{"id":768836,"date":"2023-07-11T07:32:32","date_gmt":"2023-07-11T11:32:32","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/"},"modified":"2023-07-11T07:32:32","modified_gmt":"2023-07-11T11:32:32","slug":"caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/","title":{"rendered":"CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring"},"content":{"rendered":"

<\/p>\n

CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring<\/b><\/p>\n

AlloSure Lung Represents First dd-cfDNA Approved by Medicare for Lung Transplant Patients<\/i><\/p>\n

BRISBANE, Calif.–(BUSINESS WIRE<\/a>)–
\nCareDx, Inc. (Nasdaq: CDNA) \u2013 The Transplant Company\u2122 focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers \u2013 today announced that CareDx\u2019s AlloSure\u00ae Lung donor-derived cell-free DNA (dd-cfDNA) molecular testing service has received Medicare coverage.<\/p>\n

\nThe MolDX technology assessment program has determined that AlloSure Lung will be covered under the existing Medicare Local Coverage Determination for Molecular Testing for Solid Organ Allograft Rejection for use in the surveillance setting in lung transplant patients, effective May 9, 2023.1<\/sup><\/p>\n

\n\u201cCareDx was the first to receive MolDX coverage of dd-cfDNA with AlloSure for kidney and heart transplant patients, and we are now proud to be the first approved for lung transplant patients. We are 100% committed to transplant patients and today\u2019s milestone approval represents a monumental day for lung transplant patients,\u201d said Reg Seeto, CEO and President of CareDx. \u201cNotably, in 2021, we were the first in the field to deliver this type of non-invasive solution to monitor rejection in lung transplantation. We did so because of the significant unmet need where it is estimated that 1 in 2 lung transplant patients are expected to have their transplant fail five years post-transplant.\u201d<\/p>\n

\nThe clinical validity and utility of AlloSure Lung dd-cfDNA have been demonstrated in multiple studies.2-6<\/sup> AlloSure Lung has been validated to effectively identify a composite endpoint of acute cellular rejection (ACR), antibody-mediated rejection (AMR), and infection in asymptomatic lung transplant patients during routine surveillance screening.3<\/sup> The use of AlloSure Lung for surveillance has been shown to identify episodes of acute rejection and infection that may have been missed using a clinically-indicated biopsy strategy alone.3<\/sup> Additionally, when using an AlloSure Lung surveillance strategy, it was estimated that there were 83% fewer invasive biopsies than would have been performed under a surveillance biopsy protocol.3<\/sup> The high unmet need and clinical utility have led to the rapid adoption of AlloSure Lung, now used in over 60 percent of lung transplant centers in the U.S.7<\/sup><\/p>\n

\n\u201cAlloSure Lung has made a significant difference in non-invasively monitoring rejection and infection in lung transplant patients where allograft failure is a serious concern and early interventions are paramount to improving long-term outcomes,\u201d said Dr. Nirmal Sharma, Medical Director of the Lung Transplantation Program at Brigham and Women\u2019s Hospital. \u201cBy using this non-invasive test, we\u2019ve been able to implement more timely interventions. Additionally, in high-risk patients we have successfully reduced the number of surveillance bronchoscopies\/biopsies and avoided the inherent risks associated with these invasive procedures.\u201d<\/p>\n

\nAlloSure Lung\u2019s ability to offer early warnings to physicians of possible infection or organ rejection can help to inform timely therapeutic interventions. Lung transplant patients have one of the lowest median survivals of any solid organ transplant recipient, with a five-year survival rate of approximately 53 percent.8 <\/sup>Introduced in October 2021, AlloSure Lung has already been adopted in over 60 percent of lung transplant centers.7<\/sup><\/p>\n

About CareDx \u2013 The Transplant Company<\/b><\/p>\n

\nCareDx, Inc., headquartered in Brisbane, California, is a leading precision medicine solutions company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. CareDx offers testing services, products, and digital healthcare solutions along the pre- and post-transplant patient journey and is the leading provider of genomics-based information for transplant patients. For more information, please visit: www.CareDx.com<\/b><\/a>.<\/p>\n

Forward Looking Statements<\/b><\/p>\n

\nThis press release includes forward-looking statements related to CareDx, Inc., including statements regarding the potential benefits and results that may be achieved with AlloSure Lung and the favorable Medicare coverage determination for AlloSure Lung (the \u201cDetermination\u201d). These forward-looking statements are based upon information that is currently available to CareDx and its current expectations, speak only as of the date hereof, and are subject to risks and uncertainties that could cause actual results to differ materially from those projected, including risks that CareDx does not realize the expected benefits of AlloSure Lung and the Determination; general economic and market factors; and other risks discussed in CareDx\u2019s filings with the SEC, including the Annual Report on Form 10-K for the fiscal year ended December 31, 2022 filed by CareDx with the SEC on February 27, 2023, the quarterly report on Form 10-Q for the quarter ended March 31, 2023 filed by CareDx with the SEC on May 10, 2023, and other reports that CareDx has filed with the SEC. Any of these may cause CareDx\u2019s actual results, performance, or achievements to differ materially and adversely from those anticipated or implied by CareDx\u2019s forward-looking statements. CareDx expressly disclaims any obligation, except as required by law, or undertaking to update or revise any such forward-looking statements.<\/p>\n

References:<\/b><\/p>\n

    \n
  1. \nAlloSure Lung is covered by Medicare under MolDX LCD L38568 and using Z-code ZB9JM.<\/p>\n<\/li>\n
  2. \nTrindade AJ, Chapin KC, Mullican A, et al. Assessment of dd-cfDNA Levels in Clinically Stable Lung Allograft Recipients Beyond the Initial 2 y Posttransplant. Transplant Direct<\/i>. 2022 Nov 17;8(12): e1411. doi:10.1097\/TXD.0000000000001411. PMID: 36406896; PMCID: PMC9671749.<\/p>\n<\/li>\n
  3. \nKeller M, Sun J, Mutebi C, et al. Donor-derived cell-free DNA as a composite marker of acute lung allograft dysfunction in clinical care. J Heart Lung Transplant<\/i>. 2022 Apr;41(4):458-466. doi: 10.1016\/j.healun.2021.12.009. Epub 2021 Dec 26. PMID: 35063338.<\/p>\n<\/li>\n
  4. \nKeller M, Mutebi C, Shah P, et al. Biological Variation of Donor-Derived Cell-Free DNA in Stable Lung Transplant Recipients. J Appl Lab Med<\/i>. 2022 Jun 30;7(4):901-909. doi: 10.1093\/jalm\/jfab171. Erratum in: J Appl Lab Med. 2022 Nov 12; PMID: 35024828.<\/p>\n<\/li>\n
  5. \nKhush KK, De Vlaminck I, Luikart H, et al. Donor-derived, cell-free DNA levels by next-generation targeted sequencing are elevated in allograft rejection after lung transplantation. ERJ Open Res<\/i>. 2021 Jan 25;7(1):00462-2020. doi: 10.1183\/23120541.00462-2020. PMID: 33532456; PMCID: PMC7836440.<\/p>\n<\/li>\n
  6. \nSayah D, Weigt SS, Ramsey A, et al. Plasma Donor-derived Cell-free DNA Levels Are Increased During Acute Cellular Rejection After Lung Transplant: Pilot Data. Transplant Direct<\/i>. 2020 Sep 24;6(10): e608. doi: 10.1097\/TXD.0000000000001063. PMID: 33062841; PMCID: PMC7515612.<\/p>\n<\/li>\n
  7. \nCareDx data on file.<\/p>\n<\/li>\n
  8. \nEstimates based on OPTN (Organ Procurement and Transplantation Network). Graft survival rates for transplants performed. Accessed online at https:\/\/optn.transplant.hrsa.gov\/data\/view-data-reports\/national-data\/<\/a><\/li>\n<\/ol>\n

    \"\"<\/p>\n

    View source version on businesswire.com: <\/span>https:\/\/www.businesswire.com\/news\/home\/20230711873158\/en\/<\/a><\/span><\/p>\n

    \nCareDx, Inc.
    \n
    Media Relations
    \n
    Anna Czene
    \n
    818-731-2203
    \n
    aczene@caredx.com<\/a><\/p>\n

    \nInvestor Relations
    \n
    Greg Chodaczek
    \n
    investor@caredx.com<\/a><\/p>\n

    KEYWORDS:<\/b> California United States North America<\/p>\n

    INDUSTRY KEYWORDS:<\/b> Biotechnology Surgery Health Genetics Health Technology<\/p>\n

    MEDIA:<\/b><\/p>\n\n\n\n\n
    Logo<\/b><\/font><\/td>\n<\/tr>\n
    \"Logo\"<\/td>\n<\/tr>\n
    <\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

    CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring AlloSure Lung Represents First dd-cfDNA Approved by Medicare for Lung Transplant Patients BRISBANE, Calif.–(BUSINESS WIRE)– CareDx, Inc. (Nasdaq: CDNA) \u2013 The Transplant Company\u2122 focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers \u2013 today announced that CareDx\u2019s AlloSure\u00ae Lung donor-derived cell-free DNA (dd-cfDNA) molecular testing service has received Medicare coverage. The MolDX technology assessment program has determined that AlloSure Lung will be covered under the existing Medicare Local Coverage Determination for Molecular Testing for Solid Organ Allograft Rejection for use in the surveillance setting in lung transplant patients, effective May 9, 2023.1 \u201cCareDx was the first to … <\/p>\n

    Continue reading “CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-768836","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nCareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring AlloSure Lung Represents First dd-cfDNA Approved by Medicare for Lung Transplant Patients BRISBANE, Calif.–(BUSINESS WIRE)– CareDx, Inc. (Nasdaq: CDNA) \u2013 The Transplant Company\u2122 focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers \u2013 today announced that CareDx\u2019s AlloSure\u00ae Lung donor-derived cell-free DNA (dd-cfDNA) molecular testing service has received Medicare coverage. The MolDX technology assessment program has determined that AlloSure Lung will be covered under the existing Medicare Local Coverage Determination for Molecular Testing for Solid Organ Allograft Rejection for use in the surveillance setting in lung transplant patients, effective May 9, 2023.1 \u201cCareDx was the first to … Continue reading "CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring"\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2023-07-11T11:32:32+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&sty=20230711873158r1&sid=flmnd&distro=nx&lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring\",\"datePublished\":\"2023-07-11T11:32:32+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\\\/\"},\"wordCount\":1067,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&sty=20230711873158r1&sid=flmnd&distro=nx&lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\\\/\",\"name\":\"CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring - 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(Nasdaq: CDNA) \u2013 The Transplant Company\u2122 focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers \u2013 today announced that CareDx\u2019s AlloSure\u00ae Lung donor-derived cell-free DNA (dd-cfDNA) molecular testing service has received Medicare coverage. The MolDX technology assessment program has determined that AlloSure Lung will be covered under the existing Medicare Local Coverage Determination for Molecular Testing for Solid Organ Allograft Rejection for use in the surveillance setting in lung transplant patients, effective May 9, 2023.1 \u201cCareDx was the first to … Continue reading \"CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/","og_site_name":"Market Newsdesk","article_published_time":"2023-07-11T11:32:32+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&sty=20230711873158r1&sid=flmnd&distro=nx&lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring","datePublished":"2023-07-11T11:32:32+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/"},"wordCount":1067,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&sty=20230711873158r1&sid=flmnd&distro=nx&lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/caredxs-allosure-lung-dd-cfdna-testing-service-receives-medicare-coverage-for-lung-transplant-rejection-monitoring\/","name":"CareDx\u2019s AlloSure Lung dd-cfDNA Testing Service Receives Medicare Coverage for Lung Transplant Rejection Monitoring - 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