{"id":790333,"date":"2024-11-25T07:33:57","date_gmt":"2024-11-25T12:33:57","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/"},"modified":"2024-11-25T07:33:57","modified_gmt":"2024-11-25T12:33:57","slug":"anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/","title":{"rendered":"Anavex Life Sciences Announces Acceptance of Peer-Reviewed Manuscript of Oral Blarcamesine Phase IIb\/III Data in a Reference Alzheimer\u2019s Disease Journal"},"content":{"rendered":"
\n

NEW YORK, Nov. 25, 2024 (GLOBE NEWSWIRE) — Anavex Life Sciences Corp. (\u201cAnavex\u201d or the \u201cCompany\u201d) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of Alzheimer’s disease, Parkinson’s disease, schizophrenia, neurodevelopmental, neurodegenerative, and rare diseases, including Rett syndrome, and other central nervous system (CNS) diseases, today announced the acceptance of a peer-reviewed manuscript titled, \u201cBlarcamesine for the treatment of Early Alzheimer\u2019s Disease: Results from the ANAVEX2-73-AD-004 Phase IIB\/III trial<\/em>,\u201d in a medical journal with focus on Alzheimer\u2019s disease. The publication date is expected around Q4 2024\/Q1 2025.<\/p>\n

\u201cThe publication in a peer-reviewed medical journal is an important milestone for the Anavex team and is a testament to the importance of the findings for the scientific and Alzheimer\u2019s disease communities,\u201d said Juan Carlos Lopez-Talavera, MD, PhD, Head of Research and Development of Anavex. \u201cWe are on track for regulatory submission of oral blarcamesine in Europe (EMA) in the current quarter 2024.\u201d<\/p>\n

\u201cWe are honored to be sharing this peer-reviewed manuscript in an international journal,\u201d said Christopher U. Missling, PhD, President and Chief Executive Officer of Anavex. \u201cAlzheimer\u2019s disease is such a devastating disease that affects tens of millions worldwide and this forthcoming publication could be helpful to educate the medical and scientific community about the potential of oral blarcamesine for patients with Alzheimer’s disease.\u201d<\/p>\n

This release discusses investigational uses of an agent in development and is not intended to convey conclusions about efficacy or safety. There is no guarantee that any investigational uses of such product will successfully complete clinical development or gain health authority approval.<\/p>\n

\n About Alzheimer\u2019s Disease<\/strong>\n <\/p>\n

There are an estimated 7 million people in Europe with Alzheimer\u2019s disease, a number expected to double by 2030, according to the European Brain Council.1<\/sup> The World Health Organization (WHO) estimated the cost in Europe of caring for people with dementia, including Alzheimer’s disease, at $439 billion, or $31,144 per person in 2019. That includes hospital care, medicines, diagnostics, informal caregiver time, community services and long-term care facility costs.2<\/sup>,<\/sup>3<\/sup><\/p>\n

\n About Anavex Life Sciences Corp.<\/strong>\n <\/p>\n

Anavex Life Sciences Corp. (Nasdaq: AVXL) is a publicly traded biopharmaceutical company dedicated to the development of novel therapeutics for the treatment of neurodegenerative, neurodevelopmental, and neuropsychiatric disorders, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, Rett syndrome, and other central nervous system (CNS) diseases, pain, and various types of cancer. Anavex’s lead drug candidate, ANAVEX\u00ae<\/sup>2-73 (blarcamesine<\/em>), has successfully completed a Phase 2a and a Phase 2b\/3 clinical trial for Alzheimer’s disease, a Phase 2 proof-of-concept study in Parkinson’s disease dementia, and both a Phase 2 and a Phase 3 study in adult patients and one Phase 2\/3 study in pediatric patients with Rett syndrome. ANAVEX\u00ae<\/sup>2-73 is an orally available drug candidate designed to restore cellular homeostasis by targeting SIGMAR1 and muscarinic receptors. Preclinical studies demonstrated its potential to halt and\/or reverse the course of Alzheimer’s disease. ANAVEX\u00ae<\/sup>2-73 also exhibited anticonvulsant, anti-amnesic, neuroprotective, and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy. The Michael J. Fox Foundation for Parkinson’s Research previously awarded Anavex a research grant, which fully funded a preclinical study to develop ANAVEX\u00ae<\/sup>2-73 for the treatment of Parkinson’s disease. We believe that ANAVEX\u00ae<\/sup>3-71, which targets SIGMAR1 and M1 muscarinic receptors, is a promising clinical stage drug candidate demonstrating disease-modifying activity against the major hallmarks of Alzheimer’s disease in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid, and tau pathologies. In preclinical trials, ANAVEX\u00ae<\/sup>3-71 has shown beneficial effects on mitochondrial dysfunction and neuroinflammation. Further information is available at www.anavex.com<\/a>. You can also connect with the Company on Twitter,<\/a>Facebook<\/a>, Instagram<\/a>, and LinkedIn<\/a>.<\/p>\n

\n Forward-Looking Statements<\/strong>\n <\/p>\n

Statements in this press release that are not strictly historical in nature are forward-looking statements. These statements are only predictions based on current information and expectations and involve a number of risks and uncertainties. Actual events or results may differ materially from those projected in any of such statements due to various factors, including the risks set forth in the Company\u2019s most recent Annual Report on Form 10-K filed with the SEC. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement and Anavex Life Sciences Corp. undertakes no obligation to revise or update this press release to reflect events or circumstances after the date hereof.<\/p>\n

\n For Further Information:<\/strong>
\n
Anavex Life Sciences Corp.
Research & Business Development
Toll-free: 1-844-689-3939
Email: info@anavex.com<\/a><\/p>\n

\n Investors:<\/strong>
\n
Andrew J. Barwicki
Investor Relations
Tel: 516-662-9461
Email: andrew@barwicki.com<\/a><\/p>\n

\n 1<\/sup> https:\/\/www.braincouncil.eu\/projects\/rethinking-alzheimers-disease\/
2<\/sup> J\u00f6nsson L. The personal economic burden of dementia in Europe. Lancet Reg Health Eur. 2022 Jul 25;20:100472. doi: 10.1016\/j.lanepe.2022.100472. PMID: 35910037; PMCID: PMC9326307.
3<\/sup> World Health Organization (WHO); 2021. Global status report on the public health response to dementia.<\/p>\n

\"\"
\n
\n \"\"\n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

NEW YORK, Nov. 25, 2024 (GLOBE NEWSWIRE) — Anavex Life Sciences Corp. (\u201cAnavex\u201d or the \u201cCompany\u201d) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of Alzheimer’s disease, Parkinson’s disease, schizophrenia, neurodevelopmental, neurodegenerative, and rare diseases, including Rett syndrome, and other central nervous system (CNS) diseases, today announced the acceptance of a peer-reviewed manuscript titled, \u201cBlarcamesine for the treatment of Early Alzheimer\u2019s Disease: Results from the ANAVEX2-73-AD-004 Phase IIB\/III trial,\u201d in a medical journal with focus on Alzheimer\u2019s disease. The publication date is expected around Q4 2024\/Q1 2025. \u201cThe publication in a peer-reviewed medical journal is an important milestone for the Anavex team and is a testament to the importance of the findings for the scientific and … <\/p>\n

Continue reading “Anavex Life Sciences Announces Acceptance of Peer-Reviewed Manuscript of Oral Blarcamesine Phase IIb\/III Data in a Reference Alzheimer\u2019s Disease Journal”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-790333","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nAnavex Life Sciences Announces Acceptance of Peer-Reviewed Manuscript of Oral Blarcamesine Phase IIb\/III Data in a Reference Alzheimer\u2019s Disease Journal - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Anavex Life Sciences Announces Acceptance of Peer-Reviewed Manuscript of Oral Blarcamesine Phase IIb\/III Data in a Reference Alzheimer\u2019s Disease Journal - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"NEW YORK, Nov. 25, 2024 (GLOBE NEWSWIRE) — Anavex Life Sciences Corp. 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(\u201cAnavex\u201d or the \u201cCompany\u201d) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of Alzheimer’s disease, Parkinson’s disease, schizophrenia, neurodevelopmental, neurodegenerative, and rare diseases, including Rett syndrome, and other central nervous system (CNS) diseases, today announced the acceptance of a peer-reviewed manuscript titled, \u201cBlarcamesine for the treatment of Early Alzheimer\u2019s Disease: Results from the ANAVEX2-73-AD-004 Phase IIB\/III trial,\u201d in a medical journal with focus on Alzheimer\u2019s disease. The publication date is expected around Q4 2024\/Q1 2025. \u201cThe publication in a peer-reviewed medical journal is an important milestone for the Anavex team and is a testament to the importance of the findings for the scientific and … Continue reading \"Anavex Life Sciences Announces Acceptance of Peer-Reviewed Manuscript of Oral Blarcamesine Phase IIb\/III Data in a Reference Alzheimer\u2019s Disease Journal\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/","og_site_name":"Market Newsdesk","article_published_time":"2024-11-25T12:33:57+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTI4OTIwMCM2NjA4NTg5IzIwMTk1Mzk=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Anavex Life Sciences Announces Acceptance of Peer-Reviewed Manuscript of Oral Blarcamesine Phase IIb\/III Data in a Reference Alzheimer\u2019s Disease Journal","datePublished":"2024-11-25T12:33:57+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/"},"wordCount":822,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTI4OTIwMCM2NjA4NTg5IzIwMTk1Mzk=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/anavex-life-sciences-announces-acceptance-of-peer-reviewed-manuscript-of-oral-blarcamesine-phase-iib-iii-data-in-a-reference-alzheimers-disease-journal\/","name":"Anavex Life Sciences Announces Acceptance of Peer-Reviewed Manuscript of Oral Blarcamesine Phase IIb\/III Data in a Reference Alzheimer\u2019s Disease Journal - 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