cforecast,\u201d \u201cgoal,\u201d \u201cintend,\u201d \u201cmay,\u201d \u201cplan,\u201d \u201cshould,\u201d \u201cwill,\u201d \u201cwould,\u201d and similar expressions or variations thereof, or the negative thereof, but these terms are not the exclusive means of identifying such statements. Forward-looking statements are based on Emergent\u2019s current intentions, beliefs, and expectations regarding future events. Emergent cannot guarantee that any forward-looking statement will be accurate. Readers should realize that if underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could differ materially from Emergent\u2019s expectations. Readers are, therefore, cautioned not to place undue reliance on any forward-looking statement. Any forward-looking statement speaks only as of the date of this press release, and, except as required by law, Emergent does not undertake to update any forward-looking statement to reflect new information, events or circumstances. There are a number of important factors that could cause Emergent\u2019s actual results to differ materially from those indicated by any forward-looking statements.<\/p>\n<p>Readers should consider this cautionary statement, as well as the risk factors identified in Emergent\u2019s periodic reports filed with the\u00a0U.S. Securities and Exchange Commission\u00a0when evaluating Emergent\u2019s forward-looking statements.<\/p>\n<p>\n        <strong>Investor Contact:<\/strong><br \/>\n        <br \/>Richard S. Lindahl<br \/>Executive Vice President, CFO<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=VBkfDIo1wZMnJ-q-gwhsFZTNqpJN8mBbmdYZ9MpcKYJX5eJk13McNOrFH8RhOaz5zyYGkKW1zo27kRWXN0Pwfz-7_WfSzTd-mS0O4UeK0vs=\" rel=\"nofollow\" target=\"_blank\">lindahlr@ebsi.com<\/a>\u00a0<\/p>\n<p>\n        <strong>Media Contact:<\/strong><br \/>\n        <br \/>Assal Hellmer<br \/>Vice President, Communications<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=UBYrGZUfbk6g8wXyR44qonnOPTGbPgovcIry6VM0mvtpRXh91AHJGhrcAt-Z3NG1VfKxzovQ5-G719YwqbpYjnKPaKdBi9-pWVGmL0glqQI=\" rel=\"nofollow\" target=\"_blank\">mediarelations@ebsi.com<\/a>\u00a0<\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTMzMDk3NiM2NjkxMTk0IzIwMTA4NjY=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/MWRiOTAzYzctMTlmMi00YWQwLWE4MDAtOTRmMTgwMjQ1YjUxLTEwMjI0Mzk=\/tiny\/Emergent-Biosolutions-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>This option is part of Emergent\u2019s existing 10-year contract with BARDA for advanced development and procurement of Ebanga\u2122, with a maximum value of $704 million Program progress and performance triggers $16.7 million contract option GAITHERSBURG, Md., Jan. 13, 2025 (GLOBE NEWSWIRE) &#8212; Emergent BioSolutions Inc.\u00a0(NYSE: EBS) announced today that the\u00a0Biomedical Advanced Research and Development Authority\u00a0(BARDA), part of the Administration for Strategic Preparedness and Response within the\u00a0U.S. Department of Health and Human Services, executed a contract modification for the second option period, valued at\u00a0approximately $16.7 million, for drug product process and analytical testing validation and long-term stability for Ebanga\u2122 (ansuvimab-zykl). Ebanga\u2122 is indicated for the treatment of infection caused by Zaire Ebola virus. \u201cWe are delighted our continued collaboration with BARDA &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Emergent BioSolutions Receives Contract Option Valued at Approximately $16.7 Million to Continue Development Collaboration with BARDA on Ebanga\u2122 (ansuvimab-zykl) Treatment for Ebola&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-800078","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Emergent BioSolutions Receives Contract Option Valued at Approximately $16.7 Million to Continue Development Collaboration with BARDA on Ebanga\u2122 (ansuvimab-zykl) Treatment for Ebola - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Emergent BioSolutions Receives Contract Option Valued at Approximately $16.7 Million to Continue Development Collaboration with BARDA on Ebanga\u2122 (ansuvimab-zykl) Treatment for Ebola - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"This option is part of Emergent\u2019s existing 10-year contract with BARDA for advanced development and procurement of Ebanga\u2122, with a maximum value of $704 million Program progress and performance triggers $16.7 million contract option GAITHERSBURG, Md., Jan. 13, 2025 (GLOBE NEWSWIRE) &#8212; Emergent BioSolutions Inc.\u00a0(NYSE: EBS) announced today that the\u00a0Biomedical Advanced Research and Development Authority\u00a0(BARDA), part of the Administration for Strategic Preparedness and Response within the\u00a0U.S. Department of Health and Human Services, executed a contract modification for the second option period, valued at\u00a0approximately $16.7 million, for drug product process and analytical testing validation and long-term stability for Ebanga\u2122 (ansuvimab-zykl). Ebanga\u2122 is indicated for the treatment of infection caused by Zaire Ebola virus. \u201cWe are delighted our continued collaboration with BARDA &hellip; Continue reading &quot;Emergent BioSolutions Receives Contract Option Valued at Approximately $16.7 Million to Continue Development Collaboration with BARDA on Ebanga\u2122 (ansuvimab-zykl) Treatment for Ebola&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2025-01-13T14:30:43+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTMzMDk3NiM2NjkxMTk0IzIwMTA4NjY=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Emergent BioSolutions Receives Contract Option Valued at Approximately $16.7 Million to Continue Development Collaboration with BARDA on Ebanga\u2122 (ansuvimab-zykl) Treatment for Ebola\",\"datePublished\":\"2025-01-13T14:30:43+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\\\/\"},\"wordCount\":1035,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTMzMDk3NiM2NjkxMTk0IzIwMTA4NjY=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/emergent-biosolutions-receives-contract-option-valued-at-approximately-16-7-million-to-continue-development-collaboration-with-barda-on-ebanga-ansuvimab-zykl-treatment-for-ebola\\\/\",\"name\":\"Emergent BioSolutions Receives Contract Option Valued at Approximately $16.7 Million to Continue Development Collaboration with BARDA on Ebanga\u2122 (ansuvimab-zykl) Treatment for Ebola - 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