{"id":795745,"date":"2024-12-18T08:06:40","date_gmt":"2024-12-18T13:06:40","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/"},"modified":"2024-12-18T08:06:40","modified_gmt":"2024-12-18T13:06:40","slug":"alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/","title":{"rendered":"ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"left\">SOUTH SAN FRANCISCO, Calif., Dec.  18, 2024  (GLOBE NEWSWIRE) &#8212; ALX Oncology Holdings Inc. (\u201cALX Oncology\u201d or \u201cthe Company\u201d) (Nasdaq: ALXO), a clinical-stage biotechnology company advancing therapies that boost the immune system to treat cancer and extend patients\u2019 lives, today announced that the updated results from its Phase 2 ASPEN-06 clinical trial have been accepted for oral presentation at the 2025 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium, which will be held in San Francisco from January 23 &#8211; 25, 2025.<\/p>\n<p>ASPEN-06 is a randomized, multi-center, international trial (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=vfLscnuNIzGhJ9sikBQKEkdofqOkNADv7DMpLsetC1AsfBPK7CY9u78Z1_PW4VlS7KkcymTJN7sT1cuTOdOSM1BCkHQRoAWp4H28KkIqwEI=\" rel=\"nofollow\" target=\"_blank\">NCT05002127)<\/a> evaluating evorpacept, ALX Oncology\u2019s investigational CD47-blocking therapeutic that uniquely combines a high-affinity CD47-binding domain with an inactivated proprietary Fc domain, in combination with trastuzumab, CYRAMZA\u00ae\u00a0(ramucirumab) and paclitaxel (collectively, TRP) against TRP alone for the treatment of patients with HER2-positive gastric\/gastroesophageal junction cancer, where all patients had received an anti-HER2 agent in prior lines of therapy.<\/p>\n<p>The updated results from the ASPEN-06 study will be detailed in the following oral presentation:<\/p>\n<p>\n        <strong>Title: <\/strong><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=W1jl1a2d2PYlfrrrlocPmu9MfBa5xXFPraOYM7lXZEzcbtNgyzShJAvSDpIWMUFPb9AwLhlVUTNi2AId2d2blkOdbpvsEE2PqPMywQ9T0iyB_eOFEX61AAf_7puUmJxKfWO_aWmvMKXtg2DRSboMjcoam3vGh4C52AfYdocB3DqslohlrXaDQHLIGFf-rxPVp04QBGAZP7OS1LRK5JRmglRZAjdP5orMJZr3NsChoL4WbBNqPFgxjwYGIXdSZAaNhVaXk1gk65fdXLllviqeYnEgywxW3sxs3KM-FC96PcQRYndM025jtlNYazmSCV6iTv4dyQT5tTQ2XfpKC-7lSNneM1x_VqIgZXpmD7gNHmz3tOFd4BuwuYCHyFQCResWictMEZISaVVIwAwT7oEig3aSVla6EacVlMLVLN1fr8vTgtBwkBbKVENvbYYt5y6XpNNGdLb5I5r4_Fo6HmWShw==\" rel=\"nofollow\" target=\"_blank\"><br \/>\n          <u>Final analysis of the randomized phase 2 part of the ASPEN-06 study: A phase 2\/3 study of evorpacept (ALX148), a CD47 myeloid checkpoint inhibitor, in patients with HER2-overexpressing gastric\/gastroesophageal cancer (GC)<\/u><br \/>\n        <\/a><br \/>\n        <br \/>\n        <strong>Abstract Number:<\/strong> 332<br \/><strong>Presenter:<\/strong> Kohei\u00a0Shitara, MD, Director of the Department of Gastrointestinal Oncology, at National Cancer Center Hospital East, Kashiwa in Japan<br \/><strong>Presentation Date and Time:<\/strong> Thursday, January 23, 2025, from 9:15 a.m. \u2013 10:00 a.m. PST<br \/><strong>Session Information:<\/strong> Rapid Oral Abstract Session A: Cancers of the Esophagus and Stomach<br \/><strong>Location:<\/strong> Level 2 Ballroom<\/p>\n<p>Copies of the presentations will be available on the <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=jCi8gz-YxFCJ5wW7zgGtPX9N4ctPRv-7zveIt10cB69JG4Vn1LqoW-gkDJ8ZFRgc6fcN9xliq-PYb_BSwdDcRvlPuTGOzemcZPfySW-MFTqIUItdr0vkN-dKG-GY_hFJ\" rel=\"nofollow\" target=\"_blank\"><u>Publications<\/u><\/a> section of ALX Oncology\u2019s website following presentation at the meeting.<\/p>\n<p>\n        <strong>About ALX Oncology<\/strong><br \/>\n        <br \/>ALX Oncology (Nasdaq: ALXO) is a clinical-stage biotechnology company advancing therapies that boost the immune system to treat cancer and extend patients\u2019 lives. ALX Oncology\u2019s lead therapeutic candidate, evorpacept, has demonstrated potential to serve as a cornerstone therapy upon which the future of immuno-oncology can be built. Evorpacept is currently being evaluated across multiple ongoing clinical trials in a wide range of cancer indications. More information is available at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=WYptm5-cYNBgdVvmzwAPiQTCJIEoVztbNv7nH1trCeLHgILWmPwgX8S0v9-blRDUQAPndhrKgIf0nxCsEpvlwTzhniHcQFYW2DTYdexSkQY=\" rel=\"nofollow\" target=\"_blank\"><u>www.alxoncology.com<\/u><\/a> and on LinkedIn @<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=zsXc6ZsIOVGzyNbugVJBU9PyGo03hHVGKrB5RAr2PP-n2eK20oDpwDAfrSPeDAcjmaIurY-3pC89_lMHjHljJehLl8jyFYTOi-vepr2ggYYxmVBm80bv4F64QSno_yo9\" rel=\"nofollow\" target=\"_blank\"><u>ALX Oncology<\/u><\/a>.<\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTMyMDY1MSM2NjQxNTA4IzIxOTI4NjM=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/NzgwOTBjNTItMDExNS00Yzk2LWI1NDYtNmM2MTRhMmNmODg1LTEyMDQ0MTY=\/tiny\/ALX-Oncology.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\">\n<pre>Company Contact:\r\nCaitlyn Doherty, Manager, Corporate Communications, ALX Oncology\r\ncdoherty@alxoncology.com\r\n(650) 466-7125\r\n\r\nMedia Contact:\r\nAudra Friis, Sam Brown, Inc.\r\naudrafriis@sambrown.com\r\n(917) 519-9577<\/pre>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>SOUTH SAN FRANCISCO, Calif., Dec. 18, 2024 (GLOBE NEWSWIRE) &#8212; ALX Oncology Holdings Inc. (\u201cALX Oncology\u201d or \u201cthe Company\u201d) (Nasdaq: ALXO), a clinical-stage biotechnology company advancing therapies that boost the immune system to treat cancer and extend patients\u2019 lives, today announced that the updated results from its Phase 2 ASPEN-06 clinical trial have been accepted for oral presentation at the 2025 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium, which will be held in San Francisco from January 23 &#8211; 25, 2025. ASPEN-06 is a randomized, multi-center, international trial (NCT05002127) evaluating evorpacept, ALX Oncology\u2019s investigational CD47-blocking therapeutic that uniquely combines a high-affinity CD47-binding domain with an inactivated proprietary Fc domain, in combination with trastuzumab, CYRAMZA\u00ae\u00a0(ramucirumab) and paclitaxel (collectively, TRP) &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-795745","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"SOUTH SAN FRANCISCO, Calif., Dec. 18, 2024 (GLOBE NEWSWIRE) &#8212; ALX Oncology Holdings Inc. (\u201cALX Oncology\u201d or \u201cthe Company\u201d) (Nasdaq: ALXO), a clinical-stage biotechnology company advancing therapies that boost the immune system to treat cancer and extend patients\u2019 lives, today announced that the updated results from its Phase 2 ASPEN-06 clinical trial have been accepted for oral presentation at the 2025 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium, which will be held in San Francisco from January 23 &#8211; 25, 2025. ASPEN-06 is a randomized, multi-center, international trial (NCT05002127) evaluating evorpacept, ALX Oncology\u2019s investigational CD47-blocking therapeutic that uniquely combines a high-affinity CD47-binding domain with an inactivated proprietary Fc domain, in combination with trastuzumab, CYRAMZA\u00ae\u00a0(ramucirumab) and paclitaxel (collectively, TRP) &hellip; Continue reading &quot;ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2024-12-18T13:06:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTMyMDY1MSM2NjQxNTA4IzIxOTI4NjM=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium\",\"datePublished\":\"2024-12-18T13:06:40+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\\\/\"},\"wordCount\":372,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTMyMDY1MSM2NjQxNTA4IzIxOTI4NjM=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\\\/\",\"name\":\"ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/","og_locale":"en_US","og_type":"article","og_title":"ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium - Market Newsdesk","og_description":"SOUTH SAN FRANCISCO, Calif., Dec. 18, 2024 (GLOBE NEWSWIRE) &#8212; ALX Oncology Holdings Inc. (\u201cALX Oncology\u201d or \u201cthe Company\u201d) (Nasdaq: ALXO), a clinical-stage biotechnology company advancing therapies that boost the immune system to treat cancer and extend patients\u2019 lives, today announced that the updated results from its Phase 2 ASPEN-06 clinical trial have been accepted for oral presentation at the 2025 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium, which will be held in San Francisco from January 23 &#8211; 25, 2025. ASPEN-06 is a randomized, multi-center, international trial (NCT05002127) evaluating evorpacept, ALX Oncology\u2019s investigational CD47-blocking therapeutic that uniquely combines a high-affinity CD47-binding domain with an inactivated proprietary Fc domain, in combination with trastuzumab, CYRAMZA\u00ae\u00a0(ramucirumab) and paclitaxel (collectively, TRP) &hellip; Continue reading \"ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/","og_site_name":"Market Newsdesk","article_published_time":"2024-12-18T13:06:40+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTMyMDY1MSM2NjQxNTA4IzIxOTI4NjM=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium","datePublished":"2024-12-18T13:06:40+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/"},"wordCount":372,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTMyMDY1MSM2NjQxNTA4IzIxOTI4NjM=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/alx-oncology-to-present-updated-results-from-phase-2-aspen-06-clinical-trial-of-evorpacept-in-patients-with-her2-positive-gastric-cancer-in-oral-presentation-at-2025-asco-gastrointestinal-cancers-symp\/","name":"ALX Oncology to Present Updated Results from Phase 2 ASPEN-06 Clinical Trial of Evorpacept in Patients with HER2-Positive Gastric Cancer in Oral Presentation at 2025 ASCO Gastrointestinal Cancers Symposium - 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